Brief powerpoint presentation about pain and plantar fascitis

1. Pain and Plantar Fascitis

3. Microtrauma
Activation of
Nociceptive
receptors
Tissue damage

4. Pain Mediators
Damaged tissue
Proteases
ATP
K+

5. Pain Mediators
Damaged tissue
Proteases
ATP
K+
Causes production of
bradykinin which can
directly depolarize the
nociceptors

6. Pain Mediators
Damaged tissue
Proteases
ATP
K+
Causes production of
bradykinin which binds
to a nociceptor
Nociceptor
depolarization

7. Pain Mediators
Damaged tissue
Proteases
ATP
K+
Causes production of
bradykinin which binds
to a nociceptor
Nociceptor
depolarization
Nociceptor
depolarization

8. Pain Mediators
Damaged tissue
Proteases
ATP
K+
Activation of
Nociceptive receptors

9. Transduction