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CRCA.ASN.AU • DECEMBER 2014 • ISSUE 4 K 
CRCA 
SPEC I A L REPORT 
The new class Australian ingenuity making a mark 
on the world stage. Page 18 
ENVIRONMENT 
Fields of glory The $250 billion boom 
in agriculture. Page 14 
SOCIETY 
Vast challenges A targeted approach for wellbeing 
in remote communities. Page 26 
INNOVAT I O N 
Fuel injection Advanced manufacturing driving 
industry forward. Page 23 
B I G P I C T U R E 
Eye on the prize Revolutionising vision correction 
as we age. Page 28 
Where Science Meets Business 
THE 
AUSTRALIA I S S U E 
L E A D E R S I N S C I E N C E 
SMART 
BUSINESS 
How the unsung heroes of Australian R&D 
are driving profits, innovation and 
collaboration at home and overseas 
Kn ow How
GEOLOGICALLY 
STORING CARBON 
LEARNING FROM THE 
OTWAY PROJECT EXPERIENCE 
EDITOR: PETER J COOK 
TEN 
COMMITMENTS 
R EV ISITED 
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!LAN UTLER s 'EOFFREY * #ARY s EVERLEY #LARKE s -ICHAEL $OUGLAS s ARNEY ORAN s ! -ALCOLM 'ILL 
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Visit our website for a wide range of books, journals and magazines 
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FOREWORD 
A meeting of equals 
SCIENCE IS AT the heart 
of Australia’s economy 
and society. It is essential 
to improving our lives – it 
benefits our communities and 
boosts our standard of living. 
Science is in the Industry 
portfolio with good reason. 
By drawing science and 
business closer together we 
can help bring the brilliant, 
world-leading research that 
is taking place in our public 
research institutions out of 
the lab and into the world. 
The government understands 
this. That’s why the Industry 
Innovation and Competitiveness 
Agenda recognises science as 
essential to lifting Australia’s 
rate of business and research 
collaboration in order to deliver 
commercial outcomes, economic 
growth and productivity gains. 
We need to keep our focus on 
creating powerful connections 
between industry and researchers. 
Our $484 million investment in 
“We need to keep our focus on 
creating powerful connections 
between industry and researchers.” 
the Entrepreneurs’ Infrastructure 
Programme includes access to 
advisors who can link businesses 
to appropriate research institutions, 
and matches funding to bring 
research capability into the 
business for specific projects. 
The Federal Government’s 
$476 million investment in the 
Industry Skills Fund, commencing 
January 2015, will create the 
highly-skilled workforce that 
Australia needs to adapt to new 
business growth opportunities. 
By making better use 
of scientific knowledge in 
Australian industry, we can 
generate sustainable economic 
growth and ultimately a higher 
standard of living for the 
nation as a whole. 
Partnering with industry 
is a key growth area 
for science, says 
the Minister for 
Industry, the Hon 
Ian Macfarlane. 
From left 
Dr Andrew Beehag 
General Manager 
CRC for Advanced 
Composite Structures 
(CRC-ACS) – page 23 
Professor Stephen Foster 
Head of School of Civil and 
Environmental Engineering, 
UNSW Australia 
Low Carbon Living CRC 
– page 12 
Professor Murray Norris 
Deputy Director, 
Children’s Cancer 
Institute Australia 
Cancer Therapeutics 
CRC – page 8 
Professor Farzad Safaei 
Director, ICT Research 
Institute, University 
of Wollongong 
Smart Services CRC 
– page 9 
Professor Valerie Linton 
Chief Executive Officer 
Energy Pipelines CRC 
– page 11 
Associate Professor 
Padmaja Sankaridurg 
Program Leader, 
Myopia Control, Brien 
Holden Vision Institute 
Vision CRC – page 28 
Dr Vito Mollica 
Head of Marketing 
and Communications 
Capital Markets CRC 
– page 18 
Jessica Sullivan 
Client Business 
Innovation Leader, 
Graeme Booker 
Operations Leader, 
iSee VC Pty Ltd 
Smart Services CRC 
– page 9 
CSIRO 
C R C A . A S N .OR G K n ow H ow m a g a z i n e 3 
LAUREN TROMPP 
Curtin University 
Curtin University’s partnerships with more than 
90 institutions worldwide mean the university 
has established a strong presence in South-East 
Asia. In addition to our flagship campus in Perth, 
Western Australia, we have campuses in Singapore, 
Sarawak and Sydney, which consolidate our 
international presence. 
www.curtin.edu.au 
At CSIRO, we shape the future. 
We do this by using science to 
solve real issues. Our research 
makes a difference to industry, 
people and the planet. We ask, 
we seek, we solve. We are CSIRO. 
www.csiro.au 
Leaders in science from academia 
and industry involved in Cooperative 
Research Centre (CRC) programs 
gathered at UNSW Australia – 
a partner in more than a dozen 
CRCs – for this special edition of 
KnowHow focusing on science 
in the service of the nation. 
Australia’s Innovators
FEATURES 
TECHNOLOGY 
11 Pipeline design for a safer future 
The Energy Pipelines CRC is working to 
prevent a pipeline disaster ever occurring 
in Australia. 
ENVIRONMENT 
14 Fields of glory 
New technologies at the frontier of Australia’s 
agricultural boom are set to secure our place 
as a strong global competitor. 
SPEC I A L REPORT 
18 The new class 
Australian innovation is making an impact on 
the world stage as businesses and researchers 
forge ahead into foreign markets. 
SPOTLIGHT: ANSTO 
22 Going global 
The Australian Nuclear Science and Technology 
Organisation’s nuclear medicine program 
supplies products for the treatment of one in two 
Australians and many more people worldwide. 
4 K n ow H ow m a g a z i n e 
INNOVATION 
23 Boom time: the new, 
smart manufacturing 
Job stats are low but hopes are high for 
Australia’s beleaguered manufacturing 
sector to transition into a high-tech, 
world-class, niche market operator. 
SOCIETY 
26 The wider view 
The 3% of Australians living in remote regions 
face significant health and social challenges. 
Two CRCs are finding solutions. 
IN THE NEWS 
5 Smart sole support for diabetic feet 
6 Antarctic robots trawl for climate data 
7 Using polymer cell technology for 
cheap renewable energy 
8 Targeting kids’ cancer, gene by gene 
9 iSee: Education’s future 
10 Rabbits’ viral expansion 
GROWTH FACTOR 
12 Fresh opportunities 
The Low Carbon Living CRC’s ambitious 
goal is to drive Australia’s carbon emissions 
down by 10 megatonnes by 2020. 
BIG PICTURE 
28 Eye for detail 
It’s long been accepted that vision declines 
with age, but an Australian invention could 
soon change this. 
THE NEXT BIG THING 
30 The spirit within 
Fairer regulation and better access to 
finance and equity will give entrepreneurs 
plenty of encouragement. 
GIVE SCIENCE 
NOT SOCKS 
Gift a Cosmos subscription 
at cosmosmagazine.com/gift 
INCLUDES FREE DELIVERY 
ANYWHERE IN THE WORLD 
CONTENTS 
14
I N T H E NEWS 
Smart sole support for diabetic feet 
Experts from the Wound 
Management Innovation 
CRC, based at the 
Queensland University of 
Technology (QUT) in 
Brisbane, said a shoe insole 
that communicates with the 
wearer’s phone could prevent 
foot injuries among diabetics. 
Diabetes is one of the fastest 
growing diseases globally, with 
the number of people living with 
diabetes worldwide set to grow 
from 382 million in 2013 to 
592 million by 2035, according 
to Diabetes Australia. Poor blood 
glucose control among diabetics 
can cause nerve damage to 
feet and inhibit blood supply. 
This results in an absence of 
sensation in the feet, which 
can lead to serious foot injury. 
The CRC is about to start 
a patient trial of an insole made 
using pressure-sensing fabric that 
sends a message to a smartphone 
warning of potential damage to 
a diabetic’s feet. 
The pressure-sensitive fabric 
was originally developed at 
RMIT University for elite 
athletes. It has since been 
fine-tuned in consultation 
with experts in podiatry from 
Southern Cross University. 
Electronics in the insole will 
pick up changes in the distribution 
of pressure applied in each step, 
which are indicative of a wearer 
subconsciously favouring a foot 
or part of a foot. The electronics 
will then communicate wirelessly 
to the wearer’s smartphone at the 
point where the patient is at risk 
of foot damage. 
Diabetics are prone to minor 
breaks in the skin of the foot, 
which can lead to ulcers. Patients 
with a history of these ulcers 
have a high risk of the problem 
Research by the Wound Management 
Innovation CRC may lead to a reduction 
of crippling foot injuries for people 
living with diabetes. 
recurring, so the trial will initially 
determine if the technology can 
reduce the recurrence of skin 
breaks. An ulcer on the bottom 
of the foot can develop into an 
injury that penetrates to the 
bone and can cause chronic 
infections, open sores and 
eventually result in amputation. 
CRC Chief Executive 
Officer Dr Ian Griffiths said 
the technology had the potential 
to reduce the incidence of ulcer 
recurrence among people living 
QUT  WMI CRC WMI CRC 
with diabetes, saving them from 
severe pain, possible amputation 
and incapacity. 
“Diabetics have to be very 
careful of foot injuries. An injury 
can cause months of pain and 
anguish. It can keep diabetics off 
their feet and stop them going 
to work, doing the shopping – 
generally leading a normal life.” 
The CRC initiative involves 
QUT, Southern Cross University, 
RMIT and its industrial partner 
Smith  Nephew as an advisor. www.woundcrc.com 
ISTOCK 
The CRC, funded until July 
2018, is working with similar 
organisations in Canada and Wales 
to leverage strengths in scientific 
and clinical research and education 
through an International 
Wound Management Research 
Collaboration. The project 
will focus on a postgraduate 
student exchange program 
and establish the International 
Registry of Wounds. 
C R C A . A S N . AU K n ow H ow m a g a z i n e 5
I N T H E NEWS 
Antarctic robots trawl for climate data 
Surveys by an unmanned 
submarine support 
suggestions that Antarctic 
sea ice is thicker than previously 
thought, according to research 
accepted by Nature Geoscience. 
The data was collected by 
an Autonomous Underwater 
Vehicle (AUV) deployed during 
a two-month exploration in late 
2012 as part of an international 
collaboration between polar 
scientists, including the Antarctic 
Climate and Ecosystems CRC 
(ACE CRC). It’s hoped the work 
will help explain the ‘paradox’ of 
Antarctic sea ice extent, which 
has grown slightly during the 
past 30 years. This is in stark 
contrast to Arctic sea ice, which 
has shown a major decline. 
The research, led by ARC 
Future Fellow Dr Guy Williams, 
provides the most complete 
picture yet of Antarctic sea ice 
thickness and structure. 
6 K n ow H ow m a g a z i n e 
Previously, measurements 
were made via drill holes in 
the ice and supplemented by 
visual observations made from 
icebreakers as they crashed and 
ploughed through the sea ice 
zone, said Williams. 
In contrast, the AUV gathers 
information by travelling beneath 
the ice, producing 3D maps of 
the underside of the ice based 
on data captured by a multi-beam 
sonar instrument. Complex 
imagery of an area the size of 
several football fields can be 
compiled in just six hours. 
The manual drill estimates 
of thickness have never 
exceeded 5–6 m, but the AUV 
regularly returned thicknesses 
over 10 m and up to 16 m. 
“This sort of thick ice 
would simply never be sampled 
by drilling or observations 
from ships,” said Williams. 
“We measured the thickness 
of 10 double football fields, 
and found that our traditional 
method [manual drill lines] 
would have underestimated 
the volume by over 20%.” 
The researchers can’t yet say that 
overall Antarctic sea ice thickness 
is underestimated by this amount. 
They’ll need to use the AUV 
over much longer scales – 
across distances of 1000 km, 
for example – and directly 
compare the results with those 
from traditional methods. 
The AUV is one of two new 
innovative information sources 
being used by ACE CRC 
scientists to explore Antarctic 
sea ice processes and change. 
They’ve also begun tapping into 
environmental data gathered in 
the Southern Ocean by elephant 
seals. These marine mammals 
can dive deeper than 1500 m 
and travel thousands of 
kilometres in a season. 
During the past decade, 
ecologists and biologists have been 
equipping them with specialised 
oceanographic equipment provided 
by Australia’s Integrated Marine 
Observing System, to observe 
where and when they forage. 
“These seals had been going 
to places we could only dream of 
going with a ship,” said Williams. 
The first major breakthrough 
from the seal-gathered data came 
last year with the confirmation of 
a new source of Antarctic bottom 
water, the cold dense water mass 
created by intense sea ice growth 
that ultimately influences 
climate worldwide. 
It’s the fourth source to be 
identified of this influential 
water mass, and scientists had 
been looking for it for more 
than 30 years. – Karen McGhee 
www.acecrc.org.au 
KLAUS MEINERS, AUSTRALIAN ANTARCTIC DIVISION 
Autonomous Underwater Vehicles, as 
well as data-gathering seals (below), 
are revealing surprising global climate 
effects in the Antarctic. 
MARK HINDELL
CRC-P 
Using polymer cell technology 
for cheap renewable energy 
C R C A . A S N . AU 
for Australian manufacturing. 
Officer estimated that, using 
methods developed by the 
CRC-P, polymer cells can be 
produced that cost no more 
than 50 cents per watt – that’s 
less than half the price to 
which the silicon solar cell 
industry aspires. 
Dye-sensitised solar cells first 
created much excitement when 
they were invented 23 years ago, 
but have failed to deliver 
commercially on their early 
promise. So far, only one 
company – Wales-based G24 
Power – is manufacturing the 
cells, and only on a small scale. 
A key obstacle has been the 
cost of materials. “We’ve been 
trying to develop a cost-effective 
solution to producing the solar 
cells using inexpensive materials, 
some of which we’ve made 
ourselves and can scale up 
quite easily,” explained Dagley. 
The CRC has achieved its 
materials and fabrication advances 
through a collaboration of expertise 
across five partner institutions: the 
University of Wollongong – where 
Officer developed new techniques 
that synthesise cheap organic dyes 
– the Australian Nuclear Science 
and Technology Organisation and 
the Universities of Newcastle, 
Queensland and NSW. 
The CRC-P is investigating 
opportunities with sufficiently 
large markets to make 
manufacturing the cells 
cost-effective, which Officer 
said has been another obstacle 
to commercialisation. One 
contender is in horticulture, 
where transparent cells 
incorporated into greenhouses 
could power cooling and water 
pumps. The cells may even be 
able to promote plant growth 
by transmitting only beneficial 
wavelengths of light. 
– Jude Dineley 
We can expect to be 
manufacturing and 
exporting cheap, 
lightweight solar cells (electrical 
devices that convert light energy 
into electricity) to the rest of the 
world by 2019, taking renewable 
energy to remote and off-grid 
communities such as emergency 
refugee camps. 
This prediction came from 
Professor David Officer, head of 
the polymer solar cell program at 
the CRC for Polymers (CRC-P), 
which is developing design and 
manufacturing processes for 
commercially viable polymer solar 
cells based on a light-sensitive dye. 
Officer described the cells as 
a “people’s technology” for the 
future. His optimism is based 
on patents recently secured by 
the CRC-P for components that 
will provide a competitive edge 
over other consortia developing 
similar cells. CEO Dr Ian Dagley 
said CRC-P researchers have 
also pioneered new cost-effective 
manufacturing techniques that, 
for commercial reasons, currently 
remain secret. 
Polymer cells exploit the 
same photovoltaic principle 
as silicon- and glass-based 
rooftop solar panels. Unlike 
those bulky panels, however, 
polymer cells are flexible and 
lightweight and, as a result, can 
be incorporated onto a wide 
range of surfaces – from walls to 
sunshades. Transparent versions 
can even be used in windows. 
They can also operate indoors, 
enabling electricity recycling. 
Crucially, however, polymer 
cells are considerably cheaper 
to manufacture. Silicon cells, 
for example, require expensive 
equipment and carefully 
controlled conditions, while the 
polymer product can be produced 
in minutes with minimal labour 
using reel-to-reel printers, 
presenting new opportunities 
www.crcp.com.au 
K n ow H ow m a g a z i n e 7 
Advances in the design and manufacture of 
polymer solar cells based on light harvesting 
dyes promise a solar power revolution. 
JOSEPH GIORGIO
I N T H E NEWS 
Targeting kids’ cancer, gene by gene 
Cancer researchers in 
Australia are using 
a revolutionary 
‘personalised medicine’ approach 
to identify effective individualised 
treatment options for children. 
The personalised medicine 
platform, which is being developed 
and applied with the support of 
the Cancer Therapeutics CRC, 
will tailor each child’s cancer 
treatment to the particular genetics 
of their individual tumour. 
Then, using a combination of 
in vitro cell growth and testing 
on mice, treatment will be 
determined by the response 
in the laboratory of their own 
cancer cells to drugs. 
The project, led by Professor 
Michelle Haber, Executive Director 
of Australia’s Children’s Cancer 
Institute, in collaboration with 
the National Institutes of Health 
in the USA, has been kickstarted 
with approximately $7.5 million 
in funding from the CRC budget. 
8 K n ow H ow m a g a z i n e 
“Although the survival 
rate of children’s cancer is now 
about 80%, this still means that 
on average about three kids in 
Australia are dying [from the 
disease] every week,” said 
Haber, who won the 2014 
NSW Premier’s Award for 
Outstanding Cancer Research. 
She said it was clear that 
individualised treatment is 
needed. “Two children can 
have the same diagnosis, 
but the standard treatment 
regimen will work for one 
child and fail with the other,” 
she explained. 
The first step in the new 
approach is to take cells from 
a child’s tumour and run them 
through a set of molecular 
profiling tests, which reveal the 
genetic make-up of the cancer. 
Haber’s team will soon settle 
on a panel of about 80 treatable 
genetic abnormalities for their 
targeted molecular profiling tests. 
“We’ve trawled through the 
entire literature, pulling out what 
is known about genes that may 
be suitable for molecular targeted 
drug treatment,” she said. “This 
hasn’t been done for paediatric 
cancer before.” 
The next step is to grow the 
child’s tumour cells. This is done 
either in laboratory flasks or in 
mice with deficient immune 
systems, known as ‘avatar mice’. 
By rapidly scanning the cells, 
the researchers can test many 
drugs, either alone or in 
combinations, to see whether they 
knock back the cancer. And they 
don’t just try cancer drugs. Haber 
said that drugs as disparate as 
beta-blockers used in heart 
disease, as well as malaria drugs, 
can have anti-cancer effects. 
Once a drug is shown to work 
in vitro, the next step is to use it 
in the avatar mice. 
“We have been very excited 
by the excellent responses of the 
first patients to have their 
therapy modified by their 
treating clinicians, on the basis 
of information being generated 
from this new personalised 
medicine platform,” said Haber. 
Clinical trials of the 
platform, to be spearheaded 
by Sydney Children’s Hospital, 
are scheduled for 2017. 
However, Haber hopes it 
will be sooner than that. 
“The CRC funding is 
invaluable,” she said. “It is paying 
for vital staff and their research 
supplies. Of course, this is just 
the beginning for the platform 
and we will only be able to 
handle a few patients at first. 
“Our plan is that, eventually, 
the treatment platform will 
be offered to every child 
in the country who has 
a high-risk malignancy.” 
– Clare Pain 
www.cancercrc.com 
ISTOCK 
Personalised treatment of a child’s 
cancer is based on the genetic 
profiling of the cancer cells. 
JESS HUSBAND PHOTOGRAPHY
iSee: Education’s future 
Australian developers have 
C R C A . A S N . AU 
I N T H E NEWS 
LAUREN TROMPP 
K n ow H ow m a g a z i n e 9 
begun to commercialise 
affordable new software 
that could revolutionise online 
education – as well as our 
interactions on the internet. 
Known as iSee, the technology 
merges videoconferencing with 
interactive, virtual environments. 
It’s been built by University of 
Wollongong (UOW) researchers 
in partnership with the Smart 
Services CRC and now through 
the spin-off company, iSee VC. 
iSee operates by immersing 
dozens of users in a game-like 
setting where they appear 
as ‘mevatars’. 
Like avatars in online 
gaming, ‘mevatars’ represent 
the user in a virtual space. 
However, while avatars are 
typically an alter ego or 
fantasy character, mevatars 
are created by streaming 
the user’s webcam into 
an immersive setting in 
real time, enabling authentic 
face-to-face interactions. 
The technology can stream 
more than 50 webcams in 
a virtual space where users 
can move around, form groups, 
converse and share content. It 
employs point sensitive hearing, 
where multiple users occupying 
the space and engaging in multiple 
conversations will only hear what 
is within earshot – just as they 
would in the real world. 
iSee is designed to mimic 
natural conversations and the 
real life act of mingling, explained 
Chief Technical Officer Professor 
Farzad Safaei, from UOW’s 
ICT Research Institute. 
“You can have multiple, 
simultaneous conversations 
going on in the setting between 
different groups,” Safaei said. 
