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Cost-effectiveness of a trap to
capture the dengue adult vector in
 the context of the Public Health
         System in Brazil
Authors: Fabiana Raynal Floriano; Luis Eugenio Portela; Sebastião Loureiro;
Martha Teixeira; Gimena M. Santos; Vanessa C.G.S. Morato; Maria da Glória
Teixeira; Patrícia Barber; Naomar de Almeida Filho
Figure 2: Dengue incidence between 2001 and 2011 in Salvador, Bahia and Brazil.
 Introduction
Figure 1: Distribution of Dengue around the world, 2005.




                                         Source: http://www2.datasus.gov.br/DATASUS/index.php




Source: http://www.cdc.gov/ncidod/dvbid/dengue/map-distribution-2005.htm
Introduction
 Dengue’s impact on health services, society and
  country’s economy.
 National Dengue Control Plan (PNCD) (Ministry of
  Health, 2002).
 Strategies to eliminate the Aedes aegypti with
  controversial efficacy    new technologies are being
  developed and applied.
 Mosquitrap - letal (Intelligent Monitoring System)


                                                                 Source:
                                                  http://www.ecovec.com/
                                                           midengue.php
Objective
 To estimate the cost-effectiveness of:

   Trap to capture the dengue adult vector+
    Usual program (Intervention area)

   Usual program of dengue control (Control
    area).
Materials and Method
 Time horizon: 2011;
 Public Health System perspective: direct medical
  costs
 Population: children aged 0-14 years
 Epidemiological indicators:
   incidence;
   percentage distribution of dengue according to
    dengue severity.
 Trap Effectiveness measure: Reduction of the
  dengue incidence
Materials and Method - Costs
Health Care Cost
 All stages of the disease progression (MH, 2011)
 Direct medical costs: diagnostic tests; drugs; service:
  professional fees and hospitalization
Materials and Method - Costs
Health Care Cost
 All stages of the disease progression (MH, 2011)
 Direct medical costs: diagnostic tests; drugs; service:
  professional fees and hospitalization
Technology Cost
 3,232 traps
 deployment service
 monitoring and maintenance services: materials and
  training
Materials and Method - Costs
Health Care Cost
 All stages of the disease progression (MH, 2011)
 Direct medical costs: diagnostic tests; drugs; service:
  professional fees and hospitalization
Technology Cost
 3,232 traps
 deployment service
 monitoring and maintenance services: materials and
  training
Total Cost
 Control Area: Health Care Cost
 Intervention Area: Health Care Cost + Technology
  Cost
Materials and Method
Effectiveness
 Prevented dengue cases

Cost-Effectiveness
 Decision tree analytical model

Sensitivity Analysis
 Effectiveness: highest and lowest dengue incidence,
  in the last five years, in Salvador
Results

Table 1: Total cost (USD) of dengue treatment, according to risk
classification, Salvador, Bahia, Brazil, 2011.


Costs of Health Care      Group A (%)      Group B (%)       Group C (%)        Group D (%)
Direct medical costs
  Diagnostic tests        201.12 (86.67)   487.93 (90.12)   3,478.98(58.37)    4,911.45 (53.36)
  Professional fees
                           11.78 (5.07)     27.26 (5.04)    2,445.69 (41.04)   4,030.96 (43.79)
and Hospitalization
  Drugs                   19.17 (8.26)     26.20 (4.84)      35.13 (0.59)       262.65 (2.85)
Total Cost of Treatment   232.07 (100)     541.40 (100)     5,959.79 (100)     9,205.06 (100)
Results

Table 2: Dengue cases, total cost and cost average case (USD), in the
intervention and control areas, Salvador, Bahia, Brazil, 2011.

                                                        Difference Between
Itens               Intervention Area   Control Area
                                                               Areas
Incidence                12.73%            14.38%             -1.65
Dengue Case              69,533            78,545             -9,012
Treatment Cost        32,773,670.58     37,021,632.60     - 4,247,962.02
Technology Cost       2,770,471.25          0.00           2,770,471.25
Total Cost            35,544,141.83     37,021,632.60     - 1,477,490.77
Cost Average Case        511.19            471.34             39.85
Results
Table 3: Cost-Effectiveness (C/E), Incremental Cost-Effectiveness Ratio
(ICER) and Sensitivity Analysis of control and intervention
areas, Salvador, Bahia, Brazil, 2011.
                           Cost        Effectiveness                                 Effectiveness
Areas                                                   C/E           Cost                            ICER
                           (C)              (E)                                  (Prevented Cases)
        Intervention   35,544,141.83      69,533       511.19
                                                                - 1,477,490.76        -9,012          163.94
        Control        37,021,632.60      78,545       471.34

