CIO Bulletin has published an issue of 10 Best Inspiring Leaders of the Year 2021.

1. 10 Best Inspiring Leaders of the Year 2021
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Lori Hamilton | Founder | President
Prosperity Productions: Helps
You Understand What Your
Customers Truly Want
November 2021
Scot Parnell, CFO
CFO of the month
DailyPay
Sean James Miller, CEO
& Chief Scientific Officer
CEO of the Year
Pluripotent Diagnostics Corp

2. Creator of novel technologies in cross-disciplinary areas to
identify and administer personalized therapeutic interventions
for genetic disorders — Sean James Miller, CEO & CSO of
Pluripotent Diagnostics (PDx)
N
eurodegenerative
diseases are prevalent
and a significant
source of healthcare
expenditure. Numerous studies
have demonstrated that the
development of neurodegenerative
diseases such as Alzheimer’s,
Parkinson’s, Huntington’s diseases,
vascular, and frontotemporal
dementias begin nearly 10-
20 years prior to the clinical
manifestation. With a wealth of
digital, scientific, and medical data
at our fingertips, now is the time
to transform the early detection of
neurodegenerative diseases. Today
the diseases that cause dementia
are diagnosed when symptoms like
memory loss start. To have the
best chance of halting them, we
need to intervene decades earlier,
when these diseases first begin to
take hold.
While most institutions around
the world are speculating that
in the future, companies can
use digital fingerprints to help
doctors detect the early stages
of neurodegenerative diseases
like Alzheimer’s or Parkinson’s,
Dr. Sean James Miller and his
team at Pluripotent Diagnostics
have created patented solutions
to enable early detection of
neurodegenerative and genetic
diseases and administer
personalized therapeutic
interventions to patients of any
age. Dr. Miller and Pluripotent
Diagnostics envision a world free
of genetic disorders.
Dr. Sean James Miller,
Chief Executive Officer
& Chief Scientific
Officer, exclusively
spoke to CIO Bulletin.
Below is an excerpt of
the conversation.
What are the most
important attributes of
successful leaders today?
I view leadership in two words,
fearless guardian. A fearless
guardian takes the hardest
hits and weakens them for the
team to continue to push while
ensuring the team’s success.
path you took to get to
where you are today?
For most people, life isn’t easy.
Especially in adolescence. I
grew up in an undesirable area
of Pennsylvania. The thing I am
motivated by the most, to date,
is never to end up going back.
A pivotal moment in my life was
during my senior year of high
school involving my calculus
teacher, Mr. Neiswender, who
drove me to dream big, and
that’s precisely what I did.
A Relentlessly Reliable Leader
Sean James Miller, PhD is the Chief Executive Officer and Chief Scientific Officer of Pluripotent Diagnostics
(PDx). He has over 13 years’ experience in stem cell, neurodegenerative, and genetic medicine. He completed
his pre-doctoral, doctoral, and post-doctoral research at Drexel, Harvard Medical School, Johns Hopkins
School of Medicine, and Stanford School of Medicine. Dr. Miller has over 15 authored publications in top
tier journals, including: Science, Neuron, Nature, and Nature Neuroscience and his papers have been cited
over 1500 times in peer-reviewed scientific publications. Dr. Miller holds patents on drug development and
gene therapy for neurodegenerative disorders.
CEO of the Year
2021-November | 2

