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Anti-Microbial
For the Health of your Community

Multi-Family 2014
Email: Chris.Beckman@WilkinsSolutions.com / Skype: c.beckman1
LinkedIn: http://www.linkedin.com/pub/chris-beckman/3b/799/907/
Twitter: @SeeBeckman
HTTP://www.WilkinsSolutions.com
HTTP://www.facebook.com/WilkinsSolutionsTennessee

Chris Beckman
Nashville, TN / (615) 669-FIT1 (3481)
“Tennessee based Sales, Service and Accountability”
Providing Affordable, Environmentally
Safe, “GREEN”, Non-Toxic Antimicrobial
Smart Coatings and Long-Lasting Hand
& Clothing Sanitation Options

Leading Edge Preventative Germ & Bacteria Solutions for:

Multi-Family Housing
Topic Agenda
Affiliations & Resources
Infection Prevention (4 Layers)
Layer by Layer Recomendations
Surface Options Detail

Long Term Durability and
Ancillary Benefits
How the Products are Applied & Tested
More Resources
Affiliations & Resources

Surface Recontamination Shield

(SRS) Certifier

Healing Hands are Clean Hands

A Quiet Battle

S.I.C.K. Team
It’s Delivery System
NEW Technology Enables this Anti-Microbial
to be applied via a Electro Static System
that is TRULY Remarkable

NANO Technology

Mark Shaw ‘s Demonstration at
TED Forum in Long Beach CA
February 2013
http://www.youtube.com/watch?v=pn0J05v1Jzk
WARNING: This Video my inspire thoughts of the
multitude of ways this product can be used…
4 Infection Prevention Layers
1.
2.
3.
4.

Hand Sanitization / Continuous Protection
Clothing Disinfection / Protection
Surface Cleaning / Disinfection
Surface Continuous Protection
o Antifouling and anti-adhesive coatings
o Zwitterionic polymer biomimetic surfaces
o Antimicrobial coatings and surface
technologies
CLEANING PROTOCOLS
• Antimicrobials are designed to enhance
cleaning protocols not replace them.
• The technology allows for protection between
cleanings.
• Environmentally safe providing a ―GREEN‖
application and removing the need for
chemical cleaning. (soap and water)
• Cost effective, reduces the need to buy
expensive chemicals and decreased cleaning
time for staff (as much as 66%).
Hand Sanitization / Protection
Why not Alcohol Based?
Hand Sanitization / Protection
•

Seek an Alcohol-free sanitizer safe for your hands
and effective in providing you, employees, and
customers proactive security from germs that can
make you sick.
• Look for one that when applied creates a hydrogen
bond to skin cells where applied. This bond locks the
protection to the skin cell until its natural shed period of
24-60 hours is reached. (or until the skin cells have
been shed through excessive hand washings. i.e. 10
washings)
Hand Sanitization / Protection
Not all Non-Alcohol based sanitizers are
the same…
The Active Ingredient in many other Non-Alcohol
based sanitizers is Triclosan which is rated as a
level 7 high hazard in the Safety Database
Triclosan has been shown to accumulate biosolids in the
environment, one of the top seven organic contaminants in
waste water according to the National Toxicology Program.
Triclosan leads to various problems with natural biological
systems. Triclosan, when combined with chlorine e.g. from
tap water, produces dioxins, a probable carcinogen in
humans.
Triclosan is currently under review by the FDA due to
possible health hazards.
Why switch?
• In today's world, its about cost effective protection, to keep
everyone healthy. With budgets deciding how many employees it
takes to perform a job, being healthy and able to work is more
important then ever. The health risks that face educational staff
is greater then ever.
• This is the most cutting edge technology in personal health
protection….be it in a school, a fitness gym, an office, anywhere.

1. NON-TOXIC if swallowed, does not require poison
control reporting.
2. NON-FLAMMABLE does not pose a safety risk
3. LONGEST LASTING sanitizer on the market
4. NON-DRYING of the skin, promotes healthy skin care
5. MOST COST EFFECTIVE alternative available
4 Infection Prevention Layers
1.
2.
3.
4.

Hand Sanitization / Continuous Protection
Clothing Disinfection / Protection
Surface Cleaning / Disinfection
Surface Continuous Protection
o Antifouling and anti-adhesive coatings
o Zwitterionic polymer biomimetic surfaces
o Antimicrobial coatings and surface
technologies
Clothing Disinfection/Protection
•

Similar technology can be easily applied through the wash, as a
side benefit it continually and proactively prevents odor, staining
and deterioration.

•

Application must be done separately from normal washing. Do
not mix with regular detergent or bleach. New model washing
machines have the capacity to integrate solutions.

•

Invisible, hypoallergenic and non-toxic antimicrobial coating on
fabrics that laundry detergents just can’t offer.

•

Will not create adaptive organisms or “super bugs”.
Small Sample of Protection List
Organisms: Bacillus sp (vegetative cell), Corynebacterium diptheriae, Micrococcus
lutea, Micrococcus sp., Mycobacterium tuberculosis, Mycobacterium smegmatis,
Propionbacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis,
Streptococcus faecalis, Streptococcus mutans, Streptococcus pneumonia,

Streptococcus pyogenes, Acinetobacter calcoaceticus, Aeromanas hydrophilia,
Citrobacter deversus, Citrobacterfreundi, Enterobacter aerogenes, Enterobacter
aglomerans, Enterbacter cloacae, Enterococcus, Escherichia coli, Klebsiella oxytoca,
Klebsiella pneumoniae, Klebsiella terrienca, Legionella pneumophila, Mrganella
morganii, Proteus mirabilis, Proteus vulgaris, Pseudomanas aeruginosa.
Germs: Pseudomonas fluorscens, Salmonella cholera suis, Salmonella typhimurium,
Serratia liguifaciens, Serratia marcescens, Xanthomonas campestris.
Viruses: Adenovirus Type II & IV, Bovine Adenovirus Type I & IV, Feline pneumonitis,
Herpes Simplex Type I. Herpes Simplex Type II, HIV-1 (AIDS), Influenza A2 (Aichi),
Influenza A2 (Asian), Influenza B, Mumps, Parinfluenza (Sendai), Rous Sarcoma,
reovirus Type I, Dimian Virus, Vaccinia.
Clothing Disinfection/Protection
• Creates an environmentally-friendly, non-toxic and
hypoallergenic antimicrobial barrier on fabrics.
• Continually fights the growth of fabric bacteria,
fungi and mold on washable fabrics.
• High-performance, non-leaching antimicrobial
characteristics allow for proactive and constant
prevention of odor, staining, and deterioration.
• One application lasts 90 days.
• Invisible and odorless, should not affect the
appearance of fabrics
4 Infection Prevention Layers
1.
2.
3.
4.

