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TRANS ORAL ROBOTIC
SURGERY
Prof. S. Subbiah et al
HISTORY
• In 1985 - stereotactic brain biopsy was taken
by PUMA SYSTEM.( Programmable universal
manipulation arm )
• In 1995 -Da vinci surgical system was
developed.
• In 2000 -FDA gave approval for first robotic
surgeries.
Prof. S. Subbiah et al
PUMA ARM
Prof. S. Subbiah et al
First otolaryngology application in
robotics kick started in 2002 -endoscopic neck
procedures
First application in humans was described
by mcloed in 2005 - documented excision of
vallecular cyst .
In 2009 FDA approved Da vinci surgical
system for TORS for lesions in pharnyx and
larynx.
Prof. S. Subbiah et al
TORS
• DA VINCI ROBOTIC SYSTEM
• FLEX ROBOTICSYSTEM (MEDROBOTICS)
Prof. S. Subbiah et al
DA VINCI (TORS)
The Da Vinci Surgical System consists of three components:
a surgeon’s console,
a patient-side robotic cart equipped with four arms,
a high-definition three-dimensional vision cart.
Typically, three robot arms are introduced into the oral
cavity:
an endoscope,
tissue forceps and a cutting tool,
usually a carbon dioxide laser or an electrocautery
Prof. S. Subbiah et al
Prof. S. Subbiah et al
One to handle a 12-mm stereoscopic
endoscope at an angle of 0° or 30.
• The other two equipped with 5-mm endo
wrist (5 mm Maryland dissector and 5 mm
monopolar spatula).
Prof. S. Subbiah et al
FLEX ROBOTIC SYSTEM
• The Flex robotic system from MedRobotics was FDA
approved for transoral use in July of 2015.
• This robotic system is unique as it is a flexible snake
like device that can be manipulated easily in oral
cavity compared to daVinci robot (rigid arms).
Prof. S. Subbiah et al
EXPOSURE
• Transoral exposure of the tumor was
achieved using the
• Feyh-Kastenbauer retractor (Gyrus,
Tuttlingen, Germany)
• Crowe-Davis retractor,
• laryngeal advanced retractor system (Fentex,
Tuttlingen Germany).
Prof. S. Subbiah et al
Feyh-Kastenbauer retractor
Prof. S. Subbiah et al
laryngeal advanced retractor
system
Prof. S. Subbiah et al
Crowe-Davis retractor
Prof. S. Subbiah et al
STEPS OF DOCKING
• Position the patient and Operating table, including
table tilt.
• Position patient cart over patient.
• Set patient cart brakes.
• Docking the camera arm.
• Docking the instrument arms.
Prof. S. Subbiah et al
APPLICATIONS
• Lesions of the Palate
• Palatine tonsils
• Base of the tongue,
• Posterior and lateral pharyngeal wall
• Parapharyngeal space
• Larynx and hypopharynx
• Thyroid
Prof. S. Subbiah et al
Oncological indications
• TORS Tonsillectomy,
• Tongue base resection,and
• Supraglottic laryngectomy are the three most
common robotic applications in the head and neck
malignancy.
Prof. S. Subbiah et al
PROCEDURE
Prof. S. Subbiah et al
Patient positioning and preparation
• Universally the surgeons cart placed on the right
side patient ,and patient in supine position.
• Intubation may be done transorally or
transnasally.
Transnasal intubation is often advantageous in
Base of tongue tumours, whereas transoral intubation is
acceptable in tonsillar dissection
•. Secure the endotracheal tube with tape or a
suture.
• Place eye protection with durable eye shields.
Prof. S. Subbiah et al
DOCKING
• Once adequate suspension and tumour
visualisation are achieved, the robot is docked
transorally.
• 0-degree cameras are generally best for tonsil
tumours and 30-degree for BOT.
• The Maryland dissector and monopolar cautery are
commonly used robotic instruments.
• The monopolar cautery is typically positioned
ipsilateral to the tumour.
Prof. S. Subbiah et al
ROBOTIC MARYLAND
Prof. S. Subbiah et al
ROLE OF ASSISTANT
• Should be positioned in a way to see the display on
the vision cart properly.
• Has an essential role to suctioning the smoke,
providing clear field by clearing blood and provide
tension/ counter tension and exposure.
Prof. S. Subbiah et al
• The average set-up time after preliminary
experience for TORS is about 30 minutes or less.
Prof. S. Subbiah et al
Prof. S. Subbiah et al
Prof. S. Subbiah et al
TONGUE BASE
• Early lesion involving base of tongue (T1/T2)
• Transoral robotic base of tongue resection has been
found to be useful in a diagnostic capacity in the
setting of unknown primary head and neck
malignancy.
