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National Institute of Mental Health

For More Information on Depression

Citations

Reprints

visit the national library of medicine’s
medlineplus http://medlineplus.gov
en español http://medlineplus.gov/spanish

1. Kessler rc, chiu Wt, Demler o, merikangas Kr,
Walters ee. prevalence, severity, and comorbidity of
12-month Dsm-iv disorders in the national
comorbidity survey replication. Arch Gen Psychiatry.
2005 Jun; 62(6):617–27.

this publication is in the public domain and may be reproduced
or copied without permission from nimH. We encourage you to
reproduce it and use it in your efforts to improve public health.
citation of the national institute of mental Health as a source
is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use
these guidelines:

for information on clinical trials
http://www.nimh.nih.gov/health/trials/index.shtml
national library of medicine clinical trials database
http://www.clinicaltrials.gov
information from nimH is available in multiple formats. You
can browse online, download documents in pDf, and order
materials through the mail. check the nimH website at
http://www.nimh.nih.gov for the latest information on
this topic and to order publications. if you do not have
internet access please contact the nimH information
resource center at the numbers listed below.
National Institute of Mental Health
science Writing, press & Dissemination Branch
6001 executive Boulevard
room 8184, msc 9663
Bethesda, mD 20892-9663
phone: 301-443-4513 or
1-866-615-nimH (6464) toll-free
ttY: 301-443-8431 or
1-866-415-8051 toll-free
faX: 301-443-4279
e-mail: nimhinfo@nih.gov
Website: http://www.nimh.nih.gov

2. Williams s, Dale J. the effectiveness of treatment for
depression/depressive symptoms in adults with cancer:
a systematic review. British Journal of Cancer. 2006
feb 13; 94(3):372–90.
3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer
incidence and survival? Nature Clinical Practice:
Oncology. 2008 aug; 5(8):466–75.
4. Jacobsen pB, Jim Hs. psychosocial interventions for
anxiety and depression in adult cancer patients:
achievements and challenges. CA: A Cancer Journal for
Clinicians. 2008 Jul–aug; 58(4):214–30.

	 nimH does not endorse or recommend any commercial prod-

n

ucts, processes, or services, and our publications may not be
used for advertising or endorsement purposes.

	 nimH does not provide specific medical advice or treatment

n

recommendations or referrals; our materials may not be used
in a manner that has the appearance of such information.

	 nimH requests that non-federal organizations not alter our

n

publications in ways that will jeopardize the integrity and
“brand” when using the publication.

	 addition of non-federal Government logos and website links

n

may not have the appearance of nimH endorsement of any
specific commercial products or services or medical treatments or services.
if you have questions regarding these guidelines and use of nimH
publications, please contact the nimH information resource
center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov.

For More Information on Cancer
National Cancer Institute
office of communications and education/
public inquiries office
6116 executive Boulevard, suite 300
Bethesda, mD 20892-8322
phone: 1-800-4-cancer (1-800-422-6237)
e-mail: http://www.cancer.gov/contact
Website: http://www.cancer.gov

u.s. Department of HealtH anD Human services
national institutes of Health
national institute of mental Health
niH publication no. 11–5002
revised 2011

Depression and
Cancer
D

epression not only affects
your brain and behavior—

it affects your entire body.
Depression has been linked with
other health problems, including
cancer. Dealing with more than
one health problem at a time can
be difficult, so proper treatment is
important.

What is depression?
major depressive disorder, or depression, is a serious mental
illness. Depression interferes with your daily life and routine and
reduces your quality of life. about 6.7 percent of u.s. adults ages
18 and older have depression.1

Signs and Symptoms of Depression
n	

ongoing sad, anxious, or empty feelings

n	

feeling hopeless

n	

feeling guilty, worthless, or helpless

n	

feeling irritable or restless

n

loss of interest in activities or hobbies once enjoyable,
including sex

n	

feeling tired all the time

n

Difficulty concentrating, remembering details, or making
decisions

n	

Difficulty falling asleep or staying asleep, a condition
called insomnia, or sleeping all the time

n	

overeating or loss of appetite

n	

thoughts of death and suicide or suicide attempts

n

ongoing aches and pains, headaches, cramps, or digestive
problems that do not ease with treatment.

for more information, see the nimH booklet on Depression at
http://www.nimh.nih.gov/health/publications/depression/
index.shtml.

What is cancer?
cancer is a disease that develops when abnormal cells in your
body divide and multiply without control. normally, cells grow
and divide to produce more cells only when your body needs
them. But sometimes, cells keep dividing when new cells are
not needed. these extra cells may form a mass called a tumor.
tumors can be either benign, which means not cancerous, or
malignant, which is cancerous.
cancer cells can develop anywhere in the body and can spread to
other body parts through your blood and lymph systems. lymph

is a clear fluid that carries blood cells that fight infection and
disease throughout the body. lymph travels through a system
of vessels, much like blood vessels.
cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer
and symptoms can vary greatly depending on the location, or
the organs and tissue that are affected.

How are depression and cancer linked?
Depression is not regularly linked with cancer, and there is no
proof that one disease causes the other.2,3 However, when
faced with a diagnosis of cancer, you may feel extreme stress,
anger, sadness, or a number of other strong emotions. While
these feelings usually lessen over time, they can develop into
depression.
if you develop depression after learning you have cancer—or
were depressed before your diagnosis—your depression may
affect the course of your cancer2,3 as well as your ability to take
part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment.

How is depression treated in people who
have cancer?
Depression is diagnosed and treated by a health care provider.
treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective.
at present, the most common treatments for depression
include:
n

cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative
thinking styles and behaviors that may contribute to their
depression

n

selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa),
sertraline (Zoloft), and fluoxetine (prozac)

n

serotonin and norepinephrine reuptake inhibitor (snri),
a type of antidepressant medication similar to ssri that
includes venlafaxine (effexor) and duloxetine (cymbalta).

While currently available depression treatments are generally well tolerated and safe even if you’re being treated
for cancer, possible drug interactions and side effects
require careful monitoring. talk with your health care
provider about the medications you’re taking as well as
other treatment options. for the latest information on
medications, visit the u.s. food and Drug administration
website at http://www.fda.gov. not everyone responds
to treatment the same way. medications can take several
weeks to work, may need to be combined with ongoing
talk therapy, or may need to be changed or adjusted to
minimize side effects and achieve the best results.
along with cBt, additional forms of talk therapy have
been shown to help people with cancer manage their
depression, including4:
n

psychoeducation, which teaches you about your illness
and its treatment

n

stress management training, which teaches you different ways to cope with anxiety

n

problem-solving therapy, which can help you identify
problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve
those problems.