3. In 2008, I left my hometown and
started my career in molecular
medicine. During my time as an
undergraduate, apart from my
academic scholarship, I had no
other source of income. I couldn’t
afford rent, food, or a traditional
lifestyle. With the motivation to
never “go back,” I found myself in
a molecular Alzheimer’s disease
laboratory. In no time, I was
fully dedicated and grew deeply
passionate about neurobiology.
Three years later, I graduated with
a degree in Organismal Physiology
and Molecular Biology. I continued
my medical research at Harvard
Medical School with Dr. Rudolph
Tanzi to further the understanding
of underlying neurogenetics in
Alzheimer’s disease. Throughout
my time at Harvard, I had the
opportunity to contribute to
leading studies published in
top-tier journals such as Science.
Five years after starting my
undergraduate research, I was
admitted into the Molecular and
Cellular Medicine program at the
Johns Hopkins University School
of Medicine. My dissertation was
heavily focused on identifying
novel cell types in the adult
brain. Mainly, I found a recently
unidentified non-neuronal cell
that contributes to the overall
communication of neurons in
health and disease.
In 2018, I defended my thesis and
relocated to Stanford University
School of Medicine to conduct
my studies on the demise of
the blood-brain barrier in aging
and aging-associated diseases
with Dr. Tony Wyss-Coray. A
year later, I founded Pluripotent
Diagnostics (PDx) in my Mountain
View apartment in Silicon
Valley with the sole mission to
eliminate genetic diseases such
as Amyotrophic Lateral Sclerosis
(ALS) and Alzheimer’s disease.
What have been the biggest
challenges you’ve had to
overcome?
Maintaining the world’s best
team is nearly impossible without
funding. As PDx advances and
makes significant strides in early
disease detection, this is becoming
less of an issue. Nonetheless, this
formulated the strongest team
to cope with the challenges that
entail a developing organization.
How do you keep your
team motivated despite
conflicts and obstacles?
Each team member comes with
different experiences and requires
a unique approach to their
motivation. With that said, I take
a holistic method by individually
understanding my team members
both in work and life.
Sean James Miller, PhD
CEO & Chief Scientific Officer
CEO of the Year

4. TigerConnect: Healthcare’s Leading
Collaboration Platform, Delivering
over 2 Billion Messages a Year
M
odern healthcare
facilities are filled
with miraculous
care tools, but their
communications systems are
broken. TigerConnect solves this
problem – with a simple mobile
app, so the right person receives
the right message with the right
data at the right time.
Founded in 2010, TigerConnect
is healthcare’s most widely
adopted communication
platform – uniquely modernizing
care collaboration among
doctors, nurses, care teams, and
patients. TigerConnect is the
only solution that combines a
consumer-like user experience
for both clinical and patient
communication with serious
security, privacy, and clinical
workflow requirements that
today’s healthcare organizations
demand. TigerConnect accelerates
productivity, reduces costs, and
improves patient outcomes.
Trusted by more than 6,000
healthcare organizations,
TigerConnect maintains 99.99%
verifiable uptime and processes
more than 10 million messages
each day.
The TigerConnect portfolio
helps healthcare organizations
solve complex workflows and
communications scenarios with a
single care collaboration platform.
Additional capabilities include
patient and family engagement,
alert and event notification, and
clinical staffing solutions.
The TigerConnect portfolio helps
health systems solve complex
workflows and communications
scenarios with a single care
collaboration platform. Additional
capabilities include patient and
family engagement, alert and
event notification, and clinical
staffing solutions.
TigerConnect Alarm
Management & Event
Notification
TigerConnect Alarm Management
& Event Notification interfaces
with nurse call systems,
physiological monitors, EHR/
critical lab results, smart beds,
and more to acquire alarms,
events, and values. Using a
configurable workflow, context-
rich notifications are routed
to the appropriate caregiver.
As an integrated component
of the TigerConnect Clinical
Collaboration Platform, the
solution offers a wide range of use
cases for healthcare organizations
of any size.
TigerConnect Alarm Management
& Event Notification intelligently
routes actionable alarms to
caregivers on their mobile devices.
If there is no response to an alarm
within a preset amount of time, it
will be escalated to another care
team member. The assignments
and workflow builder enable
routing and escalation of alerts
that are infinitely configurable.
TigerConnect Alarm Management
& Event Notification is a cyber-
secure, FDA Class II Medical
Device for Secondary Alert
Notification. The solution
conforms to industry best practices
of distributed, multi-tenant
architecture and features full
extensibility and scalability. The
system’s Software-as-a-Service
(SaaS) avoids large capital outlays,
helping IT teams to reduce annual
operating costs.
“As hospitals confront chronic
staffing shortages and drops in
revenue from reduced elective
procedures, they face pressure to
work more efficiently. But they
also want to keep nurses front and
center as they consider the workload
and mental health stress caused
CIO Bulletin | 10 Best Inspiring Leaders of the Year 2021