• The angled scopes improves visualization and helps
the surgeon to navigate around corners, as is often
needed in tongue base surgery
Prof. S. Subbiah et al
TONGUE BASE
STEP 1 : Anterior mucosal incision - jus behind the
retractor , not more than 1 cm depth
STEP 2 : Medial incision -Anterior to posterior till the
vallecula is reached.
STEP 3 : Lateral incision -proceed from lateral to
medial .Continue the mucosal incision across the
glossotonsillar sulcus then along the lateral
pharyngeal wall up to the vallecula
Prof. S. Subbiah et al
• STEP 4 : Vallecular dissection
• STEP 5 : Specimen orientation and frozen for
margins
• STEP 6 :Hemostasis.
Prof. S. Subbiah et al
TONSILLAR AREA
• Studies have shown that surgery is highly effective
in treating tonsillar cancer and provides accurate
staging information for adjuvant therapy.
Prof. S. Subbiah et al
• Weinstein et al. described TORS for radical
tonsillectomy in 27 patients with invasive
squamous cell carcinoma of the tonsil.
Prof. S. Subbiah et al
• Unresectable neck nodes
• Mandibular invasion,
• Involvement of >50% of the tongue base,
• Involvement of >50% of the posterior pharyngeal
wall,
• Carotid artery involvement.
• Fixation to prevertebral fascia.
Prof. S. Subbiah et al
TORS SUPRAGLOTTIC
LARYNGECTOMY
1) Patients with adequate transoral exposure of
the surgical field;
2) T1 or T2 supraglottic carcinoma;
3) Selected T3 supraglottic carcinoma with mobile
vocal cords (with or without preepiglottic space
invasion); and
4) tumors with minimal pyriform sinus involvement.
Prof. S. Subbiah et al
CONTRAINDICATIONS
• 1) Limited transoral exposure (ie, trismus, macroglossia,
micrognathia, or retrognathia);
• 2) Poor pulmonary reserve (FEV1/FVC <50%);
• 3) Tumor involvement of the thyroid cartilage or
anterior commissure;
• 4) Vocal cord fixation or paraglottic space invasion;
• 5) Bilateral arytenoid cartilage involvement;
• 6) Tumor extension into pyriform apex or postcricoid
mucosa.
Prof. S. Subbiah et al
Prof. S. Subbiah et al
TORT ( TRANS ORAL ROBOTIC
THYROIDECTOMY)
• In 2009, Benhidjeb et al. reported the first series of
transoral thyroidectomy.
• The central camera was passed through a
sublingual incision.
• The two lateral working arms passed through
vestibular incisions anterior to the mandible.
Prof. S. Subbiah et al
TOR/ETVA
In 2011, Richmon et al. modified this approach to
avoid the floor of mouth route.
All three ports were placed through the
vestibule anterior to the mandible to access the
subplatysmal space and the floor of mouth was not
violated.
Prof. S. Subbiah et al
Prof. S. Subbiah et al
OTHERS
• Infratemporal fossa Resection
• Robotic-assisted microvascular anastomosis
• First two cases of TORS-assisted free flap (radial
forearm) reconstruction carried out successfully .
Prof. S. Subbiah et al
NECK
• Positive neck nodes
• Patients with high risk (≥20%) for occult nodal
involvement.
• Neck dissections (uni- or bilateral) can be
performed immediately before or after the TORS
procedure or as a second-stage procedure.
Prof. S. Subbiah et al
SHIFT OF PARADIGM
Prof. S. Subbiah et al
• Cracchiolo et al discovered a steep rise of patients
with low T-status (T1–T2) OPSCC who underwent
primary surgical treatment.
• Total cases 3071
• TORS 846 (27.6%)
• In 2010 137 patients were treated with TORS,
• In 2013 280 patients were treated with TORS.
Prof. S. Subbiah et al
ABSOLUTE CONTRAINDICATION
• Reduced mouth opening.
• Incomplete lesion visualisation.
• Mandible involvement.
• Tumours involving >50% of the base of the tongue.
• Internal carotid artery, or prevertebral fascia
involvement.
Prof. S. Subbiah et al
BENEFITS
• Primary TORS- possible alternative to non-surgical
organ preservation regimen
• Up-front TORS - deintensification of adjuvant
therapy.
• Patients who would have received definitive RT as a
single modality treatment could avoid it with
primary TORS and possible complications of
radiation therapy .