You can also join a support group, which provides an
important outlet for sharing the difficult emotions you’re
feeling. You can learn how to cope with your depression and your cancer from others who are going through
similar experiences.
more information about depression treatments can be
found on the nimH website at http://www.nimh.nih.
gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed
or know someone who is, don’t lose hope. seek help for
depression.
D

epression not only affects
your brain and behavior—

it affects your entire body.
Depression has been linked with
other health problems, including
cancer. Dealing with more than
one health problem at a time can
be difficult, so proper treatment is
important.

What is depression?
major depressive disorder, or depression, is a serious mental
illness. Depression interferes with your daily life and routine and
reduces your quality of life. about 6.7 percent of u.s. adults ages
18 and older have depression.1

Signs and Symptoms of Depression
n	

ongoing sad, anxious, or empty feelings

n	

feeling hopeless

n	

feeling guilty, worthless, or helpless

n	

feeling irritable or restless

n

loss of interest in activities or hobbies once enjoyable,
including sex

n	

feeling tired all the time

n

Difficulty concentrating, remembering details, or making
decisions

n	

Difficulty falling asleep or staying asleep, a condition
called insomnia, or sleeping all the time

n	

overeating or loss of appetite

n	

thoughts of death and suicide or suicide attempts

n

ongoing aches and pains, headaches, cramps, or digestive
problems that do not ease with treatment.

for more information, see the nimH booklet on Depression at
http://www.nimh.nih.gov/health/publications/depression/
index.shtml.

What is cancer?
cancer is a disease that develops when abnormal cells in your
body divide and multiply without control. normally, cells grow
and divide to produce more cells only when your body needs
them. But sometimes, cells keep dividing when new cells are
not needed. these extra cells may form a mass called a tumor.
tumors can be either benign, which means not cancerous, or
malignant, which is cancerous.
cancer cells can develop anywhere in the body and can spread to
other body parts through your blood and lymph systems. lymph

is a clear fluid that carries blood cells that fight infection and
disease throughout the body. lymph travels through a system
of vessels, much like blood vessels.
cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer
and symptoms can vary greatly depending on the location, or
the organs and tissue that are affected.

How are depression and cancer linked?
Depression is not regularly linked with cancer, and there is no
proof that one disease causes the other.2,3 However, when
faced with a diagnosis of cancer, you may feel extreme stress,
anger, sadness, or a number of other strong emotions. While
these feelings usually lessen over time, they can develop into
depression.
if you develop depression after learning you have cancer—or
were depressed before your diagnosis—your depression may
affect the course of your cancer2,3 as well as your ability to take
part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment.

How is depression treated in people who
have cancer?
Depression is diagnosed and treated by a health care provider.
treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective.
at present, the most common treatments for depression
include:
n

cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative
thinking styles and behaviors that may contribute to their
depression

n

selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa),
sertraline (Zoloft), and fluoxetine (prozac)

n

serotonin and norepinephrine reuptake inhibitor (snri),
a type of antidepressant medication similar to ssri that
includes venlafaxine (effexor) and duloxetine (cymbalta).

While currently available depression treatments are generally well tolerated and safe even if you’re being treated
for cancer, possible drug interactions and side effects
require careful monitoring. talk with your health care
provider about the medications you’re taking as well as
other treatment options. for the latest information on
medications, visit the u.s. food and Drug administration
website at http://www.fda.gov. not everyone responds
to treatment the same way. medications can take several
weeks to work, may need to be combined with ongoing
talk therapy, or may need to be changed or adjusted to
minimize side effects and achieve the best results.
along with cBt, additional forms of talk therapy have
been shown to help people with cancer manage their
depression, including4:
n

psychoeducation, which teaches you about your illness
and its treatment

n

stress management training, which teaches you different ways to cope with anxiety

n

problem-solving therapy, which can help you identify
problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve
those problems.

You can also join a support group, which provides an
important outlet for sharing the difficult emotions you’re
feeling. You can learn how to cope with your depression and your cancer from others who are going through
similar experiences.
more information about depression treatments can be
found on the nimH website at http://www.nimh.nih.
gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed
or know someone who is, don’t lose hope. seek help for
depression.
D

epression not only affects
your brain and behavior—

it affects your entire body.
Depression has been linked with
other health problems, including
cancer. Dealing with more than
one health problem at a time can
be difficult, so proper treatment is
important.

What is depression?
major depressive disorder, or depression, is a serious mental
illness. Depression interferes with your daily life and routine and
reduces your quality of life. about 6.7 percent of u.s. adults ages
18 and older have depression.1

Signs and Symptoms of Depression
n	

ongoing sad, anxious, or empty feelings

n	

feeling hopeless

n	

feeling guilty, worthless, or helpless

n	

feeling irritable or restless

n

loss of interest in activities or hobbies once enjoyable,
including sex

n	

feeling tired all the time

n

Difficulty concentrating, remembering details, or making
decisions

n	

Difficulty falling asleep or staying asleep, a condition
called insomnia, or sleeping all the time

n	

overeating or loss of appetite

n	

thoughts of death and suicide or suicide attempts

n

ongoing aches and pains, headaches, cramps, or digestive
problems that do not ease with treatment.

for more information, see the nimH booklet on Depression at
http://www.nimh.nih.gov/health/publications/depression/
index.shtml.

What is cancer?
cancer is a disease that develops when abnormal cells in your
body divide and multiply without control. normally, cells grow
and divide to produce more cells only when your body needs
them. But sometimes, cells keep dividing when new cells are
not needed. these extra cells may form a mass called a tumor.
tumors can be either benign, which means not cancerous, or
malignant, which is cancerous.
cancer cells can develop anywhere in the body and can spread to
other body parts through your blood and lymph systems. lymph

is a clear fluid that carries blood cells that fight infection and
disease throughout the body. lymph travels through a system
of vessels, much like blood vessels.
cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer
and symptoms can vary greatly depending on the location, or
the organs and tissue that are affected.

How are depression and cancer linked?
Depression is not regularly linked with cancer, and there is no
proof that one disease causes the other.2,3 However, when
faced with a diagnosis of cancer, you may feel extreme stress,
anger, sadness, or a number of other strong emotions. While
these feelings usually lessen over time, they can develop into
depression.
if you develop depression after learning you have cancer—or
were depressed before your diagnosis—your depression may
affect the course of your cancer2,3 as well as your ability to take
part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment.

How is depression treated in people who
have cancer?
Depression is diagnosed and treated by a health care provider.
treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective.
at present, the most common treatments for depression
include:
n

cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative
thinking styles and behaviors that may contribute to their
depression

n

selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa),
sertraline (Zoloft), and fluoxetine (prozac)

n

serotonin and norepinephrine reuptake inhibitor (snri),
a type of antidepressant medication similar to ssri that
includes venlafaxine (effexor) and duloxetine (cymbalta).

