6. Arachnoid granulations: This is where the CSF produced in the choroid plexuses of the ventricles and which has circulated into the subarachnoid space is reabsorbed. Longitudinal fissure
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10. Cervical Enlargement Gray matter expanded to incorporate more sensory input from limbs and more cell bodies for motor control of limbs
12. Spinal Meninges 3) Pia mater 2) Arachnoid 1) Dura mater Three membranes surround all of CNS 1) Dura mater - "tough mother", strong. Note the Epidural Space. 2) Arachnoid - spidery looking, carries blood vessels, etc. Note the Subarachnoid space which contains CSF 3) Pia mater - "delicate mother", adheres tightly to surface of spinal cord 2a) Subarachnoid Space
13. Transverse Section Fig 13.30 Compare the spinal roots with the model of the vertebral column in the lab. Note that the dura covers both the dorsal and ventral roots.
16. Lumbar Puncture (= Spinal Tap) For clinical examination of CSF or administration of radiopaque dyes, drugs and anesthetics However: mostly “epidurals” for anesthetics L3 S1
Buoyancy : brain weight in air: about 1.4 kg – in CSF about 50 g (= 97% lighter) because it is only a little denser than the CSF. Protects brain from crushing itself. Arachnoid granulations only appear at about 3 years of age. Infants are therefore especially sensitive to alterations or hyperactivity of the choroid plexuses.l
Alcohol, nicotine and anesthetics can diffuse through BBB. Blood borne toxins (urea, food toxins, bacterial toxins) cannot get through. Recent discovery: During prolonged emotional stress the tight junctions of the BBB are opened.
31 pairs of spinal nerves – designated as are vertebrae a. 8 cervical b. 12 thoracic c. 5 lumbar d. 5 sacral
do NOT require cerebral processing but can be modified by cerebral control