Case Presentation Infectious Diseases

K
Case presentation
B/L Neck swellings
ID Unit - Medicine Dept. - KKUH
Thursday 23rd January 2014
Khalaf Alghamdi, MBBS
History
• N. A. Cairoden
• 21 YO
• Filipino, female
• Student in PNU
• Not known to have any chronic medical illnesses
• Presented to the clinic in 27th Nov. 2013 with 1
year Hx of left neck swellings
• History taken from the patient through translator
History of PC
• Norain was in her usual health state till 1 year
back when she, incidentally, noted a swelling in
the Lt. side of her neck, when she was in Philipin
• Initially, it was only one, small in
size, painless, then another swelling developed
below the old one within few days.
• They got increased gradually in size (like a big
olive) and still constant
• Some times can be felt warm, and occasionally
painful
Contd..
• Seen by doctor in private care center in
Philipin
• Augmentin only was prescribed for her
• Taken for one month
• No relieve
Contd..
• There was NO hx of
– Fever
– Cough
– SOB
– Difficulty in swallowing
– Night sweat
– Rash
– General malaise
– Weight loss
– Joint pain
– Dental infection
– URTIs
– Nausea or vomiting
Contd..
• No hx of previous same complaint
• ,, ,, of same illness in her family members
• ,, ,, of contact with animals
• ,, ,, of sexual relationships
• ,, ,, of using herbal medications
• ,, ,, of travelling before onset of complaint
Contd..
• No past hx of hospital admissions
• No past hx of surgical operations
• No past hx of blood transfusion
• She is not known to has any allergy for
drugs, foods or chemicals
• BCG and HepB virus vaccines taken at
childhood
Contd..
• She is single
• Living with her family in a rented apartment in
Riyadh
• Average economic status
Physical Ex.
• She was looking well, fit
• Oriented to T, P, P
• VS:
• BP=130/80
• HR= 80
• Temp=36.6
• O2 Sat=97% on RA
• Pain score=0
• Tall= 155 cm
• Weight= 50 kg
Physical Ex.
• Neck ex.: There were two visible & palpable masses on
the left side of her neck beside each other, one is
submental (1x2 cm) and the other is lower and smaller
• There is palpable mass on the right side of the neck
less than 1X2 cm
• They were firm, mobile, not fluctuating, not tender, no
sinus or discharge, skin is intact and normal in color
• No other swellings in the neck
• Lymphatic system: no enlarged tonsiles, posterior
cervical, occipital, axillary or inguinal lymph nodes
Physical Ex.
• There was no clubbing
• No signs of dehydration, normal skin color
• Chest: normal and equal breath sounds with
no added sounds
• CVS: normal heart sounds, no added sounds
• Abdomen: soft and lax. No tenderness. No
organomegaly
Investigations
• She was seen previously by occupational
health care and referred to ID clinic
• Labs requested: CBC with
ESR, U&E, HIV, Hep, Preg, VDRL, blood
group, MSU, True cut specimen for AFB and
biopsy
• Chest X-Ray
• Ultrasound
Investigations (CBC & ESR)
Investigations (U&E)
Investigations (HIV & Hep)
Investigations (Preg)
Investigations (VDRL)
Investigations (MSU)
Investigations (True cut AFB)
Biopsy Official Report:
Site of specimen: Lt. cervical lymph node
Type: True cut biopsy
Showed Necrotizing granulomatous lymphadenitis.
Comment: special stain for AFB and GMS are negative. Although
the AFB is negative, the histopathological picture is highly
suspicious for tuberculosis. Clinicopathological correlation is
recommended.
Investigations (Chest X-ray)
Report:
- No focal
parenchymal lung
lesion
-Clear CP angels
- Cardiothoracic
ratio within
normal range
Investigations (US)
Investigations (US)
US Official Report:
Findings: There are multiple bilateral enlarged hypoechoic cervical lymph nodes.
The largest lymph node on the right side measures 0.7 x 0.9 cm and the largest
lymph node on the left side measures 1.8 x 1.0 cm.
Conclusion:
-bilateral cervical lymphadenopathy
-FNA correlation is suggested
Admission
• She was admitted electively under ID team (after
seen in OPD) on Sunday 19th Jan. 2014 for
excisional biopsy
• CBC:
» WBC = 5.4
» HGB = 12
» PLT = 307
» ESR = 51
• MSU = absolutely normal
• U & E = absolutely normal
• Coagulation profile = absolutely normal
Treatment
• On Tuesday 22nd Jan. 2014 Excisional biopsy
done under GA for the left enlarged lymph
nodes only
• Patient has been started on oral ATT as a
guideline of pulmonary TB treatment
• Patient discharged
• Appointment x2/52 for ID OPD for follow up
and LFT & ESR
1 sur 24