“Importantly, the user – not the 
system – chooses who to focus on. 
From an education and training 
perspective, this makes it easier 
for students to interact with 
their peers, which is one of the 
key elements missing from 
online education tools.” 
The NSW Department of 
Education and Communities is 
already trialling the iSee program 
to connect secondary students 
and teachers from a large 
metropolitan high school with 
staff and students from a small 
regional high school. 
Colin Wood, who leads the 
department’s Virtual Learning 
Environment team, said the 
technology is helping students 
overcome regional isolation. 
“It eliminates the need to 
travel long distances to experience 
natural social interaction and 
access specialist education, 
training and professional 
development,” he said. Wood 
agreed that a major benefit is 
that users can interact as they 
would in a physical space, 
such as a classroom. 
Teachers have the ability, 
for example, to post slides and 
content on virtual whiteboards, 
break students into groups 
and then circulate, listen to 
the chat and provide feedback. 
Meanwhile, students can 
meet, interact, share ideas and 
collaborate with each other. 
Safaei said iSee requires 
at least 70% less bandwidth 
to operate than other 
videoconferencing systems. 
This is because to any given 
user, it only transmits the audio 
and video from people who are 
visible or within earshot inside 
the virtual setting. 
“You could have 20–25 
users in the environment, but 
one user on average is only 
downloading three to four 
videos,” he said. 
Although commercialisation 
has been initially focused on 
education and training, iSee’s 
Client Business Innovation 
Leader Jessica Sullivan said 
the technology is set to have 
wide-ranging applications 
for organisations interested 
in humanising the web. 
– Myles Gough 
www.isee-meetings.com 
AIMAN ANWAR 
Farzad Safaei, Jessica Sullivan 
and Graeme Booker are all playing 
a role in making iSee software a 
reality for schools and beyond.
I N T H E NEWS 
REBECCA ZANKER 
AUSTRALIA 
OF ARCHIVES NATIONAL The first successful rabbit 
biocontrol in Australia was the 
result of Myxomatosis 
experiments in the 1950s. 
www.invasiveanimals.com Rabbits’ viral expansion “Myxoma and RHDV are the 
The British colonies of the 
South Pacific called an 
inter-colonial commission 
in 1883 to consider matters of 
common interest. German and 
French intentions in the Pacific, 
quarantine and trade issues 
loomed large. So too did the 
rabbit, which less than 25 years 
after its introduction to Australia 
from Europe was considered 
“so serious a national evil” it 
could not be left “to the efforts 
of individuals for its remedy”. 
Within five years, Henry 
Parkes had sponsored an 
international competition 
offering the astounding sum of 
£25,000 to fix the problem. This 
sparked an ongoing quest for 
biological controls for Australia’s 
number one vertebrate pest. 
Where Louis Pasteur and others 
had tried and failed, the CSIRO 
succeeded, twice, with new viral 
1 0 K n ow H ow m a g a z i n e 
controls: myxoma virus in the 
1950s and rabbit haemorrhagic 
disease virus (RHDV, also known 
as rabbit calicivirus) in the 1990s. 
Myxoma received a boost in the 
1960s when a new carrier for the 
virus, the European rabbit flea, 
was introduced. 
The Invasive Animals CRC 
(IA CRC) is hoping to mirror 
that success with a new program 
aimed at improving the impact 
of RHDV. “When we brought 
RHDV to Australia, only one 
strain, a Czech strain, was 
available to us,” said Dr Brian 
Cooke, from the IA CRC and 
the University of Canberra, who 
has spent his career battling 
rabbits using biological controls. 
“We now understand that 
another strain – RCV-A1, which 
doesn’t cause the disease – was 
already here. This immunises 
some rabbits, which is why RHDV 
was less effective in wetter, higher 
production areas where it is 
more prevalent. In arid Australia, 
generally without RCV-A1, 
around 85% of rabbits died.” 
Under the RHD-Boost 
Program, the IA CRC searched 
the world for more effective 
RHDV strains, eventually 
importing and screening 
38 naturally varying strains. 
After additional tests, six were 
further investigated, and two 
virus strains – both from 
South Korea – demonstrated 
advantages over the existing 
Czech strain. One also showed 
an ability to overcome the partial 
protection from the problematic 
RCV-A1 calicivirus. 
CEO of the CRC, Andreas 
Glanznig, said the discovery 
is encouraging but there are 
more steps to take before a new 
RHDV strain can be released. 
only two examples of wide-scale 
viral biocontrol for vertebrate 
animals – ever.” 
The rewards are “potentially 
huge”, he said. “These two 
viruses have so far delivered 
more than $70 billion in value 
to Australia and prevented 
untold environmental damage.” 
Myxoma still kills about half 
the rabbits born in Australia 
today, at zero cost. 
With rabbit numbers on the 
rise, Australia needs to stay on 
the front foot. “It is imperative 
that we have a pipeline of new 
RHDV strains to keep rabbit 
biocontrol effective. The 
alternative will undo decades 
of management of Australia’s 
most costly vertebrate pest,” 
said Glanznig. – Tony Peacock 
NATIONAL ARCHIVES OF AUSTRALIA
T ECHNOLOGY 
Pipeline design 
for a safer future 
The Energy Pipelines CRC is working to prevent a pipeline 
disaster ever occurring in Australia, Clare Pain reports. 
JUST AFTER 6PM on 
9 September 2010, a massive 
explosion rocked the Californian 
suburb of San Bruno. Within seconds, 
a house was engulfed in flames. More 
homes were soon burning ferociously. 
The cause was unknown for almost 
an hour. Some residents thought a plane 
had crashed at nearby San Francisco 
Airport. Others believed there had 
been an earthquake, as San Bruno 
lies close to the San Andreas Fault. 
In fact, a 76 cm gas transmission 
pipeline had ruptured, killing eight 
people and destroying 38 homes. 
Professor Valerie Linton, CEO of the 
Energy Pipelines CRC (EPCRC), has 
a mission to make sure such a pipeline 
disaster never happens in Australia. 
“We’ve got a safety record at least an 
order of magnitude better than any other 
country in terms of our operation of 
energy pipelines. And we want to make 
sure it stays that way,” she says. “There’s 
always a risk that somebody gets overly 
enthusiastic with a digger and makes a hole 
or fracture in a pipeline. In the worst case, 
the fracture ‘unzips’ along the pipe. Our 
researchers have been working to ‘design 
out’ the possibility of fractures occurring, 
and that work has been exceptional.” 
The EPCRC is a collaboration 
between four universities, the Australian 
Government and members of the 
Australian Pipeline Industry Association. 
One particularly significant product of its 
research is the recently released computer 
software called EPDECOM, which 
Linton describes as a leader in its field. 
Pipeline designers can use the software to 
determine the steel properties needed to 
enable the pipeline to withstand damage. 
“North American fracture control 
experts have independently assessed 
EPDECOM, and it performs better than 
any other software available,” says Linton. 
The CRC is also helping to improve 
Australian Standard AS2885 that 
applies to the pipeline industry. This 
relates to the design, construction, 
testing, operations and maintenance 
of gas and petroleum pipelines that 
operate at pressures above 1050 kPa. 
“One of the most direct ways we can 
influence pipeline safety is to make sure 
our research findings get incorporated into 
upgrades of AS2885,” explains Linton. 
An independent testing and research 
laboratory specialising in pipeline coatings 
opened in March 2104 at Deakin 
University – a CRC partner. Testing the 
integrity of pipeline coatings is vital if 
pipes are to be protected from corrosion. 
While much of the EPCRC’s work 
is in engineering, social science also plays 
a central role. Dr Jan Hayes, Program 
Leader for Public Safety and Security of 
Supply, says inquiries into most accidents 
do not reveal new types of equipment 
failure. Usually the technological 
issues are already understood, but 
the knowledge isn’t applied because 
of social issues within organisations. 
One of Hayes’ key goals is to harness 
the learning from pipeline incidents 
around the world. Hayes has co-authored 
a book: Nightmare Pipeline Failures: Fantasy 
Planning, Black Swans And Integrity 
Management. Its intended audience is 
senior executives in energy and chemical 
companies, but it will be publicly available 
and Linton describes it as “very readable”. 
The CRC funded Hayes’ research on the 
San Bruno disaster, which is included 
in the book. It’s another step towards 
keeping Australian energy pipelines safe. 
www.epcrc.com.au 
“We’ve got a safety 
record better 
than any other 
country for our 
operation of 
energy pipelines.” 
NACAP 
ISTOCK 
An Australian gas 
pipeline being 
lowered into 
its trench. 
C R C A . A S N . AU K n ow H ow m a g a z i n e 1 1
GROWTH FACTOR 
Fresh opportunities The Low Carbon Living CRC’s ambitious goal is to drive Australia’s carbon 
emissions down by 10 megatonnes by 2020, Gemma Chilton reports. 
THE WAY WE design, build 
and manage our urban spaces is 
undergoing a transformation that’s 
almost unprecedented in scope. We’re 
reimagining our cities and urban precincts 
in the face of changing climate, energy and 
security issues and a growing appreciation 
for sustainability principles. Individuals 
and organisations from a broad range of 
disciplines will need to play a role. 
Dr Deo Prasad, the CEO of the CRC 
for Low Carbon Living (CRCLCL) and 
a Professor of Sustainable Development at 
the UNSW Faculty of Built Environment, 
personifies this multidisciplinary approach. 
Originally trained as an architect, Prasad 
obtained a master’s degree in science and 
program management and completed 
a PhD in thermal heat transfer in buildings. 
The CRCLCL is a $48 million centre, 
announced in November 2011, of which the 
Commonwealth contribution is $28 million over 
seven years. The centre brings together property 
developers, planners, engineers and policy 
organisations with Australian researchers 
with an overarching aim of reducing carbon 
emissions by 10 megatonnes in the next five 
years – the equivalent of taking 2.3 million cars 
off the road each year. The CRCLCL research 
will bring about $680 million worth of benefits 
to the Australian economy over 15 years. 
“Our focus is on enabling Australian 
industries and particularly small to medium 
enterprises to benefit from the new products, 
technologies, tools and systems. We’re 
trying to ensure the built environment 
sector can capture the benefits from going 
low carbon,” says Prasad. 
1 2 K n ow H ow m a g a z i n e 
Malay Dave, a PhD candidate at the 
CRCLCL and UNSW Australia Built 
Environment, is researching sustainable 
prefabricated or modular housing, with 
an end goal of developing a framework 
for “whole-systems design”. This approach 
considers the house as an energy system 
with interdependent parts, each of which 
affects the performance of the entire system. 
“The need for housing that is both 
sustainable and affordable is a major issue 
globally,” he says. “Prefabrication, or off-site 
construction, offers huge opportunities in 
delivering environmental sustainability and 
economic affordability in buildings.” 
Dave has a $95,000 scholarship funded by 
the CRC, which offers $30,000 per year stipends 
with a total of 88 scholarships available for 
the current funding period of seven years. 
The CRCLCL is also working in parallel 
with the CRC for Polymers (CRC-P) to 
coat building cladding materials such as 
steel or glass with the next generation of 
solar cells – enabling light energy capture 
and distribution throughout a building. 
Researchers at the CRC-P are in the process 
of developing these advanced materials for 
the next generation of solar cells for which 
the CRCLCL is investigating large-scale 
commercial applications (see page 7). 
CEO Dr Ian Dagley says the CRC-P 
has a philosophy of putting postgraduate 
students on the most groundbreaking 
projects. “We want them to be doing 
work of high academic interest using 
state-of-the-art materials and techniques 
so they can publish in high-profile 
international journals,” he says. With 
two-and-a-half years of funding remaining, 
the CRC-P has filled all its 11 postgrad 
scholarships to the value of $1,060,000. 
Other projects at the CRCLCL include 
researching innovative building materials 
such as concrete with reduced embodied 
carbon. They are also developing tools and 
collating data to measure the impact of 
urban developments in terms of water, 
waste, energy and materials. 
The CRCLCL also collaborates with 
the CRC for Water Sensitive Cities for 
this, “developing design ‘charrettes’ [intense 
design workshops] to ensure development 
goals for water and carbon aspirations are 
well-established,” explains Prasad. 
The third main CRCLCL research 
program involves community engagement. 
“Technology or design in itself won’t fix the 
problem,” says Prasad. “We need to look at 
what resonates with communities – why they 
take up certain initiatives and not others.” 
“Our focus is on enabling 
industries to benefit 
from new technologies 
– and that the built 
environment sector can 
capture the benefits 
from going low carbon.” 
ISTOCK 
www.lowcarbonlivingcrc.com.au 
www.crcp.com.au 
www.watersensitivecities.org.au
BRIONY ROGERS 
Research Fellow, Monash University Water for 
Liveability Centre and CRC for Water Sensitive Cities 
Field notes 
WITH BACHELOR DEGREES in civil engineering 
and science and a PhD in environmental sociology, 
Dr Briony Rogers is uniquely placed for her present 
research role. She’s tackling the technical and social challenges 
required to make our urban water systems more sustainable 
and resilient to the impacts of climate change, a growing 
population and increasing urbanisation. 
JANE KELLEY PhD student, 
LaTrobe University AgriBio 
FOR RESEARCHER Jane Kelley, helping an 
individual farmer is just as rewarding as knowing 
that she is helping the entire dairy industry 
overcome one of its biggest threats to milk 
productivity – a parasite called liver fluke. 
“When I finish my lab work, I can email the vet to 
inform them that they need to treat now,” she says. 
“The end product for the farmer will be healthier 
stock, which is important from a welfare perspective 
and also for increased productivity for the farmer.” 
Kelley, who grew up in Gippsland, Victoria, was 
the recipient of the Dairy Australia Award at the 
2014 Science and Innovation Awards for Young 
As a civil engineer, Rogers spent five years working for private 
infrastructure services consultancy GHD where she was responsible 
for civil engineering design and project management on a range of 
water infrastructure projects both in Australia and Vietnam. She was 
passionate about sustainability, but recalls that by the time designs 
landed on her desk, most of the big decisions influencing 
sustainability and resilience had already been made. 
Rogers decided to take on doctoral research at Monash University 
and investigate processes of social change in relation to sustainable 
infrastructure and technology. “I drew on my technical understanding, 
but with the recognition that to implement new approaches, social 
systems would have to change as well,” she says. 
Now, as a Research Fellow for the Monash University Water 
for Liveability Centre and the CRC for Water Sensitive Cities, 
Rogers works with key stakeholders to design strategies and new 
methods to build the “social capital” required to transform the way 
we plan, design and manage our urban water systems. Rogers’ 
interdisciplinary background means she can act as a bridge between 
various stakeholders, from engineers and ecologists to landscape 
architects, as well as organisations such as local councils, state 
government departments and private enterprise. 
The big picture goal, Rogers says, is to transition to “water sensitive 
cities”, in which decentralised, low energy technologies are integrated 
with centralised networks to build resilience in the face of an 
unpredictable future. This requires thinking outside the square, 
she adds, and recognising that water infrastructure “is not just 
a pipe underground”, but a valuable part of the urban landscape, 
providing benefits that can enhance the liveability of a city. She 
gives an example of green cities that are irrigated using harvested 
stormwater to reduce extreme heat during heatwaves. 
“We’ve been building our water systems in large-scale, centralised 
modes for a couple of hundred years, so it is very difficult to change 
our approach,” Rogers says. “That’s partly why this type of research 
is so important – to understand what is locking us into traditional 
systems, so we can overcome those barriers to support innovation 
not just in rhetoric, but in practice.” 
Rogers was this year selected by the International Social Science 
Council to be one of 20 early-career World Social Science Fellows 
in the area of sustainable urbanisation. – Gemma Chilton 
People in Agriculture, Fisheries and Forestry. 
The award came with a grant that has enabled 
her to use a cutting-edge diagnostic technique 
to investigate the prevalence and burden of liver 
fluke on Victorian dairy farms. This is the first 
time the new technique – developed in 2004 by 
a group of Spanish scientists – has been used in 
large-scale field trials in naturally infected cattle. 
The liver fluke parasite currently costs the 
Australian livestock industry $60–90 million every 
year. Kelley hopes her undergraduate research, 
which she is now continuing as a PhD student, will 
help generate improved methods for managing 
the parasite to a point at which the impact on milk 
production and animal welfare is minimal. 
– Gemma Chilton 
HOT-SHOT S 
C R C A . A S N . AU K n ow H ow m a g a z i n e 1 3
ENVIRONMENT 
Fields 
of glory 
New technologies at the frontier of Australia’s 
agricultural boom are set to secure our place as 
a strong global competitor, Rosslyn Beeby reports. 
WITH THE POTENTIAL 
to add $250 billion to 
Australia’s economy over 
the next two decades, according to 
a 2014 report by global consultancy 
Deloitte, agriculture has been deemed 
one of our five “super growth sectors”. 
The Deloitte report, the final in 
its Building the Lucky Country series 
on future prosperity, says agriculture 
could be “as big as mining” for Australia, 
thanks to a combination of factors that 
include an increase in global population, 
rising food demand, food security issues 
and the changing dietary demands of 
Asia’s growing middle class in countries 
like China, India and Indonesia. 
“Essentially, we have what the world 
wants and will increasingly need over 
the next 20 years,” says Rob McConnel, 
Deloitte’s Agribusiness National Leader. 
“The global opportunity becomes 
obvious when you see the numbers, and 
the numbers are compelling. The world’s 
population is around 7 billion and this is 
forecast to increase to 9 billion by 2050, 
which is a 28% increase.” 
The world will need to increase global 
food production by around 75% and 
Australian agribusiness “has the goods” 
to be a major player in meeting this 
demand, he says. But our challenges 
include investing more in research and 
development, improving tertiary education 
courses to produce more agribusiness 
1 4 K n ow H ow m a g a z i n e 
and food science graduates, and “having 
a mature conversation” about foreign 
investment in agribusiness assets. 
Also in 2014, economic consultants 
McKinsey  Company published a report 
on actions needed to build Australia’s 
international competitiveness across 
all sectors of the economy. The report, 
Compete to Prosper – Improving Australia’s 
Global Competitiveness, concludes that 
only one economic sector – agriculture 
– “stands out as strongly competitive”, 
but warns that its future contribution 
to the national economy should not be 
taken for granted. 
While Australia is well-positioned, 
geographically and economically, to 
gain access to new markets in Asia, 
this growth is not assured, the McKinsey 
report says. Australia faces a “pervasive 
competitiveness problem” and many 
sectors of its economy lag behind 
international benchmarks. 
The report argues that disruptive 
technologies such as robotics and 
digital communications are redefining 
economies and global trade, with supply 
chains fragmenting and becoming more 
specialised. The report uses Apple’s iPod 
as an example of a high-demand product 
that contains 451 distinct components 
sourced from around the world. 
This means the global flows of those 
components, or “intermediate goods”, 
are more than three times greater than 
ALAMY 
for the final product, and competition 
is moving from the level of industry 
sectors like manufacturing or retail 
to areas like design and logistics. 
“Tools for file sharing and collaboration 
allow engineering plans to be drafted 
by teams in multiple countries; more 
sophisticated logistics allow construction 
firms to prefabricate everything from 
bathrooms in multi-storey dwellings to 
steel structures for liquefied natural gas 
processing plants,” the McKinsey 
report points out.
This Grasshopper drone 
calculates the best flight 
path to monitor crop health. 
ARCAA 
“Australia has a longstanding worldwide 
reputation for excellence in science related 
to food and agriculture. This is an area where 
Australia can show leadership.” 
WHAT DOES THIS mean for 
Australian agriculture? Future farm 
research teams will include data 
analysts, software programmers, 
agronomists, statisticians, engineers, 
geneticists, cell biologists, hydrologists 
and atmospheric physicists. Farmers 
will use geo-location data to analyse 
climate, water tables and soils, and 
calculate inputs such as fertilisers 
and chemicals for weed and disease 
control. Farm robotics, from drone 
surveillance of livestock and crops 
to sophisticated digital systems 
that track soil moisture and farm 
water management, will be a major 
growth area. 
The Australian Government 
has announced $100 million in new 
grants for rural industries research. 
At the Australasian Research 
Managers Society conference 
in Canberra in September 2014, 
the Department of Agriculture 
Senior Executive Richard Webb 
said “non-traditional areas” such 
as farm robotics will be funded by 
grants offered through Australia’s 
15 Rural Research and Development 
Corporations. Australia is already 
a world leader in this area, Webb 
emphasised, adding that there was 
“plenty of scope” to work across 
industries and to adapt mining and 
defence robotic systems to farming. 
Precision agriculture research, 
which involves the use of satellite 
mapping and remote sensors, is 
another area where Australia can 
lead. The Australian Centre for Field 
Robotics at the University of Sydney 
has developed a world-first robot 
sensor for vegetable farming – 
a solar-powered robot called Ladybird 
that will help farmers collect crop 
data, detect pests and control weeds. 
The Plant Biosecurity CRC is 
working with researchers at the 
Queensland University of Technology 
(QUT) on the use of drones to detect 
diseases in wheat and other crops, as 
well as the spread of the myrtle rust 
fungus in Australia’s national parks. 