While currently available depression treatments are generally well tolerated and safe even if you’re being treated
for cancer, possible drug interactions and side effects
require careful monitoring. talk with your health care
provider about the medications you’re taking as well as
other treatment options. for the latest information on
medications, visit the u.s. food and Drug administration
website at http://www.fda.gov. not everyone responds
to treatment the same way. medications can take several
weeks to work, may need to be combined with ongoing
talk therapy, or may need to be changed or adjusted to
minimize side effects and achieve the best results.
along with cBt, additional forms of talk therapy have
been shown to help people with cancer manage their
depression, including4:
n

psychoeducation, which teaches you about your illness
and its treatment

n

stress management training, which teaches you different ways to cope with anxiety

n

problem-solving therapy, which can help you identify
problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve
those problems.

You can also join a support group, which provides an
important outlet for sharing the difficult emotions you’re
feeling. You can learn how to cope with your depression and your cancer from others who are going through
similar experiences.
more information about depression treatments can be
found on the nimH website at http://www.nimh.nih.
gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed
or know someone who is, don’t lose hope. seek help for
depression.
D

epression not only affects
your brain and behavior—

it affects your entire body.
Depression has been linked with
other health problems, including
cancer. Dealing with more than
one health problem at a time can
be difficult, so proper treatment is
important.

What is depression?
major depressive disorder, or depression, is a serious mental
illness. Depression interferes with your daily life and routine and
reduces your quality of life. about 6.7 percent of u.s. adults ages
18 and older have depression.1

Signs and Symptoms of Depression
n	

ongoing sad, anxious, or empty feelings

n	

feeling hopeless

n	

feeling guilty, worthless, or helpless

n	

feeling irritable or restless

n

loss of interest in activities or hobbies once enjoyable,
including sex

n	

feeling tired all the time

n

Difficulty concentrating, remembering details, or making
decisions

n	

Difficulty falling asleep or staying asleep, a condition
called insomnia, or sleeping all the time

n	

overeating or loss of appetite

n	

thoughts of death and suicide or suicide attempts

n

ongoing aches and pains, headaches, cramps, or digestive
problems that do not ease with treatment.

for more information, see the nimH booklet on Depression at
http://www.nimh.nih.gov/health/publications/depression/
index.shtml.

What is cancer?
cancer is a disease that develops when abnormal cells in your
body divide and multiply without control. normally, cells grow
and divide to produce more cells only when your body needs
them. But sometimes, cells keep dividing when new cells are
not needed. these extra cells may form a mass called a tumor.
tumors can be either benign, which means not cancerous, or
malignant, which is cancerous.
cancer cells can develop anywhere in the body and can spread to
other body parts through your blood and lymph systems. lymph

is a clear fluid that carries blood cells that fight infection and
disease throughout the body. lymph travels through a system
of vessels, much like blood vessels.
cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer
and symptoms can vary greatly depending on the location, or
the organs and tissue that are affected.

How are depression and cancer linked?
Depression is not regularly linked with cancer, and there is no
proof that one disease causes the other.2,3 However, when
faced with a diagnosis of cancer, you may feel extreme stress,
anger, sadness, or a number of other strong emotions. While
these feelings usually lessen over time, they can develop into
depression.
if you develop depression after learning you have cancer—or
were depressed before your diagnosis—your depression may
affect the course of your cancer2,3 as well as your ability to take
part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment.

How is depression treated in people who
have cancer?
Depression is diagnosed and treated by a health care provider.
treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective.
at present, the most common treatments for depression
include:
n

cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative
thinking styles and behaviors that may contribute to their
depression

n

selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa),
sertraline (Zoloft), and fluoxetine (prozac)

n

serotonin and norepinephrine reuptake inhibitor (snri),
a type of antidepressant medication similar to ssri that
includes venlafaxine (effexor) and duloxetine (cymbalta).

While currently available depression treatments are generally well tolerated and safe even if you’re being treated
for cancer, possible drug interactions and side effects
require careful monitoring. talk with your health care
provider about the medications you’re taking as well as
other treatment options. for the latest information on
medications, visit the u.s. food and Drug administration
website at http://www.fda.gov. not everyone responds
to treatment the same way. medications can take several
weeks to work, may need to be combined with ongoing
talk therapy, or may need to be changed or adjusted to
minimize side effects and achieve the best results.
along with cBt, additional forms of talk therapy have
been shown to help people with cancer manage their
depression, including4:
n

psychoeducation, which teaches you about your illness
and its treatment

n

stress management training, which teaches you different ways to cope with anxiety

n

problem-solving therapy, which can help you identify
problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve
those problems.

You can also join a support group, which provides an
important outlet for sharing the difficult emotions you’re
feeling. You can learn how to cope with your depression and your cancer from others who are going through
similar experiences.
more information about depression treatments can be
found on the nimH website at http://www.nimh.nih.
gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed
or know someone who is, don’t lose hope. seek help for
depression.
National Institute of Mental Health

For More Information on Depression

Citations

Reprints

visit the national library of medicine’s
medlineplus http://medlineplus.gov
en español http://medlineplus.gov/spanish

1. Kessler rc, chiu Wt, Demler o, merikangas Kr,
Walters ee. prevalence, severity, and comorbidity of
12-month Dsm-iv disorders in the national
comorbidity survey replication. Arch Gen Psychiatry.
2005 Jun; 62(6):617–27.

this publication is in the public domain and may be reproduced
or copied without permission from nimH. We encourage you to
reproduce it and use it in your efforts to improve public health.
citation of the national institute of mental Health as a source
is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use
these guidelines:

for information on clinical trials
http://www.nimh.nih.gov/health/trials/index.shtml
national library of medicine clinical trials database
http://www.clinicaltrials.gov
information from nimH is available in multiple formats. You
can browse online, download documents in pDf, and order
materials through the mail. check the nimH website at
http://www.nimh.nih.gov for the latest information on
this topic and to order publications. if you do not have
internet access please contact the nimH information
resource center at the numbers listed below.
National Institute of Mental Health
science Writing, press & Dissemination Branch
6001 executive Boulevard
room 8184, msc 9663
Bethesda, mD 20892-9663
phone: 301-443-4513 or
1-866-615-nimH (6464) toll-free
ttY: 301-443-8431 or
1-866-415-8051 toll-free
faX: 301-443-4279
e-mail: nimhinfo@nih.gov
Website: http://www.nimh.nih.gov

2. Williams s, Dale J. the effectiveness of treatment for
depression/depressive symptoms in adults with cancer:
a systematic review. British Journal of Cancer. 2006
feb 13; 94(3):372–90.
3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer
incidence and survival? Nature Clinical Practice:
Oncology. 2008 aug; 5(8):466–75.
4. Jacobsen pB, Jim Hs. psychosocial interventions for
anxiety and depression in adult cancer patients:
achievements and challenges. CA: A Cancer Journal for
Clinicians. 2008 Jul–aug; 58(4):214–30.

	 nimH does not endorse or recommend any commercial prod-

n

ucts, processes, or services, and our publications may not be
used for advertising or endorsement purposes.

	 nimH does not provide specific medical advice or treatment

n

recommendations or referrals; our materials may not be used
in a manner that has the appearance of such information.

	 nimH requests that non-federal organizations not alter our

n

publications in ways that will jeopardize the integrity and
“brand” when using the publication.

	 addition of non-federal Government logos and website links

n

may not have the appearance of nimH endorsement of any
specific commercial products or services or medical treatments or services.
if you have questions regarding these guidelines and use of nimH
publications, please contact the nimH information resource
center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov.

