SlideShare une entreprise Scribd logo
1  sur  2
Β oxidation: Fatty acid metabolism
Remember that NADH yields 3 ATP via the electron transport chain. Also remember that FADH2
yields 2 ATP via the electron transport chain. These two values are used to come up with a
value for how much ATP is made via beta oxidation and the TCA cycle.
Palmitic acid. 16 carbon molecule:
First recognize that each fatty acid must be prepared for the beta oxidation process by using 2
ATP to bind it to coenzyme A.
Now, draw the molecule out in two carbon increments.
1 Betaoxidationprocess:
Now count up how many times the molecule undergoes beta oxidation and how many acetyl
coa molecules are formed.
Count up the number of beta oxidation processes: 7
Count up the number of acetyl coa molecules made: 8
Recall that beta oxidation yields 5 ATP
Recall that acetyl coa through the citric acid cycle yields 12 ATP.
Now do some math:
We prepared the molecule for beta
oxidation which cost 2 ATP:
-------------------------------------------------------
There were 7 beta oxidation
processes which yield 5 ATP in each
process:
----------------------------------------------------------
8 Acetyl-CoA molecules were formed
which yield 12 ATP in the TCA cycle:
Cost 2 ATP to prepare fattyacid = -2 ATP
-----------------------
5 ATP* (7 Beta oxidationprocesses) = 35 ATP
-----------------------
12 ATP * (8 Acetyl-CoAmoleculesthroughTCA cycle) =96 ATP
Total ATP from palmiticacid = 129 ATP

Contenu connexe

Similaire à Β oxidation

Energy from fatty acid oxidation
Energy from fatty acid oxidationEnergy from fatty acid oxidation
Energy from fatty acid oxidationLeizel Despi
 
Beta Oxidation By Ali Afzal.pptx
Beta Oxidation By Ali Afzal.pptxBeta Oxidation By Ali Afzal.pptx
Beta Oxidation By Ali Afzal.pptxAliAfzal576752
 
Lecture 3- Oxidation of saturated fatty acids.pptx
Lecture 3- Oxidation of saturated fatty acids.pptxLecture 3- Oxidation of saturated fatty acids.pptx
Lecture 3- Oxidation of saturated fatty acids.pptxArpitaGupte1
 
Citric acid cycle (2)
Citric acid cycle (2)Citric acid cycle (2)
Citric acid cycle (2)Zainab&Sons
 
Beta oxidation and its bioenergetics.
Beta oxidation and its bioenergetics.Beta oxidation and its bioenergetics.
Beta oxidation and its bioenergetics.GCUF
 
Chapter 16 (Part 2).pptx
Chapter 16 (Part 2).pptxChapter 16 (Part 2).pptx
Chapter 16 (Part 2).pptxssuser1d28f41
 
Lipogenesis (Fatty Acid Biosynthesis)
Lipogenesis (Fatty Acid Biosynthesis)Lipogenesis (Fatty Acid Biosynthesis)
Lipogenesis (Fatty Acid Biosynthesis)Leizel Despi
 
beta oxidation of fatty acids
beta oxidation of fatty acidsbeta oxidation of fatty acids
beta oxidation of fatty acidsNehaMahrolia
 
Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)
Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)
Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)Anup Shamsher Budhathoki
 
Oxidation of fatty acids
Oxidation of fatty acidsOxidation of fatty acids
Oxidation of fatty acidsRamesh Gupta
 
De novo synthesis of fatty acids (Biosynthesis of fatty acids)
De novo synthesis of  fatty acids (Biosynthesis of fatty acids)De novo synthesis of  fatty acids (Biosynthesis of fatty acids)
De novo synthesis of fatty acids (Biosynthesis of fatty acids)Ashok Katta
 
bioch 4.pptx
bioch 4.pptxbioch 4.pptx
bioch 4.pptxObsa2
 
Lipid catabolism (fatty acid oxidation)
Lipid catabolism (fatty acid oxidation)Lipid catabolism (fatty acid oxidation)
Lipid catabolism (fatty acid oxidation)Zainab&Sons
 
fatty acid synthesis.ppt
fatty acid synthesis.pptfatty acid synthesis.ppt
fatty acid synthesis.pptSachin Teotia
 
Cellular respiration
Cellular respirationCellular respiration
Cellular respirationsharkyea
 

Similaire à Β oxidation (20)