Sustainable grazing systems also 
have the potential to improve farm 
productivity and profitability, while 
C R C A . A S N . AU K n ow H ow m a g a z i n e 1 5
making Australia’s farms more resilient 
to climate variability. The Future Farm 
Industries CRC recently ended its 
seven-year research program with 
a string of successes, including two 
Eureka national science awards for its 
use of native perennials and shrubs to 
create drought resistant pasture systems. 
These new pastures can improve nutrition 
for livestock and help control intestinal 
parasites in sheep, reducing drenching 
and chemical costs. Following trials 
by the CRC with farmers in WA and 
NSW, these systems are in use across 
more than 1 million hectares of 
farmland, and estimates suggest 
they could increase farm profitability 
by around $1.6 billion by 2030. 
The Future Farm Industries CRC 
also explored the possibility of planting 
1 6 K n ow H ow m a g a z i n e 
ISTOCK 
www.pbcrc.com.au 
www.sheepcrc.org.au 
www.dairyfuturescrc.com.au 
ENVIRONMENT 
ISTOCK 
“We have what 
the world wants and 
will increasingly 
need over the next 
20 years.” 
The number of 
sheep producers 
who attended 
workshops on 
improving flock 
production of 
pregnant ewes 
in a program 
developed by 
the Sheep CRC. 
1800 
woody crops, such as oil 
mallees, to diversify farm 
income from new industries 
such as aviation biofuels. In 2013, 
it won a CRC Association national 
award for innovation excellence for 
a low-emissions mallee harvester 
(capable of continuous harvesting) 
developed with Richard Sulman, 
Principal Engineer in Australian 
consultancy Biosystems Engineering. 
AUSTRALIA’S GLOBALLY 
competitive agronomists will also make 
greater use of genetics to improve crops 
and livestock. The Sheep CRC is using 
full genomic sequencing to improve the 
effectiveness of DNA tests used by wool 
and sheep meat producers when selecting 
breeding stock. The Dairy Futures CRC 
is involved in a global collaboration of 
more than 20 international participants 
led by Australian scientists to collect 
more than 1000 DNA sequences of 
bulls to identify gene mutations that 
cause embryonic death in dairy cattle 
(see page 20). 
Four years ago, Australia’s Chief 
Scientist Professor Ian Chubb led 
a review of Australia’s 
international agricultural research 
programs and found that when national 
investments in agricultural science, 
technology and training were taken 
into account, the number of people 
benefiting from Australian agricultural 
expertise was around 400 million a year. 
“We are good at this,” he wrote in 
an introduction to the report. “Australia 
has a longstanding worldwide reputation 
for excellence in science related to food 
and agriculture. This is an area where 
Australia can show leadership.” 
GO FIGURE 
Australian agriculture at a glance 
The export value 
of Australian 
agricultural products 
in 2012 – placed in 
the world’s top 15 
in this sector. 
US$38.4 
BILLION 
$131 MILLION 
The government and industry investment in the Plant 
Biosecurity CRC to identify early warning, identification 
and control of plant pests and diseases, safeguard trade and 
market access for grain and horticulture exports and improve 
national awareness of biosecurity issues facing Australia. 
$14 BILLION The value of Australia’s annual crop 
exports from industries that will benefit 
from Plant Biosecurity CRC research. 
The amount earned 
for each dollar 
spent on the Plant 
Biosecurity CRC, 
based on typical 
pest impacts in key 
plant industries. 
$2.56 
ISTOCK
Coming in drones 
DATA ANALYTICS WILL become a thriving 
industry for Australia’s rural towns, providing 
skilled jobs and business opportunities for 
local graduates, says Senior Lecturer 
Dr Felipe Gonzalez from the Queensland 
University of Technology (QUT). 
Working with the Plant Biosecurity CRC, 
Gonzalez is a partner in a $6.5 million 
international research program at QUT 
on the use of unmanned aerial vehicles 
(UAVs) or drones to detect plant pests in 
crops. The project’s research partners also 
include Kansas State University and the 
Victorian Government’s Department of 
Environment and Primary Industries. 
The three-year project is developing 
advanced software for thermal and 
multispectral imaging equipment in UAVs 
to detect the spread of pathogens. These 
include stripe rust in wheat, and myrtle rust, 
which is a threat to native plant crops such 
as tea-tree, eucalypt and callistemon. 
In future farm management, drones 
could be commonly used as ‘farm scouts’ 
to patrol livestock, crops, weeds, feral 
animals and fences. In the process, they 
will collect so much information that a new 
breed of experts will be needed to process, 
collate and interpret the mass of data. 
“We can see a future in which farmers 
would fly their own UAVs or hire a UAV 
contractor,” says Gonzalez. 
“But the farmers won’t want all of the 
data that’s collected. They’ll only want 
what’s relevant to their decision-making, 
so they will rely on data analysts to prepare 
reports. The analysts will design and use 
machine learning programs and other 
artificial intelligence systems to sort, 
select and present information.” 
Gonzalez has given talks to rural 
schools about the UAV project and 
says students are “really excited by 
the technology” and the possibilities 
of using a degree in data analytics to 
contribute to the family farm. 
The UAVs could also be used for 
spraying and seeding crops, collecting 
air samples and surveying large areas 
of land, such as national parks, where 
helicopter surveillance would be difficult 
and costly. At the moment, the challenge 
is to make the use of UAVs a cost-effective 
way for farmers to detect crop diseases 
and pests for agricultural applications. 
Designing and testing a UAV involves 
a complex mix of agriculture knowledge, 
as well as skills in software and 
programming languages to communicate 
instructions to the machine. Future design 
architectures will include fast response, 
real-time algorithms to map and vary 
flight paths, as well as light detection, 
terrain memory and ‘see and avoid’ 
technology to respond to other objects 
in the UAV’s airspace. 
Gonzalez says the technology is 
already delivering good quality images, 
and several farm sectors are keenly 
interested in its future applications. 
“We’re working on issues such as 
determining optimal flying distance 
from plants to get the best images, 
detection rates and data,” he says. 
“This is not a technology that has 
a long way to go,” Gonzalez explains. 
“It’s already being used, and within 
the next two years we should see 
UAVs ready to play a bigger role in 
farm management.” 
C R C A . A S N . AU K n ow H ow m a g a z i n e 1 7 
ISTOCK 
WA DEPT OF AGRICULTURE AND FOOD 
ALAMY 
QUT/ARCAA 
© ARCAA 2014 
Advances in technology will 
transform the way farmers 
monitor, and eventually spray 
and seed, their crops. 
Drones could be used to detect 
the spread of crop pathogens 
such as stripe rust in wheat. 
Right: Visual data 
of a wheat crop taken 
by a ARCAA hexacopter 
UAV at 20 m altitude.
SPEC I A L R E P O RT 
The new class 
Australian innovation is making an impact 
on the world stage as businesses and 
researchers forge ahead into foreign 
markets, says Penny Pryor. 
THERE ARE INCREASING 
signs that Australian RD 
investment in smart sectors 
such as finance and agriculture is reaping 
benefits overseas. Federal Trade and 
Investment Minister Andrew Robb 
points to a 10.4% rise in annual gross 
RD expenditure to $31 billion 
(by 2012). This is twice the 4.9% 
per annum average among countries 
of the Organisation for Economic 
Co-operation and Development (OECD). 
“Australia is a world-class 
innovation destination,” Robb says. 
“This is built on solid foundations of 
modern infrastructure, strong levels 
of investment, generous research and 
development incentives, and strong 
intellectual property protection.” 
In the Global Innovation Index 
2014, Australia achieved its highest 
rank for innovation inputs, coming 
in 10th out of 143 countries and 
placing 22nd for outputs. 
“We have seen a near doubling 
of patents filed abroad by Australian 
entities over a 10-year period,” says 
Ben Mitra-Kahn, Chief Economist at 
IP Australia, the Federal Government’s 
intellectual property office. He believes 
this is an encouraging indication that 
organisations are taking their 
innovations to foreign markets. 
“Our national scientific research 
organisation, CSIRO, ranks in the top 
1% of the world’s scientific institutions 
1 8 K n ow H ow m a g a z i n e 
“We have seen 
a near doubling of 
patents filed abroad 
by Australian 
entities over 
a 10-year period.” 
products and processes – on top 
of the $8.6 billion in direct impacts 
already accrued since the CRC 
Program began in 1991. 
“No one is more interested in or 
committed to maximising research 
impact than CRCs,” says Tony Peacock, 
CEO of the CRC Association. 
[in 15 of 22 research fields],” adds Robb. 
He cites Australia’s development of the 
bionic ear and CSIRO’s pioneering 
wi-fi work as high-profile examples 
of Australian innovation. 
To that list, IP Australia adds ResMed’s 
patented sleep apnoea devices as well 
as Sportwool – a composite superfine 
Merino wool for endurance clothing, 
developed by CSIRO and WoolMark 
and adopted by foreign firms. 
There’s also: the 3D-absorbent 
fabric developed by CSIRO and 
Textor Technologies, which is being 
used in the next generation nappy by 
global brand Huggies; Vision CRC’s 
ongoing work in contact lens technology 
worn by millions worldwide; and the 
Total Channel Control System to 
rejuvenate outdated irrigation systems. 
Total Channel Control is now used 
around the world, and was jointly 
developed by the former CRC 
for Sensor Signal and Information 
Processing, and Rubicon Water. 
Relatively speaking, Australia’s 
weakness is innovation outputs. 
But efforts by many of the CRCs 
are building global relationships that 
will continue to boost the nation’s 
growth. In 2012, a report by Allen 
Consulting Group (now ACIL Allen 
Consulting) predicted that $5.9 billion 
in direct economic impacts would 
accrue during the five years to 2017 
from CRC-produced technologies, 
ADDITIONAL REPORTING BY ROSSLYN BEEBY 
ISTOCK
Australia’s ranking in the 
Global Innovation Index 
21st 
23rd 
19th 
17th 
2011 2012 2013 2014 
The Innovation 
Efficiency Ratio 
97th 
107th 
116th 
81st 
2011 2012 2013 2014 
Taking finance further 
AN EXAMPLE OF successful 
Australian innovation on a global stage 
is the European Capital Markets CRC 
(ECMCRC). Established in early 2013 
by the Australian-based Capital Markets 
CRC (CMCRC) in collaboration with 
European universities, more than seven 
universities were involved at the time 
of writing, with plans for at least 
another seven by early 2015. 
The CMCRC was born out of the 
Securities Industry Research Centre 
of Asia-Pacific (SIRCA), set up in 
the 1990s by current CMCRC 
CEO Professor Michael Aitken 
as a model under which universities 
could collaborate and share knowledge 
and infrastructure and then jointly 
apply for research funding. 
Like its Asia-Pacific predecessor, 
the CMCRC enables the finance and 
business departments of Australian 
universities to build and share 
valuable infrastructure. 
A large amount of time in financial 
market research is spent collecting and 
collating data and the CMCRC has 
developed programs that expedite this 
ISTOCK 
C R C A . A S N . AU K n ow H ow m a g a z i n e 1 9 
SOURCE: WWW.GLOBALINNOVATIONINDEX.ORG 
process. These innovations also enable the 
data to be shared, with the result being 
a drastic reduction in research time. 
One of the CMCRC’s earliest and 
most successful innovations was the 
SMARTS market surveillance system, 
which was sold to the US stock 
exchange NASDAQ in 2010. The 
proceeds of that sale allowed further 
developments, such as the Market 
Quality Dashboard. 
“The Market Quality Dashboard takes 
all that data and produces basic metrics 
that everyone needs to use to analyse 
things like transactions costs and market 
volatility,” Aitken explains. It means 
researchers and academics no longer 
need to develop these metrics from 
scratch, thereby improving productivity. 
In Europe, the ECMCRC will attract 
new members by providing academics 
and universities with access to these tools. 
“What we’re doing is encouraging the 
universities to get together – by giving 
them something they couldn’t hope to 
achieve in a million years – and once 
they’re together, we collectively apply for 
funding from the EU to be matched by 
industry funding, thus sharing the very 
successful CRC model with other 
countries,” Aitken says. 
The university PhD students who use 
the data, and are in industry placements, 
have the joint role of linking the research 
to commercial applications because they 
best understand what companies need. 
Aitken says the CMCRC has already 
built three major pieces of technology 
and created at least 200 new jobs in 
Australian spin-offs as a result. 
“We hope that we will do the 
same in Europe but we need to get 
the universities together first,” he says. 
“By focusing on industry engagement 
first and foremost, we will build 
interesting technology for businesses. 
This will build up ‘brownie points’ 
with industry partners who will 
provide access to their unique data, 
which will in turn foster scholarship.” 
CMCRC’s predecessor, SIRCA, 
has 39 member universities from 
across the region, and Aitken says 
there are already plans in place for 
a capital markets research centre in 
North America in the next five years. 
At its highest ranking to date, Australia is 
placed 17th in the overall Global Innovation 
Index – up six positions since 2012. 
Australia’s innovation output/input ratio ranking 
leapt in one year from 116th to 81st out of 143 
countries in 2014 – a step in the right direction.
A global effort 
THE AREA OF agriculture and 
agribusiness is one of Australia’s five 
key strengths, points out Robb, and 
agricultural CRCs have also been very 
proactive when it comes to international 
cooperation. Two years ago, the 
Dairy Futures CRC launched a global 
research project to create the world’s 
biggest collection of DNA sequence 
data for dairy herd bulls. 
The aim of the 1000 Bulls Genome 
Project was to build a database of 
DNA sequences to be used for 
breeding Australia’s dairy herds. 
From that data, mutations that 
affect animal health, welfare and 
productivity could also be identified. 
A scientific paper analysing the 
genomes of 234 bulls from three dairy 
cattle breeds – Jersey, Holstein-Friesian 
and Fleckvieh – was published in the 
international journal Nature Genetics 
in July 2014. It explains that the research 
team identified 28.3 million genetic 
variants and was able to use the database 
to identify a recessive mutation linked to 
embryonic death in dairy cattle. The 
researchers also identified a dominant 
mutation linked to chondrodysplasia, 
a type of bone disease. 
20 K n ow H ow m a g a z i n e 
“There’s a real opportunity here if 
we can find the genes affecting traits 
that are important to dairy farmers, 
like fertility, milk production and 
disease resistance,” the project’s leader, 
Dr Ben Hayes, recently told the ABC’s 
Country Hour. “We’re combining the 
DNA information with the herd 
records that farmers have kept over 
a large number of years… to sort 
through those 28 million variants 
and come down to a few thousand 
that really do predict milk production, 
fertility and disease resistance.” 
The project involves 20 international 
research partners from Australia, 
France, Germany, Canada, Denmark 
and the USA. Hayes is based at the 
Victorian Department of Environment 
and Primary Industries and leads 
the Dairy Futures CRC’s animal 
improvement research program 
– a partnership between dairy farmers, 
pasture and cattle breeding companies, 
government and researchers. 
Hayes explains that identifying a gene 
mutation that causes embryonic loss in 
cows can help farmers build a healthy, 
more productive dairy herd. “We know 
that this particular mutation is already 
present at low frequency in Australian 
dairy herds. Locating the mutation 
means we can test for it and avoid 
matings between animals that both 
carry the mutation, to keep it from 
becoming a problem in the future.” 
The CRC is also using the project’s 
genetic sequence data to design 
improvements in the routine use of DNA 
to predict the genetic merits of dairy cows. 
“The ultimate challenge in making 
genomic selection more robust is to find 
the variants that are considered to be 
causative – the small fraction of all 
known variants that are responsible 
for major changes to the function of 
important genes,” Hayes says. 
“We now have data for the entire 
DNA sequences, including mutations 
affecting the traits dairy farmers are 
most interested in. We are tracking 
down the causative genes for fertility, 
longevity and meat production, to 
equip farmers to make more informed 
breeding decisions and boost the 
quality of their herds.” 
SPEC I A L R E P O RT 
GO FIGURE 
Australia at a glance 
Australia’s estimated 
nominal GDP – the 
12th largest economy 
in the world and 
4th largest in the 
Asian region. 
$1.7 
TRILLION 
$800 
MILLION 
Dollar value of direct impacts 
accrued by 2012 since the 
CRC Program began in 1991. 
Estimated value of Dairy CRC 
research and innovation to 
Australia’s dairy farmers by 2028. 
that use the CMCRC’s 
award winning SMARTS 
product, developed 
to provide real-time 
surveillance of 
capital markets. 50 
$8.6 BILLION The number of countries
“By focusing on 
industry engagement 
we will build 
technology 
for businesses, 
gain access to 
unique data and 
foster scholarship.” 
THE PORK CRC is another good 
example of global collaboration. 
The CRC has strong links with 
the French National Institute for 
Agricultural Research (INRA) 
on genetic research around disease 
resistance and environmental resilience 
in pigs. Pork CRC Chief Executive 
Officer, Dr Roger Campbell, credits 
the collaboration to the reputation and 
efforts of their geneticist Dr Susanne 
Hermesch, an Associate Professor at 
the Animal Genetics and Breeding Unit, 
based at the University of New England 
in NSW. Hermesch says international 
collaboration is particularly important 
in her field of pig genetics. 
“It’s a small, very specialised 
field, and you really need to look 
for collaboration to get the people 
you want,” she says. Hermesch also 
has collaborative arrangements 
with researchers at organisations 
in New Zealand, Scotland and 
the Netherlands. 
Pork CRC’s attitude towards 
commercialisation of research at 
a national level also means that any 
collaborative international research 
is quickly adopted in the field. 
“Research is part of the adoption 
process,” says Hermesch. “We are 
recording information and data on 
farms in the commercial setting.” 
Australian breeding companies 
collaborate in research, which means 
they must have faith that the research 
outcomes will result in commercial 
benefits for their business. 
“This international collaboration is 
valuable,” adds Hermesch. “I’m pulling 
people from all over the world into my 
extended research team with links to 
the Australian pig industry.” 
Campbell expects there to be global 
advantages from the current genetic 
research because of these ties. 
“The pig industry globally is not 
all that different,” he says. “I would 
expect that all geneticists, and therefore all 
breeding companies, are likely to benefit.” 
www.cmcrc.com 
www.dairyfuturescrc.com.au 
www.visioncrc.org 
www.porkcrc.com.au 
C R C A . A S N . AU K n ow H ow m a g a z i n e 2 1 
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SPEC I A L R E P O RT 
TOKYO. AN ANXIOUS 
42-year-old woman faces 
breast cancer surgery tomorrow. 
She has just had a tiny amount of the 
radioactive element technetium-99m 
injected into her breast ahead of a scan 
that will tell her surgeon which lymph 
nodes to biopsy – thereby increasing the 
effectiveness of her operation. 
She doesn’t know it, but her scan 
relied on ANSTO’s OPAL reactor in 
Sydney, which was designed for nuclear 
medicine and research. Radioactive 
molybdenum-99 (which decays to make 
technetium-99m), arrived at the airport 
just in time to get through customs and 
onto a Qantas flight to Tokyo. 
On landing, it was rushed to a nuclear 
medicine processing company, where it was 
incorporated into a ‘generator’ – a heavily 
shielded device about the size of an esky 
– then couriered to the hospital, where 
the minute dose of technetium needed 
for her scan was drawn off. 
ANSTO has the process of sending 
time-critical nuclear medicine supplies 
across the globe down to a fine art, 
regularly shipping molybdenum-99 
to Asia and the USA. 
“We can get product from Sydney 
to Boston as efficiently as it can be 
shipped there from Europe,” says 
Shaun Jenkinson, ANSTO Nuclear 
Business Group Executive. 
With radioactive elements, time is 
of the essence. Technetium-99m has 
22 K n ow H ow m a g a z i n e 
SPOTLIGHT | ANSTO 
Going global 
The Australian Nuclear Science and Technology Organisation’s 
nuclear medicine program supplies products for the treatment 
of one in two Australians and many more people worldwide, 
Clare Pain reports. 
a half-life of just six hours, which means 
half of it will have decayed into something 
else in that time. This is why it is shipped 
as its precursor, molybdenum-99, which 
has a half-life of 2.75 days. 
ANSTO’s molybdenum-99 exports 
bring in over $10 million each year to 
Australia. This figure is set to triple after 
2016, when its new $100 million nuclear 
medicine processing facility starts up, 
bringing with it 250 new jobs. 
“This will allow us to provide 
about 25% of the global volume of 
molybdenum-99 and, with our joint 
venture South African partners NTP, 
supply about 50% of the world market,” 
Jenkinson says. 
Most of the main reactors producing 
nuclear medicines are fuelled by highly 
enriched uranium (HEU) in the U-235 
isotope, as well as HEU ‘target plates’ 
for making molybdenum-99. HEU is 
also a critical component for nuclear 
weapons. Hence, the use of HEU 
is discouraged in accordance with 
an international treaty on the 
non-proliferation of nuclear weapons. 