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Case Presentation Infectious Diseases

  • 1. Case presentation B/L Neck swellings ID Unit - Medicine Dept. - KKUH Thursday 23rd January 2014 Khalaf Alghamdi, MBBS
  • 2. History • N. A. Cairoden • 21 YO • Filipino, female • Student in PNU • Not known to have any chronic medical illnesses • Presented to the clinic in 27th Nov. 2013 with 1 year Hx of left neck swellings • History taken from the patient through translator
  • 3. History of PC • Norain was in her usual health state till 1 year back when she, incidentally, noted a swelling in the Lt. side of her neck, when she was in Philipin • Initially, it was only one, small in size, painless, then another swelling developed below the old one within few days. • They got increased gradually in size (like a big olive) and still constant • Some times can be felt warm, and occasionally painful
  • 4. Contd.. • Seen by doctor in private care center in Philipin • Augmentin only was prescribed for her • Taken for one month • No relieve
  • 5. Contd.. • There was NO hx of – Fever – Cough – SOB – Difficulty in swallowing – Night sweat – Rash – General malaise – Weight loss – Joint pain – Dental infection – URTIs – Nausea or vomiting
  • 6. Contd.. • No hx of previous same complaint • ,, ,, of same illness in her family members • ,, ,, of contact with animals • ,, ,, of sexual relationships • ,, ,, of using herbal medications • ,, ,, of travelling before onset of complaint
  • 7. Contd.. • No past hx of hospital admissions • No past hx of surgical operations • No past hx of blood transfusion • She is not known to has any allergy for drugs, foods or chemicals • BCG and HepB virus vaccines taken at childhood
  • 8. Contd.. • She is single • Living with her family in a rented apartment in Riyadh • Average economic status
  • 9. Physical Ex. • She was looking well, fit • Oriented to T, P, P • VS: • BP=130/80 • HR= 80 • Temp=36.6 • O2 Sat=97% on RA • Pain score=0 • Tall= 155 cm • Weight= 50 kg
  • 10. Physical Ex. • Neck ex.: There were two visible & palpable masses on the left side of her neck beside each other, one is submental (1x2 cm) and the other is lower and smaller • There is palpable mass on the right side of the neck less than 1X2 cm • They were firm, mobile, not fluctuating, not tender, no sinus or discharge, skin is intact and normal in color • No other swellings in the neck • Lymphatic system: no enlarged tonsiles, posterior cervical, occipital, axillary or inguinal lymph nodes
  • 11. Physical Ex. • There was no clubbing • No signs of dehydration, normal skin color • Chest: normal and equal breath sounds with no added sounds • CVS: normal heart sounds, no added sounds • Abdomen: soft and lax. No tenderness. No organomegaly
  • 12. Investigations • She was seen previously by occupational health care and referred to ID clinic • Labs requested: CBC with ESR, U&E, HIV, Hep, Preg, VDRL, blood group, MSU, True cut specimen for AFB and biopsy • Chest X-Ray • Ultrasound
  • 19. Investigations (True cut AFB) Biopsy Official Report: Site of specimen: Lt. cervical lymph node Type: True cut biopsy Showed Necrotizing granulomatous lymphadenitis. Comment: special stain for AFB and GMS are negative. Although the AFB is negative, the histopathological picture is highly suspicious for tuberculosis. Clinicopathological correlation is recommended.
  • 20. Investigations (Chest X-ray) Report: - No focal parenchymal lung lesion -Clear CP angels - Cardiothoracic ratio within normal range
  • 22. Investigations (US) US Official Report: Findings: There are multiple bilateral enlarged hypoechoic cervical lymph nodes. The largest lymph node on the right side measures 0.7 x 0.9 cm and the largest lymph node on the left side measures 1.8 x 1.0 cm. Conclusion: -bilateral cervical lymphadenopathy -FNA correlation is suggested
  • 23. Admission • She was admitted electively under ID team (after seen in OPD) on Sunday 19th Jan. 2014 for excisional biopsy • CBC: » WBC = 5.4 » HGB = 12 » PLT = 307 » ESR = 51 • MSU = absolutely normal • U & E = absolutely normal • Coagulation profile = absolutely normal
  • 24. Treatment • On Tuesday 22nd Jan. 2014 Excisional biopsy done under GA for the left enlarged lymph nodes only • Patient has been started on oral ATT as a guideline of pulmonary TB treatment • Patient discharged • Appointment x2/52 for ID OPD for follow up and LFT & ESR