5. by notification fatigue,” said Dr.
Will O’Connor, TigerConnect
chief medical information officer.
“Solving this problem is core to
TigerConnect’s mission. We’re
gratified to see how our Alarm
Management & Event notification
solution is solving some of the biggest
care delivery challenges facing
healthcare organizations today.”
TigerConnect has successfully
deployed Alarm Management
and Event Notification at
numerous client sites across the
United States. These include an
850-bed health system in the
northeast, which has connected
Rauland Responder IV & V,
Stanley Healthcare RTLS, and
Philips & Masimo monitors
to the TigerConnect Clinical
Collaboration Platform on iOS.
A 100-bed medical center,
also in the northeast, replaced
their middleware offering and
connected the TigerConnect
Clinical Collaboration Platform
including Alarm Management
and Event Notification to a nurse
call system, Stanley Healthcare
RTLS, and Mindray physiological
monitors on Zebra Phones.
TigerConnect makes it possible
for healthcare providers to
maximize investments in their
existing clinical systems, such
as Electronic Health Records
systems while reaping additional
benefits. They can modernize their
communication and collaboration
capabilities by leveraging
TigerConnect’s platform,
integration engine, advanced
clinical workflow builder, and staff
assignment client—coupled with
a world-class clinical workflow
analytics solution.
“With TigerConnect, you may not
have to replace your various clinical
systems in order to upgrade feature-
sets, integrations, or reporting
capabilities,” says John Elms,
TigerConnect chief product officer.
“Your IT teams can deploy our
modern, cybersecure middleware,
providing an intuitive end-user UX,
an extensive library of integrations,
and enhanced analytics engine at a
fraction of the cost. Your teams can
also consolidate vendors, replacing
costly SMAs and other service
agreement schemas with a single,
SaaS-based approach.”
TigerConnect’s unique software
architecture offers cloud-based
scalability, cybersecurity, high
availability, and multi-tenancy
to hospitals and healthcare
enterprises. By buying only
what they need, hospitals and
healthcare enterprises can
strategically scale over time, with
purpose-built flexibility, reliability,
and a low total cost of ownership.
Brad Brooks, Chief Executive
Officer
Brad previously ran DIC Entertainment as President
for six years after working for Donaldson, Lufkin and
Jenrette as an Investment Banker. After acquiring
the company with Bain Capital from the Walt Disney
Company in 2000, he helped grow the company
from less than $10 million of revenues to over $80
million in 2005 when he took the company public
on the London Stock Exchange at a $200 million
valuation. Brad received his BA from UC Berkeley
and an MBA from the University of Chicago.
Brad Brooks, CEO
The TigerConnect portfolio helps healthcare organizations
solve complex workflows and communications scenarios
with a single care collaboration platform.
“

6. ClearScale –
Delivering a
Complete Range of
Cloud Computing
Services from Strategy
to Development and
Implementation
C
loud computing offers
your business many
benefits. It allows you to
set up what is essentially
a virtual office to give you the
flexibility of connecting to your
business anywhere, any time.
With the growing number of
web-enabled devices used in
today’s business environment (e.g.
smartphones, tablets), access to
your data is even easier. Moving to
cloud computing may reduce the
cost of managing and maintaining
your IT systems.
ClearScale is a cloud-native
systems integration, strategic
consulting, and application
development company. The
company designs, builds,
integrates, and manages complex
infrastructures and applications
on AWS exclusively. It has
successfully delivered more than
900 cloud projects for clients
ranging from startups to large
enterprises and public sector
organizations. Its core competency
is delivering custom cloud projects
and services for clients who have
limited cloud experience on staff
or who need additional resources.
The company leverages the best
cloud technology available to
provide a solution that is unique
to your project requirements.
Whether this is your first project
in the cloud or one of many,
ClearScale has the expertise
to handle your most complex
requirements.
Next-Generation
Cloud-Based Services
Offered
Cloud Application Development
Services: Build and deploy
resilient cloud applications at scale
with ClearScale’s cloud application
development services. ClearScale
develops performance and highly-
available cloud applications using
proven and cutting-edge cloud
technologies. They also perform
application modernization services
to adapt your legacy applications
to run on the cloud. In addition,
they offer traditional web and
mobile application development
services in the most common
platforms and languages like iOS,
Android, Ruby, Python, PHP, Java,
Node.js, and more. As your full-
service cloud partner, ClearScale
can help develop your strategic
and tactical plan for using
AWS services based on the best
practices that they’ve developed
across hundreds of successful
client engagements.
Cloud Migration Services:
ClearScale is an Amazon Web
Services (AWS) Premier Consulting
Partner because of its proven
capability to migrate complex
architectures to the cloud and
its deep knowledge of Amazon’s
best-in-class services. Moving
to the cloud is one of the first
and most important steps in
Pavel Pragin
CEO & CTO

