In the banking business, there are many combinatorial design options, e.g. in the areas of portfolio or risk management. Main Incubator, the R & D unit of Commerzbank, is interested in the use of modern quantum technologies in order to digitally transform and optimize business processes. The presentation introduces the securitization business and shows the combinatorial aspects of the calculations and its implementation in quantum algorithms. The methodology to find the right subject, the know-how transfer and the cooperation of specialists at Main Incubator and Fujitsu will be presented. Special challenges, their solution and the finally achieved results complete the picture along with an outlook into the future.