Prof. S. Subbiah et al
• swallowing outcomes
• More et al. compared functional
swallowing out-comes after TORS with outcomes
after primary chemoradiation therapy tonsillar
cancer. They found significantly better scores of the
MD Anderson Dysphagia Inventory (MDADI) at 6
and 12 months postoperatively for those patients
who underwent TORS.
Prof. S. Subbiah et al
• 10x magnification results in improved
visualisation and the ability to resect lesions
en bloc in the oropharynx.
• Biology of disease and exact pathological
report can be obtained.
• TORS may avoid disfiguring surgeries.
Prof. S. Subbiah et al
• Recent studies found out that surgical
staging alters clinical staging in 40% after
TORS
• The robotic arms also filter tremors,
allowing precision with microscopic
movements.
Prof. S. Subbiah et al
Prof. S. Subbiah et al
ONCOLOGICAL OUTCOMES
Meta analysis.
Compared primary TORS with Open surgery.
TORS showed lower mortality rate , recurrence rate
and positive margin rates compared with open surgery.
But no significant statistical difference between two
groups.
Disease-free survival rate was significantly higher in
the TORS group than open surgery group.
Prof. S. Subbiah et al
FUNCTIONAL OUTCOMES
• Park et al. evaluated prospectively the functional
outcomes of patients treated with TORS in comparison
with patients treated conventionally with transoral
approach or mandibulotomy during the same period of
the study.
• There was a significant difference in swallowing, time to
decannulation, and hospitalization period between the
two groups.
• In the TORS group, patients completely recovered the
ability to swallow after 6 days. In contrast, patients
undergoing conventional surgery did not completely
recover their swallowing until 12 days.
Prof. S. Subbiah et al
DISADVANTAGES
• Ruptures during TORS are not unusual due to
manipulation by the Maryland forceps and could be
misinterpreted by the pathologist as being a
compromised margin.
• Cost effectiveness.
• Long learning curve.
Prof. S. Subbiah et al
COMPLICATIONS
• Hemorrhage
• Hematoma
• Wound infection
• Nerve palsy
• Aspiration related infection
• Rarely fistula.
• complication rates are much less compared to
open surgery or radiation therapy.
Prof. S. Subbiah et al
Debatable
• For comparing TORS with chemoradiation in terms of
overall survival and disease free interval we need more
RCT and worldwide adoption of TORS
Prof. S. Subbiah et al
RECENT
There are two techniques that are likely to improve
margin control in TORS,
Intelligent Knife technology.
Narrow band imaging
Intra-Operative Fluorescence Imaging.
Prof. S. Subbiah et al
THANK YOU
Prof. S. Subbiah et al

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TORS.pptx

  • 2. HISTORY • In 1985 - stereotactic brain biopsy was taken by PUMA SYSTEM.( Programmable universal manipulation arm ) • In 1995 -Da vinci surgical system was developed. • In 2000 -FDA gave approval for first robotic surgeries. Prof. S. Subbiah et al
  • 3. PUMA ARM Prof. S. Subbiah et al
  • 4. First otolaryngology application in robotics kick started in 2002 -endoscopic neck procedures First application in humans was described by mcloed in 2005 - documented excision of vallecular cyst . In 2009 FDA approved Da vinci surgical system for TORS for lesions in pharnyx and larynx. Prof. S. Subbiah et al
  • 5. TORS • DA VINCI ROBOTIC SYSTEM • FLEX ROBOTICSYSTEM (MEDROBOTICS) Prof. S. Subbiah et al
  • 6. DA VINCI (TORS) The Da Vinci Surgical System consists of three components: a surgeon’s console, a patient-side robotic cart equipped with four arms, a high-definition three-dimensional vision cart. Typically, three robot arms are introduced into the oral cavity: an endoscope, tissue forceps and a cutting tool, usually a carbon dioxide laser or an electrocautery Prof. S. Subbiah et al
  • 8. One to handle a 12-mm stereoscopic endoscope at an angle of 0° or 30. • The other two equipped with 5-mm endo wrist (5 mm Maryland dissector and 5 mm monopolar spatula). Prof. S. Subbiah et al
  • 9. FLEX ROBOTIC SYSTEM • The Flex robotic system from MedRobotics was FDA approved for transoral use in July of 2015. • This robotic system is unique as it is a flexible snake like device that can be manipulated easily in oral cavity compared to daVinci robot (rigid arms). Prof. S. Subbiah et al
  • 10. EXPOSURE • Transoral exposure of the tumor was achieved using the • Feyh-Kastenbauer retractor (Gyrus, Tuttlingen, Germany) • Crowe-Davis retractor, • laryngeal advanced retractor system (Fentex, Tuttlingen Germany). Prof. S. Subbiah et al