Hand Sanitization / Continuous Protection
Clothing Disinfection / Protection
Surface Cleaning / Disinfection
Surface Continuous Protection
o Antifouling and anti-adhesive coatings
o Zwitterionic polymer biomimetic surfaces
o Antimicrobial coatings and surface
technologies
Surface Cleaning / Disinfection
Should be used prior to the application of long-lasting
antimicrobial products. Use a hospital-grade cleaner
disinfectant that kills at least 99.9999% of germs and
bacteria on surfaces.
Pre-cleaning enhances the effectiveness of
antimicrobial coatings by properly preparing surfaces
for antimicrobial treatment.
•
•
•
•

OSHA blood borne pathogen standard for HIV, HBV and HCV.
Tuberculocidal
Virucidal
Mildewstat / Fungicidal

It is also recommended for regular maintenance cleaning.
Surface Cleaning / Disinfection
• Disinfectant cleaner, at a minimum,
should be effective against these
commonly known illness-causing
microorganisms across three categories:

1. Antibiotic-Resistant Bactericidal Activity
2. Bactericidal Activity
3. Virucidal Activity
Surface Cleaning / Disinfection
Antibiotic-Resistant Bactericidal Activity:
Community Associated Methicillin Resistant Staphylococcus aureus (CA-MRSA) (NRS 123)
Genotype USA 400 (NRS384) Genotype USA 300, Methicillin resistant staphylococcus
aureus (MRSA), (ATCC 33593), Vancomycin resistant Enterococcus faecalis (VRE),
(ATCC 51575), Vancomycin intermediate resistant Staphylococcus aureus (VISA), (CDC
Isolate 99287), Methicillin resistant Staphylococcus epidermidis (MRSE), (ATCC 51625)

Bactericidal Activity:
Staphylococcus aureus, (ATCC 6538), Pseudomonas aeruginosa, (ATCC 15442), Salmonella
choleraesuis, (ATCC 10708), Escherichia coli, (ATCC 11229), Escherichia coli O157:H7,
(ATCC 43895), Listeria monocytogenes, (ATCC 35152), Salmonella typhi, (ATCC 6539),
Streptococcus pyogenes (Necrotizing Fasciitis-Group A) (V.A. Medical Center Isolate
04001), Yersinia enterocolitica, (ATCC 23715), Enterococcus francium, (ATCC 6569),
Corynebacterium ammoniagenes, (ATCC 6871)

Virucidal Activity:
Avian Influenza A Virus (H3N2), (Avian Reassortant) (ATCC VR-2072), Avian Influenza Virus
Type A (Turkey/WIS/66), (H9N2), SARS Associated Corona virus (ZeptoMetrix),
Paramyxovirus (Mumps) (ATCC VR-1438), Hepatitis A Virus (HAV), Rhinovirus Type 39
(ATCC VR-340), Rotavirus
Disinfectants are Temporary!
Surface Recontamination
can occur immediately after
a thorough cleaning.
Some Disinfectants even is the residual kill time of
What
require a “dwell time” to disinfectants?
most
reach the log reduction
advertised.
4 Infection Prevention Layers
1.
2.
3.
4.

Hand Sanitization / Continuous Protection
Clothing Disinfection / Protection
Surface Cleaning / Disinfection
Surface Continuous Protection
o Antifouling and anti-adhesive coatings
o Zwitterionic polymer biomimetic surfaces
o Antimicrobial coatings and surface
technologies
Surface Continuous Protection
• Historical Evolution
o Antifouling and anti-adhesive coatings
o Zwitterionic polymer biomimetic
surfaces (both positive & negative
charged molecules)
o Antimicrobial coatings and surface
technologies
DID
YOU
KNOW?

Americans
touch an
average of
300
infected
surfaces
every 30
minutes.

One cell of
staph can
multiply
into 17
million in
just 48
hours.

A Study conducted at the
University of Arizona found
that the most germ-infected
objects were:
1. Cell phones
2. Desktops
3. Water fountain handles
4. Computer keyboards
5. Computer mice
Common practices for reducing the
exposure to pathogens on surfaces?
•

“Perceived Cleanliness”

•

Spot Cleaning when visible fluid or
dirt appears

•

Temporarily Disinfecting the
surfaces based on protocol
What is the residual kill time of
most disinfectants?
Toxic Shields – frequently reapplied

•
4 Infection Prevention Layers
1.
2.
3.
4.

Hand Sanitization / Continuous Protection
Clothing Disinfection / Protection
Surface Cleaning / Disinfection
Surface Continuous Protection
o Antifouling and anti-adhesive coatings
o Zwitterionic polymer biomimetic surfaces
o Antimicrobial coatings and surface
technologies
Antifouling and anti-adhesive
surface coatings
•
•
•
•

Poly(ethylene glycol) coatings (PEG)
Self-Assembled Monolayer (SAM)
Diamond-like carbon (DLC) films
Easy clean surfaces
•
•

Pilkington Active <10 degrees contact angle
Pilkington Hydrotech >130 degrees contact angle

• BUT: It merely moves them elsewhere,
where they will have to be dealt with by
other microbicidal techniques.
Zwitterionic polymer
biomimetic surfaces
• Mimic properties found in the lipid bilayers of
biological membranes
• Zwitterionic surfaces are biocompatible and
non-thrombogenic discouraging adhesion of
cells, both mammalian and microbial

• BUT: Still do not fully address the problem of
microbial contamination as they have no
antimicrobial functionality.
Antimicrobial coatings and
surface technologies
The 6 core technologies are:
1.
2.
3.
4.
5.
6.

Microbicide-releasing surfaces
Silver and silver-containing surfaces
Copper and copper alloy surfaces
Bacteriophage-modified surfaces
Polycationic antimicrobial surfaces
Light Activated Antimicrobial Agents (LAAAs)
1. Microbicide-releasing
surfaces
• The most well known is Microban
• Microban incorporates Triclosan (chlorodichlorophenoxy-phenol) a broad spectrum
phenolic antimicrobial.
• BUT: It is only active against Bacteria, not
virus, spores, or Volitile Organic Compounds
(VOCs). It is toxic in aquatic systems and is an
endocrine disruptor. Most concerning is that it
degrades to Dioxin which is extremely
hazardous to man.
2. Silver and
silver-containing surfaces
• To date, few organisms have developed
resistance towards the silver ion as an
antimicrobial.
• BUT besides ―expense‖ there are a couple of
drawbacks:
1. They are non-permanent (leaching), relying
on diffusible antimicrobials to which microbes
can develop resistance.
2. Possible Ag ion cytotoxicity towards
mammalian cells
3. Copper and
copper alloy surfaces
• Brass is less effective than pure copper but
still exhibits antimicrobial activity
• Alloys have improved aesthetic and
mechanical properties and may be more
suited to real world applications
• Door plates, handles and other surfaces could
employ copper alloys, but it’s a relatively
expensive solution
4. Bacteriophage-modified
surfaces
• Bacteriophages are viruses that infect
prokaryotic cells.
• Phages usually target individual species of
bacteria, bind to their surface, inject their
genetic material and replicate within the
bacterial host.
• BUT they are not practical in general settings
where specific targets may not be few enough
and viruses, spores etc. are not addressed at
all. Also of concern is Phage resistant strains.
5. Polyatomic Antimicrobial Surfaces
• Polyethyleneimines (PEIs)
• A positively charged moiety is required—this
keeps the hydrophobic chains separated and
erect from the surface, and also
electrostatically attracts microbes, due to the
net negative charge on their surface.
• BUT, their mechanical stability and longevity
have not been described and it is still yet to be
seen how well they might respond to the rigors
of use and indeed cleaning in a clinical setting.
6. Light Activated Antimicrobial
Agents (LAAAs)
• Photosensitiser (PDT Refinement)
•

PDT is a form of indirect phototherapy, in which light
is used as a means of activating the curative agent.