The OPAL reactor, however, is 
technologically advanced in that it 
uses low-enriched target plates when 
making molybdenum-99 and runs on 
low-enriched uranium fuel, which 
cannot be diverted to weapons. 
“We lead the way – being good citizens 
of the world by supplying a product that’s 
proliferation-proof,” says Jenkinson. 
In Australia, ANSTO is the major 
supplier of technetium-99m in nuclear 
medicine. “About 600,000 Australians 
have nuclear medicine scans every year,” 
says Professor Paul Roach of the Royal 
North Shore Hospital in Sydney. 
Since only minute amounts are needed 
for each scan – including bone, cardiac, 
lung, thyroid and kidney scans – the 
entire Australian market uses just 60 ml 
of molybdenum-99 per week. But not 
all nations are self-sufficient in this way. 
“There have been real issues in the 
USA when people have struggled to get 
technetium because the old reactors have 
been down for repair,” says Roach. 
As North America’s older reactors 
retire from service over the next two years, 
ANSTO is well-placed to increase its 
output, and take up the challenge of 
providing the necessary medical exports 
to a growing global market. 
ANSTO’s molybdenum-99 exports bring in 
more than $10 million each year to Australia. 
ANSTO’s OPAL reactor enables 
nuclear medical scans, which are 
often used in conjunction with 
computerised tomography (below). 
www.ansto.gov.au 
ANSTO
Boom time: 
the new, smart 
manufacturing 
Job stats are low but hopes are high for Australia’s 
beleaguered manufacturing sector to transition into 
a high-tech, world-class, niche market operator. 
Myles Gough reports. 
C R C A . A S N . AU 
INNOVAT I O N 
K n ow H ow m a g a z i n e 23 
THE EMPLOYMENT 
statistics leave no doubt: traditional 
Australian manufacturing has 
hit rock bottom. The sector has lost 
123,000 jobs in the past decade and 
now accounts for just 7.9% of Australia’s 
total employment – an all-time low. 
Blue Scope Steel closed shop at 
Port Kembla in 2011; in 2014, aluminium 
producer Alcoa shut down its Point Henry 
smelter near Geelong, with more closures 
to follow; and Holden, Ford and Toyota 
have announced plans to cease Australian 
manufacturing operations by 2017. 
The demise of our century-old 
automotive industry will result in the loss 
of several thousand jobs. Many more will 
be threatened in the 160 or so businesses 
involved in the engineering, design and 
manufacture of automotive components. 
“We face a dramatic challenge,” 
says Ian Christensen, CEO of the 
AutoCRC, explaining that ‘made to 
print’ manufacturing – which involves 
no local innovation or design input 
– “now faces a bleak future”. 
But Christensen is convinced there 
will be opportunities for smart operators, 
suggesting two options for component 
manufacturers to remain viable. For one, 
they could apply their expertise to other 
sub-sectors in Australia, such as the 
manufacture of biomedical devices. 
Or, they could find a way to develop 
technologies for offshore automobile 
manufacturers, most likely in Southeast 
Asia, and partner with an overseas 
manufacturer to produce the components. 
“To be successful at all, we must 
focus on value-adding and innovation,” 
Christensen says. “We have to aspire 
to dominate global niches that are 
technically demanding. And we must 
have a deep understanding of customers’ 
needs now and into the future.” 
Minister for Industry Ian Macfarlane 
agrees that manufacturing in Australia 
is transforming rapidly. “If the country 
is to remain globally competitive in 
this area, it must continue shifting 
from a reliance on traditional heavy 
industry to a focus on specialised, 
high-end manufacturing in areas 
of competitive advantage,” he says. 
Part of this shift will be driven 
by research and science, he adds. 
In October 2014, the government 
announced the Industry Innovation 
and Competitiveness Agenda to 
“reset industry policy to put science 
at the centre of industry policy”. 
Advanced manufacturing is one of five 
sectors that the agenda will address. 
CRCs ACROSS AUSTRALIA 
are working hard to carve out these 
niches and developing sophisticated 
new products based on advanced 
manufacturing processes. These 
include lightweight composites 
for the construction industry and 
biotechnologies that will help deliver 
new therapies for a range of illnesses. 
Industry players say they are hopeful 
that expertise in high-tech areas, coupled 
with an aptitude for innovation, will 
help manufacturers overcome traditional 
obstacles such as the high Australian 
dollar, high labour and energy costs 
and geographic disadvantage. 
A large number of companies in 
Australia are adapting and evolving 
to meet the needs of a global economy, 
according to Brad Dunstan, CEO of the 
Victorian Centre for Advanced Materials 
Manufacturing (VCAMM). “The real 
status of Australian manufacturing is 
one of cautious optimism,” he says. 
Here are some examples of where 
a vibrant new Australian manufacturing 
sector might be headed. 
Plant fibre 
bio-composites 
THE DEFENCE, AUTOMOTIVE, 
aerospace and oil and gas industries 
are all showing a strong appetite 
for advanced composite materials here 
and around the world. And Australia’s 
composites industry is well-positioned 
to take advantage of that, according to 
Professor Murray Scott, CEO of 
the CRC for Advanced Composite 
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INNOVAT I O N 
Structures (CRC-ACS). Scott 
says this is because the Australian 
industry is composed predominantly 
of ‘agile’ small-to-medium enterprise 
businesses, able to quickly explore 
new market opportunities. 
“Australia has a fantastic opportunity 
to continue leadership in composites, 
particularly their application in new 
areas,” he says. 
A notable achievement of 
CRC-ACS has been developing 
technology with Boeing Aerostructures 
Australia, which manufactures the 
wing trailing edge devices for the 
Boeing 787 Dreamliner – work 
worth an estimated $4 billion to the 
Australian economy over 25 years. 
One new area of focus is the 
development of bio-composite 
materials that use natural plant fibres 
instead of glass. This allows for an 
environmental impact reduction of 
15–50%, says Dr Andrew Beehag, 
CRC-ACS General Manager. 
Over the short term, CRC-ACS 
has focussed on developing 
lower performance bio-composites 
that can be used as wood and fibreglass 
alternatives in the building and 
construction industry. Researchers 
have already developed a process to 
manufacture composites made from 
2 mm-long plant fibres. This, says 
Beehag, represents a significant 
improvement over the immediate 
market competitor, which has only 
achieved reinforced lengths of around 
0.1 mm and a much weaker performance. 
“Laboratory trials have shown that 
a 30–40% increase in strength may be 
achievable with our approach,” Beehag 
says. And that would come with only 
a 10% higher cost. This gives CRC-ACS 
flexibility to develop a premium product 
with increased performance, or to 
achieve cost savings while maintaining 
current performance standards. 
Two companies are already trialling 
these next generation building products. 
24 K n ow H ow m a g a z i n e 
this grand challenge of high-rate 
composite manufacturing and license 
it to Australian industry, then those 
Australian companies are in the box seat 
to manufacture parts in high volume for 
a burgeoning market,” says Dunstan. 
High performance plastics offer 
another option to reduce vehicle 
weight and improve fuel efficiency in 
the automotive and aviation industries. 
The global market for injection-moulded 
plastics is expected to reach about 
$319 billion by 2020. The creation 
of millions of plastic components for 
transport and other industries begins 
with a single mould. However, 
developing moulds requires highly 
specialised experts in the design stage 
and many prototypes. This generates 
waste and makes the process 
time-consuming and expensive. 
To solve this problem, the AutoCRC, 
along with the Victorian Partnership 
of Advanced Computing and the 
Malaysia Automotive Institute, have 
developed a new software toolkit known 
as vMould. This software application 
intelligently optimises mould design 
and development. It eliminates the need 
for specialists, allows for more accurate 
component designs with fewer flaws – 
meaning fewer prototypes and less waste 
– and improves overall production speed. 
Based on the timing and success of 
these trials, CRC-ACS and its spin-off 
ACS Australia should be in a strong 
position to accelerate commercialisation 
activities, Beehag says. 
Carbon to revitalise 
auto manufacturing 
LIGHTWEIGHT CARBON fibre 
composites are becoming crucial to 
automotive manufacturing around the 
world as companies strive to reduce 
vehicle weight. Reduced weight translates 
into lower fuel consumption costs. 
Australia already has one success 
story with Carbon Revolution 
– a company that has developed 
a one-piece carbon fibre wheel for 
sports cars, which is 40–50% lighter 
than aluminium alternatives. 
But manufacturing carbon fibre 
composites affordably, at the volume 
needed to keep pace with automobile 
production, poses a considerable 
challenge. Dunstan says to be acceptable 
to mainstream manufacturing, the 
composites industry needs to show 
that it can produce one part per minute 
at a cost of about $14 per kilogram. 
Once that challenge is met, he says, 
the floodgates will open. 
To address the problem of affordable 
mass production, the AutoCRC is 
supporting a project investigating 
a novel epoxy resin system. It’s hoped 
that tailored resins will be more adept 
at achieving faster curing times, 
ultimately increasing the rate of 
production as required. 
This work is taking place at Carbon 
Nexus, a $34 million research and pilot 
manufacturing facility in Geelong. It’s 
been developed by Deakin University 
in partnership with VCAMM, with 
support from the Victorian and 
Australian Governments. 
“If we can create new, globally 
relevant intellectual property at 
Carbon Nexus that helps meet 
Australian success 
story Carbon Revolution 
has developed a 
one-piece carbon fibre 
wheel, which is 40–50% 
lighter than aluminium 
alternatives. 
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One of several promising research 
projects already underway at the 
CTM CRC aims to improve islet cell 
transplantation. Transplanted islet cells 
from donor pancreata have significant 
benefits for people with type 1 diabetes 
by potentially enabling them to survive 
without insulin injections. But the 
process of isolating and transplanting 
these cells is fraught with technical 
difficulties, high costs and low accessibility. 
One of the most critical issues is 
the extensive cell death that occurs 
during donor islet processing and after 
transplantation. CRC researchers have 
been working to improve cell survival 
during lab-to-hospital transfers, and 
are engineering ‘scaffolds’ and coatings 
to promote islet cell survival before 
and after transplants. 
Kothari says this will make currently 
prohibitively expensive cell therapies far 
more accessible to a greater number of 
people living with diabetes in Australia 
and elsewhere. 
www.crc-acs.com.au 
www.autocrc.com 
www.ctmcrc.com 
www.amcrc.com.au 
Cell building – 
the biotech path 
ANOTHER INNOVATIVE path for 
Australian manufacturing is biotechnology, 
particularly cell therapies. Cell therapies 
use living cells to replace, repair or 
regenerate damaged or diseased tissue. 
The $59 million CRC for Cell 
Therapy Manufacturing (CTM CRC) 
was set up to develop cost-effective 
manufacturing methods for cell 
therapies and create the pathways 
to put them into clinical practice. 
“The cell therapy industry is 
the fastest growing sector of the 
regenerative medicine market,” 
explains Dr Sherry Kothari, the 
CTM CRC’s Managing Director. 
Despite regulatory and cost hurdles, 
there is already intense international 
competition in the area due to the 
industry’s strong growth potential. 
“Australia has the potential to become 
a world leader in the development of cell 
therapies,” Kothari says. “We have the 
chance to establish ourselves as a leader 
in the field, grow a new manufacturing 
industry, create jobs and, above all, 
transform healthcare outcomes.” 
World-first cell 
manufacturing industry 
WITH GEELONG STILL reeling from 
the decline of traditional manufacturing, 
there’s probably no better place for 
Australia to experience the potential 
of a new style of industry. 
A cell therapy innovation has resulted 
in an exciting new partnership that will 
see an advanced manufacturing plant set 
up in Geelong within the next 18 months 
to manufacture short nano-fibres. These 
are used in high-tech applications, 
including as a medium for cell growth. 
Working with the Advanced 
Manufacturing CRC (AMCRC) in a large 
collaborative project involving Deakin 
University, Monash University and 
VCAMM, Australian biotechnology 
startup Cytomatrix has developed 
world-first technology that enables 
the commercial-scale manufacture of 
haematopoietic stem cells. These are 
used in bone marrow transplants and to 
treat people with leukaemia and other 
cancers, and help restore red and white 
blood cells destroyed by high doses of 
chemo- and radiation-therapy. 
Andrew McLellan, CEO of the AMCRC, 
says the technology could significantly 
shorten hospital stays for transplant 
recipients. It’s a great example, says 
McLellan, of an innovative Australian 
organisation operating in a high value, 
high knowledge-based niche. 
“These organisations need to be 
celebrated and seen as being the leaders 
of what can happen in the future.” 
ST VINCENT’S INSTITUTE, MELBOURNE  
THE ROYAL ADELAIDE HOSPITAL, ADELAIDE 
The CTM CRC aims to improve islet 
cell transplantation, which may help 
people with type 1 diabetes survive 
In a world first, an Australian 
startup has found a way to 
commercially manufacture 
haematopoietic stem cells used 
in bone marrow transplants. 
without insulin injections. 
SPL 
C R C A . A S N . AU K n ow H ow m a g a z i n e 2 5
S O C I E T Y 
The wider view 
The 3% of Australians living in remote 
regions face significant health and 
social challenges. Two CRCs are 
finding solutions, writes Fran Molloy. 
THE PLIGHT OF Aboriginal, 
Torres Strait Islander and other 
people living in remote Australia is 
a “global shame”, warned Dr Tom Calma 
in November 2014. Calma is Chair of 
Ninti One, the not-for-profit organisation 
that manages the CRC for Remote 
Economic Participation (CRC-REP). 
More than half a million Australians 
live in remote areas. Occupying a wide 
range of climate zones across 80% of our 
landmass, these regions encompass diverse 
and rich cultures and unique landscapes. 
This poses big research challenges for 
the CRCs working there – primarily the 
CRC-REP and the Lowitja Institute. 
Headquartered in Alice Springs, 
Ninti One has delivered $239 million in 
social and economic benefits to remote 
Australia since its inception in 2003. 
The research is mostly concerned with 
social good, rather than commercial 
outcomes, which can make the impact 
hard to gauge, says Calma. “Research is 
imperative in order to properly understand 
and improve the lives of people living in 
remote Australia,” he says. 
Calma is a distinguished Aboriginal 
leader and elder of the Kungarakan 
people in the Northern Territory. 
He cites feral camel management as an 
example of economic good delivered by 
26 K n ow H ow m a g a z i n e 
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Aboriginal Community Researcher 
Amunda Gory with Anmatyerre 
artist Margaret Scobie. 
NINTI ONE 
tool, apply it and then report back 
on it. This is integral to getting 
good information.” 
Calma is a critic of what he calls 
“fly-in, fly-out bureaucrats” who spend 
a day or two in a community, speak 
to a few select people and then leave 
thinking they have an understanding 
of the region’s issues. 
“Our research shows that 
non-Indigenous or even Indigenous 
bureaucrats without an understanding 
of a particular community will come 
in with preconceived ideas,” he says, 
adding that this can lead them to frame 
their questions to get a pre-determined 
outcome. Aboriginal people then tell 
bureaucrats what they think they want 
to hear, or the bureaucrats mistake 
silence for agreement, Calma explains. 
Ninti One: 500 rangers were trained to 
control camel populations and map and 
maintain waterholes, preventing more 
than $3 million a year in damage to 
fences, bores and waterholes in pastoral 
properties and local communities. 
Ninti One has invested $1 million in 
their Pastoral Precision Project, which 
uses spatial data to match livestock 
performance to environmental conditions. 
The product is now ready for market 
and is expected to benefit many farmers. 
To assist researchers working on these 
kinds of projects in remote Australia, 
Ninti One has produced guidelines in 
conjunction with community members 
with protocols around confidentiality, for 
example. “Sometimes researchers need to 
understand that they cannot write down 
all the stories,” says Calma. These also 
advise where research information and 
recordings should be kept. 
Ninti One has trained 90 Aboriginal 
Community Researchers who live 
in remote communities to undertake 
research and surveys in the community. 
“They have the capacity to 
understand the language of the 
community, as well as all the nuances 
of behaviours within the community,” 
says Calma. “In working with a client, 
they can come up with a good survey 
“Bureaucrats without 
an understanding 
of a community 
will come in with 
preconceived ideas.”
Since its inception in 2003, 
Alice Springs-based Ninti One has 
delivered $239 million in economic 
and social benefits to rural areas 
throughout Australia. 
THE CRC PROGRAM is the only 
Commonwealth initiative providing 
a link between industry, academia, 
government and the communities 
of remote regions, Calma says. 
“We know from past, bitter 
experience the policies imposed from 
on high and afar seldom work well 
in remote Australia. Only when you 
truly engage the people who live there 
do you get results. 
“At the moment there is evidence 
that the wellbeing of remote Australians 
is at increasing risk, and urgent action is 
needed to reverse this trend and to begin 
building a more optimistic, prosperous 
and equitable future for them.” 
When the CRC analysed employment 
across remote Australia, they found that 
a large percentage of jobs were held by 
non-Indigenous people with a Year 10 
or less level of education, despite 
“more than adequate numbers of 
Aboriginal people with Year 10 and 
above qualifications,” says Rod Reeve, 
Ninti One’s Managing Director. 
Another significant project, led 
by Professor John Guenther from 
Flinders University, aims to identify 
how education can improve outcomes 
for Aboriginal and Torres Strait Islander 
Creating 
solutions 
THE HIGHLY SUCCESSFUL Lowitja Institute, 
established in 2010 as the national institute 
for Aboriginal and Torres Strait Islander health 
research, garnered an additional five years of 
funding in July 2014. The Institute was built on 
14 years of CRCs, beginning with the CRC for 
Aboriginal and Tropical Health in 1997. 
This CRC introduced a new roundtable process, 
which set research priorities involving the community 
as well as researchers and policy-makers – changing 
the way research into Indigenous health took place. 
Pat Anderson, Chair of the Lowitja Institute, 
says the process instituted a new way of 
commissioning projects, with community 
leaders at the centre of decision-making. The 
Institute works collaboratively with stakeholders, 
building up the research skills of Aboriginal 
and Torres Strait Island people along the way. 
“Our guiding principle has always been that, 
in order to improve our health, we need to create 
our own solutions rather than have them imposed 
upon us,” Anderson said at the opening of the 
Institute’s new offices in October 2014. 
Preventative health is high on the agenda. The 
CRC recently evaluated Deadly Choices – a program 
encouraging Aboriginal and Torres Strait Islander 
people in southern Queensland to make healthy 
choices around nutrition, physical activity, smoking 
and use of harmful substances. The seven-week 
school and community-based chronic disease 
prevention and education initiative has grown to 
encompass at least 1000 children from more than 
100 schools and community health programs. 
While substantial progress has been made 
in Indigenous people having a greater stake in 
health service delivery, research and policymaking, 
Anderson points out there’s a long way to go. 
“With life expectancy for Australia’s First 
Peoples still languishing 11 years behind our 
fellow countrymen and women, we clearly 
have our work cut out for us.” 
www.nintione.com.au 
www.crc-rep.com 
www.lowitja.org.au 
C R C A . A S N . AU K n ow H ow m a g a z i n e 2 7 
NINTI ONE 
FIONA HAMILTON PHOTOGRAPHY 
The Hon Shayne Neumann MP, 
Ms Patricia Anderson AO and Ms Kelly 
O’Dwyer MP at the Lowitja Institute. 
people in remote areas. For the 
Anangu people in Central Australia, 
Guenther proposed an academy built 
around a “red dirt” curriculum covering 
rural economics, local histories, digital 
literacies and grammar. 
The principle behind the academy 
comes from other projects Ninti One 
has facilitated, where local and 
non-local knowledge is shared, and 
both knowledge systems are treated 
with equal weight and respect. 
“We try to look at an issue from 
many different directions,” Calma says. 
Calma was formerly Aboriginal 
and Torres Strait Islander Social 
Justice Commissioner at the Human 
Rights Commission, which he points 
out has some aspects in common 
with Ninti One. 
“A human rights-based approach 
and a community development 
approach are very similar. They are 
both about making people the centre 
of what you do, and we recognise 
that all our activities are for the 
constituency of remote Australians.” 
Head Office 
Node (Ninti One office) 
Research Locations 
Remote Australia
FADING VISION 
At age 40–45, if you find you have to hold a book further 
away to read it, you may have developed presbyopia: 
an ageing-related condition in which the eye’s ability to 
focus on near objects is reduced as its lens progressively 
stiffens. At this point in life, some people visit an 
optometrist for the first time. Suddenly they need 
glasses – and will for the rest of their lives. 
If Dr Paul Erickson has his way, however, future 
generations may be heading straight to an ophthalmic 
surgeon to have a revolutionary ‘accommodating gel’ 
injected into their eyes. 
CORNEA 
IRIS 
PUPIL 
LENS 
B I G P I C T U R E 
Eye for 
detail 
It’s long been accepted that vision declines 
with age, but an Australian invention could 
soon change this, writes Clare Pain. 
28 K n ow H ow m a g a z i n e 
FIELD LEADER 
Originally from Pennsylvania, 
USA, Erickson has led the 
accommodating gel project 
since 2010 with significant 
funding from the Vision CRC. 
