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: a disease that is characterized
by uncontrolled cell growth in an organ ,
i.e. The site the cells originate from.
: begins in the
breast tissue and may start in the
duct or lobe of the breast. When
the “controls” in breast cells are
not working properly, they divide
continually and a lump or tumor is
formed.
Most women will have
some lumpiness in their
breasts.
Most breast lumps are benign ,
mean not cancer.
Breast Cancer is most common in
women over 50 years of age.
is not common
in young women.
This means that less than one in more
than 2,000,000 young women will
develop breast cancer while they are
teenagers.
occurs due to a
mutation in two genes which
located in the chromosome 13
and 17 , which called by BRCA1
and BRCA2.
We should also know that only
about 5-10% of cases are due to
genes inherited from a person’s
parents.
most commonly develops in cells
from the lining of the milk ducts and the lobules that
supply the ducts with milk.
Cancers developing from the ducts are know as ductal
carcinomas, while those developing from lobules are
known as lobular carcinomas. In addition, there are
more than 18 other sub-types of breast cancer.
: something that may raise your chances of getting
a disease. It doesn’t mean you will get the disease.
Modifiable Risk Factors
• Gender
• Age
• Family history
• Breast density
• Early menstruation
• Late menopause
NON-Modifiable Risk Factors
• Radiation exposure
• Reproduction
• Breastfeeding
• Hormone replacement
therapy
• Oral contraceptives
• Body weight
• Physical activity
• Alcohol use
• Tobacco smoke
• A new lump
• A change in shape, size or color of
your breast
• A change in appearance of your nipple
• A spontaneous, new or bloody nipple
discharge.
 Mammograms
 Ultrasound
 MRI, Blood tests
 PET scans
for breast cancer is often a
combination of the following treatments:
• Removing the area of concern and some normal
tissue surrounding it is called a lumpectomy.
• Removing the breast is called mastectomy
(most women with breast cancer will not
need the breast removed).
• Lymph nodes from under
the arms may be removed
with either surgery.
• The use of combination of intravenous
drugs which affect breast cancer cells.
• Is called Systemic Treatment because
it affects whole body.
• Standard treatment after a lumpectomy to
reduce the chance of the breast cancer
coming back in the same breast.
• Is also called local treatment because it affects
only the area being treated with radiation.
• Growth of many breast cancers can be
blocked by taking hormone therapy.
• Treatment is in the form of a pill which is taken
for 5 years.
• May be recommended for women
who have a breast cancer that is
sensitive to hormones.
• Tamoxifen : anti-estrogen
compound in the estrogen-
receptor-positive patients
Breast cancer

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Breast cancer

  • 1.
  • 2. : a disease that is characterized by uncontrolled cell growth in an organ , i.e. The site the cells originate from. : begins in the breast tissue and may start in the duct or lobe of the breast. When the “controls” in breast cells are not working properly, they divide continually and a lump or tumor is formed.
  • 3. Most women will have some lumpiness in their breasts. Most breast lumps are benign , mean not cancer. Breast Cancer is most common in women over 50 years of age.
  • 4. is not common in young women. This means that less than one in more than 2,000,000 young women will develop breast cancer while they are teenagers.
  • 5. occurs due to a mutation in two genes which located in the chromosome 13 and 17 , which called by BRCA1 and BRCA2. We should also know that only about 5-10% of cases are due to genes inherited from a person’s parents.
  • 6. most commonly develops in cells from the lining of the milk ducts and the lobules that supply the ducts with milk. Cancers developing from the ducts are know as ductal carcinomas, while those developing from lobules are known as lobular carcinomas. In addition, there are more than 18 other sub-types of breast cancer.
  • 7.
  • 8. : something that may raise your chances of getting a disease. It doesn’t mean you will get the disease. Modifiable Risk Factors • Gender • Age • Family history • Breast density • Early menstruation • Late menopause NON-Modifiable Risk Factors • Radiation exposure • Reproduction • Breastfeeding • Hormone replacement therapy • Oral contraceptives • Body weight • Physical activity • Alcohol use • Tobacco smoke
  • 9. • A new lump • A change in shape, size or color of your breast • A change in appearance of your nipple • A spontaneous, new or bloody nipple discharge.  Mammograms  Ultrasound  MRI, Blood tests  PET scans
  • 10. for breast cancer is often a combination of the following treatments:
  • 11. • Removing the area of concern and some normal tissue surrounding it is called a lumpectomy. • Removing the breast is called mastectomy (most women with breast cancer will not need the breast removed). • Lymph nodes from under the arms may be removed with either surgery.
  • 12. • The use of combination of intravenous drugs which affect breast cancer cells. • Is called Systemic Treatment because it affects whole body.
  • 13. • Standard treatment after a lumpectomy to reduce the chance of the breast cancer coming back in the same breast. • Is also called local treatment because it affects only the area being treated with radiation.
  • 14. • Growth of many breast cancers can be blocked by taking hormone therapy. • Treatment is in the form of a pill which is taken for 5 years. • May be recommended for women who have a breast cancer that is sensitive to hormones. • Tamoxifen : anti-estrogen compound in the estrogen- receptor-positive patients