  • 14. STEPS OF DOCKING • Position the patient and Operating table, including table tilt. • Position patient cart over patient. • Set patient cart brakes. • Docking the camera arm. • Docking the instrument arms. Prof. S. Subbiah et al
  • 15. APPLICATIONS • Lesions of the Palate • Palatine tonsils • Base of the tongue, • Posterior and lateral pharyngeal wall • Parapharyngeal space • Larynx and hypopharynx • Thyroid Prof. S. Subbiah et al
  • 16. Oncological indications • TORS Tonsillectomy, • Tongue base resection,and • Supraglottic laryngectomy are the three most common robotic applications in the head and neck malignancy. Prof. S. Subbiah et al
  • 18. Patient positioning and preparation • Universally the surgeons cart placed on the right side patient ,and patient in supine position. • Intubation may be done transorally or transnasally. Transnasal intubation is often advantageous in Base of tongue tumours, whereas transoral intubation is acceptable in tonsillar dissection •. Secure the endotracheal tube with tape or a suture. • Place eye protection with durable eye shields. Prof. S. Subbiah et al
  • 19. DOCKING • Once adequate suspension and tumour visualisation are achieved, the robot is docked transorally. • 0-degree cameras are generally best for tonsil tumours and 30-degree for BOT. • The Maryland dissector and monopolar cautery are commonly used robotic instruments. • The monopolar cautery is typically positioned ipsilateral to the tumour. Prof. S. Subbiah et al
  • 20. ROBOTIC MARYLAND Prof. S. Subbiah et al
  • 21. ROLE OF ASSISTANT • Should be positioned in a way to see the display on the vision cart properly. • Has an essential role to suctioning the smoke, providing clear field by clearing blood and provide tension/ counter tension and exposure. Prof. S. Subbiah et al
  • 22. • The average set-up time after preliminary experience for TORS is about 30 minutes or less. Prof. S. Subbiah et al
  • 25. TONGUE BASE • Early lesion involving base of tongue (T1/T2) • Transoral robotic base of tongue resection has been found to be useful in a diagnostic capacity in the setting of unknown primary head and neck malignancy. • The angled scopes improves visualization and helps the surgeon to navigate around corners, as is often needed in tongue base surgery Prof. S. Subbiah et al
  • 26. TONGUE BASE STEP 1 : Anterior mucosal incision - jus behind the retractor , not more than 1 cm depth STEP 2 : Medial incision -Anterior to posterior till the vallecula is reached. STEP 3 : Lateral incision -proceed from lateral to medial .Continue the mucosal incision across the glossotonsillar sulcus then along the lateral pharyngeal wall up to the vallecula Prof. S. Subbiah et al
  • 27. • STEP 4 : Vallecular dissection • STEP 5 : Specimen orientation and frozen for margins • STEP 6 :Hemostasis. Prof. S. Subbiah et al
  • 28. TONSILLAR AREA • Studies have shown that surgery is highly effective in treating tonsillar cancer and provides accurate staging information for adjuvant therapy. Prof. S. Subbiah et al
  • 29. • Weinstein et al. described TORS for radical tonsillectomy in 27 patients with invasive squamous cell carcinoma of the tonsil. Prof. S. Subbiah et al
  • 30. • Unresectable neck nodes • Mandibular invasion, • Involvement of >50% of the tongue base, • Involvement of >50% of the posterior pharyngeal wall, • Carotid artery involvement. • Fixation to prevertebral fascia. Prof. S. Subbiah et al
  • 31. TORS SUPRAGLOTTIC LARYNGECTOMY 1) Patients with adequate transoral exposure of the surgical field; 2) T1 or T2 supraglottic carcinoma; 3) Selected T3 supraglottic carcinoma with mobile vocal cords (with or without preepiglottic space invasion); and 4) tumors with minimal pyriform sinus involvement. Prof. S. Subbiah et al
  • 32. CONTRAINDICATIONS • 1) Limited transoral exposure (ie, trismus, macroglossia, micrognathia, or retrognathia); • 2) Poor pulmonary reserve (FEV1/FVC <50%); • 3) Tumor involvement of the thyroid cartilage or anterior commissure; • 4) Vocal cord fixation or paraglottic space invasion; • 5) Bilateral arytenoid cartilage involvement; • 6) Tumor extension into pyriform apex or postcricoid mucosa. Prof. S. Subbiah et al
  • 34. TORT ( TRANS ORAL ROBOTIC THYROIDECTOMY) • In 2009, Benhidjeb et al. reported the first series of transoral thyroidectomy. • The central camera was passed through a sublingual incision. • The two lateral working arms passed through vestibular incisions anterior to the mandible. Prof. S. Subbiah et al