• Titanium Dioxide Photocatalysis
•
•
•

•

(Effective with UV or visible spectrum though doping.
eg. With Nitrogen or Tungsten oxide)
Shown to be benign to the environment and humans,
animals, birds, and aquatic systems. (No Toxicity)
Highest binding, permanent, unless removed through
abrasion
Active against: Bacteria, Viruses, Spores (i.e. mold,
mildew), VOCs and odors!
WSE Available Alternatives

Manufacturers

Applicators

•
•
•
•

Silver: Agion
Triclosan : Microban
Quanternary Ammonium: Aegis
Photocatalyst: EcoActive

What is the residual kill time of
most disinfectants?
• Bio Protect
• Coating Specialist
• SRS (OxiTitan)
Antimicrobial Surface Coatings Comparison
Coating Class

Surface Photocatalyst

Quaternary Ammonium

Silver

Triclosan

Active Component(s)
Mode of Action
Effective Against:
Bacteria
Viruses

Zinc, Titanium Dioxide
Contact Photo-Oxidation

Ammonium Chloride
Silver Ions
Phenoxy Phenols (PCPP)
Contact Dilute Chloride Salts Leaching Heavy Metal in H2O Leaching Poison

Active Bactericide
Active Virucide

Spores
VOCs
Odors
Toxicity Risks To:
Humans
Animals & Birds
Aquatic Systems

Active Sporicide
All
All

Bacteriostatic
Ineffective Against Nonenveloped Viruses
Fungistatic
No
Bacterial only

No
No
No

High Toxicity to Skin and Eyes
High Toxicity to Skin and Eyes
High Toxic, Zero Discharge
Allowed
Environmental Fate Risk
None
5-Year Degradation Time
Resistant Bacteria Promotion No
No
UV Damage Protection
95%
No
Metal Corrosion Protection Yes
Corrosive
Hydrophilic Self-Cleaning
Yes
No
Application Method
Water based spray
Spray
Treatable Surfaces
All Substrates and Textiles Hard Surface or Textile
New or Existing
Durability
Very High Binding
Removed by Surfactants
(Detergents or Soap)
Service Interval
6 mo. - 3 Years
1-3 months unless cleaned
Regulatory Guidance
US EPA FIFRA 25B
US EPA FIFRA
Minimum Risk Pesticide
Registered
Exempt From Registration

Bactericide
Virucide

Bactericide
No

Sporicide
No
Bacterial Only

No
No
Bacterial Only

Bio-Accumulative
Bio-Accumulative
Highly Toxic,
Bio-Accumulative
Very High
Yes
No
No
No
Epoxy Paint
Paintable

Endocrine Disruptor
Endocrine Disruptor
Toxic

Incorporated

Incorporated at Manufacture

Repaint
US EPA Registered
Currently Restricted for
Review

Item Replacement
US EPA Registered
Under Regulatory Review
EU banned

Degrades to Dioxin
Yes
No
No
No
Incorporated at Manufacture
Incorporated at Manufacture
The best combinative surface
solution available
Surface Recontamination Shield (SRS)
A Professionally applied antimicrobial
smart coating for continuous protection
against bacteria, viruses, mold and
fungi for a cleaner, healthier
environment.
What is the residual kill time of
most disinfectants?
This coating is an energetic trap for
microbes and Volatile Organic
Compounds (VOCs) at a molecular
level, completing their destruction
through photocatalytic oxidation (PCO).
US Independent Lab Testing
The tests were designed to determine the efficacy of the antimicrobial
coatings in the most adverse conditions by giving the bacteria the optimal
growth environment.
ALL LAB TESTS USED ONLY TYPICAL ARTIFICIAL ROOM LIGHTING. The presence
of natural light or greater artificial lighting will increase the efficacy of the
coating in bacterial, virus and VOC reduction.

What is the residual kill time of
Tests by leading US laboratories show strong, persistent and protective
most disinfectants?

cleaning power in real world conditions: 98% reduction of deadly VRE
bacteria in 15 minutes; prolonged virus reduction of 89% over 24 hours and
strong reductions of MRSA and Staph; 91% reduction of C. difficile spores
over 24 hours and 99% reduction of hydrogen sulfide over 24 hours.
SRS’s Multiple Attributes
• Antimicrobial---Continuously kill all microbes contacting the
surface

• Superhydrophilic---Clean the surface continuously
• 95% UV Protection---Protects any surface from sun damage

What is the residual kill time of
most disinfectants?

• Anti-Corrosive---Protect metals against corrosion

• VOC Elimination---Destroys Pollutants and Odors
• Lowest Comprehensive Cost - Economically Effective
Antimicrobial
SRS deactivates ALL dangerous microbes and
restrains proliferation by damaging their
components through radical oxidation.
This broad spectrum photo-mineralization of
pathogens is continuous and permanent.
Does not cause resistant strains of microbes
becauseWhat is the residual kill time of
its killing mechanism is strictly
oxidative, not disinfectants?
most enzymic or antibiotic.
Antimicrobial coatings are protectants not
disinfectants…they work in between
cleanings.
SRS is Superhydrophilic

What is the residual kill time of
most disinfectants?
Self-Cleaning

What is the residual kill time of
most disinfectants?
SRS’s UV Protection
• The damaging rays
of Ultraviolet (UV)
light cause billions
of dollars of damage
to paints, plastics
and textiles exposed What is the residual kill time of
most disinfectants?
to sunlight.
• The SRS works as
sunscreen on
surfaces
Oxy-Titan is Anti-Corrosive

What is the residual kill time of
most disinfectants?
VOC & Odor Reduction
 SRS removes odors and
breaks down dangerous
VOCs and pollutants in
the air.

 This safe, persistent
cleansing of the air
occurs using both natural
sunlight and, most
importantly, visible light
indoors.?
SRS….How long will it last?
 The coating can only be
removed by taking part of
the substrate off through
high friction polishing or
abrasions.
 One treatment will last up
to 1 year.

What is the residual kill time of
most disinfectants? surface is dry the
 Once the
coating becomes one with
the substrate and cannot
be removed without
removing the substrate
SRS….How to prove
the product is still working
PCO™

Verification Ink

• A quick and easy visible quality check!
• Safe, water soluble, reaction dye
• The ink will changeWhat is the minutes or less
in a few residual kill time of
from blue to pink most disinfectants?
• Color change is proof that the SRS is protecting
the surface, killing bacteria and viruses and
breaking down VOCs (the odor reduction is self evident)
Messaging for your facility…
Display the SAFE STAMP in your facilities to instantly communicate that
additional precautions have been taken to ensure a healthy environment.

