Data Quality- How to clean up your legacy data

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Common data issues in legacy data

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Data Quality- How to clean up your legacy data

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The Fast Track to Fair Lab Data

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Speak in common terms – identify Business Outcomes (value) as well as technology Don’t say “semantics”, “FAIR”, “ontologies”, etc. – talk about outcomes and results Drive projects through results – QUICK WINS Identify the right data – build off of that (evolution not revolution) Think about legacy systems, provenance, governance, stewardship, etc. – have answers to the nay-sayers. Be honest what this will do and what it won’t ROI – have this in mind (Business Value not Tech Value) Cost savings (reduced hours, faster search, accurate reporting, better visibility, etc.) Risk Mitigation (improved regulatory, corporate knowledge vs. indivual, M&A, etc.) Innovation (what is the value to being a thought leader?)

Challenges & Opportunities of Implementation FAIR in Life Sciences

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This talk will provide a means to discuss the capture, integration and dissemination of data across large enterprises. We will show how data variety is continuing to grow, meaning new data sources are steadily becoming available for use in analysis. Data veracity is also of importance since a large amount of data is fuzzy (uncertain) in nature. The ability to integrate these various data sources and provide improved capabilities to understand and use it is of increasing importance in today’s pharma climate. We call this Reference Master Data Management (RMDM). This talk will span an arc of data lifecycle management, beginning with instrument data, moving across to clinical studies, production, regulatory affairs and finally e-archiving (see Fig. 1). I will show how these systems can use a common semantics for modeling of important metadata, which can apply the FAIR principles of Findability, Accessibility, Interoperability and Reusability to a common “semantic hub” that can connect data sources of different varieties across the enterprise. ADF files, for example, use their Data Description layer to provide semantic metadata about file contents. Similarly, semantics can be used to describe clinical trials data, regulatory data, etc., through to archiving, for improved storage and search over long periods of time.

Data lifecycle mgt across the enterprise

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We will present the updated Allotrope framework and cover .adf files and how they are used. We’ll demonstrate semantic modeling in .adf (OWL models + the SHACL constraint language). We’ll show how the data description layer in .adf can be extended via a “semantic hub” that we call Reference Master Data Management, which can be used across the enterprise. RMDM provides a means to integrate metadata about any data source within your enterprise – including structured, semi-structured and unstructured data. Customer examples from current project work will be given where possible. Last we’ll show scalability of this approach using data science techniques can be employed beyond just the metadata – we refer to this as Big Analysis.

From allotrope to reference master data management

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Big Data becomes Big Analysis

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Early AI Adoption Via Advanced Analytics

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The world is changing at a rapid pace. New varieties of data continue to spring up and be made available for integration and knowledge improvement across many domains. Knowledge engineering, using advanced techniques in data science, is therefore moving to the forefront of technology and IT concerns at many companies. We see this in the expansion of cloud technologies, semantic technologies, data analytics, and the construction of Data Lakes. Understanding one’s data and being able to derive complex patterns of interest from across a multitude of different data sources (public and private) should be of paramount concern for companies in the pharmaceutical, crop science and life science industries. Companies who embrace knowledge engineering practices will possess a distinct advantage in the coming years due to their ability to integrate and use data to their advantage. This talk will discuss recent trends in data science and will highlight some of the main points to consider for taking advantage of these new technologies and approaches. We will also cover certain lessons learned from real-world industry use cases to highlight how people are using these technologies for improved business benefits.

Why Data is Becoming the Most Valuable Asset Companies Posses

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• Big Data technologies, especially Data Lakes are spreading across many industries at the moment with the hopes that they will provide unprecedented capabilities for data integration and data analytics • In spite of the popularity and promise of these technology approaches, many early adopters are not seeking immediate solutions to their complex problems. Answers are not simply appearing – this talk will explore this issue more thoroughly • Of the 4 V’s of Big Data, Data Variety and Data Veracity (uncertainty) are of increasing importance. These can cause barriers to successful integration strategies , which, in turn, can lead to poorly performing analytics. • The problems of Variety and Veracity can be tackled using a new form of Data Science which combines formal ontologies with statistical heuristics. This talk will explore some key features of these approaches and how they can be developed together in symbiosis – leading to complex models that allow for improved analytics – or as we call it Big Analysis. • The end result is improved capture of data types/sources, from laboratory instrument data, to clinical data, to regulatory rules & submissions, all the way to business drivers for the enterprise. In the end providing advanced analytics capabilities that can be built as modules and expand across an enterprise.

Reinventing Laboratory Data To Be Bigger, Smarter & Faster

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The Allotrope Foundation is a consortium of major pharmaceutical companies and a partner network whose goal is to address challenges in the pharmaceutical industry by providing a set of public, non-proprietary standards for using and integrating analytical laboratory data. Current challenges in data management within the pharmaceutical industry often center around inconsistent or incomplete data and metadata and proprietary data formats. Because of a lack of standardization, several operations (e.g. integration of instruments/applications, transfer of methods or results, archiving for regulatory purposes) require unnecessary efforts. Further, higher level aggregation of data, e.g. regulatory filings, that are derived from multiple sources of laboratory data are costly to create. These unnecessary costs impact operations within a company’s laboratories, between partnering companies, and between a company and contract research organizations (CROs). Finally, the accelerating transition of laboratories from hybrid (paper + electronic) to purely electronic data streams, coupled with an ever-increasing regulatory scrutiny of electronic data management practices, further require a comprehensive solution. This talk will discuss how The Allotrope Foundation is providing a new framework for data standards through collaboration between numerous stakeholders.

Revolutionizing Laboratory Instrument Data for the Pharmaceutical Industry:...

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In our webinar on Jan 17th, 2017, Eric and Heiner gave attendees insights on the following: 1. What semantics are (model/data separation, graphs, apply better meaning to data, etc.) 2. Why you should consider using these technologies (real world examples of benefits our customers are seeing) 3. How to pick the right tech for your needs (provide a description of the types of graph/RDF stores out there – we have a matrix based on features – and show how various SPARQL queries work against legacy data.)

Demystifying Semantics:Practical Utilization of Semantic Technologies for Rea...

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Life science’s main asset is its data. Data forms the basis of scientific decision making and its availability via electronic systems is a prerequisite for collaborative work and successful innovation. While more data is published as linked (open) data, huge amounts of data remain unused in internal data silos, such as various ELN’s, because of substantial integration efforts and data quality issues. Since the overwhelming amount of data is unstructured, information extraction and corresponding classification and semantic labeling of content is required. To generate value from your ELN data, a solid informatics strategy is needed to ensure data quality and streamline analytics. Semantic technologies are key enabler to overcome existing limitations.

Why paperless lab is just the first step towards a smart lab

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Smart Data for Smart Labs

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Allotrope Foundation & OSTHUS at SmartLab Exchange 2015: Update on the Allotr...

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Plus de OSTHUS (13)

The Fast Track to Fair Lab Data

Challenges & Opportunities of Implementation FAIR in Life Sciences

Data lifecycle mgt across the enterprise

From allotrope to reference master data management

Big Data becomes Big Analysis

Early AI Adoption Via Advanced Analytics

Why Data is Becoming the Most Valuable Asset Companies Posses

Reinventing Laboratory Data To Be Bigger, Smarter & Faster

Revolutionizing Laboratory Instrument Data for the Pharmaceutical Industry:...

Demystifying Semantics:Practical Utilization of Semantic Technologies for Rea...

Why paperless lab is just the first step towards a smart lab

Smart Data for Smart Labs

Allotrope Foundation & OSTHUS at SmartLab Exchange 2015: Update on the Allotr...

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