7. successfully growing your business
and achieving the benefits of
cost efficiency, agility, and
scalability. The company has a
long track record of delivering
successful cloud migration
services for clients of all sizes
in a wide variety of industries.
They take planning seriously and
strive for a seamless transition of
your valuable data to the cloud
with zero downtime. They have
experience in migrations from
internal data centers as well as
other cloud providers such as
Rackspace, SoftLayer, Google
Compute Engine, Microsoft Azure,
and Joyent. ClearScale’s high level
of expertise with Amazon Web
Services (AWS) enables them to
extend the benefits of AWS’s most
advanced and cost efficient cloud
migration services to their clients.
Cloud Technology Services:
The company offers the full
range of Big Data services,
including architecture design and
infrastructure migration, data
integration, systems integration,
automation, management, and
application development using
AWS Big Data services. Its Big
Data solutions are scalable,
efficient, and cost-effective. Big
Data management solutions give
companies the ability to collect a
multitude of data from hundreds
of sources in real time, resulting
in better customer engagement
through more effective interactions
and marketing programs. Big Data
analytics provide organizations
with comprehensive customer
profiles, enabling the delivery of
more personalized service and
experiences, ultimately leading to
greater customer lifetime value.
ClearScale utilizes powerful AWS
Big Data services in the majority
of its projects to enable the clients
to stream, store, and process
vast amounts of data for their
customer-facing applications.
ClearScale Managed Services:
Focus on your business instead
of cloud operations when you
enlist ClearScale Managed
Services. With its robust tool set
and experienced engineers, the
company’s Managed Services team
can help you reduce your costs
and improve the efficiency of your
cloud infrastructure. Its trusted
team provides 24/7 monitoring,
and services related to all AWS
products. Select from a variety
of service tiers to meet your
specific managed services needs
and budget. ClearScale will set up
24/7 monitors and alerts for your
cloud infrastructure, applications,
and dependent services to help
you ensure everything is available,
healthy, secure, and efficient.
The Pre-Eminent Leader
Pavel Pragin is the Chief Executive Officer and Chief Technology Officer of ClearScale. He
is an innovator in the fields of cloud computing, high availability, scalability, security, and
application development. With over 17 years of industry experience, he has a long track record
in working with cutting-edge technologies and implementing enterprise-level cloud solutions.
Pavel leverages his systems engineering and management experience to ensure that customer
business requirements are met. Pavel enjoys hiking, mountain biking, golf, and skiing.
Whether you’re looking to reduce IT
expenditures, improve operational efficiency,
increase business agility, accelerate innovation,
or mitigate risk, ClearScale is your partner.
“
”
7 | November-2021
CIO Bulletin | 10 Best Inspiring Leaders of the Year 2021