What is the residual kill time of
most disinfectants?
How the SRS is applied
Original
Sphere

Electrostatics

OFF

Electrostatics
ON

 Professional Electrostatic
Spray System
 Ensures efficacy of
coverage
 70 Times more coverage
than conventional
What is the residual kill time of
sprayers.
most disinfectants?
 Treated surface dries in
less than 30 seconds
 40 Times greater
than the force of gravity
Click pictures to view Videos

Training and
Assisted Living Facility
Project Example

Electrostatic Spraying

Diamond Building
Electrostatic Spraying

What is Electrostatic Spraying?
Application Methods
Self Application: 800 sq/ft per gallon.
HVLP Application: 1200-1500 sq/ft per gallon
ESS Application: 3300-3600 sq/ft per gallon
Due to the droplet size each application
process administers, the amount of coverage
has considerable cost variance and volume of
product use.
Comparative Cost for ESS
Protection
• Triclosan (MicroBan) – EU Banned and under
Regulatory Review in the U.S.
• Silver (Agion, HeiQ) > $1.50/sq. ft. (plus
application fee)
• Quaternary Ammonium (Aegis, and 45 other
registrants) Highly Toxic to skin and eyes and
all aquatic systems [zero discharge allowed]
> 2 cents/sq. ft. (plus application fee)
• Surface Photocatalyst (EcoActive and several
private labels) < 5 cents/sq. ft. (plus
application fee)
How we do a Project
• Determine the IC
needs including
persons surfaces and
areas to be treated.
• Assess hand, clothing
and surface usage. What is the residual kill time of
• Measure SQFT of most disinfectants?
footprint, walls,
equipment, counters,
desks, and other
surfaces.
More Information on
Selecting Antimicrobials:
Household Cleaning - University of Nebraska- Lincoln
Selecting an Appropriate Sanitizer or Disinfectant National Resource Center for Health and Safety in Child
Care and Early Education
Cleaning Up Antimicrobial Hand Soaps - Johns Hopkins
School of Public Health
Disinfection and Remediation Guidelines for Pools and
Spas - Centers for Disease Control and Prevention
Healthy Swimming - Centers for Disease Control and
Prevention
Cleaning, Sanitizing, and Disinfecting in Child Care
Settings - National Resource Center for Health and Safety
in Child Care and Early Education
Surfaces and antimicrobial surface
coatings in the epidemiology of HAIs

*Hospital Acquired Infections - HAIs)
1. Hospital Grade Cleansing/Disinfectant
2. Non-Alcohol Based Hand Sanitizer/Protectant
3. Disinfection/Antimicrobial Clothing Protection
4. Continuous Antimicrobial Surface Protection
Solution
Analysis &
Design

Negotiation &
Procurement
Service

Installation
Accountability

For More INFORMATION in how OXYTITAN can be of benefit to your Community
Chris.Beckman@WilkinsSolutions.com / 888-460-4050 / www.wilkinssolutions.com
Chris.Beckman@WilkinsSolutions.com
615-669-3481
www.wilkinssolutions.com
www.facebook/WilkinsSolutionsTennessee

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Anti-Microbial allows for a Healthier Community & and many more benefits!!