For More Information on Cancer
National Cancer Institute
office of communications and education/
public inquiries office
6116 executive Boulevard, suite 300
Bethesda, mD 20892-8322
phone: 1-800-4-cancer (1-800-422-6237)
e-mail: http://www.cancer.gov/contact
Website: http://www.cancer.gov

u.s. Department of HealtH anD Human services
national institutes of Health
national institute of mental Health
niH publication no. 11–5002
revised 2011

Depression and
Cancer
National Institute of Mental Health

For More Information on Depression

Citations

Reprints

visit the national library of medicine’s
medlineplus http://medlineplus.gov
en español http://medlineplus.gov/spanish

1. Kessler rc, chiu Wt, Demler o, merikangas Kr,
Walters ee. prevalence, severity, and comorbidity of
12-month Dsm-iv disorders in the national
comorbidity survey replication. Arch Gen Psychiatry.
2005 Jun; 62(6):617–27.

this publication is in the public domain and may be reproduced
or copied without permission from nimH. We encourage you to
reproduce it and use it in your efforts to improve public health.
citation of the national institute of mental Health as a source
is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use
these guidelines:

for information on clinical trials
http://www.nimh.nih.gov/health/trials/index.shtml
national library of medicine clinical trials database
http://www.clinicaltrials.gov
information from nimH is available in multiple formats. You
can browse online, download documents in pDf, and order
materials through the mail. check the nimH website at
http://www.nimh.nih.gov for the latest information on
this topic and to order publications. if you do not have
internet access please contact the nimH information
resource center at the numbers listed below.
National Institute of Mental Health
science Writing, press & Dissemination Branch
6001 executive Boulevard
room 8184, msc 9663
Bethesda, mD 20892-9663
phone: 301-443-4513 or
1-866-615-nimH (6464) toll-free
ttY: 301-443-8431 or
1-866-415-8051 toll-free
faX: 301-443-4279
e-mail: nimhinfo@nih.gov
Website: http://www.nimh.nih.gov

2. Williams s, Dale J. the effectiveness of treatment for
depression/depressive symptoms in adults with cancer:
a systematic review. British Journal of Cancer. 2006
feb 13; 94(3):372–90.
3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer
incidence and survival? Nature Clinical Practice:
Oncology. 2008 aug; 5(8):466–75.
4. Jacobsen pB, Jim Hs. psychosocial interventions for
anxiety and depression in adult cancer patients:
achievements and challenges. CA: A Cancer Journal for
Clinicians. 2008 Jul–aug; 58(4):214–30.

	 nimH does not endorse or recommend any commercial prod-

n

ucts, processes, or services, and our publications may not be
used for advertising or endorsement purposes.

	 nimH does not provide specific medical advice or treatment

n

recommendations or referrals; our materials may not be used
in a manner that has the appearance of such information.

	 nimH requests that non-federal organizations not alter our

n

publications in ways that will jeopardize the integrity and
“brand” when using the publication.

	 addition of non-federal Government logos and website links

n

may not have the appearance of nimH endorsement of any
specific commercial products or services or medical treatments or services.
if you have questions regarding these guidelines and use of nimH
publications, please contact the nimH information resource
center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov.

For More Information on Cancer
National Cancer Institute
office of communications and education/
public inquiries office
6116 executive Boulevard, suite 300
Bethesda, mD 20892-8322
phone: 1-800-4-cancer (1-800-422-6237)
e-mail: http://www.cancer.gov/contact
Website: http://www.cancer.gov

u.s. Department of HealtH anD Human services
national institutes of Health
national institute of mental Health
niH publication no. 11–5002
revised 2011

Depression and
Cancer
National Institute of Mental Health

For More Information on Depression

Citations

Reprints

visit the national library of medicine’s
medlineplus http://medlineplus.gov
en español http://medlineplus.gov/spanish

1. Kessler rc, chiu Wt, Demler o, merikangas Kr,
Walters ee. prevalence, severity, and comorbidity of
12-month Dsm-iv disorders in the national
comorbidity survey replication. Arch Gen Psychiatry.
2005 Jun; 62(6):617–27.

this publication is in the public domain and may be reproduced
or copied without permission from nimH. We encourage you to
reproduce it and use it in your efforts to improve public health.
citation of the national institute of mental Health as a source
is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use
these guidelines:

for information on clinical trials
http://www.nimh.nih.gov/health/trials/index.shtml
national library of medicine clinical trials database
http://www.clinicaltrials.gov
information from nimH is available in multiple formats. You
can browse online, download documents in pDf, and order
materials through the mail. check the nimH website at
http://www.nimh.nih.gov for the latest information on
this topic and to order publications. if you do not have
internet access please contact the nimH information
resource center at the numbers listed below.
National Institute of Mental Health
science Writing, press & Dissemination Branch
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phone: 301-443-4513 or
1-866-615-nimH (6464) toll-free
ttY: 301-443-8431 or
1-866-415-8051 toll-free
faX: 301-443-4279
e-mail: nimhinfo@nih.gov
Website: http://www.nimh.nih.gov

2. Williams s, Dale J. the effectiveness of treatment for
depression/depressive symptoms in adults with cancer:
a systematic review. British Journal of Cancer. 2006
feb 13; 94(3):372–90.
3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer
incidence and survival? Nature Clinical Practice:
Oncology. 2008 aug; 5(8):466–75.
4. Jacobsen pB, Jim Hs. psychosocial interventions for
anxiety and depression in adult cancer patients:
achievements and challenges. CA: A Cancer Journal for
Clinicians. 2008 Jul–aug; 58(4):214–30.

	 nimH does not endorse or recommend any commercial prod-

n

ucts, processes, or services, and our publications may not be
used for advertising or endorsement purposes.

	 nimH does not provide specific medical advice or treatment

n

recommendations or referrals; our materials may not be used
in a manner that has the appearance of such information.

	 nimH requests that non-federal organizations not alter our

n

publications in ways that will jeopardize the integrity and
“brand” when using the publication.

	 addition of non-federal Government logos and website links

n

may not have the appearance of nimH endorsement of any
specific commercial products or services or medical treatments or services.
if you have questions regarding these guidelines and use of nimH
publications, please contact the nimH information resource
center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov.