8. F
ounded in 2013, SyncDog is
the leading ISV for building
mobile frameworks that
extend app functionality to
devices while securing corporate
and government networks from
mobile-endpoint threats.
The company’s flagship solution,
Secure.Systems, delivers a rich
and unimpeded mobile experience
for employees working remotely,
and supports a multitude of
enterprise productivity apps within
a NIST-certified (FIPS 140-2 cert.
#2687) workspace. The solution
is ideal for organizations that
want to deliver a rich mobile app
experience across BYOD, CYOD
(choose your own device), or other
endpoint device policy. Secure.
Systems is a natural complement
to security and compliance
auditing initiatives to satisfy the
mandates of HIPAA, GDPR, PCI
DSS, GLBA, FISMA, and other
laws/standards for data security.
BYOD or COPE Mobile
Device Management
Employees should be able to do
their work from wherever they are.
SyncDog combines a suite of office
applications (email, calendar,
contacts, office editor, file share,
location services, messaging etc)
along with an architecture that
protects and secures your mobile
workforce through FIPS 140-2,
AES 256 bit encryption that finally
removes the technological struggle
of having to choose between
increased security or increased
productivity. SyncDog enables you
to have both.
Secure.Systems™
easily integrates
into existing endpoint management
solutions and can be deployed
from the cloud, on-premise or as a
hybrid deployment.
Secure, Mobile
Healthcare
Environment
Physicians and healthcare
providers need to use mobile
devices to communicate with
patients and share data
effectively within the patient
care continuum. Keeping that
data secure has never been more
important or more difficult.
Meeting HiPAA compliance in a
world with over 165,000 health
apps, a growing number of cyber
threats, and hackers around
every corner is more than just
challenging.
Secure. Systems is a containerized
mobile workspace solution
delivered from the cloud that
creates a more secure, protected
environment for healthcare data
and applications. It separates,
encrypts and protects the
enterprise data from hackers. It
keeps personal apps separate from
hospital apps with separate rules
for behavior and protects each
from contamination.
Partnership with
Deltek Marketplace to
Empower Compliance
Today, organizations all over
the world in both the public
and private spheres are using
and generating a huge amount
of mobile data. But the current
policies in the above mentioned
sectors fall far short on security,
compliance, and productivity.
Because of this, the U.S.
Federal Government is asking
organizations across the country
“Secure.Systems™
easily integrates into existing
endpoint management solutions and can be deployed
from the cloud, on-premise or as a hybrid deployment.”
SyncDog: Challenges the Status
Quo and Changes the Game on
How Organizations Empower
Their Mobile Workforce

9. that access or share government
data – including commercial
companies that do contract-based
work for the government – go
to great lengths to prove that
government data is only being
viewed and shared with only
those who are authorized to use
it. So, it is important that these
organizations achieve compliance
and adopt the cybersecurity
and data protection standards
outlined in industry frameworks
in more critical than ever.
Acting on this, SyncDog
announced that it is joining
Deltek’s Marketplace to bring
the first fully integrated
end-to-end mobile security
solution to global enterprises
and government agencies.
Through this partnership with
Deltek, the leading global
provider of software and
solutions for project-based
businesses, SyncDog will help
government contractors and
other organizations rapidly
deploy a zero-trust security
framework across their mobile
endpoint landscape to comply
with the requirements outlined
in the Cyber Maturity Model
Certification (CMMC), NIST
800-171 and other regulations
focused on data protection and
privacy.
SyncDog’s Secure.Systems,
provides a holistic, zero-trust
approach that helps bring
organizations into compliance
with CMMC, NIST 800-171 and
other cyber and data privacy
regulations without requiring
a trade-off in security and
productivity. SyncDog’s unified
Trusted Mobile Workspace
(TMW) provides validated
FIPS 140-2 level security
against advanced mobile cyber
threats and streamlines device
management to make achieving
compliance with internal and
external regulations an easy step.
“As seen most recently with the
Pegasus spyware attacks, mobile
phones are being heavily targeted
by cybercriminals. Our addition
to the Deltek Marketplace will
help equip organizations with the
critical mobile security, compliance,
and productivity tools they need
to continue – and improve –
business operations securely and
efficiently. Government contractors
and other organizations will
have peace of mind knowing that
our technology has simplified
the process of complying with
emerging regulations, and
maybe more importantly, greatly
minimized their attack surface
while enabling autonomy and
data privacy for employees,” said
Brian Egenrieder, Chief Revenue
Officer at SyncDog.
Jonas Gyllensvaan, Founder
and CEO
The successful founder of multiple mobility
technologies companies, Jonas has been
a leader in the information technology
marketplace for over 20 years. He has
specifically been exploring advancements
in mobile device security since the 1990s.
His focus as the Founder and CEO of SyncDog
is continual product enhancement; he takes
client feedback to heart, and then he takes
it to R&D. His bachelor’s in Mechanical
Engineering from Högskolan i Halmstad
in Sweden and cybersecurity courses from
Harvard University are the roots of his
passion for innovating technologies for
modern operational environments. Jonas’s
ability to constantly innovate solutions to
business technology pain points is what
has led SyncDog to become a leading
independent software vendor (ISV) for
enterprises of all sizes.
Jonas Gyllensvaan, Founder & CEO
CIO Bulletin | 10 Best Inspiring Leaders of the Year 2021