Sensitivity Analysis
  Highest Incidence
        Intervention   57,118,639.83     115,305       495.37
                                                                - 4,283,720.22        -14,966         286.23
        Control        61,402,360.04     130,217       471.54
  Lowest Incidence
        Intervention   8,357,184.93       11,853       705.07
                                                                2,023,859.75          -1,584         -1,277.68
        Control        6,333,325.19       13,437       471.34
Conclusion

 Trap was effective

 Control area was dominated

 However, the sensitivity analysis showed that
  the ICER varied according to the population’s
  disease incidence

 Health managers must consider dengue
  incidence, before incorporating the trap
Bibliographical References
1. BRASIL. Ministério da Saúde. Banco de Dados do Sistema Único de
Saúde – DATASUS. http://www2.datasus.gov.br/DATASUS/index.php.
2. BRASIL. Ministério da Saúde. Programa Nacional de Controle da
Dengue. MS, FUNASA. Brasília: Ministério da Saúde, 2002. 34p.
3. SIGTAP. http://sigtap.datasus.gov.br/tabela-unificada/app/sec/inicio.jsp.
4.      Banco     de       Preços      do      Ministério     da      Saúde.
http://bps.saude.gov.br/login.cfm.
5. BRASIL. Ministério da Saúde. Dengue: diagnóstico e manejo clínico:
criança. MS, Secretaria de Vigilância em Saúde, Departamento de
Vigilância Epidemiológica. – Brasília: Ministério da Saúde, 2011. 52p.
6. BRASIL. Instituto Brasileiro de Geografia e Estatística – IBGE.
http://www.ibge.gov.br/home/.
7.      BRASIL.      Banco       Central.    Taxa           de      Câmbio.
http://www4.bcb.gov.br/pec/conversao/conversao.asp.
8. ECOVEC. M.I. Dengue. http://www.ecovec.com/midengue.php.
Contacts:
 fabianaraynal@hotmail.com

           Web site:
  http://www.inct-citecs.ufba.br

http://www.isc.ufba.br/index.php

http://www.pbct.inweb.org.br/pbct/

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Cost-effectiveness of a trap to capture the dengue adult vector in the context of the Public Health System in Brazil. Fabiana Floriano.