  • 1. Anti-Microbial For the Health of your Community Multi-Family 2014 Email: Chris.Beckman@WilkinsSolutions.com / Skype: c.beckman1 LinkedIn: http://www.linkedin.com/pub/chris-beckman/3b/799/907/ Twitter: @SeeBeckman HTTP://www.WilkinsSolutions.com HTTP://www.facebook.com/WilkinsSolutionsTennessee Chris Beckman Nashville, TN / (615) 669-FIT1 (3481) “Tennessee based Sales, Service and Accountability”
  • 2. Providing Affordable, Environmentally Safe, “GREEN”, Non-Toxic Antimicrobial Smart Coatings and Long-Lasting Hand & Clothing Sanitation Options Leading Edge Preventative Germ & Bacteria Solutions for: Multi-Family Housing
  • 3. Topic Agenda Affiliations & Resources Infection Prevention (4 Layers) Layer by Layer Recomendations Surface Options Detail Long Term Durability and Ancillary Benefits How the Products are Applied & Tested More Resources
  • 4. Affiliations & Resources Surface Recontamination Shield (SRS) Certifier Healing Hands are Clean Hands A Quiet Battle S.I.C.K. Team
  • 5. It’s Delivery System NEW Technology Enables this Anti-Microbial to be applied via a Electro Static System that is TRULY Remarkable NANO Technology Mark Shaw ‘s Demonstration at TED Forum in Long Beach CA February 2013 http://www.youtube.com/watch?v=pn0J05v1Jzk WARNING: This Video my inspire thoughts of the multitude of ways this product can be used…
  • 6. 4 Infection Prevention Layers 1. 2. 3. 4. Hand Sanitization / Continuous Protection Clothing Disinfection / Protection Surface Cleaning / Disinfection Surface Continuous Protection o Antifouling and anti-adhesive coatings o Zwitterionic polymer biomimetic surfaces o Antimicrobial coatings and surface technologies
  • 7. CLEANING PROTOCOLS • Antimicrobials are designed to enhance cleaning protocols not replace them. • The technology allows for protection between cleanings. • Environmentally safe providing a ―GREEN‖ application and removing the need for chemical cleaning. (soap and water) • Cost effective, reduces the need to buy expensive chemicals and decreased cleaning time for staff (as much as 66%).
  • 8. Hand Sanitization / Protection
  • 10. Hand Sanitization / Protection • Seek an Alcohol-free sanitizer safe for your hands and effective in providing you, employees, and customers proactive security from germs that can make you sick. • Look for one that when applied creates a hydrogen bond to skin cells where applied. This bond locks the protection to the skin cell until its natural shed period of 24-60 hours is reached. (or until the skin cells have been shed through excessive hand washings. i.e. 10 washings)
  • 11. Hand Sanitization / Protection
  • 12. Not all Non-Alcohol based sanitizers are the same… The Active Ingredient in many other Non-Alcohol based sanitizers is Triclosan which is rated as a level 7 high hazard in the Safety Database Triclosan has been shown to accumulate biosolids in the environment, one of the top seven organic contaminants in waste water according to the National Toxicology Program. Triclosan leads to various problems with natural biological systems. Triclosan, when combined with chlorine e.g. from tap water, produces dioxins, a probable carcinogen in humans. Triclosan is currently under review by the FDA due to possible health hazards.
  • 13. Why switch? • In today's world, its about cost effective protection, to keep everyone healthy. With budgets deciding how many employees it takes to perform a job, being healthy and able to work is more important then ever. The health risks that face educational staff is greater then ever. • This is the most cutting edge technology in personal health protection….be it in a school, a fitness gym, an office, anywhere. 1. NON-TOXIC if swallowed, does not require poison control reporting. 2. NON-FLAMMABLE does not pose a safety risk 3. LONGEST LASTING sanitizer on the market 4. NON-DRYING of the skin, promotes healthy skin care 5. MOST COST EFFECTIVE alternative available
  • 14. 4 Infection Prevention Layers 1. 2. 3. 4. Hand Sanitization / Continuous Protection Clothing Disinfection / Protection Surface Cleaning / Disinfection Surface Continuous Protection o Antifouling and anti-adhesive coatings o Zwitterionic polymer biomimetic surfaces o Antimicrobial coatings and surface technologies
  • 15. Clothing Disinfection/Protection • Similar technology can be easily applied through the wash, as a side benefit it continually and proactively prevents odor, staining and deterioration. • Application must be done separately from normal washing. Do not mix with regular detergent or bleach. New model washing machines have the capacity to integrate solutions. • Invisible, hypoallergenic and non-toxic antimicrobial coating on fabrics that laundry detergents just can’t offer. • Will not create adaptive organisms or “super bugs”.
  • 16. Small Sample of Protection List Organisms: Bacillus sp (vegetative cell), Corynebacterium diptheriae, Micrococcus lutea, Micrococcus sp., Mycobacterium tuberculosis, Mycobacterium smegmatis, Propionbacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus faecalis, Streptococcus mutans, Streptococcus pneumonia, Streptococcus pyogenes, Acinetobacter calcoaceticus, Aeromanas hydrophilia, Citrobacter deversus, Citrobacterfreundi, Enterobacter aerogenes, Enterobacter aglomerans, Enterbacter cloacae, Enterococcus, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Klebsiella terrienca, Legionella pneumophila, Mrganella morganii, Proteus mirabilis, Proteus vulgaris, Pseudomanas aeruginosa. Germs: Pseudomonas fluorscens, Salmonella cholera suis, Salmonella typhimurium, Serratia liguifaciens, Serratia marcescens, Xanthomonas campestris. Viruses: Adenovirus Type II & IV, Bovine Adenovirus Type I & IV, Feline pneumonitis, Herpes Simplex Type I. Herpes Simplex Type II, HIV-1 (AIDS), Influenza A2 (Aichi), Influenza A2 (Asian), Influenza B, Mumps, Parinfluenza (Sendai), Rous Sarcoma, reovirus Type I, Dimian Virus, Vaccinia.
  • 17. Clothing Disinfection/Protection • Creates an environmentally-friendly, non-toxic and hypoallergenic antimicrobial barrier on fabrics. • Continually fights the growth of fabric bacteria, fungi and mold on washable fabrics. • High-performance, non-leaching antimicrobial characteristics allow for proactive and constant prevention of odor, staining, and deterioration. • One application lasts 90 days. • Invisible and odorless, should not affect the appearance of fabrics
  • 18. 4 Infection Prevention Layers 1. 2. 3. 4. Hand Sanitization / Continuous Protection Clothing Disinfection / Protection Surface Cleaning / Disinfection Surface Continuous Protection o Antifouling and anti-adhesive coatings o Zwitterionic polymer biomimetic surfaces o Antimicrobial coatings and surface technologies
  • 19. Surface Cleaning / Disinfection Should be used prior to the application of long-lasting antimicrobial products. Use a hospital-grade cleaner disinfectant that kills at least 99.9999% of germs and bacteria on surfaces. Pre-cleaning enhances the effectiveness of antimicrobial coatings by properly preparing surfaces for antimicrobial treatment. • • • • OSHA blood borne pathogen standard for HIV, HBV and HCV. Tuberculocidal Virucidal Mildewstat / Fungicidal It is also recommended for regular maintenance cleaning.
  • 20. Surface Cleaning / Disinfection • Disinfectant cleaner, at a minimum, should be effective against these commonly known illness-causing microorganisms across three categories: 1. Antibiotic-Resistant Bactericidal Activity 2. Bactericidal Activity 3. Virucidal Activity
