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Affairs of the Heart

    Veronica Bonales, M.D.
   CEP Emergency Physician
  Redwood Memorial Hospital
Affairs of the Heart
Affairs of the Heart

Anatomy of heart and electrical system

Heart problems - Arrythmias

Heart problems - Ischemia

Mega Code with new AHA Guidelines
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Tissues


        Cardiac Myocytes
         Specialized
         Intrinsic Rhythm
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Heart Anatomy
Intrinsic Rhythm


SA Node - 100 beats per minute (70 normal)

AV Node - 40 - 60 beats per minute

Purkinje Fibers - 30 - 40 beats per minute
Fight or Flight / Rest
         and Digest
Sympathetic and Parasympathetic Nervous
System - on SA Node

  Sympathetic

    Norepinephrine (beta-1 receptors)

  Parasympathetic

    Vagus Nerve (ACh)
Balance
Cardiac Filling
Cardiac Filling
When Good Hearts Go
       Bad
Heart Problems -
   Arrhythmias


Rate
Rhythm
Normal Sinus
Heart Problems - Rate
Heart Problems - Rate


Too fast
Too slow
Not beating at all
Heart Problems -
        Rhythm

Regular
Irregular
Heart Problems -
        Rhythm

Regular
Irregular
Atrial Fibrillation
3rd Degree Heart Block
3rd Degree Heart Block
Atrial Flutter
Ventricular Tachycardia
Torsades de Pointes
Ventricular Fibrillation
Cardiac Drugs
Drugs

Aspirin           Furosemide

Atropine          Lidocaine

Adenosine         Morphine

Amiodarone        Nitroglycerin

Epinephrine       Oxygen
Drugs

Aspirin           Furosemide

Atropine          Lidocaine

Adenosine         Morphine

Amiodarone        Nitroglycerin

Epinephrine       Oxygen
Sympathetic and Parasympathetic Nervous
System - on SA Node

  Sympathetic

    Norepinephrine (beta-1 receptors)

  Parasympathetic

    Vagus Nerve (ACh)
Atropine
increases ļ¬ring of the sinoatrial node (SA) and
conduction through the atrioventricular node (AV) of
the heart, opposes the actions of the vagus nerve,
blocks acetylcholine receptor sites
Atropine
increases ļ¬ring of the sinoatrial node (SA) and
conduction through the atrioventricular node (AV) of
the heart, opposes the actions of the vagus nerve,
blocks acetylcholine receptor sites




                       x
Adenosine
Blocks the AV node
Adenosine
Blocks the AV node




                     x
Amiodarone

Beta blocker, prolongs action potential via
sodium channels and potassium channels
Amiodarone

Beta blocker, prolongs action potential via
sodium channels and potassium channels




                    x
Epinephrine

Works at ACh junctions
Epinephrine

Works at ACh junctions
Lidocaine
Blocks sodium channels
Lidocaine
Blocks sodium channels




            x
Lidocaine
Blocks sodium channels




            x
            x
Heart Problems -
    Ischemia
Coronary Anatomy
Coronary Anatomy
The Heart Electric
EKG Regions
STEMI
STEMI
LM
LM
     LCx
LAD
LM
     LCx
LAD
LM
     LCx
Angiography
 Opening the lesion
EMS called to ofļ¬ce building with report
of ā€œman down.ā€ Found 54 y.o. male patient
in PEA arrest. CPR & ACLS for 35
minutes & pronounced at scene.
MEGA Code
54 yo with hx of multiple medical problems riding in car
with family on Sunday afternoon, going home after lunch.
54 yo with hx of multiple medical problems riding in car
with family on Sunday afternoon, going home after lunch.

911 call - Family reports patient ā€œpassed outā€ in car.
Pulled over to side of the road and family performing
CPR.
54 yo with hx of multiple medical problems riding in car
with family on Sunday afternoon, going home after lunch.

911 call - Family reports patient ā€œpassed outā€ in car.
Pulled over to side of the road and family performing
CPR.

FD is ļ¬rst on scene.... What do you do?
54 yo with hx of multiple medical problems riding in car
with family on Sunday afternoon, going home after lunch.

911 call - Family reports patient ā€œpassed outā€ in car.
Pulled over to side of the road and family performing
CPR.

FD is ļ¬rst on scene.... What do you do?

  *AHA - change from ABC to CAB
54 yo with hx of multiple medical problems riding in car
with family on Sunday afternoon, going home after lunch.

911 call - Family reports patient ā€œpassed outā€ in car.
Pulled over to side of the road and family performing
CPR.

FD is ļ¬rst on scene.... What do you do?