For More Information on Cancer
National Cancer Institute
office of communications and education/
public inquiries office
6116 executive Boulevard, suite 300
Bethesda, mD 20892-8322
phone: 1-800-4-cancer (1-800-422-6237)
e-mail: http://www.cancer.gov/contact
Website: http://www.cancer.gov

u.s. Department of HealtH anD Human services
national institutes of Health
national institute of mental Health
niH publication no. 11–5002
revised 2011

Depression and
Cancer

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Global Medical Cures™ | Depression and Cancer

  • 1. National Institute of Mental Health For More Information on Depression Citations Reprints visit the national library of medicine’s medlineplus http://medlineplus.gov en español http://medlineplus.gov/spanish 1. Kessler rc, chiu Wt, Demler o, merikangas Kr, Walters ee. prevalence, severity, and comorbidity of 12-month Dsm-iv disorders in the national comorbidity survey replication. Arch Gen Psychiatry. 2005 Jun; 62(6):617–27. this publication is in the public domain and may be reproduced or copied without permission from nimH. We encourage you to reproduce it and use it in your efforts to improve public health. citation of the national institute of mental Health as a source is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use these guidelines: for information on clinical trials http://www.nimh.nih.gov/health/trials/index.shtml national library of medicine clinical trials database http://www.clinicaltrials.gov information from nimH is available in multiple formats. You can browse online, download documents in pDf, and order materials through the mail. check the nimH website at http://www.nimh.nih.gov for the latest information on this topic and to order publications. if you do not have internet access please contact the nimH information resource center at the numbers listed below. National Institute of Mental Health science Writing, press & Dissemination Branch 6001 executive Boulevard room 8184, msc 9663 Bethesda, mD 20892-9663 phone: 301-443-4513 or 1-866-615-nimH (6464) toll-free ttY: 301-443-8431 or 1-866-415-8051 toll-free faX: 301-443-4279 e-mail: nimhinfo@nih.gov Website: http://www.nimh.nih.gov 2. Williams s, Dale J. the effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review. British Journal of Cancer. 2006 feb 13; 94(3):372–90. 3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer incidence and survival? Nature Clinical Practice: Oncology. 2008 aug; 5(8):466–75. 4. Jacobsen pB, Jim Hs. psychosocial interventions for anxiety and depression in adult cancer patients: achievements and challenges. CA: A Cancer Journal for Clinicians. 2008 Jul–aug; 58(4):214–30. nimH does not endorse or recommend any commercial prod- n ucts, processes, or services, and our publications may not be used for advertising or endorsement purposes. nimH does not provide specific medical advice or treatment n recommendations or referrals; our materials may not be used in a manner that has the appearance of such information. nimH requests that non-federal organizations not alter our n publications in ways that will jeopardize the integrity and “brand” when using the publication. addition of non-federal Government logos and website links n may not have the appearance of nimH endorsement of any specific commercial products or services or medical treatments or services. if you have questions regarding these guidelines and use of nimH publications, please contact the nimH information resource center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov. For More Information on Cancer National Cancer Institute office of communications and education/ public inquiries office 6116 executive Boulevard, suite 300 Bethesda, mD 20892-8322 phone: 1-800-4-cancer (1-800-422-6237) e-mail: http://www.cancer.gov/contact Website: http://www.cancer.gov u.s. Department of HealtH anD Human services national institutes of Health national institute of mental Health niH publication no. 11–5002 revised 2011 Depression and Cancer
  • 2. D epression not only affects your brain and behavior— it affects your entire body. Depression has been linked with other health problems, including cancer. Dealing with more than one health problem at a time can be difficult, so proper treatment is important. What is depression? major depressive disorder, or depression, is a serious mental illness. Depression interferes with your daily life and routine and reduces your quality of life. about 6.7 percent of u.s. adults ages 18 and older have depression.1 Signs and Symptoms of Depression n ongoing sad, anxious, or empty feelings n feeling hopeless n feeling guilty, worthless, or helpless n feeling irritable or restless n loss of interest in activities or hobbies once enjoyable, including sex n feeling tired all the time n Difficulty concentrating, remembering details, or making decisions n Difficulty falling asleep or staying asleep, a condition called insomnia, or sleeping all the time n overeating or loss of appetite n thoughts of death and suicide or suicide attempts n ongoing aches and pains, headaches, cramps, or digestive problems that do not ease with treatment. for more information, see the nimH booklet on Depression at http://www.nimh.nih.gov/health/publications/depression/ index.shtml. What is cancer? cancer is a disease that develops when abnormal cells in your body divide and multiply without control. normally, cells grow and divide to produce more cells only when your body needs them. But sometimes, cells keep dividing when new cells are not needed. these extra cells may form a mass called a tumor. tumors can be either benign, which means not cancerous, or malignant, which is cancerous. cancer cells can develop anywhere in the body and can spread to other body parts through your blood and lymph systems. lymph is a clear fluid that carries blood cells that fight infection and disease throughout the body. lymph travels through a system of vessels, much like blood vessels. cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer and symptoms can vary greatly depending on the location, or the organs and tissue that are affected. How are depression and cancer linked? Depression is not regularly linked with cancer, and there is no proof that one disease causes the other.2,3 However, when faced with a diagnosis of cancer, you may feel extreme stress, anger, sadness, or a number of other strong emotions. While these feelings usually lessen over time, they can develop into depression. if you develop depression after learning you have cancer—or were depressed before your diagnosis—your depression may affect the course of your cancer2,3 as well as your ability to take part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment. How is depression treated in people who have cancer? Depression is diagnosed and treated by a health care provider. treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective. at present, the most common treatments for depression include: n cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative thinking styles and behaviors that may contribute to their depression n selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa), sertraline (Zoloft), and fluoxetine (prozac) n serotonin and norepinephrine reuptake inhibitor (snri), a type of antidepressant medication similar to ssri that includes venlafaxine (effexor) and duloxetine (cymbalta). While currently available depression treatments are generally well tolerated and safe even if you’re being treated for cancer, possible drug interactions and side effects require careful monitoring. talk with your health care provider about the medications you’re taking as well as other treatment options. for the latest information on medications, visit the u.s. food and Drug administration website at http://www.fda.gov. not everyone responds to treatment the same way. medications can take several weeks to work, may need to be combined with ongoing talk therapy, or may need to be changed or adjusted to minimize side effects and achieve the best results. along with cBt, additional forms of talk therapy have been shown to help people with cancer manage their depression, including4: n psychoeducation, which teaches you about your illness and its treatment n stress management training, which teaches you different ways to cope with anxiety n problem-solving therapy, which can help you identify problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve those problems. You can also join a support group, which provides an important outlet for sharing the difficult emotions you’re feeling. You can learn how to cope with your depression and your cancer from others who are going through similar experiences. more information about depression treatments can be found on the nimH website at http://www.nimh.nih. gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed or know someone who is, don’t lose hope. seek help for depression.