  • 21. Surface Cleaning / Disinfection Antibiotic-Resistant Bactericidal Activity: Community Associated Methicillin Resistant Staphylococcus aureus (CA-MRSA) (NRS 123) Genotype USA 400 (NRS384) Genotype USA 300, Methicillin resistant staphylococcus aureus (MRSA), (ATCC 33593), Vancomycin resistant Enterococcus faecalis (VRE), (ATCC 51575), Vancomycin intermediate resistant Staphylococcus aureus (VISA), (CDC Isolate 99287), Methicillin resistant Staphylococcus epidermidis (MRSE), (ATCC 51625) Bactericidal Activity: Staphylococcus aureus, (ATCC 6538), Pseudomonas aeruginosa, (ATCC 15442), Salmonella choleraesuis, (ATCC 10708), Escherichia coli, (ATCC 11229), Escherichia coli O157:H7, (ATCC 43895), Listeria monocytogenes, (ATCC 35152), Salmonella typhi, (ATCC 6539), Streptococcus pyogenes (Necrotizing Fasciitis-Group A) (V.A. Medical Center Isolate 04001), Yersinia enterocolitica, (ATCC 23715), Enterococcus francium, (ATCC 6569), Corynebacterium ammoniagenes, (ATCC 6871) Virucidal Activity: Avian Influenza A Virus (H3N2), (Avian Reassortant) (ATCC VR-2072), Avian Influenza Virus Type A (Turkey/WIS/66), (H9N2), SARS Associated Corona virus (ZeptoMetrix), Paramyxovirus (Mumps) (ATCC VR-1438), Hepatitis A Virus (HAV), Rhinovirus Type 39 (ATCC VR-340), Rotavirus
  • 22. Disinfectants are Temporary! Surface Recontamination can occur immediately after a thorough cleaning. Some Disinfectants even is the residual kill time of What require a “dwell time” to disinfectants? most reach the log reduction advertised.
  • 23. 4 Infection Prevention Layers 1. 2. 3. 4. Hand Sanitization / Continuous Protection Clothing Disinfection / Protection Surface Cleaning / Disinfection Surface Continuous Protection o Antifouling and anti-adhesive coatings o Zwitterionic polymer biomimetic surfaces o Antimicrobial coatings and surface technologies
  • 24. Surface Continuous Protection • Historical Evolution o Antifouling and anti-adhesive coatings o Zwitterionic polymer biomimetic surfaces (both positive & negative charged molecules) o Antimicrobial coatings and surface technologies
  • 25. DID YOU KNOW? Americans touch an average of 300 infected surfaces every 30 minutes. One cell of staph can multiply into 17 million in just 48 hours. A Study conducted at the University of Arizona found that the most germ-infected objects were: 1. Cell phones 2. Desktops 3. Water fountain handles 4. Computer keyboards 5. Computer mice
  • 26. Common practices for reducing the exposure to pathogens on surfaces? • “Perceived Cleanliness” • Spot Cleaning when visible fluid or dirt appears • Temporarily Disinfecting the surfaces based on protocol What is the residual kill time of most disinfectants? Toxic Shields – frequently reapplied •
  • 27. 4 Infection Prevention Layers 1. 2. 3. 4. Hand Sanitization / Continuous Protection Clothing Disinfection / Protection Surface Cleaning / Disinfection Surface Continuous Protection o Antifouling and anti-adhesive coatings o Zwitterionic polymer biomimetic surfaces o Antimicrobial coatings and surface technologies
  • 28. Antifouling and anti-adhesive surface coatings • • • • Poly(ethylene glycol) coatings (PEG) Self-Assembled Monolayer (SAM) Diamond-like carbon (DLC) films Easy clean surfaces • • Pilkington Active <10 degrees contact angle Pilkington Hydrotech >130 degrees contact angle • BUT: It merely moves them elsewhere, where they will have to be dealt with by other microbicidal techniques.
  • 29. Zwitterionic polymer biomimetic surfaces • Mimic properties found in the lipid bilayers of biological membranes • Zwitterionic surfaces are biocompatible and non-thrombogenic discouraging adhesion of cells, both mammalian and microbial • BUT: Still do not fully address the problem of microbial contamination as they have no antimicrobial functionality.
  • 30. Antimicrobial coatings and surface technologies The 6 core technologies are: 1. 2. 3. 4. 5. 6. Microbicide-releasing surfaces Silver and silver-containing surfaces Copper and copper alloy surfaces Bacteriophage-modified surfaces Polycationic antimicrobial surfaces Light Activated Antimicrobial Agents (LAAAs)
  • 31. 1. Microbicide-releasing surfaces • The most well known is Microban • Microban incorporates Triclosan (chlorodichlorophenoxy-phenol) a broad spectrum phenolic antimicrobial. • BUT: It is only active against Bacteria, not virus, spores, or Volitile Organic Compounds (VOCs). It is toxic in aquatic systems and is an endocrine disruptor. Most concerning is that it degrades to Dioxin which is extremely hazardous to man.
  • 32. 2. Silver and silver-containing surfaces • To date, few organisms have developed resistance towards the silver ion as an antimicrobial. • BUT besides ―expense‖ there are a couple of drawbacks: 1. They are non-permanent (leaching), relying on diffusible antimicrobials to which microbes can develop resistance. 2. Possible Ag ion cytotoxicity towards mammalian cells
  • 33. 3. Copper and copper alloy surfaces • Brass is less effective than pure copper but still exhibits antimicrobial activity • Alloys have improved aesthetic and mechanical properties and may be more suited to real world applications • Door plates, handles and other surfaces could employ copper alloys, but it’s a relatively expensive solution
  • 34. 4. Bacteriophage-modified surfaces • Bacteriophages are viruses that infect prokaryotic cells. • Phages usually target individual species of bacteria, bind to their surface, inject their genetic material and replicate within the bacterial host. • BUT they are not practical in general settings where specific targets may not be few enough and viruses, spores etc. are not addressed at all. Also of concern is Phage resistant strains.
  • 35. 5. Polyatomic Antimicrobial Surfaces • Polyethyleneimines (PEIs) • A positively charged moiety is required—this keeps the hydrophobic chains separated and erect from the surface, and also electrostatically attracts microbes, due to the net negative charge on their surface. • BUT, their mechanical stability and longevity have not been described and it is still yet to be seen how well they might respond to the rigors of use and indeed cleaning in a clinical setting.
  • 36. 6. Light Activated Antimicrobial Agents (LAAAs) • Photosensitiser (PDT Refinement) • PDT is a form of indirect phototherapy, in which light is used as a means of activating the curative agent. • Titanium Dioxide Photocatalysis • • • • (Effective with UV or visible spectrum though doping. eg. With Nitrogen or Tungsten oxide) Shown to be benign to the environment and humans, animals, birds, and aquatic systems. (No Toxicity) Highest binding, permanent, unless removed through abrasion Active against: Bacteria, Viruses, Spores (i.e. mold, mildew), VOCs and odors!
  • 37. WSE Available Alternatives Manufacturers Applicators • • • • Silver: Agion Triclosan : Microban Quanternary Ammonium: Aegis Photocatalyst: EcoActive What is the residual kill time of most disinfectants? • Bio Protect • Coating Specialist • SRS (OxiTitan)
