Presentation from the winning team, at the Lean Startup Machine event in Washington, D.C. 18-20 November 2011 The team: Andrew Evans, Kevin May, Jenny Wong, ChanMi Park

1. WINNER OF
WASHINGTON, D. C. 18 NOVEMBER 2011
Rob Shenk @ flickr

2. WHAT IS THE PROBLEM?
WE DON’T HAVE ENOUGH DATA
TO ADVANCE MEDICINE

3. PURE RESEARCH PROBLEM
THE CURRENT DATABASE IS
LIKE BINOCULARS TO AN
ASTRONOMER WHEN WE NEED
THE HUBBLE
redrumblefish

4. PHARMA / CRO PROBLEM
WE’RE NOT LOOKING FOR A
CLOWN FISH, WE’RE FINDING
NEMO
permasmirk

5. “Your plans to host a database
of over a million genomes linke
reported and/or clinically anno d to self-
tated phenotypes is an unprec
resource for investigator s. It w edented
ould enable fast-paced pilot st
feasibility testing of initial projec udies or
ts. … Consideration of paid
the data is well within grant aw access to
ard mechanisms.”
to really
Michael E. Berens, Ph.D. "...incredibly exciting and has the potential
ng with
Professor and Director, Cance
r & Cell Biology Division change liv es… I’ll look forward to wor ki
ogresses."
d your team as your venture pr
Translational Genomics Institu
te (TGen) you an
Sean Nolan
Distinguished Engineer
Microsoft Health Solutions
medicine…
"Pfizer is committed to suppor ting a future of precision ts comprised
Platforms that suppor t the ab ility to generate integrated datase
value… The
of clinical and genetic data bring the potential for significant as well
no vel clinical and genetic data assets
potential for such tools to build lopment."
as impact education of provider s and patients merits further deve
Craig Lipset "This is definitely something that Q
uintiles would be interested
Head of Clinical Innovation in… With us being able to link mor
e and more phenotypical
Pfizer characteristics to genotype data, th
is database that Andy is talking
about will be extremely valuable fo
r both potential clinical trial
design and planning as well as exec
ution of CER-type studies that
INDUSTRY
are becoming more and more popu
lar on the payer side."
John Jones
Practice Lead, IT Strategy & Implem
entation
INTERESTS
Quintiles

7. LET THE GAMES BEGIN!
300+ MILLION ACTIVE GAMERS
LACK OF CUSTOMIZATION
VIRTUAL GOODS MARKET

8. OUR SOLUTION
Willing to solve genome problems through gamification
Incentivize participants using virtual currency
Pharmaceutical companies are willing to pay for data

9. HYPOTHESES
WE CAN STEAL USERS FROM 23ANDME
THE GAME OFFERING IS COMPELLING ENOUGH TO
GIVE AWAY THEIR DNA
PEOPLE WANT TO PERSONALIZE THEIR GAMING
EXPERIENCE

10. WE PUT OUT A SURVEY

11. rockcreek
TAKING IT TO THE STREETS
Michael6076
thogeo Stephen Bess owash

12. THE PIVOT
Do you want to
play a video game
to solve genetic Hey you want to give
problems? up sensitive, personal
information to solve
genetic diseases in the
world?
mrlerone

13. HYPOTHESES 2.0
ALTRUISM IS A BETTER INCENTIVE
PEOPLE WOULD PART WITH THEIR DNA TO BE A PART
OF SOMETHING BIGGER

14. OUR PROPS

15. WE ARE THE SALIVATION ARMY
You spit into a tube
We read your DNA
We combine it into an Army
Together with our industry partners, we crush disease
We report back to you regularly from the front lines

16. SHOWING OUR IDEA TO THE PUBLIC

17. TALKING TO PEOPLE, TAKING SALIVA SAMPLES

18. FACTS

19. THE MVP

20. THE POTENTIAL
$42 BN MARKET
100% ROI PER TRIAL PARTICIPANT

21. THE TEAM
KEVIN MAY, ANDREW EVANS, CHANMI PARK, JENNY WONG