He is the CEO of Brien Holden 
Vision Pty Ltd and Adventus 
Technology Inc – companies 
through which Vision CRC 
participant the Brien Holden 
Vision Institute develops and 
commercialises its technologies. 
TEAMWORK ADVANCES 
Erickson’s team works with the prestigious Bascom 
Palmer Eye Institute in Florida, USA. The partnership 
has already led to improved medical microscopic 
imaging technology for use during the procedure, 
which could immediately benefit eye surgeons 
conducting cataract operations, Erickson says. 
THE SOLUTION 
The accommodating gel project aims to 
replace the stiff natural lens with a new lens 
made from a siloxane gel – a compound of 
silicone. First, the non-functioning natural 
lens would be extracted through a procedure 
similar to surgery for cataracts (lenses which 
have become opaque). Then, the gel would 
be injected into the transparent lens capsule. 
Finding a suitable material to replace the 
lens has been a 20-year search, says Erickson. 
The requirements are stringent: it must be 
a moderately viscous liquid that can be 
injected, and it must polymerise into a soft, 
flexible gel. It also has to be biocompatible 
and, of course, transparent. Developed in 
Australia, the gel is being trialled in rabbits. 
“We’re fine-tuning the properties,” says 
Erickson. “Over the next two to three years, 
we hope to move into animal models that 
more closely resemble humans, and then 
on to human subjects.” 
DEFINING THE PROBLEM 
The crystalline lenses in our eyes can adjust their focal length (or 
‘accommodate’) by changing shape – bulging or flattening according 
to the tension in fibres that connect the lens to the circular muscle 
surrounding the lens capsule. It’s a very flexible lens, but it evolved 
for a species that lives to around 40 years old, Erickson explains. 
“During a person’s life, the lens material loses its softness and 
flexibility, and at around age 40 the loss begins to accelerate,” 
he adds. “It reaches a point where it’s very difficult for the stiffer 
lens to change its shape in order to see at a normal reading distance.”
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C R C A . A S N . AU K n ow H ow m a g a z i n e 2 9
The spirit within 
An Innovator’s 
Wish List 
Boosting skills 
Removing barriers 
Improving finance 
THE N E X T B I G T H I N G 
Fairer regulation and better access to finance and equity will give 
entrepreneurs plenty of encouragement, says Tony Peacock. 
WE OFTEN HEAR calls 
for a more entrepreneurial 
culture. But what does 
that mean in practical terms? Yes, 
it is affected by our national psyche, 
outlook and attitude to risk. We hear 
that Australians don’t ‘embrace failure’, 
and that our finance sector is too 
conservative in its attitude to science 
and innovation. These opinions might 
be true, but regardless we also have to 
get the building blocks right. 
The ‘next big thing’ might come from 
a series of small steps in developing the 
environment for more innovators and 
entrepreneurs to thrive. The government 
has just released an Industry Innovation 
and Competitiveness Agenda, which 
features a few of the steps that 
will improve the situation for 
entrepreneurs in Australia. 
Issuing share options to employees 
is an important way of attracting talent. 
New companies have an idea, a prayer 
and not much cash. But brilliant young 
people are often willing to take shares or 
options in lieu of salaries for a year or 
two to join the startup entrepreneurial 
adventure. They might take a very low 
salary, or spend a year couch surfing or 
forgoing the benefits of deodorant. 
The incredible stories of the likes 
of Twitter, Instagram, Facebook and 
the rest mean that by taking shares 
in lieu of salary they may strike it rich. 
In Australia, rules introduced in 2009 
killed off this pathway by demanding 
that tax be paid on those shares 
immediately. The government has 
now fixed that issue. 
30 K n ow H ow m a g a z i n e 
Removing barriers is another important 
avenue to increase business competitiveness 
in Australia. Simple things like vaccine 
companies undergoing identical audits 
from different regulatory agencies draws 
cash – and focus – out of the business. 
The government has decided to have 
a serious go at lowering those barriers. 
For the Treasurer’s coming tax review, 
the Minister for Industry has flagged 
two more innovations: crowd sourcing 
of equity finance, and patent boxes. 
Australia is slow on the equity issue, 
with the USA, the UK, Canada and 
New Zealand all ahead of us. But 
the government has received a very 
comprehensive report detailing the 
necessary changes, and action is expected 
soon. The patent box concept, which 
started in the UK, allows companies 
to isolate earnings from patents and 
have them favourably taxed. 
Apart from government, financing of 
innovation is slowly improving. Westpac 
has provided $50 million to Reinventure, 
a venture capital company. CSIRO’s new 
CEO, Larry Marshall, is an Aussie with 
25 years of venture capital experience. 
If the equity-financing model allows 
self-managed super funds to invest, 
then who knows the limits? 
Firing up the entrepreneurial 
spirit in Australia is the next big thing. 
The foundations are quickly being laid 
– next we need the builders to come in. 
The gap year has become common after 
senior secondary school. Wouldn’t it 
be something to see a ‘growth year’, 
when graduates or postgraduates gave 
themselves a year to pursue an idea? 
KnowHow founder 
Tony Peacock is 
the CEO of the CRC 
Association and 2014 
Monash University 
Churchill Fellow at 
The Winston Churchill 
Memorial Trust. 
ISTOCK 
There are brilliant 
young people willing 
to take shares in lieu of 
salaries to join a startup.

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KnowHow Issue 4

  • 1. CRCA.ASN.AU • DECEMBER 2014 • ISSUE 4 K CRCA SPEC I A L REPORT The new class Australian ingenuity making a mark on the world stage. Page 18 ENVIRONMENT Fields of glory The $250 billion boom in agriculture. Page 14 SOCIETY Vast challenges A targeted approach for wellbeing in remote communities. Page 26 INNOVAT I O N Fuel injection Advanced manufacturing driving industry forward. Page 23 B I G P I C T U R E Eye on the prize Revolutionising vision correction as we age. Page 28 Where Science Meets Business THE AUSTRALIA I S S U E L E A D E R S I N S C I E N C E SMART BUSINESS How the unsung heroes of Australian R&D are driving profits, innovation and collaboration at home and overseas Kn ow How
  • 2. GEOLOGICALLY STORING CARBON LEARNING FROM THE OTWAY PROJECT EXPERIENCE EDITOR: PETER J COOK TEN COMMITMENTS R EV ISITED 3ECURING!USTRALIASUTURE%NVIRONMENT %DITORS $AVID,INDENMAYER
  • 3. 3TEPHEN$OVERS AND3TEVE-ORTON *ON!LTMANs$EREKALLs.ICHOLASAXs-AXOURKEs.AOMIROWNs2ALFUCKLEYs!NDREW!URBIDGE !LAN UTLER s 'EOFFREY * #ARY s EVERLEY #LARKE s -ICHAEL $OUGLAS s ARNEY ORAN s ! -ALCOLM 'ILL RENDAN 'LEESON s +EN 'REEN s7ARWICK 'ULLETT s *OHN (ANDMER s 1UENTIN (ANICH s 2ICHARD * (OBBS /VE(OEGH 'ULDBERGs,ESLEY(UGHESs+AREN(USSEYs*OANNE,)SAACs3UE*ACKSONs2ICHARD+INGSFORD .EIL ,AZAROW s $UNCAN ,EADBITTER s )AN ,OWE s !LISTAIR -C)LGORM s IONA -C+ENZIE s .EIL -C+ENZIE 0HIL-C-ANUSs!NTHONY*-C-ICHAELs'AVIN--UDDs3UE/GILVYs(UGH00OSSINGHAMs2ICHARD0RICE 3UZANNE-0ROBERs)AN0ULSFORDs'LENN3ANTsRETT23CHEFFERSs-ICHAEL(3MITHs4IMOTHY3MITH *ONATHAN3OBELSs-ARK3TAFFORD3MITHs7ILL3TEFFENs*OHN7ILLIAMSs3TEPHEN%7ILLIAMSs*OHN7OINARSKI 'RAEME,7ORBOYS Visit our website for a wide range of books, journals and magazines T: 1300 788 000 E: publishing.sales@csiro.au W: www.publish.csiro.au
  • 4. FOREWORD A meeting of equals SCIENCE IS AT the heart of Australia’s economy and society. It is essential to improving our lives – it benefits our communities and boosts our standard of living. Science is in the Industry portfolio with good reason. By drawing science and business closer together we can help bring the brilliant, world-leading research that is taking place in our public research institutions out of the lab and into the world. The government understands this. That’s why the Industry Innovation and Competitiveness Agenda recognises science as essential to lifting Australia’s rate of business and research collaboration in order to deliver commercial outcomes, economic growth and productivity gains. We need to keep our focus on creating powerful connections between industry and researchers. Our $484 million investment in “We need to keep our focus on creating powerful connections between industry and researchers.” the Entrepreneurs’ Infrastructure Programme includes access to advisors who can link businesses to appropriate research institutions, and matches funding to bring research capability into the business for specific projects. The Federal Government’s $476 million investment in the Industry Skills Fund, commencing January 2015, will create the highly-skilled workforce that Australia needs to adapt to new business growth opportunities. By making better use of scientific knowledge in Australian industry, we can generate sustainable economic growth and ultimately a higher standard of living for the nation as a whole. Partnering with industry is a key growth area for science, says the Minister for Industry, the Hon Ian Macfarlane. From left Dr Andrew Beehag General Manager CRC for Advanced Composite Structures (CRC-ACS) – page 23 Professor Stephen Foster Head of School of Civil and Environmental Engineering, UNSW Australia Low Carbon Living CRC – page 12 Professor Murray Norris Deputy Director, Children’s Cancer Institute Australia Cancer Therapeutics CRC – page 8 Professor Farzad Safaei Director, ICT Research Institute, University of Wollongong Smart Services CRC – page 9 Professor Valerie Linton Chief Executive Officer Energy Pipelines CRC – page 11 Associate Professor Padmaja Sankaridurg Program Leader, Myopia Control, Brien Holden Vision Institute Vision CRC – page 28 Dr Vito Mollica Head of Marketing and Communications Capital Markets CRC – page 18 Jessica Sullivan Client Business Innovation Leader, Graeme Booker Operations Leader, iSee VC Pty Ltd Smart Services CRC – page 9 CSIRO C R C A . A S N .OR G K n ow H ow m a g a z i n e 3 LAUREN TROMPP Curtin University Curtin University’s partnerships with more than 90 institutions worldwide mean the university has established a strong presence in South-East Asia. In addition to our flagship campus in Perth, Western Australia, we have campuses in Singapore, Sarawak and Sydney, which consolidate our international presence. www.curtin.edu.au At CSIRO, we shape the future. We do this by using science to solve real issues. Our research makes a difference to industry, people and the planet. We ask, we seek, we solve. We are CSIRO. www.csiro.au Leaders in science from academia and industry involved in Cooperative Research Centre (CRC) programs gathered at UNSW Australia – a partner in more than a dozen CRCs – for this special edition of KnowHow focusing on science in the service of the nation. Australia’s Innovators
  • 5. FEATURES TECHNOLOGY 11 Pipeline design for a safer future The Energy Pipelines CRC is working to prevent a pipeline disaster ever occurring in Australia. ENVIRONMENT 14 Fields of glory New technologies at the frontier of Australia’s agricultural boom are set to secure our place as a strong global competitor. SPEC I A L REPORT 18 The new class Australian innovation is making an impact on the world stage as businesses and researchers forge ahead into foreign markets. SPOTLIGHT: ANSTO 22 Going global The Australian Nuclear Science and Technology Organisation’s nuclear medicine program supplies products for the treatment of one in two Australians and many more people worldwide. 4 K n ow H ow m a g a z i n e INNOVATION 23 Boom time: the new, smart manufacturing Job stats are low but hopes are high for Australia’s beleaguered manufacturing sector to transition into a high-tech, world-class, niche market operator. SOCIETY 26 The wider view The 3% of Australians living in remote regions face significant health and social challenges. Two CRCs are finding solutions. IN THE NEWS 5 Smart sole support for diabetic feet 6 Antarctic robots trawl for climate data 7 Using polymer cell technology for cheap renewable energy 8 Targeting kids’ cancer, gene by gene 9 iSee: Education’s future 10 Rabbits’ viral expansion GROWTH FACTOR 12 Fresh opportunities The Low Carbon Living CRC’s ambitious goal is to drive Australia’s carbon emissions down by 10 megatonnes by 2020. BIG PICTURE 28 Eye for detail It’s long been accepted that vision declines with age, but an Australian invention could soon change this. THE NEXT BIG THING 30 The spirit within Fairer regulation and better access to finance and equity will give entrepreneurs plenty of encouragement. GIVE SCIENCE NOT SOCKS Gift a Cosmos subscription at cosmosmagazine.com/gift INCLUDES FREE DELIVERY ANYWHERE IN THE WORLD CONTENTS 14
  • 6. I N T H E NEWS Smart sole support for diabetic feet Experts from the Wound Management Innovation CRC, based at the Queensland University of Technology (QUT) in Brisbane, said a shoe insole that communicates with the wearer’s phone could prevent foot injuries among diabetics. Diabetes is one of the fastest growing diseases globally, with the number of people living with diabetes worldwide set to grow from 382 million in 2013 to 592 million by 2035, according to Diabetes Australia. Poor blood glucose control among diabetics can cause nerve damage to feet and inhibit blood supply. This results in an absence of sensation in the feet, which can lead to serious foot injury. The CRC is about to start a patient trial of an insole made using pressure-sensing fabric that sends a message to a smartphone warning of potential damage to a diabetic’s feet. The pressure-sensitive fabric was originally developed at RMIT University for elite athletes. It has since been fine-tuned in consultation with experts in podiatry from Southern Cross University. Electronics in the insole will pick up changes in the distribution of pressure applied in each step, which are indicative of a wearer subconsciously favouring a foot or part of a foot. The electronics will then communicate wirelessly to the wearer’s smartphone at the point where the patient is at risk of foot damage. Diabetics are prone to minor breaks in the skin of the foot, which can lead to ulcers. Patients with a history of these ulcers have a high risk of the problem Research by the Wound Management Innovation CRC may lead to a reduction of crippling foot injuries for people living with diabetes. recurring, so the trial will initially determine if the technology can reduce the recurrence of skin breaks. An ulcer on the bottom of the foot can develop into an injury that penetrates to the bone and can cause chronic infections, open sores and eventually result in amputation. CRC Chief Executive Officer Dr Ian Griffiths said the technology had the potential to reduce the incidence of ulcer recurrence among people living QUT WMI CRC WMI CRC with diabetes, saving them from severe pain, possible amputation and incapacity. “Diabetics have to be very careful of foot injuries. An injury can cause months of pain and anguish. It can keep diabetics off their feet and stop them going to work, doing the shopping – generally leading a normal life.” The CRC initiative involves QUT, Southern Cross University, RMIT and its industrial partner Smith Nephew as an advisor. www.woundcrc.com ISTOCK The CRC, funded until July 2018, is working with similar organisations in Canada and Wales to leverage strengths in scientific and clinical research and education through an International Wound Management Research Collaboration. The project will focus on a postgraduate student exchange program and establish the International Registry of Wounds. C R C A . A S N . AU K n ow H ow m a g a z i n e 5
  • 7. I N T H E NEWS Antarctic robots trawl for climate data Surveys by an unmanned submarine support suggestions that Antarctic sea ice is thicker than previously thought, according to research accepted by Nature Geoscience. The data was collected by an Autonomous Underwater Vehicle (AUV) deployed during a two-month exploration in late 2012 as part of an international collaboration between polar scientists, including the Antarctic Climate and Ecosystems CRC (ACE CRC). It’s hoped the work will help explain the ‘paradox’ of Antarctic sea ice extent, which has grown slightly during the past 30 years. This is in stark contrast to Arctic sea ice, which has shown a major decline. The research, led by ARC Future Fellow Dr Guy Williams, provides the most complete picture yet of Antarctic sea ice thickness and structure. 6 K n ow H ow m a g a z i n e Previously, measurements were made via drill holes in the ice and supplemented by visual observations made from icebreakers as they crashed and ploughed through the sea ice zone, said Williams. In contrast, the AUV gathers information by travelling beneath the ice, producing 3D maps of the underside of the ice based on data captured by a multi-beam sonar instrument. Complex imagery of an area the size of several football fields can be compiled in just six hours. The manual drill estimates of thickness have never exceeded 5–6 m, but the AUV regularly returned thicknesses over 10 m and up to 16 m. “This sort of thick ice would simply never be sampled by drilling or observations from ships,” said Williams. “We measured the thickness of 10 double football fields, and found that our traditional method [manual drill lines] would have underestimated the volume by over 20%.” The researchers can’t yet say that overall Antarctic sea ice thickness is underestimated by this amount. They’ll need to use the AUV over much longer scales – across distances of 1000 km, for example – and directly compare the results with those from traditional methods. The AUV is one of two new innovative information sources being used by ACE CRC scientists to explore Antarctic sea ice processes and change. They’ve also begun tapping into environmental data gathered in the Southern Ocean by elephant seals. These marine mammals can dive deeper than 1500 m and travel thousands of kilometres in a season. During the past decade, ecologists and biologists have been equipping them with specialised oceanographic equipment provided by Australia’s Integrated Marine Observing System, to observe where and when they forage. “These seals had been going to places we could only dream of going with a ship,” said Williams. The first major breakthrough from the seal-gathered data came last year with the confirmation of a new source of Antarctic bottom water, the cold dense water mass created by intense sea ice growth that ultimately influences climate worldwide. It’s the fourth source to be identified of this influential water mass, and scientists had been looking for it for more than 30 years. – Karen McGhee www.acecrc.org.au KLAUS MEINERS, AUSTRALIAN ANTARCTIC DIVISION Autonomous Underwater Vehicles, as well as data-gathering seals (below), are revealing surprising global climate effects in the Antarctic. MARK HINDELL
  • 8. CRC-P Using polymer cell technology for cheap renewable energy C R C A . A S N . AU for Australian manufacturing. Officer estimated that, using methods developed by the CRC-P, polymer cells can be produced that cost no more than 50 cents per watt – that’s less than half the price to which the silicon solar cell industry aspires. Dye-sensitised solar cells first created much excitement when they were invented 23 years ago, but have failed to deliver commercially on their early promise. So far, only one company – Wales-based G24 Power – is manufacturing the cells, and only on a small scale. A key obstacle has been the cost of materials. “We’ve been trying to develop a cost-effective solution to producing the solar cells using inexpensive materials, some of which we’ve made ourselves and can scale up quite easily,” explained Dagley. The CRC has achieved its materials and fabrication advances through a collaboration of expertise across five partner institutions: the University of Wollongong – where Officer developed new techniques that synthesise cheap organic dyes – the Australian Nuclear Science and Technology Organisation and the Universities of Newcastle, Queensland and NSW. The CRC-P is investigating opportunities with sufficiently large markets to make manufacturing the cells cost-effective, which Officer said has been another obstacle to commercialisation. One contender is in horticulture, where transparent cells incorporated into greenhouses could power cooling and water pumps. The cells may even be able to promote plant growth by transmitting only beneficial wavelengths of light. – Jude Dineley We can expect to be manufacturing and exporting cheap, lightweight solar cells (electrical devices that convert light energy into electricity) to the rest of the world by 2019, taking renewable energy to remote and off-grid communities such as emergency refugee camps. This prediction came from Professor David Officer, head of the polymer solar cell program at the CRC for Polymers (CRC-P), which is developing design and manufacturing processes for commercially viable polymer solar cells based on a light-sensitive dye. Officer described the cells as a “people’s technology” for the future. His optimism is based on patents recently secured by the CRC-P for components that will provide a competitive edge over other consortia developing similar cells. CEO Dr Ian Dagley said CRC-P researchers have also pioneered new cost-effective manufacturing techniques that, for commercial reasons, currently remain secret. Polymer cells exploit the same photovoltaic principle as silicon- and glass-based rooftop solar panels. Unlike those bulky panels, however, polymer cells are flexible and lightweight and, as a result, can be incorporated onto a wide range of surfaces – from walls to sunshades. Transparent versions can even be used in windows. They can also operate indoors, enabling electricity recycling. Crucially, however, polymer cells are considerably cheaper to manufacture. Silicon cells, for example, require expensive equipment and carefully controlled conditions, while the polymer product can be produced in minutes with minimal labour using reel-to-reel printers, presenting new opportunities www.crcp.com.au K n ow H ow m a g a z i n e 7 Advances in the design and manufacture of polymer solar cells based on light harvesting dyes promise a solar power revolution. JOSEPH GIORGIO
  • 9. I N T H E NEWS Targeting kids’ cancer, gene by gene Cancer researchers in Australia are using a revolutionary ‘personalised medicine’ approach to identify effective individualised treatment options for children. The personalised medicine platform, which is being developed and applied with the support of the Cancer Therapeutics CRC, will tailor each child’s cancer treatment to the particular genetics of their individual tumour. Then, using a combination of in vitro cell growth and testing on mice, treatment will be determined by the response in the laboratory of their own cancer cells to drugs. The project, led by Professor Michelle Haber, Executive Director of Australia’s Children’s Cancer Institute, in collaboration with the National Institutes of Health in the USA, has been kickstarted with approximately $7.5 million in funding from the CRC budget. 8 K n ow H ow m a g a z i n e “Although the survival rate of children’s cancer is now about 80%, this still means that on average about three kids in Australia are dying [from the disease] every week,” said Haber, who won the 2014 NSW Premier’s Award for Outstanding Cancer Research. She said it was clear that individualised treatment is needed. “Two children can have the same diagnosis, but the standard treatment regimen will work for one child and fail with the other,” she explained. The first step in the new approach is to take cells from a child’s tumour and run them through a set of molecular profiling tests, which reveal the genetic make-up of the cancer. Haber’s team will soon settle on a panel of about 80 treatable genetic abnormalities for their targeted molecular profiling tests. “We’ve trawled through the entire literature, pulling out what is known about genes that may be suitable for molecular targeted drug treatment,” she said. “This hasn’t been done for paediatric cancer before.” The next step is to grow the child’s tumour cells. This is done either in laboratory flasks or in mice with deficient immune systems, known as ‘avatar mice’. By rapidly scanning the cells, the researchers can test many drugs, either alone or in combinations, to see whether they knock back the cancer. And they don’t just try cancer drugs. Haber said that drugs as disparate as beta-blockers used in heart disease, as well as malaria drugs, can have anti-cancer effects. Once a drug is shown to work in vitro, the next step is to use it in the avatar mice. “We have been very excited by the excellent responses of the first patients to have their therapy modified by their treating clinicians, on the basis of information being generated from this new personalised medicine platform,” said Haber. Clinical trials of the platform, to be spearheaded by Sydney Children’s Hospital, are scheduled for 2017. However, Haber hopes it will be sooner than that. “The CRC funding is invaluable,” she said. “It is paying for vital staff and their research supplies. Of course, this is just the beginning for the platform and we will only be able to handle a few patients at first. “Our plan is that, eventually, the treatment platform will be offered to every child in the country who has a high-risk malignancy.” – Clare Pain www.cancercrc.com ISTOCK Personalised treatment of a child’s cancer is based on the genetic profiling of the cancer cells. JESS HUSBAND PHOTOGRAPHY
  • 10. iSee: Education’s future Australian developers have C R C A . A S N . AU I N T H E NEWS LAUREN TROMPP K n ow H ow m a g a z i n e 9 begun to commercialise affordable new software that could revolutionise online education – as well as our interactions on the internet. Known as iSee, the technology merges videoconferencing with interactive, virtual environments. It’s been built by University of Wollongong (UOW) researchers in partnership with the Smart Services CRC and now through the spin-off company, iSee VC. iSee operates by immersing dozens of users in a game-like setting where they appear as ‘mevatars’. Like avatars in online gaming, ‘mevatars’ represent the user in a virtual space. However, while avatars are typically an alter ego or fantasy character, mevatars are created by streaming the user’s webcam into an immersive setting in real time, enabling authentic face-to-face interactions. The technology can stream more than 50 webcams in a virtual space where users can move around, form groups, converse and share content. It employs point sensitive hearing, where multiple users occupying the space and engaging in multiple conversations will only hear what is within earshot – just as they would in the real world. iSee is designed to mimic natural conversations and the real life act of mingling, explained Chief Technical Officer Professor Farzad Safaei, from UOW’s ICT Research Institute. “You can have multiple, simultaneous conversations going on in the setting between different groups,” Safaei said. “Importantly, the user – not the system – chooses who to focus on. From an education and training perspective, this makes it easier for students to interact with their peers, which is one of the key elements missing from online education tools.” The NSW Department of Education and Communities is already trialling the iSee program to connect secondary students and teachers from a large metropolitan high school with staff and students from a small regional high school. Colin Wood, who leads the department’s Virtual Learning Environment team, said the technology is helping students overcome regional isolation. “It eliminates the need to travel long distances to experience natural social interaction and access specialist education, training and professional development,” he said. Wood agreed that a major benefit is that users can interact as they would in a physical space, such as a classroom. Teachers have the ability, for example, to post slides and content on virtual whiteboards, break students into groups and then circulate, listen to the chat and provide feedback. Meanwhile, students can meet, interact, share ideas and collaborate with each other. Safaei said iSee requires at least 70% less bandwidth to operate than other videoconferencing systems. This is because to any given user, it only transmits the audio and video from people who are visible or within earshot inside the virtual setting. “You could have 20–25 users in the environment, but one user on average is only downloading three to four videos,” he said. Although commercialisation has been initially focused on education and training, iSee’s Client Business Innovation Leader Jessica Sullivan said the technology is set to have wide-ranging applications for organisations interested in humanising the web. – Myles Gough www.isee-meetings.com AIMAN ANWAR Farzad Safaei, Jessica Sullivan and Graeme Booker are all playing a role in making iSee software a reality for schools and beyond.