  • 3. D epression not only affects your brain and behavior— it affects your entire body. Depression has been linked with other health problems, including cancer. Dealing with more than one health problem at a time can be difficult, so proper treatment is important. What is depression? major depressive disorder, or depression, is a serious mental illness. Depression interferes with your daily life and routine and reduces your quality of life. about 6.7 percent of u.s. adults ages 18 and older have depression.1 Signs and Symptoms of Depression n ongoing sad, anxious, or empty feelings n feeling hopeless n feeling guilty, worthless, or helpless n feeling irritable or restless n loss of interest in activities or hobbies once enjoyable, including sex n feeling tired all the time n Difficulty concentrating, remembering details, or making decisions n Difficulty falling asleep or staying asleep, a condition called insomnia, or sleeping all the time n overeating or loss of appetite n thoughts of death and suicide or suicide attempts n ongoing aches and pains, headaches, cramps, or digestive problems that do not ease with treatment. for more information, see the nimH booklet on Depression at http://www.nimh.nih.gov/health/publications/depression/ index.shtml. What is cancer? cancer is a disease that develops when abnormal cells in your body divide and multiply without control. normally, cells grow and divide to produce more cells only when your body needs them. But sometimes, cells keep dividing when new cells are not needed. these extra cells may form a mass called a tumor. tumors can be either benign, which means not cancerous, or malignant, which is cancerous. cancer cells can develop anywhere in the body and can spread to other body parts through your blood and lymph systems. lymph is a clear fluid that carries blood cells that fight infection and disease throughout the body. lymph travels through a system of vessels, much like blood vessels. cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer and symptoms can vary greatly depending on the location, or the organs and tissue that are affected. How are depression and cancer linked? Depression is not regularly linked with cancer, and there is no proof that one disease causes the other.2,3 However, when faced with a diagnosis of cancer, you may feel extreme stress, anger, sadness, or a number of other strong emotions. While these feelings usually lessen over time, they can develop into depression. if you develop depression after learning you have cancer—or were depressed before your diagnosis—your depression may affect the course of your cancer2,3 as well as your ability to take part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment. How is depression treated in people who have cancer? Depression is diagnosed and treated by a health care provider. treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective. at present, the most common treatments for depression include: n cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative thinking styles and behaviors that may contribute to their depression n selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa), sertraline (Zoloft), and fluoxetine (prozac) n serotonin and norepinephrine reuptake inhibitor (snri), a type of antidepressant medication similar to ssri that includes venlafaxine (effexor) and duloxetine (cymbalta). While currently available depression treatments are generally well tolerated and safe even if you’re being treated for cancer, possible drug interactions and side effects require careful monitoring. talk with your health care provider about the medications you’re taking as well as other treatment options. for the latest information on medications, visit the u.s. food and Drug administration website at http://www.fda.gov. not everyone responds to treatment the same way. medications can take several weeks to work, may need to be combined with ongoing talk therapy, or may need to be changed or adjusted to minimize side effects and achieve the best results. along with cBt, additional forms of talk therapy have been shown to help people with cancer manage their depression, including4: n psychoeducation, which teaches you about your illness and its treatment n stress management training, which teaches you different ways to cope with anxiety n problem-solving therapy, which can help you identify problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve those problems. You can also join a support group, which provides an important outlet for sharing the difficult emotions you’re feeling. You can learn how to cope with your depression and your cancer from others who are going through similar experiences. more information about depression treatments can be found on the nimH website at http://www.nimh.nih. gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed or know someone who is, don’t lose hope. seek help for depression.
  • 4. D epression not only affects your brain and behavior— it affects your entire body. Depression has been linked with other health problems, including cancer. Dealing with more than one health problem at a time can be difficult, so proper treatment is important. What is depression? major depressive disorder, or depression, is a serious mental illness. Depression interferes with your daily life and routine and reduces your quality of life. about 6.7 percent of u.s. adults ages 18 and older have depression.1 Signs and Symptoms of Depression n ongoing sad, anxious, or empty feelings n feeling hopeless n feeling guilty, worthless, or helpless n feeling irritable or restless n loss of interest in activities or hobbies once enjoyable, including sex n feeling tired all the time n Difficulty concentrating, remembering details, or making decisions n Difficulty falling asleep or staying asleep, a condition called insomnia, or sleeping all the time n overeating or loss of appetite n thoughts of death and suicide or suicide attempts n ongoing aches and pains, headaches, cramps, or digestive problems that do not ease with treatment. for more information, see the nimH booklet on Depression at http://www.nimh.nih.gov/health/publications/depression/ index.shtml. What is cancer? cancer is a disease that develops when abnormal cells in your body divide and multiply without control. normally, cells grow and divide to produce more cells only when your body needs them. But sometimes, cells keep dividing when new cells are not needed. these extra cells may form a mass called a tumor. tumors can be either benign, which means not cancerous, or malignant, which is cancerous. cancer cells can develop anywhere in the body and can spread to other body parts through your blood and lymph systems. lymph is a clear fluid that carries blood cells that fight infection and disease throughout the body. lymph travels through a system of vessels, much like blood vessels. cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer and symptoms can vary greatly depending on the location, or the organs and tissue that are affected. How are depression and cancer linked? Depression is not regularly linked with cancer, and there is no proof that one disease causes the other.2,3 However, when faced with a diagnosis of cancer, you may feel extreme stress, anger, sadness, or a number of other strong emotions. While these feelings usually lessen over time, they can develop into depression. if you develop depression after learning you have cancer—or were depressed before your diagnosis—your depression may affect the course of your cancer2,3 as well as your ability to take part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment. How is depression treated in people who have cancer? Depression is diagnosed and treated by a health care provider. treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective. at present, the most common treatments for depression include: n cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative thinking styles and behaviors that may contribute to their depression n selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa), sertraline (Zoloft), and fluoxetine (prozac) n serotonin and norepinephrine reuptake inhibitor (snri), a type of antidepressant medication similar to ssri that includes venlafaxine (effexor) and duloxetine (cymbalta). While currently available depression treatments are generally