  • 1. Cost-effectiveness of a trap to capture the dengue adult vector in the context of the Public Health System in Brazil Authors: Fabiana Raynal Floriano; Luis Eugenio Portela; Sebastião Loureiro; Martha Teixeira; Gimena M. Santos; Vanessa C.G.S. Morato; Maria da Glória Teixeira; Patrícia Barber; Naomar de Almeida Filho
  • 2. Figure 2: Dengue incidence between 2001 and 2011 in Salvador, Bahia and Brazil. Introduction Figure 1: Distribution of Dengue around the world, 2005. Source: http://www2.datasus.gov.br/DATASUS/index.php Source: http://www.cdc.gov/ncidod/dvbid/dengue/map-distribution-2005.htm
  • 3. Introduction  Dengue’s impact on health services, society and country’s economy.  National Dengue Control Plan (PNCD) (Ministry of Health, 2002).  Strategies to eliminate the Aedes aegypti with controversial efficacy new technologies are being developed and applied.  Mosquitrap - letal (Intelligent Monitoring System) Source: http://www.ecovec.com/ midengue.php
  • 4. Objective  To estimate the cost-effectiveness of:  Trap to capture the dengue adult vector+ Usual program (Intervention area)  Usual program of dengue control (Control area).
  • 5. Materials and Method  Time horizon: 2011;  Public Health System perspective: direct medical costs  Population: children aged 0-14 years  Epidemiological indicators:  incidence;  percentage distribution of dengue according to dengue severity.  Trap Effectiveness measure: Reduction of the dengue incidence
  • 6. Materials and Method - Costs Health Care Cost  All stages of the disease progression (MH, 2011)  Direct medical costs: diagnostic tests; drugs; service: professional fees and hospitalization
  • 7. Materials and Method - Costs Health Care Cost  All stages of the disease progression (MH, 2011)  Direct medical costs: diagnostic tests; drugs; service: professional fees and hospitalization Technology Cost  3,232 traps  deployment service  monitoring and maintenance services: materials and training
  • 8. Materials and Method - Costs Health Care Cost  All stages of the disease progression (MH, 2011)  Direct medical costs: diagnostic tests; drugs; service: professional fees and hospitalization Technology Cost  3,232 traps  deployment service  monitoring and maintenance services: materials and training Total Cost  Control Area: Health Care Cost  Intervention Area: Health Care Cost + Technology Cost
  • 9. Materials and Method Effectiveness  Prevented dengue cases Cost-Effectiveness  Decision tree analytical model Sensitivity Analysis  Effectiveness: highest and lowest dengue incidence, in the last five years, in Salvador
  • 10. Results Table 1: Total cost (USD) of dengue treatment, according to risk classification, Salvador, Bahia, Brazil, 2011. Costs of Health Care Group A (%) Group B (%) Group C (%) Group D (%) Direct medical costs Diagnostic tests 201.12 (86.67) 487.93 (90.12) 3,478.98(58.37) 4,911.45 (53.36) Professional fees 11.78 (5.07) 27.26 (5.04) 2,445.69 (41.04) 4,030.96 (43.79) and Hospitalization Drugs 19.17 (8.26) 26.20 (4.84) 35.13 (0.59) 262.65 (2.85) Total Cost of Treatment 232.07 (100) 541.40 (100) 5,959.79 (100) 9,205.06 (100)
  • 11. Results Table 2: Dengue cases, total cost and cost average case (USD), in the intervention and control areas, Salvador, Bahia, Brazil, 2011. Difference Between Itens Intervention Area Control Area Areas Incidence 12.73% 14.38% -1.65 Dengue Case 69,533 78,545 -9,012 Treatment Cost 32,773,670.58 37,021,632.60 - 4,247,962.02 Technology Cost 2,770,471.25 0.00 2,770,471.25 Total Cost 35,544,141.83 37,021,632.60 - 1,477,490.77 Cost Average Case 511.19 471.34 39.85
  • 12. Results Table 3: Cost-Effectiveness (C/E), Incremental Cost-Effectiveness Ratio (ICER) and Sensitivity Analysis of control and intervention areas, Salvador, Bahia, Brazil, 2011. Cost Effectiveness Effectiveness Areas C/E Cost ICER (C) (E) (Prevented Cases) Intervention 35,544,141.83 69,533 511.19 - 1,477,490.76 -9,012 163.94 Control 37,021,632.60 78,545 471.34 Sensitivity Analysis Highest Incidence Intervention 57,118,639.83 115,305 495.37 - 4,283,720.22 -14,966 286.23 Control 61,402,360.04 130,217 471.54 Lowest Incidence Intervention 8,357,184.93 11,853 705.07 2,023,859.75 -1,584 -1,277.68 Control 6,333,325.19 13,437 471.34
  • 13. Conclusion  Trap was effective  Control area was dominated  However, the sensitivity analysis showed that the ICER varied according to the population’s disease incidence  Health managers must consider dengue incidence, before incorporating the trap
  • 14. Bibliographical References 1. BRASIL. Ministério da Saúde. Banco de Dados do Sistema Único de Saúde – DATASUS. http://www2.datasus.gov.br/DATASUS/index.php. 2. BRASIL. Ministério da Saúde. Programa Nacional de Controle da Dengue. MS, FUNASA. Brasília: Ministério da Saúde, 2002. 34p. 3. SIGTAP. http://sigtap.datasus.gov.br/tabela-unificada/app/sec/inicio.jsp. 4. Banco de Preços do Ministério da Saúde. http://bps.saude.gov.br/login.cfm. 5. BRASIL. Ministério da Saúde. Dengue: diagnóstico e manejo clínico: criança. MS, Secretaria de Vigilância em Saúde, Departamento de Vigilância Epidemiológica. – Brasília: Ministério da Saúde, 2011. 52p. 6. BRASIL. Instituto Brasileiro de Geografia e Estatística – IBGE. http://www.ibge.gov.br/home/. 7. BRASIL. Banco Central. Taxa de Câmbio. http://www4.bcb.gov.br/pec/conversao/conversao.asp. 8. ECOVEC. M.I. Dengue. http://www.ecovec.com/midengue.php.
  • 15. Contacts: fabianaraynal@hotmail.com Web site: http://www.inct-citecs.ufba.br http://www.isc.ufba.br/index.php http://www.pbct.inweb.org.br/pbct/