  • 11. I N T H E NEWS REBECCA ZANKER AUSTRALIA OF ARCHIVES NATIONAL The first successful rabbit biocontrol in Australia was the result of Myxomatosis experiments in the 1950s. www.invasiveanimals.com Rabbits’ viral expansion “Myxoma and RHDV are the The British colonies of the South Pacific called an inter-colonial commission in 1883 to consider matters of common interest. German and French intentions in the Pacific, quarantine and trade issues loomed large. So too did the rabbit, which less than 25 years after its introduction to Australia from Europe was considered “so serious a national evil” it could not be left “to the efforts of individuals for its remedy”. Within five years, Henry Parkes had sponsored an international competition offering the astounding sum of £25,000 to fix the problem. This sparked an ongoing quest for biological controls for Australia’s number one vertebrate pest. Where Louis Pasteur and others had tried and failed, the CSIRO succeeded, twice, with new viral 1 0 K n ow H ow m a g a z i n e controls: myxoma virus in the 1950s and rabbit haemorrhagic disease virus (RHDV, also known as rabbit calicivirus) in the 1990s. Myxoma received a boost in the 1960s when a new carrier for the virus, the European rabbit flea, was introduced. The Invasive Animals CRC (IA CRC) is hoping to mirror that success with a new program aimed at improving the impact of RHDV. “When we brought RHDV to Australia, only one strain, a Czech strain, was available to us,” said Dr Brian Cooke, from the IA CRC and the University of Canberra, who has spent his career battling rabbits using biological controls. “We now understand that another strain – RCV-A1, which doesn’t cause the disease – was already here. This immunises some rabbits, which is why RHDV was less effective in wetter, higher production areas where it is more prevalent. In arid Australia, generally without RCV-A1, around 85% of rabbits died.” Under the RHD-Boost Program, the IA CRC searched the world for more effective RHDV strains, eventually importing and screening 38 naturally varying strains. After additional tests, six were further investigated, and two virus strains – both from South Korea – demonstrated advantages over the existing Czech strain. One also showed an ability to overcome the partial protection from the problematic RCV-A1 calicivirus. CEO of the CRC, Andreas Glanznig, said the discovery is encouraging but there are more steps to take before a new RHDV strain can be released. only two examples of wide-scale viral biocontrol for vertebrate animals – ever.” The rewards are “potentially huge”, he said. “These two viruses have so far delivered more than $70 billion in value to Australia and prevented untold environmental damage.” Myxoma still kills about half the rabbits born in Australia today, at zero cost. With rabbit numbers on the rise, Australia needs to stay on the front foot. “It is imperative that we have a pipeline of new RHDV strains to keep rabbit biocontrol effective. The alternative will undo decades of management of Australia’s most costly vertebrate pest,” said Glanznig. – Tony Peacock NATIONAL ARCHIVES OF AUSTRALIA
  • 12. T ECHNOLOGY Pipeline design for a safer future The Energy Pipelines CRC is working to prevent a pipeline disaster ever occurring in Australia, Clare Pain reports. JUST AFTER 6PM on 9 September 2010, a massive explosion rocked the Californian suburb of San Bruno. Within seconds, a house was engulfed in flames. More homes were soon burning ferociously. The cause was unknown for almost an hour. Some residents thought a plane had crashed at nearby San Francisco Airport. Others believed there had been an earthquake, as San Bruno lies close to the San Andreas Fault. In fact, a 76 cm gas transmission pipeline had ruptured, killing eight people and destroying 38 homes. Professor Valerie Linton, CEO of the Energy Pipelines CRC (EPCRC), has a mission to make sure such a pipeline disaster never happens in Australia. “We’ve got a safety record at least an order of magnitude better than any other country in terms of our operation of energy pipelines. And we want to make sure it stays that way,” she says. “There’s always a risk that somebody gets overly enthusiastic with a digger and makes a hole or fracture in a pipeline. In the worst case, the fracture ‘unzips’ along the pipe. Our researchers have been working to ‘design out’ the possibility of fractures occurring, and that work has been exceptional.” The EPCRC is a collaboration between four universities, the Australian Government and members of the Australian Pipeline Industry Association. One particularly significant product of its research is the recently released computer software called EPDECOM, which Linton describes as a leader in its field. Pipeline designers can use the software to determine the steel properties needed to enable the pipeline to withstand damage. “North American fracture control experts have independently assessed EPDECOM, and it performs better than any other software available,” says Linton. The CRC is also helping to improve Australian Standard AS2885 that applies to the pipeline industry. This relates to the design, construction, testing, operations and maintenance of gas and petroleum pipelines that operate at pressures above 1050 kPa. “One of the most direct ways we can influence pipeline safety is to make sure our research findings get incorporated into upgrades of AS2885,” explains Linton. An independent testing and research laboratory specialising in pipeline coatings opened in March 2104 at Deakin University – a CRC partner. Testing the integrity of pipeline coatings is vital if pipes are to be protected from corrosion. While much of the EPCRC’s work is in engineering, social science also plays a central role. Dr Jan Hayes, Program Leader for Public Safety and Security of Supply, says inquiries into most accidents do not reveal new types of equipment failure. Usually the technological issues are already understood, but the knowledge isn’t applied because of social issues within organisations. One of Hayes’ key goals is to harness the learning from pipeline incidents around the world. Hayes has co-authored a book: Nightmare Pipeline Failures: Fantasy Planning, Black Swans And Integrity Management. Its intended audience is senior executives in energy and chemical companies, but it will be publicly available and Linton describes it as “very readable”. The CRC funded Hayes’ research on the San Bruno disaster, which is included in the book. It’s another step towards keeping Australian energy pipelines safe. www.epcrc.com.au “We’ve got a safety record better than any other country for our operation of energy pipelines.” NACAP ISTOCK An Australian gas pipeline being lowered into its trench. C R C A . A S N . AU K n ow H ow m a g a z i n e 1 1
  • 13. GROWTH FACTOR Fresh opportunities The Low Carbon Living CRC’s ambitious goal is to drive Australia’s carbon emissions down by 10 megatonnes by 2020, Gemma Chilton reports. THE WAY WE design, build and manage our urban spaces is undergoing a transformation that’s almost unprecedented in scope. We’re reimagining our cities and urban precincts in the face of changing climate, energy and security issues and a growing appreciation for sustainability principles. Individuals and organisations from a broad range of disciplines will need to play a role. Dr Deo Prasad, the CEO of the CRC for Low Carbon Living (CRCLCL) and a Professor of Sustainable Development at the UNSW Faculty of Built Environment, personifies this multidisciplinary approach. Originally trained as an architect, Prasad obtained a master’s degree in science and program management and completed a PhD in thermal heat transfer in buildings. The CRCLCL is a $48 million centre, announced in November 2011, of which the Commonwealth contribution is $28 million over seven years. The centre brings together property developers, planners, engineers and policy organisations with Australian researchers with an overarching aim of reducing carbon emissions by 10 megatonnes in the next five years – the equivalent of taking 2.3 million cars off the road each year. The CRCLCL research will bring about $680 million worth of benefits to the Australian economy over 15 years. “Our focus is on enabling Australian industries and particularly small to medium enterprises to benefit from the new products, technologies, tools and systems. We’re trying to ensure the built environment sector can capture the benefits from going low carbon,” says Prasad. 1 2 K n ow H ow m a g a z i n e Malay Dave, a PhD candidate at the CRCLCL and UNSW Australia Built Environment, is researching sustainable prefabricated or modular housing, with an end goal of developing a framework for “whole-systems design”. This approach considers the house as an energy system with interdependent parts, each of which affects the performance of the entire system. “The need for housing that is both sustainable and affordable is a major issue globally,” he says. “Prefabrication, or off-site construction, offers huge opportunities in delivering environmental sustainability and economic affordability in buildings.” Dave has a $95,000 scholarship funded by the CRC, which offers $30,000 per year stipends with a total of 88 scholarships available for the current funding period of seven years. The CRCLCL is also working in parallel with the CRC for Polymers (CRC-P) to coat building cladding materials such as steel or glass with the next generation of solar cells – enabling light energy capture and distribution throughout a building. Researchers at the CRC-P are in the process of developing these advanced materials for the next generation of solar cells for which the CRCLCL is investigating large-scale commercial applications (see page 7). CEO Dr Ian Dagley says the CRC-P has a philosophy of putting postgraduate students on the most groundbreaking projects. “We want them to be doing work of high academic interest using state-of-the-art materials and techniques so they can publish in high-profile international journals,” he says. With two-and-a-half years of funding remaining, the CRC-P has filled all its 11 postgrad scholarships to the value of $1,060,000. Other projects at the CRCLCL include researching innovative building materials such as concrete with reduced embodied carbon. They are also developing tools and collating data to measure the impact of urban developments in terms of water, waste, energy and materials. The CRCLCL also collaborates with the CRC for Water Sensitive Cities for this, “developing design ‘charrettes’ [intense design workshops] to ensure development goals for water and carbon aspirations are well-established,” explains Prasad. The third main CRCLCL research program involves community engagement. “Technology or design in itself won’t fix the problem,” says Prasad. “We need to look at what resonates with communities – why they take up certain initiatives and not others.” “Our focus is on enabling industries to benefit from new technologies – and that the built environment sector can capture the benefits from going low carbon.” ISTOCK www.lowcarbonlivingcrc.com.au www.crcp.com.au www.watersensitivecities.org.au
  • 14. BRIONY ROGERS Research Fellow, Monash University Water for Liveability Centre and CRC for Water Sensitive Cities Field notes WITH BACHELOR DEGREES in civil engineering and science and a PhD in environmental sociology, Dr Briony Rogers is uniquely placed for her present research role. She’s tackling the technical and social challenges required to make our urban water systems more sustainable and resilient to the impacts of climate change, a growing population and increasing urbanisation. JANE KELLEY PhD student, LaTrobe University AgriBio FOR RESEARCHER Jane Kelley, helping an individual farmer is just as rewarding as knowing that she is helping the entire dairy industry overcome one of its biggest threats to milk productivity – a parasite called liver fluke. “When I finish my lab work, I can email the vet to inform them that they need to treat now,” she says. “The end product for the farmer will be healthier stock, which is important from a welfare perspective and also for increased productivity for the farmer.” Kelley, who grew up in Gippsland, Victoria, was the recipient of the Dairy Australia Award at the 2014 Science and Innovation Awards for Young As a civil engineer, Rogers spent five years working for private infrastructure services consultancy GHD where she was responsible for civil engineering design and project management on a range of water infrastructure projects both in Australia and Vietnam. She was passionate about sustainability, but recalls that by the time designs landed on her desk, most of the big decisions influencing sustainability and resilience had already been made. Rogers decided to take on doctoral research at Monash University and investigate processes of social change in relation to sustainable infrastructure and technology. “I drew on my technical understanding, but with the recognition that to implement new approaches, social systems would have to change as well,” she says. Now, as a Research Fellow for the Monash University Water for Liveability Centre and the CRC for Water Sensitive Cities, Rogers works with key stakeholders to design strategies and new methods to build the “social capital” required to transform the way we plan, design and manage our urban water systems. Rogers’ interdisciplinary background means she can act as a bridge between various stakeholders, from engineers and ecologists to landscape architects, as well as organisations such as local councils, state government departments and private enterprise. The big picture goal, Rogers says, is to transition to “water sensitive cities”, in which decentralised, low energy technologies are integrated with centralised networks to build resilience in the face of an unpredictable future. This requires thinking outside the square, she adds, and recognising that water infrastructure “is not just a pipe underground”, but a valuable part of the urban landscape, providing benefits that can enhance the liveability of a city. She gives an example of green cities that are irrigated using harvested stormwater to reduce extreme heat during heatwaves. “We’ve been building our water systems in large-scale, centralised modes for a couple of hundred years, so it is very difficult to change our approach,” Rogers says. “That’s partly why this type of research is so important – to understand what is locking us into traditional systems, so we can overcome those barriers to support innovation not just in rhetoric, but in practice.” Rogers was this year selected by the International Social Science Council to be one of 20 early-career World Social Science Fellows in the area of sustainable urbanisation. – Gemma Chilton People in Agriculture, Fisheries and Forestry. The award came with a grant that has enabled her to use a cutting-edge diagnostic technique to investigate the prevalence and burden of liver fluke on Victorian dairy farms. This is the first time the new technique – developed in 2004 by a group of Spanish scientists – has been used in large-scale field trials in naturally infected cattle. The liver fluke parasite currently costs the Australian livestock industry $60–90 million every year. Kelley hopes her undergraduate research, which she is now continuing as a PhD student, will help generate improved methods for managing the parasite to a point at which the impact on milk production and animal welfare is minimal. – Gemma Chilton HOT-SHOT S C R C A . A S N . AU K n ow H ow m a g a z i n e 1 3
  • 15. ENVIRONMENT Fields of glory New technologies at the frontier of Australia’s agricultural boom are set to secure our place as a strong global competitor, Rosslyn Beeby reports. WITH THE POTENTIAL to add $250 billion to Australia’s economy over the next two decades, according to a 2014 report by global consultancy Deloitte, agriculture has been deemed one of our five “super growth sectors”. The Deloitte report, the final in its Building the Lucky Country series on future prosperity, says agriculture could be “as big as mining” for Australia, thanks to a combination of factors that include an increase in global population, rising food demand, food security issues and the changing dietary demands of Asia’s growing middle class in countries like China, India and Indonesia. “Essentially, we have what the world wants and will increasingly need over the next 20 years,” says Rob McConnel, Deloitte’s Agribusiness National Leader. “The global opportunity becomes obvious when you see the numbers, and the numbers are compelling. The world’s population is around 7 billion and this is forecast to increase to 9 billion by 2050, which is a 28% increase.” The world will need to increase global food production by around 75% and Australian agribusiness “has the goods” to be a major player in meeting this demand, he says. But our challenges include investing more in research and development, improving tertiary education courses to produce more agribusiness 1 4 K n ow H ow m a g a z i n e and food science graduates, and “having a mature conversation” about foreign investment in agribusiness assets. Also in 2014, economic consultants McKinsey Company published a report on actions needed to build Australia’s international competitiveness across all sectors of the economy. The report, Compete to Prosper – Improving Australia’s Global Competitiveness, concludes that only one economic sector – agriculture – “stands out as strongly competitive”, but warns that its future contribution to the national economy should not be taken for granted. While Australia is well-positioned, geographically and economically, to gain access to new markets in Asia, this growth is not assured, the McKinsey report says. Australia faces a “pervasive competitiveness problem” and many sectors of its economy lag behind international benchmarks. The report argues that disruptive technologies such as robotics and digital communications are redefining economies and global trade, with supply chains fragmenting and becoming more specialised. The report uses Apple’s iPod as an example of a high-demand product that contains 451 distinct components sourced from around the world. This means the global flows of those components, or “intermediate goods”, are more than three times greater than ALAMY for the final product, and competition is moving from the level of industry sectors like manufacturing or retail to areas like design and logistics. “Tools for file sharing and collaboration allow engineering plans to be drafted by teams in multiple countries; more sophisticated logistics allow construction firms to prefabricate everything from bathrooms in multi-storey dwellings to steel structures for liquefied natural gas processing plants,” the McKinsey report points out.