  *AHA - change from ABC to CAB

  *Patients should receive CPR until an AED is available
AHA:
  CPR should be fast (>100) and deep (>2
  inches)
  Rotate compressor every 2 minutes
  No ventilation for ļ¬rst 18 sec (30
  compressions)
  If no advanced airway 30:2 ratio
FD applies AED; shock advised. One shock given with
ROSC. EMS arrives at this point. What do you do?
FD applies AED; shock advised. One shock given with
ROSC. EMS arrives at this point. What do you do?
EMTā€™s place patient in back of ambulance and see this on
monitor....
EMTā€™s place patient in back of ambulance and see this on
monitor....
EMTā€™s place patient in back of ambulance and see this on
monitor....




ā€œAndy, Andy, are you ok? Patient is unresponsive. No
pulse. What do you do?
PEA Arrest
PEA Arrest

    CPR for 2 minutes
PEA Arrest

    CPR for 2 minutes

    Epinephrine every 3 minutes
PEA Arrest

    CPR for 2 minutes

    Epinephrine every 3 minutes

    Consider advanced airway (passive O2 via mask with
    an open airway showed improved survival)
PEA Arrest

    CPR for 2 minutes

    Epinephrine every 3 minutes

    Consider advanced airway (passive O2 via mask with
    an open airway showed improved survival)

    8 - 10 breaths per minute, continuous CPR
Coronary Artery
   Perfusion Pressure




9 strokes
Epinephrine x 2 (*no atropine), intubated with minimal
interruption of chest compressions (*<10 sec), wave-form
capnography in place...
Epinephrine x 2 (*no atropine), intubated with minimal
interruption of chest compressions (*<10 sec), wave-form
capnography in place...
Epinephrine x 2 (*no atropine), intubated with minimal
interruption of chest compressions (*<10 sec), wave-form
capnography in place...
Then on the monitor you see this....
Then on the monitor you see this....
Then on the monitor you see this....




Now what?
Ventricular tachycardia
   Shock
   CPR for 2 minutes
Then on the monitor you see this....
Then on the monitor you see this....
Then on the monitor you see this....




Now what?
Ventricular ļ¬brillation
Ventricular ļ¬brillation
   Shock
Ventricular ļ¬brillation
   Shock
   CPR for 2 minutes
Ventricular ļ¬brillation
   Shock
   CPR for 2 minutes
   Another drug....?
Ventricular ļ¬brillation
   Shock
   CPR for 2 minutes
   Another drug....?
   Amiodarone & treat reversible causes
Ventricular ļ¬brillation
   Shock
   CPR for 2 minutes
   Another drug....?
   Amiodarone & treat reversible causes
Ventricular ļ¬brillation
   Shock
   CPR for 2 minutes
   Another drug....?
   Amiodarone & treat reversible causes
Reversible Causes:
Reversible Causes:

    Hypovolemia
Reversible Causes:

    Hypovolemia
      Hypoxia
Reversible Causes:

    Hypovolemia
      Hypoxia
    H+ (Acidosis)
Reversible Causes:

    Hypovolemia
      Hypoxia
    H+ (Acidosis)
   Hypo/Hyper K+
Reversible Causes:

    Hypovolemia
      Hypoxia
    H+ (Acidosis)
   Hypo/Hyper K+
    Hypothermia
Reversible Causes:

    Hypovolemia      Tension PTx
      Hypoxia
    H+ (Acidosis)
   Hypo/Hyper K+
    Hypothermia
Reversible Causes:

    Hypovolemia      Tension PTx
      Hypoxia        Tamponade
    H+ (Acidosis)
   Hypo/Hyper K+
    Hypothermia
Reversible Causes:

    Hypovolemia      Tension PTx
      Hypoxia        Tamponade
    H+ (Acidosis)       Toxins
   Hypo/Hyper K+
    Hypothermia
Reversible Causes:

    Hypovolemia       Tension PTx
      Hypoxia          Tamponade
    H+ (Acidosis)        Toxins
   Hypo/Hyper K+     Thrombosis, PE
    Hypothermia
Reversible Causes:

    Hypovolemia          Tension PTx
      Hypoxia             Tamponade
    H+ (Acidosis)           Toxins
   Hypo/Hyper K+        Thrombosis, PE
    Hypothermia      Thrombosis, Coronary
Amiodarone 300mg loading dose given with
ROSC.
Now what?
Amiodarone 300mg loading dose given with
ROSC.
Now what?
Amiodarone 300mg loading dose given with
ROSC.
Now what?
AHA Post Cardiac Arrest Goals
    - control body temperature to
   optimize survival & neurological
   recovery
    - Tx of ACS (Cath Lab Activation)
Patient arrives in hospital E.D. Therapeutic hypothermia
started with cold saline in the ļ¬eld. Patient placed on
cooler. EKG showed STEMI. Cath Lab activated and
patient underwent angiography which showed LAD lesion.
Stented in the Cath Lab and went to CCU where
rewarmed about 24 hours later. Extubated and
eventually went to cardiac rehab.
Questions...??

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