  • 35. TOR/ETVA In 2011, Richmon et al. modified this approach to avoid the floor of mouth route. All three ports were placed through the vestibule anterior to the mandible to access the subplatysmal space and the floor of mouth was not violated. Prof. S. Subbiah et al
  • 37. OTHERS • Infratemporal fossa Resection • Robotic-assisted microvascular anastomosis • First two cases of TORS-assisted free flap (radial forearm) reconstruction carried out successfully . Prof. S. Subbiah et al
  • 38. NECK • Positive neck nodes • Patients with high risk (≥20%) for occult nodal involvement. • Neck dissections (uni- or bilateral) can be performed immediately before or after the TORS procedure or as a second-stage procedure. Prof. S. Subbiah et al
  • 39. SHIFT OF PARADIGM Prof. S. Subbiah et al
  • 40. • Cracchiolo et al discovered a steep rise of patients with low T-status (T1–T2) OPSCC who underwent primary surgical treatment. • Total cases 3071 • TORS 846 (27.6%) • In 2010 137 patients were treated with TORS, • In 2013 280 patients were treated with TORS. Prof. S. Subbiah et al
  • 41. ABSOLUTE CONTRAINDICATION • Reduced mouth opening. • Incomplete lesion visualisation. • Mandible involvement. • Tumours involving >50% of the base of the tongue. • Internal carotid artery, or prevertebral fascia involvement. Prof. S. Subbiah et al
  • 42. BENEFITS • Primary TORS- possible alternative to non-surgical organ preservation regimen • Up-front TORS - deintensification of adjuvant therapy. • Patients who would have received definitive RT as a single modality treatment could avoid it with primary TORS and possible complications of radiation therapy . Prof. S. Subbiah et al
  • 43. • swallowing outcomes • More et al. compared functional swallowing out-comes after TORS with outcomes after primary chemoradiation therapy tonsillar cancer. They found significantly better scores of the MD Anderson Dysphagia Inventory (MDADI) at 6 and 12 months postoperatively for those patients who underwent TORS. Prof. S. Subbiah et al
  • 44. • 10x magnification results in improved visualisation and the ability to resect lesions en bloc in the oropharynx. • Biology of disease and exact pathological report can be obtained. • TORS may avoid disfiguring surgeries. Prof. S. Subbiah et al
  • 45. • Recent studies found out that surgical staging alters clinical staging in 40% after TORS • The robotic arms also filter tremors, allowing precision with microscopic movements. Prof. S. Subbiah et al
  • 47. ONCOLOGICAL OUTCOMES Meta analysis. Compared primary TORS with Open surgery. TORS showed lower mortality rate , recurrence rate and positive margin rates compared with open surgery. But no significant statistical difference between two groups. Disease-free survival rate was significantly higher in the TORS group than open surgery group. Prof. S. Subbiah et al
  • 48. FUNCTIONAL OUTCOMES • Park et al. evaluated prospectively the functional outcomes of patients treated with TORS in comparison with patients treated conventionally with transoral approach or mandibulotomy during the same period of the study. • There was a significant difference in swallowing, time to decannulation, and hospitalization period between the two groups. • In the TORS group, patients completely recovered the ability to swallow after 6 days. In contrast, patients undergoing conventional surgery did not completely recover their swallowing until 12 days. Prof. S. Subbiah et al
  • 49. DISADVANTAGES • Ruptures during TORS are not unusual due to manipulation by the Maryland forceps and could be misinterpreted by the pathologist as being a compromised margin. • Cost effectiveness. • Long learning curve. Prof. S. Subbiah et al
  • 50. COMPLICATIONS • Hemorrhage • Hematoma • Wound infection • Nerve palsy • Aspiration related infection • Rarely fistula. • complication rates are much less compared to open surgery or radiation therapy. Prof. S. Subbiah et al
  • 51. Debatable • For comparing TORS with chemoradiation in terms of overall survival and disease free interval we need more RCT and worldwide adoption of TORS Prof. S. Subbiah et al
  • 52. RECENT There are two techniques that are likely to improve margin control in TORS, Intelligent Knife technology. Narrow band imaging Intra-Operative Fluorescence Imaging. Prof. S. Subbiah et al
  • 53. THANK YOU Prof. S. Subbiah et al