  • 16. This Grasshopper drone calculates the best flight path to monitor crop health. ARCAA “Australia has a longstanding worldwide reputation for excellence in science related to food and agriculture. This is an area where Australia can show leadership.” WHAT DOES THIS mean for Australian agriculture? Future farm research teams will include data analysts, software programmers, agronomists, statisticians, engineers, geneticists, cell biologists, hydrologists and atmospheric physicists. Farmers will use geo-location data to analyse climate, water tables and soils, and calculate inputs such as fertilisers and chemicals for weed and disease control. Farm robotics, from drone surveillance of livestock and crops to sophisticated digital systems that track soil moisture and farm water management, will be a major growth area. The Australian Government has announced $100 million in new grants for rural industries research. At the Australasian Research Managers Society conference in Canberra in September 2014, the Department of Agriculture Senior Executive Richard Webb said “non-traditional areas” such as farm robotics will be funded by grants offered through Australia’s 15 Rural Research and Development Corporations. Australia is already a world leader in this area, Webb emphasised, adding that there was “plenty of scope” to work across industries and to adapt mining and defence robotic systems to farming. Precision agriculture research, which involves the use of satellite mapping and remote sensors, is another area where Australia can lead. The Australian Centre for Field Robotics at the University of Sydney has developed a world-first robot sensor for vegetable farming – a solar-powered robot called Ladybird that will help farmers collect crop data, detect pests and control weeds. The Plant Biosecurity CRC is working with researchers at the Queensland University of Technology (QUT) on the use of drones to detect diseases in wheat and other crops, as well as the spread of the myrtle rust fungus in Australia’s national parks. Sustainable grazing systems also have the potential to improve farm productivity and profitability, while C R C A . A S N . AU K n ow H ow m a g a z i n e 1 5
  • 17. making Australia’s farms more resilient to climate variability. The Future Farm Industries CRC recently ended its seven-year research program with a string of successes, including two Eureka national science awards for its use of native perennials and shrubs to create drought resistant pasture systems. These new pastures can improve nutrition for livestock and help control intestinal parasites in sheep, reducing drenching and chemical costs. Following trials by the CRC with farmers in WA and NSW, these systems are in use across more than 1 million hectares of farmland, and estimates suggest they could increase farm profitability by around $1.6 billion by 2030. The Future Farm Industries CRC also explored the possibility of planting 1 6 K n ow H ow m a g a z i n e ISTOCK www.pbcrc.com.au www.sheepcrc.org.au www.dairyfuturescrc.com.au ENVIRONMENT ISTOCK “We have what the world wants and will increasingly need over the next 20 years.” The number of sheep producers who attended workshops on improving flock production of pregnant ewes in a program developed by the Sheep CRC. 1800 woody crops, such as oil mallees, to diversify farm income from new industries such as aviation biofuels. In 2013, it won a CRC Association national award for innovation excellence for a low-emissions mallee harvester (capable of continuous harvesting) developed with Richard Sulman, Principal Engineer in Australian consultancy Biosystems Engineering. AUSTRALIA’S GLOBALLY competitive agronomists will also make greater use of genetics to improve crops and livestock. The Sheep CRC is using full genomic sequencing to improve the effectiveness of DNA tests used by wool and sheep meat producers when selecting breeding stock. The Dairy Futures CRC is involved in a global collaboration of more than 20 international participants led by Australian scientists to collect more than 1000 DNA sequences of bulls to identify gene mutations that cause embryonic death in dairy cattle (see page 20). Four years ago, Australia’s Chief Scientist Professor Ian Chubb led a review of Australia’s international agricultural research programs and found that when national investments in agricultural science, technology and training were taken into account, the number of people benefiting from Australian agricultural expertise was around 400 million a year. “We are good at this,” he wrote in an introduction to the report. “Australia has a longstanding worldwide reputation for excellence in science related to food and agriculture. This is an area where Australia can show leadership.” GO FIGURE Australian agriculture at a glance The export value of Australian agricultural products in 2012 – placed in the world’s top 15 in this sector. US$38.4 BILLION $131 MILLION The government and industry investment in the Plant Biosecurity CRC to identify early warning, identification and control of plant pests and diseases, safeguard trade and market access for grain and horticulture exports and improve national awareness of biosecurity issues facing Australia. $14 BILLION The value of Australia’s annual crop exports from industries that will benefit from Plant Biosecurity CRC research. The amount earned for each dollar spent on the Plant Biosecurity CRC, based on typical pest impacts in key plant industries. $2.56 ISTOCK
  • 18. Coming in drones DATA ANALYTICS WILL become a thriving industry for Australia’s rural towns, providing skilled jobs and business opportunities for local graduates, says Senior Lecturer Dr Felipe Gonzalez from the Queensland University of Technology (QUT). Working with the Plant Biosecurity CRC, Gonzalez is a partner in a $6.5 million international research program at QUT on the use of unmanned aerial vehicles (UAVs) or drones to detect plant pests in crops. The project’s research partners also include Kansas State University and the Victorian Government’s Department of Environment and Primary Industries. The three-year project is developing advanced software for thermal and multispectral imaging equipment in UAVs to detect the spread of pathogens. These include stripe rust in wheat, and myrtle rust, which is a threat to native plant crops such as tea-tree, eucalypt and callistemon. In future farm management, drones could be commonly used as ‘farm scouts’ to patrol livestock, crops, weeds, feral animals and fences. In the process, they will collect so much information that a new breed of experts will be needed to process, collate and interpret the mass of data. “We can see a future in which farmers would fly their own UAVs or hire a UAV contractor,” says Gonzalez. “But the farmers won’t want all of the data that’s collected. They’ll only want what’s relevant to their decision-making, so they will rely on data analysts to prepare reports. The analysts will design and use machine learning programs and other artificial intelligence systems to sort, select and present information.” Gonzalez has given talks to rural schools about the UAV project and says students are “really excited by the technology” and the possibilities of using a degree in data analytics to contribute to the family farm. The UAVs could also be used for spraying and seeding crops, collecting air samples and surveying large areas of land, such as national parks, where helicopter surveillance would be difficult and costly. At the moment, the challenge is to make the use of UAVs a cost-effective way for farmers to detect crop diseases and pests for agricultural applications. Designing and testing a UAV involves a complex mix of agriculture knowledge, as well as skills in software and programming languages to communicate instructions to the machine. Future design architectures will include fast response, real-time algorithms to map and vary flight paths, as well as light detection, terrain memory and ‘see and avoid’ technology to respond to other objects in the UAV’s airspace. Gonzalez says the technology is already delivering good quality images, and several farm sectors are keenly interested in its future applications. “We’re working on issues such as determining optimal flying distance from plants to get the best images, detection rates and data,” he says. “This is not a technology that has a long way to go,” Gonzalez explains. “It’s already being used, and within the next two years we should see UAVs ready to play a bigger role in farm management.” C R C A . A S N . AU K n ow H ow m a g a z i n e 1 7 ISTOCK WA DEPT OF AGRICULTURE AND FOOD ALAMY QUT/ARCAA © ARCAA 2014 Advances in technology will transform the way farmers monitor, and eventually spray and seed, their crops. Drones could be used to detect the spread of crop pathogens such as stripe rust in wheat. Right: Visual data of a wheat crop taken by a ARCAA hexacopter UAV at 20 m altitude.
  • 19. SPEC I A L R E P O RT The new class Australian innovation is making an impact on the world stage as businesses and researchers forge ahead into foreign markets, says Penny Pryor. THERE ARE INCREASING signs that Australian RD investment in smart sectors such as finance and agriculture is reaping benefits overseas. Federal Trade and Investment Minister Andrew Robb points to a 10.4% rise in annual gross RD expenditure to $31 billion (by 2012). This is twice the 4.9% per annum average among countries of the Organisation for Economic Co-operation and Development (OECD). “Australia is a world-class innovation destination,” Robb says. “This is built on solid foundations of modern infrastructure, strong levels of investment, generous research and development incentives, and strong intellectual property protection.” In the Global Innovation Index 2014, Australia achieved its highest rank for innovation inputs, coming in 10th out of 143 countries and placing 22nd for outputs. “We have seen a near doubling of patents filed abroad by Australian entities over a 10-year period,” says Ben Mitra-Kahn, Chief Economist at IP Australia, the Federal Government’s intellectual property office. He believes this is an encouraging indication that organisations are taking their innovations to foreign markets. “Our national scientific research organisation, CSIRO, ranks in the top 1% of the world’s scientific institutions 1 8 K n ow H ow m a g a z i n e “We have seen a near doubling of patents filed abroad by Australian entities over a 10-year period.” products and processes – on top of the $8.6 billion in direct impacts already accrued since the CRC Program began in 1991. “No one is more interested in or committed to maximising research impact than CRCs,” says Tony Peacock, CEO of the CRC Association. [in 15 of 22 research fields],” adds Robb. He cites Australia’s development of the bionic ear and CSIRO’s pioneering wi-fi work as high-profile examples of Australian innovation. To that list, IP Australia adds ResMed’s patented sleep apnoea devices as well as Sportwool – a composite superfine Merino wool for endurance clothing, developed by CSIRO and WoolMark and adopted by foreign firms. There’s also: the 3D-absorbent fabric developed by CSIRO and Textor Technologies, which is being used in the next generation nappy by global brand Huggies; Vision CRC’s ongoing work in contact lens technology worn by millions worldwide; and the Total Channel Control System to rejuvenate outdated irrigation systems. Total Channel Control is now used around the world, and was jointly developed by the former CRC for Sensor Signal and Information Processing, and Rubicon Water. Relatively speaking, Australia’s weakness is innovation outputs. But efforts by many of the CRCs are building global relationships that will continue to boost the nation’s growth. In 2012, a report by Allen Consulting Group (now ACIL Allen Consulting) predicted that $5.9 billion in direct economic impacts would accrue during the five years to 2017 from CRC-produced technologies, ADDITIONAL REPORTING BY ROSSLYN BEEBY ISTOCK
  • 20. Australia’s ranking in the Global Innovation Index 21st 23rd 19th 17th 2011 2012 2013 2014 The Innovation Efficiency Ratio 97th 107th 116th 81st 2011 2012 2013 2014 Taking finance further AN EXAMPLE OF successful Australian innovation on a global stage is the European Capital Markets CRC (ECMCRC). Established in early 2013 by the Australian-based Capital Markets CRC (CMCRC) in collaboration with European universities, more than seven universities were involved at the time of writing, with plans for at least another seven by early 2015. The CMCRC was born out of the Securities Industry Research Centre of Asia-Pacific (SIRCA), set up in the 1990s by current CMCRC CEO Professor Michael Aitken as a model under which universities could collaborate and share knowledge and infrastructure and then jointly apply for research funding. Like its Asia-Pacific predecessor, the CMCRC enables the finance and business departments of Australian universities to build and share valuable infrastructure. A large amount of time in financial market research is spent collecting and collating data and the CMCRC has developed programs that expedite this ISTOCK C R C A . A S N . AU K n ow H ow m a g a z i n e 1 9 SOURCE: WWW.GLOBALINNOVATIONINDEX.ORG process. These innovations also enable the data to be shared, with the result being a drastic reduction in research time. One of the CMCRC’s earliest and most successful innovations was the SMARTS market surveillance system, which was sold to the US stock exchange NASDAQ in 2010. The proceeds of that sale allowed further developments, such as the Market Quality Dashboard. “The Market Quality Dashboard takes all that data and produces basic metrics that everyone needs to use to analyse things like transactions costs and market volatility,” Aitken explains. It means researchers and academics no longer need to develop these metrics from scratch, thereby improving productivity. In Europe, the ECMCRC will attract new members by providing academics and universities with access to these tools. “What we’re doing is encouraging the universities to get together – by giving them something they couldn’t hope to achieve in a million years – and once they’re together, we collectively apply for funding from the EU to be matched by industry funding, thus sharing the very successful CRC model with other countries,” Aitken says. The university PhD students who use the data, and are in industry placements, have the joint role of linking the research to commercial applications because they best understand what companies need. Aitken says the CMCRC has already built three major pieces of technology and created at least 200 new jobs in Australian spin-offs as a result. “We hope that we will do the same in Europe but we need to get the universities together first,” he says. “By focusing on industry engagement first and foremost, we will build interesting technology for businesses. This will build up ‘brownie points’ with industry partners who will provide access to their unique data, which will in turn foster scholarship.” CMCRC’s predecessor, SIRCA, has 39 member universities from across the region, and Aitken says there are already plans in place for a capital markets research centre in North America in the next five years. At its highest ranking to date, Australia is placed 17th in the overall Global Innovation Index – up six positions since 2012. Australia’s innovation output/input ratio ranking leapt in one year from 116th to 81st out of 143 countries in 2014 – a step in the right direction.
  • 21. A global effort THE AREA OF agriculture and agribusiness is one of Australia’s five key strengths, points out Robb, and agricultural CRCs have also been very proactive when it comes to international cooperation. Two years ago, the Dairy Futures CRC launched a global research project to create the world’s biggest collection of DNA sequence data for dairy herd bulls. The aim of the 1000 Bulls Genome Project was to build a database of DNA sequences to be used for breeding Australia’s dairy herds. From that data, mutations that affect animal health, welfare and productivity could also be identified. A scientific paper analysing the genomes of 234 bulls from three dairy cattle breeds – Jersey, Holstein-Friesian and Fleckvieh – was published in the international journal Nature Genetics in July 2014. It explains that the research team identified 28.3 million genetic variants and was able to use the database to identify a recessive mutation linked to embryonic death in dairy cattle. The researchers also identified a dominant mutation linked to chondrodysplasia, a type of bone disease. 20 K n ow H ow m a g a z i n e “There’s a real opportunity here if we can find the genes affecting traits that are important to dairy farmers, like fertility, milk production and disease resistance,” the project’s leader, Dr Ben Hayes, recently told the ABC’s Country Hour. “We’re combining the DNA information with the herd records that farmers have kept over a large number of years… to sort through those 28 million variants and come down to a few thousand that really do predict milk production, fertility and disease resistance.” The project involves 20 international research partners from Australia, France, Germany, Canada, Denmark and the USA. Hayes is based at the Victorian Department of Environment and Primary Industries and leads the Dairy Futures CRC’s animal improvement research program – a partnership between dairy farmers, pasture and cattle breeding companies, government and researchers. Hayes explains that identifying a gene mutation that causes embryonic loss in cows can help farmers build a healthy, more productive dairy herd. “We know that this particular mutation is already present at low frequency in Australian dairy herds. Locating the mutation means we can test for it and avoid matings between animals that both carry the mutation, to keep it from becoming a problem in the future.” The CRC is also using the project’s genetic sequence data to design improvements in the routine use of DNA to predict the genetic merits of dairy cows. “The ultimate challenge in making genomic selection more robust is to find the variants that are considered to be causative – the small fraction of all known variants that are responsible for major changes to the function of important genes,” Hayes says. “We now have data for the entire DNA sequences, including mutations affecting the traits dairy farmers are most interested in. We are tracking down the causative genes for fertility, longevity and meat production, to equip farmers to make more informed breeding decisions and boost the quality of their herds.” SPEC I A L R E P O RT GO FIGURE Australia at a glance Australia’s estimated nominal GDP – the 12th largest economy in the world and 4th largest in the Asian region. $1.7 TRILLION $800 MILLION Dollar value of direct impacts accrued by 2012 since the CRC Program began in 1991. Estimated value of Dairy CRC research and innovation to Australia’s dairy farmers by 2028. that use the CMCRC’s award winning SMARTS product, developed to provide real-time surveillance of capital markets. 50 $8.6 BILLION The number of countries
  • 22. “By focusing on industry engagement we will build technology for businesses, gain access to unique data and foster scholarship.” THE PORK CRC is another good example of global collaboration. The CRC has strong links with the French National Institute for Agricultural Research (INRA) on genetic research around disease resistance and environmental resilience in pigs. Pork CRC Chief Executive Officer, Dr Roger Campbell, credits the collaboration to the reputation and efforts of their geneticist Dr Susanne Hermesch, an Associate Professor at the Animal Genetics and Breeding Unit, based at the University of New England in NSW. Hermesch says international collaboration is particularly important in her field of pig genetics. “It’s a small, very specialised field, and you really need to look for collaboration to get the people you want,” she says. Hermesch also has collaborative arrangements with researchers at organisations in New Zealand, Scotland and the Netherlands. Pork CRC’s attitude towards commercialisation of research at a national level also means that any collaborative international research is quickly adopted in the field. “Research is part of the adoption process,” says Hermesch. “We are recording information and data on farms in the commercial setting.” Australian breeding companies collaborate in research, which means they must have faith that the research outcomes will result in commercial benefits for their business. “This international collaboration is valuable,” adds Hermesch. “I’m pulling people from all over the world into my extended research team with links to the Australian pig industry.” Campbell expects there to be global advantages from the current genetic research because of these ties. “The pig industry globally is not all that different,” he says. “I would expect that all geneticists, and therefore all breeding companies, are likely to benefit.” www.cmcrc.com www.dairyfuturescrc.com.au www.visioncrc.org www.porkcrc.com.au C R C A . A S N . AU K n ow H ow m a g a z i n e 2 1 ISTOCK ISTOCK ISTOCK
  • 23. SPEC I A L R E P O RT TOKYO. AN ANXIOUS 42-year-old woman faces breast cancer surgery tomorrow. She has just had a tiny amount of the radioactive element technetium-99m injected into her breast ahead of a scan that will tell her surgeon which lymph nodes to biopsy – thereby increasing the effectiveness of her operation. She doesn’t know it, but her scan relied on ANSTO’s OPAL reactor in Sydney, which was designed for nuclear medicine and research. Radioactive molybdenum-99 (which decays to make technetium-99m), arrived at the airport just in time to get through customs and onto a Qantas flight to Tokyo. On landing, it was rushed to a nuclear medicine processing company, where it was incorporated into a ‘generator’ – a heavily shielded device about the size of an esky – then couriered to the hospital, where the minute dose of technetium needed for her scan was drawn off. ANSTO has the process of sending time-critical nuclear medicine supplies across the globe down to a fine art, regularly shipping molybdenum-99 to Asia and the USA. “We can get product from Sydney to Boston as efficiently as it can be shipped there from Europe,” says Shaun Jenkinson, ANSTO Nuclear Business Group Executive. With radioactive elements, time is of the essence. Technetium-99m has 22 K n ow H ow m a g a z i n e SPOTLIGHT | ANSTO Going global The Australian Nuclear Science and Technology Organisation’s nuclear medicine program supplies products for the treatment of one in two Australians and many more people worldwide, Clare Pain reports. a half-life of just six hours, which means half of it will have decayed into something else in that time. This is why it is shipped as its precursor, molybdenum-99, which has a half-life of 2.75 days. ANSTO’s molybdenum-99 exports bring in over $10 million each year to Australia. This figure is set to triple after 2016, when its new $100 million nuclear medicine processing facility starts up, bringing with it 250 new jobs. “This will allow us to provide about 25% of the global volume of molybdenum-99 and, with our joint venture South African partners NTP, supply about 50% of the world market,” Jenkinson says. Most of the main reactors producing nuclear medicines are fuelled by highly enriched uranium (HEU) in the U-235 isotope, as well as HEU ‘target plates’ for making molybdenum-99. HEU is also a critical component for nuclear weapons. Hence, the use of HEU is discouraged in accordance with an international treaty on the non-proliferation of nuclear weapons. The OPAL reactor, however, is technologically advanced in that it uses low-enriched target plates when making molybdenum-99 and runs on low-enriched uranium fuel, which cannot be diverted to weapons. “We lead the way – being good citizens of the world by supplying a product that’s proliferation-proof,” says Jenkinson. In Australia, ANSTO is the major supplier of technetium-99m in nuclear medicine. “About 600,000 Australians have nuclear medicine scans every year,” says Professor Paul Roach of the Royal North Shore Hospital in Sydney. Since only minute amounts are needed for each scan – including bone, cardiac, lung, thyroid and kidney scans – the entire Australian market uses just 60 ml of molybdenum-99 per week. But not all nations are self-sufficient in this way. “There have been real issues in the USA when people have struggled to get technetium because the old reactors have been down for repair,” says Roach. As North America’s older reactors retire from service over the next two years, ANSTO is well-placed to increase its output, and take up the challenge of providing the necessary medical exports to a growing global market. ANSTO’s molybdenum-99 exports bring in more than $10 million each year to Australia. ANSTO’s OPAL reactor enables nuclear medical scans, which are often used in conjunction with computerised tomography (below). www.ansto.gov.au ANSTO