well tolerated and safe even if you’re being treated for cancer, possible drug interactions and side effects require careful monitoring. talk with your health care provider about the medications you’re taking as well as other treatment options. for the latest information on medications, visit the u.s. food and Drug administration website at http://www.fda.gov. not everyone responds to treatment the same way. medications can take several weeks to work, may need to be combined with ongoing talk therapy, or may need to be changed or adjusted to minimize side effects and achieve the best results. along with cBt, additional forms of talk therapy have been shown to help people with cancer manage their depression, including4: n psychoeducation, which teaches you about your illness and its treatment n stress management training, which teaches you different ways to cope with anxiety n problem-solving therapy, which can help you identify problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve those problems. You can also join a support group, which provides an important outlet for sharing the difficult emotions you’re feeling. You can learn how to cope with your depression and your cancer from others who are going through similar experiences. more information about depression treatments can be found on the nimH website at http://www.nimh.nih. gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed or know someone who is, don’t lose hope. seek help for depression.
  • 5. D epression not only affects your brain and behavior— it affects your entire body. Depression has been linked with other health problems, including cancer. Dealing with more than one health problem at a time can be difficult, so proper treatment is important. What is depression? major depressive disorder, or depression, is a serious mental illness. Depression interferes with your daily life and routine and reduces your quality of life. about 6.7 percent of u.s. adults ages 18 and older have depression.1 Signs and Symptoms of Depression n ongoing sad, anxious, or empty feelings n feeling hopeless n feeling guilty, worthless, or helpless n feeling irritable or restless n loss of interest in activities or hobbies once enjoyable, including sex n feeling tired all the time n Difficulty concentrating, remembering details, or making decisions n Difficulty falling asleep or staying asleep, a condition called insomnia, or sleeping all the time n overeating or loss of appetite n thoughts of death and suicide or suicide attempts n ongoing aches and pains, headaches, cramps, or digestive problems that do not ease with treatment. for more information, see the nimH booklet on Depression at http://www.nimh.nih.gov/health/publications/depression/ index.shtml. What is cancer? cancer is a disease that develops when abnormal cells in your body divide and multiply without control. normally, cells grow and divide to produce more cells only when your body needs them. But sometimes, cells keep dividing when new cells are not needed. these extra cells may form a mass called a tumor. tumors can be either benign, which means not cancerous, or malignant, which is cancerous. cancer cells can develop anywhere in the body and can spread to other body parts through your blood and lymph systems. lymph is a clear fluid that carries blood cells that fight infection and disease throughout the body. lymph travels through a system of vessels, much like blood vessels. cancer cells damage the organs and tissues they invade, causing a variety of symptoms. there are different types of cancer and symptoms can vary greatly depending on the location, or the organs and tissue that are affected. How are depression and cancer linked? Depression is not regularly linked with cancer, and there is no proof that one disease causes the other.2,3 However, when faced with a diagnosis of cancer, you may feel extreme stress, anger, sadness, or a number of other strong emotions. While these feelings usually lessen over time, they can develop into depression. if you develop depression after learning you have cancer—or were depressed before your diagnosis—your depression may affect the course of your cancer2,3 as well as your ability to take part in treatment. it is important for you to treat your depression even if you are undergoing complicated cancer treatment. How is depression treated in people who have cancer? Depression is diagnosed and treated by a health care provider. treating depression can help you manage your cancer treatment and improve your overall health. recovery from depression takes time but treatments are effective. at present, the most common treatments for depression include: n cognitive behavioral therapy (cBt), a type of psychotherapy, or talk therapy, that helps people change negative thinking styles and behaviors that may contribute to their depression n selective serotonin reuptake inhibitor (ssri), a type of antidepressant medication that includes citalopram (celexa), sertraline (Zoloft), and fluoxetine (prozac) n serotonin and norepinephrine reuptake inhibitor (snri), a type of antidepressant medication similar to ssri that includes venlafaxine (effexor) and duloxetine (cymbalta). While currently available depression treatments are generally well tolerated and safe even if you’re being treated for cancer, possible drug interactions and side effects require careful monitoring. talk with your health care provider about the medications you’re taking as well as other treatment options. for the latest information on medications, visit the u.s. food and Drug administration website at http://www.fda.gov. not everyone responds to treatment the same way. medications can take several weeks to work, may need to be combined with ongoing talk therapy, or may need to be changed or adjusted to minimize side effects and achieve the best results. along with cBt, additional forms of talk therapy have been shown to help people with cancer manage their depression, including4: n psychoeducation, which teaches you about your illness and its treatment n stress management training, which teaches you different ways to cope with anxiety n problem-solving therapy, which can help you identify problems that interfere with your daily life and contribute to depressive symptoms and find ways to solve those problems. You can also join a support group, which provides an important outlet for sharing the difficult emotions you’re feeling. You can learn how to cope with your depression and your cancer from others who are going through similar experiences. more information about depression treatments can be found on the nimH website at http://www.nimh.nih. gov/health/publications/depression/how-is-depressiondetected-and-treated.shtml. if you think you are depressed or know someone who is, don’t lose hope. seek help for depression.
  • 6. National Institute of Mental Health For More Information on Depression Citations Reprints visit the national library of medicine’s medlineplus http://medlineplus.gov en español http://medlineplus.gov/spanish 1. Kessler rc, chiu Wt, Demler o, merikangas Kr, Walters ee. prevalence, severity, and comorbidity of 12-month Dsm-iv disorders in the national comorbidity survey replication. Arch Gen Psychiatry. 2005 Jun; 62(6):617–27. this publication is in the public domain and may be reproduced or copied without permission from nimH. We encourage you to reproduce it and use it in your efforts to improve public health. citation of the national institute of mental Health as a source is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use these guidelines: for information on clinical trials http://www.nimh.nih.gov/health/trials/index.shtml national library of medicine clinical trials database http://www.clinicaltrials.gov information from nimH is available in multiple formats. You can browse online, download documents in pDf, and order materials through the mail. check the nimH website at http://www.nimh.nih.gov for the latest information on this topic and to order publications. if you do not have internet access please contact the nimH information resource center at the numbers listed below. National Institute of Mental Health science Writing, press & Dissemination Branch 6001 executive Boulevard room 8184, msc 9663 Bethesda, mD 20892-9663 phone: 301-443-4513 or 1-866-615-nimH (6464) toll-free ttY: 301-443-8431 or 1-866-415-8051 toll-free faX: 301-443-4279 e-mail: nimhinfo@nih.gov Website: http://www.nimh.nih.gov 2. Williams s, Dale J. the effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review. British Journal of Cancer. 2006 feb 13; 94(3):372–90. 