  • 38. Antimicrobial Surface Coatings Comparison Coating Class Surface Photocatalyst Quaternary Ammonium Silver Triclosan Active Component(s) Mode of Action Effective Against: Bacteria Viruses Zinc, Titanium Dioxide Contact Photo-Oxidation Ammonium Chloride Silver Ions Phenoxy Phenols (PCPP) Contact Dilute Chloride Salts Leaching Heavy Metal in H2O Leaching Poison Active Bactericide Active Virucide Spores VOCs Odors Toxicity Risks To: Humans Animals & Birds Aquatic Systems Active Sporicide All All Bacteriostatic Ineffective Against Nonenveloped Viruses Fungistatic No Bacterial only No No No High Toxicity to Skin and Eyes High Toxicity to Skin and Eyes High Toxic, Zero Discharge Allowed Environmental Fate Risk None 5-Year Degradation Time Resistant Bacteria Promotion No No UV Damage Protection 95% No Metal Corrosion Protection Yes Corrosive Hydrophilic Self-Cleaning Yes No Application Method Water based spray Spray Treatable Surfaces All Substrates and Textiles Hard Surface or Textile New or Existing Durability Very High Binding Removed by Surfactants (Detergents or Soap) Service Interval 6 mo. - 3 Years 1-3 months unless cleaned Regulatory Guidance US EPA FIFRA 25B US EPA FIFRA Minimum Risk Pesticide Registered Exempt From Registration Bactericide Virucide Bactericide No Sporicide No Bacterial Only No No Bacterial Only Bio-Accumulative Bio-Accumulative Highly Toxic, Bio-Accumulative Very High Yes No No No Epoxy Paint Paintable Endocrine Disruptor Endocrine Disruptor Toxic Incorporated Incorporated at Manufacture Repaint US EPA Registered Currently Restricted for Review Item Replacement US EPA Registered Under Regulatory Review EU banned Degrades to Dioxin Yes No No No Incorporated at Manufacture Incorporated at Manufacture
  • 39. The best combinative surface solution available Surface Recontamination Shield (SRS) A Professionally applied antimicrobial smart coating for continuous protection against bacteria, viruses, mold and fungi for a cleaner, healthier environment. What is the residual kill time of most disinfectants? This coating is an energetic trap for microbes and Volatile Organic Compounds (VOCs) at a molecular level, completing their destruction through photocatalytic oxidation (PCO).
  • 40. US Independent Lab Testing The tests were designed to determine the efficacy of the antimicrobial coatings in the most adverse conditions by giving the bacteria the optimal growth environment. ALL LAB TESTS USED ONLY TYPICAL ARTIFICIAL ROOM LIGHTING. The presence of natural light or greater artificial lighting will increase the efficacy of the coating in bacterial, virus and VOC reduction. What is the residual kill time of Tests by leading US laboratories show strong, persistent and protective most disinfectants? cleaning power in real world conditions: 98% reduction of deadly VRE bacteria in 15 minutes; prolonged virus reduction of 89% over 24 hours and strong reductions of MRSA and Staph; 91% reduction of C. difficile spores over 24 hours and 99% reduction of hydrogen sulfide over 24 hours.
  • 41. SRS’s Multiple Attributes • Antimicrobial---Continuously kill all microbes contacting the surface • Superhydrophilic---Clean the surface continuously • 95% UV Protection---Protects any surface from sun damage What is the residual kill time of most disinfectants? • Anti-Corrosive---Protect metals against corrosion • VOC Elimination---Destroys Pollutants and Odors • Lowest Comprehensive Cost - Economically Effective
  • 42. Antimicrobial SRS deactivates ALL dangerous microbes and restrains proliferation by damaging their components through radical oxidation. This broad spectrum photo-mineralization of pathogens is continuous and permanent. Does not cause resistant strains of microbes becauseWhat is the residual kill time of its killing mechanism is strictly oxidative, not disinfectants? most enzymic or antibiotic. Antimicrobial coatings are protectants not disinfectants…they work in between cleanings.
  • 43. SRS is Superhydrophilic What is the residual kill time of most disinfectants?
  • 44. Self-Cleaning What is the residual kill time of most disinfectants?
  • 45. SRS’s UV Protection • The damaging rays of Ultraviolet (UV) light cause billions of dollars of damage to paints, plastics and textiles exposed What is the residual kill time of most disinfectants? to sunlight. • The SRS works as sunscreen on surfaces
  • 46. Oxy-Titan is Anti-Corrosive What is the residual kill time of most disinfectants?
  • 47. VOC & Odor Reduction  SRS removes odors and breaks down dangerous VOCs and pollutants in the air.  This safe, persistent cleansing of the air occurs using both natural sunlight and, most importantly, visible light indoors.?
  • 48. SRS….How long will it last?  The coating can only be removed by taking part of the substrate off through high friction polishing or abrasions.  One treatment will last up to 1 year. What is the residual kill time of most disinfectants? surface is dry the  Once the coating becomes one with the substrate and cannot be removed without removing the substrate
  • 49. SRS….How to prove the product is still working PCO™ Verification Ink • A quick and easy visible quality check! • Safe, water soluble, reaction dye • The ink will changeWhat is the minutes or less in a few residual kill time of from blue to pink most disinfectants? • Color change is proof that the SRS is protecting the surface, killing bacteria and viruses and breaking down VOCs (the odor reduction is self evident)
  • 50. Messaging for your facility… Display the SAFE STAMP in your facilities to instantly communicate that additional precautions have been taken to ensure a healthy environment. What is the residual kill time of most disinfectants?
  • 51. How the SRS is applied Original Sphere Electrostatics OFF Electrostatics ON  Professional Electrostatic Spray System  Ensures efficacy of coverage  70 Times more coverage than conventional What is the residual kill time of sprayers. most disinfectants?  Treated surface dries in less than 30 seconds  40 Times greater than the force of gravity
  • 52. Click pictures to view Videos Training and Assisted Living Facility Project Example Electrostatic Spraying Diamond Building Electrostatic Spraying What is Electrostatic Spraying?
  • 53. Application Methods Self Application: 800 sq/ft per gallon. HVLP Application: 1200-1500 sq/ft per gallon ESS Application: 3300-3600 sq/ft per gallon Due to the droplet size each application process administers, the amount of coverage has considerable cost variance and volume of product use.
  • 54. Comparative Cost for ESS Protection • Triclosan (MicroBan) – EU Banned and under Regulatory Review in the U.S. • Silver (Agion, HeiQ) > $1.50/sq. ft. (plus application fee) • Quaternary Ammonium (Aegis, and 45 other registrants) Highly Toxic to skin and eyes and all aquatic systems [zero discharge allowed] > 2 cents/sq. ft. (plus application fee) • Surface Photocatalyst (EcoActive and several private labels) < 5 cents/sq. ft. (plus application fee)
  • 55. How we do a Project • Determine the IC needs including persons surfaces and areas to be treated. • Assess hand, clothing and surface usage. What is the residual kill time of • Measure SQFT of most disinfectants? footprint, walls, equipment, counters, desks, and other surfaces.
  • 56. More Information on Selecting Antimicrobials: Household Cleaning - University of Nebraska- Lincoln Selecting an Appropriate Sanitizer or Disinfectant National Resource Center for Health and Safety in Child Care and Early Education Cleaning Up Antimicrobial Hand Soaps - Johns Hopkins School of Public Health Disinfection and Remediation Guidelines for Pools and Spas - Centers for Disease Control and Prevention Healthy Swimming - Centers for Disease Control and Prevention Cleaning, Sanitizing, and Disinfecting in Child Care Settings - National Resource Center for Health and Safety in Child Care and Early Education
  • 57. Surfaces and antimicrobial surface coatings in the epidemiology of HAIs *Hospital Acquired Infections - HAIs)
  • 58. 1. Hospital Grade Cleansing/Disinfectant 2. Non-Alcohol Based Hand Sanitizer/Protectant 3. Disinfection/Antimicrobial Clothing Protection 4. Continuous Antimicrobial Surface Protection Solution Analysis & Design Negotiation & Procurement Service Installation Accountability For More INFORMATION in how OXYTITAN can be of benefit to your Community Chris.Beckman@WilkinsSolutions.com / 888-460-4050 / www.wilkinssolutions.com