  • 24. Boom time: the new, smart manufacturing Job stats are low but hopes are high for Australia’s beleaguered manufacturing sector to transition into a high-tech, world-class, niche market operator. Myles Gough reports. C R C A . A S N . AU INNOVAT I O N K n ow H ow m a g a z i n e 23 THE EMPLOYMENT statistics leave no doubt: traditional Australian manufacturing has hit rock bottom. The sector has lost 123,000 jobs in the past decade and now accounts for just 7.9% of Australia’s total employment – an all-time low. Blue Scope Steel closed shop at Port Kembla in 2011; in 2014, aluminium producer Alcoa shut down its Point Henry smelter near Geelong, with more closures to follow; and Holden, Ford and Toyota have announced plans to cease Australian manufacturing operations by 2017. The demise of our century-old automotive industry will result in the loss of several thousand jobs. Many more will be threatened in the 160 or so businesses involved in the engineering, design and manufacture of automotive components. “We face a dramatic challenge,” says Ian Christensen, CEO of the AutoCRC, explaining that ‘made to print’ manufacturing – which involves no local innovation or design input – “now faces a bleak future”. But Christensen is convinced there will be opportunities for smart operators, suggesting two options for component manufacturers to remain viable. For one, they could apply their expertise to other sub-sectors in Australia, such as the manufacture of biomedical devices. Or, they could find a way to develop technologies for offshore automobile manufacturers, most likely in Southeast Asia, and partner with an overseas manufacturer to produce the components. “To be successful at all, we must focus on value-adding and innovation,” Christensen says. “We have to aspire to dominate global niches that are technically demanding. And we must have a deep understanding of customers’ needs now and into the future.” Minister for Industry Ian Macfarlane agrees that manufacturing in Australia is transforming rapidly. “If the country is to remain globally competitive in this area, it must continue shifting from a reliance on traditional heavy industry to a focus on specialised, high-end manufacturing in areas of competitive advantage,” he says. Part of this shift will be driven by research and science, he adds. In October 2014, the government announced the Industry Innovation and Competitiveness Agenda to “reset industry policy to put science at the centre of industry policy”. Advanced manufacturing is one of five sectors that the agenda will address. CRCs ACROSS AUSTRALIA are working hard to carve out these niches and developing sophisticated new products based on advanced manufacturing processes. These include lightweight composites for the construction industry and biotechnologies that will help deliver new therapies for a range of illnesses. Industry players say they are hopeful that expertise in high-tech areas, coupled with an aptitude for innovation, will help manufacturers overcome traditional obstacles such as the high Australian dollar, high labour and energy costs and geographic disadvantage. A large number of companies in Australia are adapting and evolving to meet the needs of a global economy, according to Brad Dunstan, CEO of the Victorian Centre for Advanced Materials Manufacturing (VCAMM). “The real status of Australian manufacturing is one of cautious optimism,” he says. Here are some examples of where a vibrant new Australian manufacturing sector might be headed. Plant fibre bio-composites THE DEFENCE, AUTOMOTIVE, aerospace and oil and gas industries are all showing a strong appetite for advanced composite materials here and around the world. And Australia’s composites industry is well-positioned to take advantage of that, according to Professor Murray Scott, CEO of the CRC for Advanced Composite ISTOCK
  • 25. INNOVAT I O N Structures (CRC-ACS). Scott says this is because the Australian industry is composed predominantly of ‘agile’ small-to-medium enterprise businesses, able to quickly explore new market opportunities. “Australia has a fantastic opportunity to continue leadership in composites, particularly their application in new areas,” he says. A notable achievement of CRC-ACS has been developing technology with Boeing Aerostructures Australia, which manufactures the wing trailing edge devices for the Boeing 787 Dreamliner – work worth an estimated $4 billion to the Australian economy over 25 years. One new area of focus is the development of bio-composite materials that use natural plant fibres instead of glass. This allows for an environmental impact reduction of 15–50%, says Dr Andrew Beehag, CRC-ACS General Manager. Over the short term, CRC-ACS has focussed on developing lower performance bio-composites that can be used as wood and fibreglass alternatives in the building and construction industry. Researchers have already developed a process to manufacture composites made from 2 mm-long plant fibres. This, says Beehag, represents a significant improvement over the immediate market competitor, which has only achieved reinforced lengths of around 0.1 mm and a much weaker performance. “Laboratory trials have shown that a 30–40% increase in strength may be achievable with our approach,” Beehag says. And that would come with only a 10% higher cost. This gives CRC-ACS flexibility to develop a premium product with increased performance, or to achieve cost savings while maintaining current performance standards. Two companies are already trialling these next generation building products. 24 K n ow H ow m a g a z i n e this grand challenge of high-rate composite manufacturing and license it to Australian industry, then those Australian companies are in the box seat to manufacture parts in high volume for a burgeoning market,” says Dunstan. High performance plastics offer another option to reduce vehicle weight and improve fuel efficiency in the automotive and aviation industries. The global market for injection-moulded plastics is expected to reach about $319 billion by 2020. The creation of millions of plastic components for transport and other industries begins with a single mould. However, developing moulds requires highly specialised experts in the design stage and many prototypes. This generates waste and makes the process time-consuming and expensive. To solve this problem, the AutoCRC, along with the Victorian Partnership of Advanced Computing and the Malaysia Automotive Institute, have developed a new software toolkit known as vMould. This software application intelligently optimises mould design and development. It eliminates the need for specialists, allows for more accurate component designs with fewer flaws – meaning fewer prototypes and less waste – and improves overall production speed. Based on the timing and success of these trials, CRC-ACS and its spin-off ACS Australia should be in a strong position to accelerate commercialisation activities, Beehag says. Carbon to revitalise auto manufacturing LIGHTWEIGHT CARBON fibre composites are becoming crucial to automotive manufacturing around the world as companies strive to reduce vehicle weight. Reduced weight translates into lower fuel consumption costs. Australia already has one success story with Carbon Revolution – a company that has developed a one-piece carbon fibre wheel for sports cars, which is 40–50% lighter than aluminium alternatives. But manufacturing carbon fibre composites affordably, at the volume needed to keep pace with automobile production, poses a considerable challenge. Dunstan says to be acceptable to mainstream manufacturing, the composites industry needs to show that it can produce one part per minute at a cost of about $14 per kilogram. Once that challenge is met, he says, the floodgates will open. To address the problem of affordable mass production, the AutoCRC is supporting a project investigating a novel epoxy resin system. It’s hoped that tailored resins will be more adept at achieving faster curing times, ultimately increasing the rate of production as required. This work is taking place at Carbon Nexus, a $34 million research and pilot manufacturing facility in Geelong. It’s been developed by Deakin University in partnership with VCAMM, with support from the Victorian and Australian Governments. “If we can create new, globally relevant intellectual property at Carbon Nexus that helps meet Australian success story Carbon Revolution has developed a one-piece carbon fibre wheel, which is 40–50% lighter than aluminium alternatives. ISTOCK ISTOCK
  • 26. One of several promising research projects already underway at the CTM CRC aims to improve islet cell transplantation. Transplanted islet cells from donor pancreata have significant benefits for people with type 1 diabetes by potentially enabling them to survive without insulin injections. But the process of isolating and transplanting these cells is fraught with technical difficulties, high costs and low accessibility. One of the most critical issues is the extensive cell death that occurs during donor islet processing and after transplantation. CRC researchers have been working to improve cell survival during lab-to-hospital transfers, and are engineering ‘scaffolds’ and coatings to promote islet cell survival before and after transplants. Kothari says this will make currently prohibitively expensive cell therapies far more accessible to a greater number of people living with diabetes in Australia and elsewhere. www.crc-acs.com.au www.autocrc.com www.ctmcrc.com www.amcrc.com.au Cell building – the biotech path ANOTHER INNOVATIVE path for Australian manufacturing is biotechnology, particularly cell therapies. Cell therapies use living cells to replace, repair or regenerate damaged or diseased tissue. The $59 million CRC for Cell Therapy Manufacturing (CTM CRC) was set up to develop cost-effective manufacturing methods for cell therapies and create the pathways to put them into clinical practice. “The cell therapy industry is the fastest growing sector of the regenerative medicine market,” explains Dr Sherry Kothari, the CTM CRC’s Managing Director. Despite regulatory and cost hurdles, there is already intense international competition in the area due to the industry’s strong growth potential. “Australia has the potential to become a world leader in the development of cell therapies,” Kothari says. “We have the chance to establish ourselves as a leader in the field, grow a new manufacturing industry, create jobs and, above all, transform healthcare outcomes.” World-first cell manufacturing industry WITH GEELONG STILL reeling from the decline of traditional manufacturing, there’s probably no better place for Australia to experience the potential of a new style of industry. A cell therapy innovation has resulted in an exciting new partnership that will see an advanced manufacturing plant set up in Geelong within the next 18 months to manufacture short nano-fibres. These are used in high-tech applications, including as a medium for cell growth. Working with the Advanced Manufacturing CRC (AMCRC) in a large collaborative project involving Deakin University, Monash University and VCAMM, Australian biotechnology startup Cytomatrix has developed world-first technology that enables the commercial-scale manufacture of haematopoietic stem cells. These are used in bone marrow transplants and to treat people with leukaemia and other cancers, and help restore red and white blood cells destroyed by high doses of chemo- and radiation-therapy. Andrew McLellan, CEO of the AMCRC, says the technology could significantly shorten hospital stays for transplant recipients. It’s a great example, says McLellan, of an innovative Australian organisation operating in a high value, high knowledge-based niche. “These organisations need to be celebrated and seen as being the leaders of what can happen in the future.” ST VINCENT’S INSTITUTE, MELBOURNE THE ROYAL ADELAIDE HOSPITAL, ADELAIDE The CTM CRC aims to improve islet cell transplantation, which may help people with type 1 diabetes survive In a world first, an Australian startup has found a way to commercially manufacture haematopoietic stem cells used in bone marrow transplants. without insulin injections. SPL C R C A . A S N . AU K n ow H ow m a g a z i n e 2 5
  • 27. S O C I E T Y The wider view The 3% of Australians living in remote regions face significant health and social challenges. Two CRCs are finding solutions, writes Fran Molloy. THE PLIGHT OF Aboriginal, Torres Strait Islander and other people living in remote Australia is a “global shame”, warned Dr Tom Calma in November 2014. Calma is Chair of Ninti One, the not-for-profit organisation that manages the CRC for Remote Economic Participation (CRC-REP). More than half a million Australians live in remote areas. Occupying a wide range of climate zones across 80% of our landmass, these regions encompass diverse and rich cultures and unique landscapes. This poses big research challenges for the CRCs working there – primarily the CRC-REP and the Lowitja Institute. Headquartered in Alice Springs, Ninti One has delivered $239 million in social and economic benefits to remote Australia since its inception in 2003. The research is mostly concerned with social good, rather than commercial outcomes, which can make the impact hard to gauge, says Calma. “Research is imperative in order to properly understand and improve the lives of people living in remote Australia,” he says. Calma is a distinguished Aboriginal leader and elder of the Kungarakan people in the Northern Territory. He cites feral camel management as an example of economic good delivered by 26 K n ow H ow m a g a z i n e ISTOCK Aboriginal Community Researcher Amunda Gory with Anmatyerre artist Margaret Scobie. NINTI ONE tool, apply it and then report back on it. This is integral to getting good information.” Calma is a critic of what he calls “fly-in, fly-out bureaucrats” who spend a day or two in a community, speak to a few select people and then leave thinking they have an understanding of the region’s issues. “Our research shows that non-Indigenous or even Indigenous bureaucrats without an understanding of a particular community will come in with preconceived ideas,” he says, adding that this can lead them to frame their questions to get a pre-determined outcome. Aboriginal people then tell bureaucrats what they think they want to hear, or the bureaucrats mistake silence for agreement, Calma explains. Ninti One: 500 rangers were trained to control camel populations and map and maintain waterholes, preventing more than $3 million a year in damage to fences, bores and waterholes in pastoral properties and local communities. Ninti One has invested $1 million in their Pastoral Precision Project, which uses spatial data to match livestock performance to environmental conditions. The product is now ready for market and is expected to benefit many farmers. To assist researchers working on these kinds of projects in remote Australia, Ninti One has produced guidelines in conjunction with community members with protocols around confidentiality, for example. “Sometimes researchers need to understand that they cannot write down all the stories,” says Calma. These also advise where research information and recordings should be kept. Ninti One has trained 90 Aboriginal Community Researchers who live in remote communities to undertake research and surveys in the community. “They have the capacity to understand the language of the community, as well as all the nuances of behaviours within the community,” says Calma. “In working with a client, they can come up with a good survey “Bureaucrats without an understanding of a community will come in with preconceived ideas.”
  • 28. Since its inception in 2003, Alice Springs-based Ninti One has delivered $239 million in economic and social benefits to rural areas throughout Australia. THE CRC PROGRAM is the only Commonwealth initiative providing a link between industry, academia, government and the communities of remote regions, Calma says. “We know from past, bitter experience the policies imposed from on high and afar seldom work well in remote Australia. Only when you truly engage the people who live there do you get results. “At the moment there is evidence that the wellbeing of remote Australians is at increasing risk, and urgent action is needed to reverse this trend and to begin building a more optimistic, prosperous and equitable future for them.” When the CRC analysed employment across remote Australia, they found that a large percentage of jobs were held by non-Indigenous people with a Year 10 or less level of education, despite “more than adequate numbers of Aboriginal people with Year 10 and above qualifications,” says Rod Reeve, Ninti One’s Managing Director. Another significant project, led by Professor John Guenther from Flinders University, aims to identify how education can improve outcomes for Aboriginal and Torres Strait Islander Creating solutions THE HIGHLY SUCCESSFUL Lowitja Institute, established in 2010 as the national institute for Aboriginal and Torres Strait Islander health research, garnered an additional five years of funding in July 2014. The Institute was built on 14 years of CRCs, beginning with the CRC for Aboriginal and Tropical Health in 1997. This CRC introduced a new roundtable process, which set research priorities involving the community as well as researchers and policy-makers – changing the way research into Indigenous health took place. Pat Anderson, Chair of the Lowitja Institute, says the process instituted a new way of commissioning projects, with community leaders at the centre of decision-making. The Institute works collaboratively with stakeholders, building up the research skills of Aboriginal and Torres Strait Island people along the way. “Our guiding principle has always been that, in order to improve our health, we need to create our own solutions rather than have them imposed upon us,” Anderson said at the opening of the Institute’s new offices in October 2014. Preventative health is high on the agenda. The CRC recently evaluated Deadly Choices – a program encouraging Aboriginal and Torres Strait Islander people in southern Queensland to make healthy choices around nutrition, physical activity, smoking and use of harmful substances. The seven-week school and community-based chronic disease prevention and education initiative has grown to encompass at least 1000 children from more than 100 schools and community health programs. While substantial progress has been made in Indigenous people having a greater stake in health service delivery, research and policymaking, Anderson points out there’s a long way to go. “With life expectancy for Australia’s First Peoples still languishing 11 years behind our fellow countrymen and women, we clearly have our work cut out for us.” www.nintione.com.au www.crc-rep.com www.lowitja.org.au C R C A . A S N . AU K n ow H ow m a g a z i n e 2 7 NINTI ONE FIONA HAMILTON PHOTOGRAPHY The Hon Shayne Neumann MP, Ms Patricia Anderson AO and Ms Kelly O’Dwyer MP at the Lowitja Institute. people in remote areas. For the Anangu people in Central Australia, Guenther proposed an academy built around a “red dirt” curriculum covering rural economics, local histories, digital literacies and grammar. The principle behind the academy comes from other projects Ninti One has facilitated, where local and non-local knowledge is shared, and both knowledge systems are treated with equal weight and respect. “We try to look at an issue from many different directions,” Calma says. Calma was formerly Aboriginal and Torres Strait Islander Social Justice Commissioner at the Human Rights Commission, which he points out has some aspects in common with Ninti One. “A human rights-based approach and a community development approach are very similar. They are both about making people the centre of what you do, and we recognise that all our activities are for the constituency of remote Australians.” Head Office Node (Ninti One office) Research Locations Remote Australia
  • 29. FADING VISION At age 40–45, if you find you have to hold a book further away to read it, you may have developed presbyopia: an ageing-related condition in which the eye’s ability to focus on near objects is reduced as its lens progressively stiffens. At this point in life, some people visit an optometrist for the first time. Suddenly they need glasses – and will for the rest of their lives. If Dr Paul Erickson has his way, however, future generations may be heading straight to an ophthalmic surgeon to have a revolutionary ‘accommodating gel’ injected into their eyes. CORNEA IRIS PUPIL LENS B I G P I C T U R E Eye for detail It’s long been accepted that vision declines with age, but an Australian invention could soon change this, writes Clare Pain. 28 K n ow H ow m a g a z i n e FIELD LEADER Originally from Pennsylvania, USA, Erickson has led the accommodating gel project since 2010 with significant funding from the Vision CRC. He is the CEO of Brien Holden Vision Pty Ltd and Adventus Technology Inc – companies through which Vision CRC participant the Brien Holden Vision Institute develops and commercialises its technologies. TEAMWORK ADVANCES Erickson’s team works with the prestigious Bascom Palmer Eye Institute in Florida, USA. The partnership has already led to improved medical microscopic imaging technology for use during the procedure, which could immediately benefit eye surgeons conducting cataract operations, Erickson says. THE SOLUTION The accommodating gel project aims to replace the stiff natural lens with a new lens made from a siloxane gel – a compound of silicone. First, the non-functioning natural lens would be extracted through a procedure similar to surgery for cataracts (lenses which have become opaque). Then, the gel would be injected into the transparent lens capsule. Finding a suitable material to replace the lens has been a 20-year search, says Erickson. The requirements are stringent: it must be a moderately viscous liquid that can be injected, and it must polymerise into a soft, flexible gel. It also has to be biocompatible and, of course, transparent. Developed in Australia, the gel is being trialled in rabbits. “We’re fine-tuning the properties,” says Erickson. “Over the next two to three years, we hope to move into animal models that more closely resemble humans, and then on to human subjects.” DEFINING THE PROBLEM The crystalline lenses in our eyes can adjust their focal length (or ‘accommodate’) by changing shape – bulging or flattening according to the tension in fibres that connect the lens to the circular muscle surrounding the lens capsule. It’s a very flexible lens, but it evolved for a species that lives to around 40 years old, Erickson explains. “During a person’s life, the lens material loses its softness and flexibility, and at around age 40 the loss begins to accelerate,” he adds. “It reaches a point where it’s very difficult for the stiffer lens to change its shape in order to see at a normal reading distance.”
  • 30. Improving STEM MARKET WRAP-UP Key Speakers Professor Ian Chubb Chief SCientiSt of AuStrAliA Education and Skills ’ Aligning education and training with employers needs 11th 12th february 2015, CQ functions, melbourne Leonie Walsh Lead Scientist for Victoria StAte Government of viCtoriA Professor Leon Sterling Pro-Vice Chancellor Swinburne univerSity Innes Willox Chief Executive Officer AuStrAliAn induStry Group Strategies for: improving access to quality Stem education Attracting students into Stem higher education courses Equipping students with the skills and capabilities employers need increasing improving Stem specialised teachers Including industry case studies from Google and IBM SAVE $100 off the current price when you register and quote VIp: CC*KNoWhoW Researched by WorKShopS places are limited! A - How to improve science and mathematics teaching Glenys Thompson, Department of Education and Children’s Services, Government of SA B - How to reduce the gap between education and workforce needs Professor John Yearwood, Federation University Proudly supported by phone 1300 316 882 fax 1300 918 334 registration@criterionconferences.com www.improvingstemeducation.com C R C A . A S N . AU K n ow H ow m a g a z i n e 2 9
  • 31. The spirit within An Innovator’s Wish List Boosting skills Removing barriers Improving finance THE N E X T B I G T H I N G Fairer regulation and better access to finance and equity will give entrepreneurs plenty of encouragement, says Tony Peacock. WE OFTEN HEAR calls for a more entrepreneurial culture. But what does that mean in practical terms? Yes, it is affected by our national psyche, outlook and attitude to risk. We hear that Australians don’t ‘embrace failure’, and that our finance sector is too conservative in its attitude to science and innovation. These opinions might be true, but regardless we also have to get the building blocks right. The ‘next big thing’ might come from a series of small steps in developing the environment for more innovators and entrepreneurs to thrive. The government has just released an Industry Innovation and Competitiveness Agenda, which features a few of the steps that will improve the situation for entrepreneurs in Australia. Issuing share options to employees is an important way of attracting talent. New companies have an idea, a prayer and not much cash. But brilliant young people are often willing to take shares or options in lieu of salaries for a year or two to join the startup entrepreneurial adventure. They might take a very low salary, or spend a year couch surfing or forgoing the benefits of deodorant. The incredible stories of the likes of Twitter, Instagram, Facebook and the rest mean that by taking shares in lieu of salary they may strike it rich. In Australia, rules introduced in 2009 killed off this pathway by demanding that tax be paid on those shares immediately. The government has now fixed that issue. 30 K n ow H ow m a g a z i n e Removing barriers is another important avenue to increase business competitiveness in Australia. Simple things like vaccine companies undergoing identical audits from different regulatory agencies draws cash – and focus – out of the business. The government has decided to have a serious go at lowering those barriers. For the Treasurer’s coming tax review, the Minister for Industry has flagged two more innovations: crowd sourcing of equity finance, and patent boxes. Australia is slow on the equity issue, with the USA, the UK, Canada and New Zealand all ahead of us. But the government has received a very comprehensive report detailing the necessary changes, and action is expected soon. The patent box concept, which started in the UK, allows companies to isolate earnings from patents and have them favourably taxed. Apart from government, financing of innovation is slowly improving. Westpac has provided $50 million to Reinventure, a venture capital company. CSIRO’s new CEO, Larry Marshall, is an Aussie with 25 years of venture capital experience. If the equity-financing model allows self-managed super funds to invest, then who knows the limits? Firing up the entrepreneurial spirit in Australia is the next big thing. The foundations are quickly being laid – next we need the builders to come in. The gap year has become common after senior secondary school. Wouldn’t it be something to see a ‘growth year’, when graduates or postgraduates gave themselves a year to pursue an idea? KnowHow founder Tony Peacock is the CEO of the CRC Association and 2014 Monash University Churchill Fellow at The Winston Churchill Memorial Trust. ISTOCK There are brilliant young people willing to take shares in lieu of salaries to join a startup.