3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer incidence and survival? Nature Clinical Practice: Oncology. 2008 aug; 5(8):466–75. 4. Jacobsen pB, Jim Hs. psychosocial interventions for anxiety and depression in adult cancer patients: achievements and challenges. CA: A Cancer Journal for Clinicians. 2008 Jul–aug; 58(4):214–30. nimH does not endorse or recommend any commercial prod- n ucts, processes, or services, and our publications may not be used for advertising or endorsement purposes. nimH does not provide specific medical advice or treatment n recommendations or referrals; our materials may not be used in a manner that has the appearance of such information. nimH requests that non-federal organizations not alter our n publications in ways that will jeopardize the integrity and “brand” when using the publication. addition of non-federal Government logos and website links n may not have the appearance of nimH endorsement of any specific commercial products or services or medical treatments or services. if you have questions regarding these guidelines and use of nimH publications, please contact the nimH information resource center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov. For More Information on Cancer National Cancer Institute office of communications and education/ public inquiries office 6116 executive Boulevard, suite 300 Bethesda, mD 20892-8322 phone: 1-800-4-cancer (1-800-422-6237) e-mail: http://www.cancer.gov/contact Website: http://www.cancer.gov u.s. Department of HealtH anD Human services national institutes of Health national institute of mental Health niH publication no. 11–5002 revised 2011 Depression and Cancer
  • 7. National Institute of Mental Health For More Information on Depression Citations Reprints visit the national library of medicine’s medlineplus http://medlineplus.gov en español http://medlineplus.gov/spanish 1. Kessler rc, chiu Wt, Demler o, merikangas Kr, Walters ee. prevalence, severity, and comorbidity of 12-month Dsm-iv disorders in the national comorbidity survey replication. Arch Gen Psychiatry. 2005 Jun; 62(6):617–27. this publication is in the public domain and may be reproduced or copied without permission from nimH. We encourage you to reproduce it and use it in your efforts to improve public health. citation of the national institute of mental Health as a source is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use these guidelines: for information on clinical trials http://www.nimh.nih.gov/health/trials/index.shtml national library of medicine clinical trials database http://www.clinicaltrials.gov information from nimH is available in multiple formats. You can browse online, download documents in pDf, and order materials through the mail. check the nimH website at http://www.nimh.nih.gov for the latest information on this topic and to order publications. if you do not have internet access please contact the nimH information resource center at the numbers listed below. National Institute of Mental Health science Writing, press & Dissemination Branch 6001 executive Boulevard room 8184, msc 9663 Bethesda, mD 20892-9663 phone: 301-443-4513 or 1-866-615-nimH (6464) toll-free ttY: 301-443-8431 or 1-866-415-8051 toll-free faX: 301-443-4279 e-mail: nimhinfo@nih.gov Website: http://www.nimh.nih.gov 2. Williams s, Dale J. the effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review. British Journal of Cancer. 2006 feb 13; 94(3):372–90. 3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer incidence and survival? Nature Clinical Practice: Oncology. 2008 aug; 5(8):466–75. 4. Jacobsen pB, Jim Hs. psychosocial interventions for anxiety and depression in adult cancer patients: achievements and challenges. CA: A Cancer Journal for Clinicians. 2008 Jul–aug; 58(4):214–30. nimH does not endorse or recommend any commercial prod- n ucts, processes, or services, and our publications may not be used for advertising or endorsement purposes. nimH does not provide specific medical advice or treatment n recommendations or referrals; our materials may not be used in a manner that has the appearance of such information. nimH requests that non-federal organizations not alter our n publications in ways that will jeopardize the integrity and “brand” when using the publication. addition of non-federal Government logos and website links n may not have the appearance of nimH endorsement of any specific commercial products or services or medical treatments or services. if you have questions regarding these guidelines and use of nimH publications, please contact the nimH information resource center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov. For More Information on Cancer National Cancer Institute office of communications and education/ public inquiries office 6116 executive Boulevard, suite 300 Bethesda, mD 20892-8322 phone: 1-800-4-cancer (1-800-422-6237) e-mail: http://www.cancer.gov/contact Website: http://www.cancer.gov u.s. Department of HealtH anD Human services national institutes of Health national institute of mental Health niH publication no. 11–5002 revised 2011 Depression and Cancer
  • 8. National Institute of Mental Health For More Information on Depression Citations Reprints visit the national library of medicine’s medlineplus http://medlineplus.gov en español http://medlineplus.gov/spanish 1. Kessler rc, chiu Wt, Demler o, merikangas Kr, Walters ee. prevalence, severity, and comorbidity of 12-month Dsm-iv disorders in the national comorbidity survey replication. Arch Gen Psychiatry. 2005 Jun; 62(6):617–27. this publication is in the public domain and may be reproduced or copied without permission from nimH. We encourage you to reproduce it and use it in your efforts to improve public health. citation of the national institute of mental Health as a source is appreciated. However, using government materials inappropriately can raise legal or ethical concerns, so we ask you to use these guidelines: for information on clinical trials http://www.nimh.nih.gov/health/trials/index.shtml national library of medicine clinical trials database http://www.clinicaltrials.gov information from nimH is available in multiple formats. You can browse online, download documents in pDf, and order materials through the mail. check the nimH website at http://www.nimh.nih.gov for the latest information on this topic and to order publications. if you do not have internet access please contact the nimH information resource center at the numbers listed below. National Institute of Mental Health science Writing, press & Dissemination Branch 6001 executive Boulevard room 8184, msc 9663 Bethesda, mD 20892-9663 phone: 301-443-4513 or 1-866-615-nimH (6464) toll-free ttY: 301-443-8431 or 1-866-415-8051 toll-free faX: 301-443-4279 e-mail: nimhinfo@nih.gov Website: http://www.nimh.nih.gov 2. Williams s, Dale J. the effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review. British Journal of Cancer. 2006 feb 13; 94(3):372–90. 3. chida Y, Hamer m, Wardle J, steptoe a. Do stressrelated psychosocial factors contribute to cancer incidence and survival? Nature Clinical Practice: Oncology. 2008 aug; 5(8):466–75. 4. Jacobsen pB, Jim Hs. psychosocial interventions for anxiety and depression in adult cancer patients: achievements and challenges. CA: A Cancer Journal for Clinicians. 2008 Jul–aug; 58(4):214–30. nimH does not endorse or recommend any commercial prod- n ucts, processes, or services, and our publications may not be used for advertising or endorsement purposes. nimH does not provide specific medical advice or treatment n recommendations or referrals; our materials may not be used in a manner that has the appearance of such information. nimH requests that non-federal organizations not alter our n publications in ways that will jeopardize the integrity and “brand” when using the publication. addition of non-federal Government logos and website links n may not have the appearance of nimH endorsement of any specific commercial products or services or medical treatments or services. if you have questions regarding these guidelines and use of nimH publications, please contact the nimH information resource center at 1-866-615-6464 or e-mail at nimhinfo@nih.gov. For More Information on Cancer National Cancer Institute office of communications and education/ public inquiries office 6116 executive Boulevard, suite 300 Bethesda, mD 20892-8322 phone: 1-800-4-cancer (1-800-422-6237) e-mail: http://www.cancer.gov/contact Website: http://www.cancer.gov u.s. Department of HealtH anD Human services national institutes of Health national institute of mental Health niH publication no. 11–5002 revised 2011 Depression and Cancer