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HEMATOPOIETIC STEM
CELL TRANSPLANTATION
- THE BASICS
Dr. Vijay Reddy
Introduction
 An accomplished hematologist/oncologist, Dr.
Vijay Reddy has focused much of his work on
hematopoietic stem cell transplants and other
elements of hematologic oncology. Dr. Vijay
Reddy has published on this topic in such journals
as Biology of Blood and Bone Marrow
Transplantation and Experimental Hematology.
Hematopoietic stem cells are incompletely
developed cells that can differentiate into any type
of blood cell, including platelets and white blood
cells. Found in marrow as well as in the blood
itself, they serve to renew the blood on a daily
basis.
Hematopoietic Stem Cell
Transplantation
 Over the past half-century, scientists have used this natural
function of the hematopoietic stem cell to increase blood cell
production and strengthen immune functions in patients with
certain cancers.
Medical professionals source hematopoietic stem cells from
the patient's own body or that of a donor. Physicians typically
search for a donor that is a complete human leukocyte
antigen (HLA) match, whether that individual be related or
unrelated to the patient. Partial matches may be appropriate
in some cases, and there has been much interest in the use
of half matches for haploidentical transplantation of T-cell-
depleted cells. Patients may also elect to receive cord blood
transplantation from a cord blood bank or an autologous
transplant from the patient's own body.

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Hematopoietic Stem Cell Transplantation - The Basics

  • 1. HEMATOPOIETIC STEM CELL TRANSPLANTATION - THE BASICS Dr. Vijay Reddy
  • 2. Introduction  An accomplished hematologist/oncologist, Dr. Vijay Reddy has focused much of his work on hematopoietic stem cell transplants and other elements of hematologic oncology. Dr. Vijay Reddy has published on this topic in such journals as Biology of Blood and Bone Marrow Transplantation and Experimental Hematology. Hematopoietic stem cells are incompletely developed cells that can differentiate into any type of blood cell, including platelets and white blood cells. Found in marrow as well as in the blood itself, they serve to renew the blood on a daily basis.
  • 3. Hematopoietic Stem Cell Transplantation  Over the past half-century, scientists have used this natural function of the hematopoietic stem cell to increase blood cell production and strengthen immune functions in patients with certain cancers. Medical professionals source hematopoietic stem cells from the patient's own body or that of a donor. Physicians typically search for a donor that is a complete human leukocyte antigen (HLA) match, whether that individual be related or unrelated to the patient. Partial matches may be appropriate in some cases, and there has been much interest in the use of half matches for haploidentical transplantation of T-cell- depleted cells. Patients may also elect to receive cord blood transplantation from a cord blood bank or an autologous transplant from the patient's own body.