Editor's Notes

  1. Infection Control for your home or place of work from the spreading all forms of microbes, including disease causing germs! OxiArmor an oxidizing coating providing continuous protection against bacteria, viruses, mold and mildew, while also eliminating odors. One application by OxiArmor will fight germs for up to 2 years. The OxiArmor applied coating has been extensively lab and field tested to prove it non-toxic, non-leaching and completely safe for humans, pets and the environment. The solution consists of titanium dioxide and zinc Nano crystals in a water based solution. Unlike some other coatings, OxiArmor provides a “Green” Technology which contains no poisons or heavy metals.Our technicians will apply a safe, transparent, and odorless coating to surfaces in the home or place of business. The coating attracts, traps and kills bacteria and viruses (including infectious strains) using photo catalytic oxidation. OxiArmor’s applied coating provides ongoing germ protection for up to 2 years. Germ Prevention 24/7 through Surface Protection!
  2. Many Educational Systems and numerous Government agencies including the U.S. Navy banned all Alcohol Based hand sanitizers more than a year ago.
  3. Just last fall, the CDC recommendations were updated to promote the use of alcohol free hand sanitizers where the use of alcohol products may be dangerous. This change was triggered by the increased push back against the oldertechnology alcohol sanitizers and the dramatic increase in poison control events associated with their proliferation.
  4. Pure Shield - foaming hand sanitizer and 24 hour or 10 hand washings antimicrobial shield
  5. Not all Non-Alcohol based sanitizers are the same…Active Ingredient in many other Non-Alcohol based sanitizers is Triclosan which is rated as a level 7 high hazard in the Cosmetics Safety Database [3] Triclosan has been shown to accumulate biosolids the in environment, one of the top seven organic contaminants in waste water according to the National Toxicology Program[46] Triclosan leads to various problems with natural biological systems,[47] and triclosan, when combined withchlorine e.g. from tap water, produces dioxins, a probable carcinogen in humans.[48] However, 90-98% of triclosan in waste water biodegrades by both photolytic or natural biological processes or is removed due to sorption inwaste water treatment plants. Numerous studies show that only very small traces are detectable in the effluent water that reaches rivers. Triclosan is currently being reviewed by the FDA due to possible health hazards.
  6. From the uniforms you go to work in, to the soft, soothing blankets you lay your children down to sleep with, fabrics meet basic human needs and provide some of the most precious comforts of life. FabricAide® helps protect all the washable fabrics that touch your life. Harmful microbial contaminants like bacteria can survive for weeks on fabrics, allowing it to transfer to other objects or people. FabricAide® helps solve this problem by creating an environmentally friendly antimicrobial barrier on fabrics that works constantly to inhibit the growth of bacteria, mold and fungi for up to 90 days.
  7. Just last fall, the CDC recommendations were updated topromote the use of alcohol free hand sanitizers where the useof alcohol products may be dangerous. This change wastriggered by the increased push back against the oldertechnology alcohol sanitizers and the dramatic increase inpoison control events associated with their proliferation.
  8. WHAT SURFACECLEAN™ KILLSAntibiotic-Resistant Bactericidal Activity:Community Associated Methicillin Resistant Staphylococcus aureus (CA-MRSA) (NRS 123) Genotype USA 400 (NRS384) Genotype USA 300Methicillin resistant staphylococcus aureus (MRSA), (ATCC 33593)Vancomycin resistant Enterococcus faecalis (VRE), (ATCC 51575)Vancomycin intermediate resistant Staphylococcus aureus (VISA), (CDC Isolate 99287)Methicillin resistant Staphylococcus epidermidis (MRSE), (ATCC 51625)Bactericidal Activity:Staphylococcus aureus, (ATCC 6538)Pseudomonas aeruginosa, (ATCC 15442)Salmonella choleraesuis, (ATCC 10708)Escherichia coli, (ATCC 11229)Escherichia coli O157:H7, (ATCC 43895)Listeria monocytogenes, (ATCC 35152)Salmonella typhi, (ATCC 6539)Streptococcus pyogenes (Necrotizing Fasciitis-Group A) (V.A. Medical Center Isolate 04001)Yersinia enterocolitica, (ATCC 23715)Enterococcus faecium, (ATCC 6569)Corynebacterium ammoniagenes, (ATCC 6871)Virucidal Activity:Avian Influenza A Virus (H3N2), (Avian Reassortant) (ATCC VR-2072)Avian Influenza Virus Type A (Turkey/WIS/66), (H9N2)SARS Associated Coronavirus (ZeptoMetrix)Paramyxovirus (Mumps) (ATCC VR-1438)Hepatitis A Virus (HAV)Rhinovirus Type 39 (ATCC VR-340)Rotovirus
  9. -DCL’s like amorphous hydrogenated carbon have possible applications for stents or replacement joints, venous and renal catheters-Hydrophobic commercial coatings such as Pilkington’s show marked bacterial shedding properties when below 10 degrees and above 130 degrees compared to glass controls and other commercial coated glass products. BUT, the principle drawback of all hydrophobic easy clean materials is that whilst preventing microbial contamination in the area treated, it does not address the problem of pathogenic microbes which are incident upon the surface—it merely moves them elsewhere, where they will have to be dealt with by other microbicidal techniques.
  10. The Z head can associate a large amount of water - making the material essentiallyhydrophilic. This leads to reversible interactions between incident microbes and the surface—discouraging adhesion of cells, both mammalian and microbial. It may be good for indwelling biomedical devices. because their biomimetic nature firstly affords biocompatibility by reducing attachment of human cells to the device (which can cause encrustation) and secondly afford protection against bacterial biofilm formation which can leadto device-related infections. BUT, They still do not fully address the problem of microbial contamination as they have no antimicrobial functionality.
  11. It acts like a disinfectant i.e. killing outside in, rather than an antibiotic, i.e. inside out.With a Microban product, the antimicrobial leaches from the surface of the product to perform the antimicrobial function. This means that effectively they are non-permanent. There has also been significantconcern about possible development of Triclosan resistance;furthermore some studies suggest that Triclosan can, under the action of UV light, produce dioxins, which areextremely hazardous to man.
  12. Phages usually target individual species of bacteria, bind to their surface, inject their genetic material and replicate within the bacterial host. If the replication of the phage is by what is known as a ‘‘lytic’’ process the eventual result is the lysis of the host cell, and the release of more phages.The replication process is self propagating until there is no more host organism available. As a result of this, lytic bacteriophages make interesting candidates for antimicrobial is specific settings.There are a number of potential problems with Phages. The first is the inherent specificity of the phage for individual bacterial species. Whilst this is excellent for a targeted in vivo therapy, it is less useful for a surface, where a number of different organisms, not may be present. A combination of phages would have to be used to increase the spectrum of activity, but this may leave out potentially harmful organisms. One other area of concern is that of phage resistance—bacteria can become resistant to a phage through mutations which change the susceptibility of the cell wall to the phage enzymes used to enable injection of genetic material.
  13. The Doping creates:1. More efficient harvesting of energy from absorbed photons, in effect enabling more energy to be absorbed. 2. Expansion of the wavelength range over which photons can be harvested, so that visible light energy can be used. 3. Maintain separation of charges in the semiconductor, thereby preventing electron-hole recombination and amplifying the photo-redox processes at the catalyst surface
  14. Hospital acquired infections are a significant health concern in developed countries. Microbes such as MRSA and C. difficile have been implicated with a large number of deaths as well as enormous additional healthcare costs. The growing resistance of microbes to antibiotics is a significant cause for concern. This has prompted improved cleaning protocols within hospitals. Despite this, HAIs have not been, and probably never will be, completely eradicated. The development of surfaces and coatings that can actively kill microbes is an important component of maintaining a microbially-clean environment and a wide number of methods have been developed. Ideally these antimicrobial surfaces shouldbe permanent, hard-wearing and work under hospital conditions.The mode of action in killing microbes needs to function simultaneously through multiple pathways, so that the development of resistance, as seen for antibiotics and diffusible antimicrobials, is avoided. In that context, the light-activated antimicrobials offer particular promise as they function bygenerating reactive oxygen species that act on multiple targets within microbes. Furthermore, titanium dioxide coatings offer both reactive oxygen species and a super hydrophilic surface that is both easy to clean and hard for a microbe to adhere to.
  15. How does OxiArmor apply the antimicrobial coating?OxiArmor utilizes the technology of Electrostatic Spraying to bond the antimicrobial coating to any surface. Electrostatic Spraying uses compressed air and a state of the art spay nozzle to atomize the spray and carry droplets onto the surfaces in a turbulent cloud. The droplets are electrically charged and attract to the surfaces for optimal and even coverage allowing 75% more coverage than conventional sprayers.The service technicians from OxiArmor use an electrostatic spray treatment to ensure your surfaces are fully coated. Our state of the art electrostatic sprayers provide a negative charge to the dispensed droplets, giving them a force of attraction 40 times stronger than gravity. This allows droplets to move upwards or in reverse to coat hidden surfaces which carry a positive charge. All nooks and crannies, where germs can lurk, will be treated with this progressive spraying system. See the sample videos below on the effectiveness of electrostatic spraying.View the Frequently Asked Questions page to learn more about OxiArmor.
  16. Remember, while a critical path to be controlled Surfaces are only one of the 4 layers needing to be addressed. Without a strict hygiene regime, and the continuous protection of hands and clothing as transport mechanisms, these measures will have limited benefit.