Oxidation of fatty acids ppt mth
Oxidation of fatty acids ppt mthOxidation of fatty acids ppt mth
Oxidation of fatty acids ppt mth
 
Energy from fatty acid oxidation
Energy from fatty acid oxidationEnergy from fatty acid oxidation
Energy from fatty acid oxidation
 
Beta Oxidation By Ali Afzal.pptx
Beta Oxidation By Ali Afzal.pptxBeta Oxidation By Ali Afzal.pptx
Beta Oxidation By Ali Afzal.pptx
 
Lecture 3- Oxidation of saturated fatty acids.pptx
Lecture 3- Oxidation of saturated fatty acids.pptxLecture 3- Oxidation of saturated fatty acids.pptx
Lecture 3- Oxidation of saturated fatty acids.pptx
 
B oxidation[1]
B oxidation[1]B oxidation[1]
B oxidation[1]
 
Citric acid cycle (2)
Citric acid cycle (2)Citric acid cycle (2)
Citric acid cycle (2)
 
beta oxidation.pptx
beta oxidation.pptxbeta oxidation.pptx
beta oxidation.pptx
 
Beta oxidation and its bioenergetics.
Beta oxidation and its bioenergetics.Beta oxidation and its bioenergetics.
Beta oxidation and its bioenergetics.
 
Chapter 16 (Part 2).pptx
Chapter 16 (Part 2).pptxChapter 16 (Part 2).pptx
Chapter 16 (Part 2).pptx
 
Lipogenesis (Fatty Acid Biosynthesis)
Lipogenesis (Fatty Acid Biosynthesis)Lipogenesis (Fatty Acid Biosynthesis)
Lipogenesis (Fatty Acid Biosynthesis)
 
beta oxidation of fatty acids
beta oxidation of fatty acidsbeta oxidation of fatty acids
beta oxidation of fatty acids
 
Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)
Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)
Fatty acid oxidation ( Beta , Alpha omega and peroxisomal)
 
Oxidation of fatty acids
Oxidation of fatty acidsOxidation of fatty acids
Oxidation of fatty acids
 
De novo synthesis of fatty acids (Biosynthesis of fatty acids)
De novo synthesis of  fatty acids (Biosynthesis of fatty acids)De novo synthesis of  fatty acids (Biosynthesis of fatty acids)
De novo synthesis of fatty acids (Biosynthesis of fatty acids)
 
Ch04
Ch04Ch04
Ch04
 
bioch 4.pptx
bioch 4.pptxbioch 4.pptx
bioch 4.pptx
 
Lipid catabolism (fatty acid oxidation)
Lipid catabolism (fatty acid oxidation)Lipid catabolism (fatty acid oxidation)
Lipid catabolism (fatty acid oxidation)
 
fatty acid synthesis.ppt
fatty acid synthesis.pptfatty acid synthesis.ppt
fatty acid synthesis.ppt
 
Cellular respiration
Cellular respirationCellular respiration
Cellular respiration
 
Glycolysis
Glycolysis Glycolysis
Glycolysis
 

Β oxidation

  • 1. Β oxidation: Fatty acid metabolism Remember that NADH yields 3 ATP via the electron transport chain. Also remember that FADH2 yields 2 ATP via the electron transport chain. These two values are used to come up with a value for how much ATP is made via beta oxidation and the TCA cycle. Palmitic acid. 16 carbon molecule: First recognize that each fatty acid must be prepared for the beta oxidation process by using 2 ATP to bind it to coenzyme A. Now, draw the molecule out in two carbon increments. 1 Betaoxidationprocess:
  • 2. Now count up how many times the molecule undergoes beta oxidation and how many acetyl coa molecules are formed. Count up the number of beta oxidation processes: 7 Count up the number of acetyl coa molecules made: 8 Recall that beta oxidation yields 5 ATP Recall that acetyl coa through the citric acid cycle yields 12 ATP. Now do some math: We prepared the molecule for beta oxidation which cost 2 ATP: ------------------------------------------------------- There were 7 beta oxidation processes which yield 5 ATP in each process: ---------------------------------------------------------- 8 Acetyl-CoA molecules were formed which yield 12 ATP in the TCA cycle: Cost 2 ATP to prepare fattyacid = -2 ATP ----------------------- 5 ATP* (7 Beta oxidationprocesses) = 35 ATP ----------------------- 12 ATP * (8 Acetyl-CoAmoleculesthroughTCA cycle) =96 ATP Total ATP from palmiticacid = 129 ATP