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BACTERIA: Cocci
By: Agusan, Almeida, Amador, Arboleda, Artates
Report Overview:
Cocci
1. Staphylococci
a. Staphylococcus aureus
b. Staphylococcus epidermidis
c. Staphylococcus saprophyticus
2. Streptococci
a. Alpha hemolytic
b. Beta hemolytic
c. Gamma hemolytic
Cocci
A coccus (plural: cocci, meaning berries) is a spherical-shaped gram
positive bacteria. It is usually round but also comes as oval,
elongated, or flattened on one side.
Cocci
Cocci divide to reproduce, and they can remain attached to
one another after the binary fission.
❑ Diplococci are those that remain in pairs
after dividing.
❑ Streptococci are attached in a chainlike
pattern.
❑ Cocci that are divided into two planes and
remain in groups of four are known as
tetrads.
❑ Those that divide in three planes and
remain attached in cubelike groups of
eight are called sarcinae.
❑ Staphylococci are those that are divided in
multiple planes and form grapelike
clusters or broad sheets.
1. Staphylococci
Staphylococcus (sometimes called staph) is a genus of
Gram-positive bacteria that can cause various infectious
disease in the different tissues of the body. Staph-related
illness can range from mild and requiring no treatment to
severe and potentially fatal.
The name Staphylococcus comes from the Greek word
“staphyle,” which means a bunch of grapes, and “kokkos,”
meaning berry.
a. Staphylococcus aureus
It is called “aureus” because of its color, the word was derived from
the Latin word “aurum,” which means gold
It is a catalase positive and coagulase positive cocci
It is considered as the most important human pathogen
Its normal flora is commonly found in the anterior nares
Methicillin-resistant Staphylococcus aureus (MRSA) is one of its
strains that is found to be very difficult to treat because of its
resistance to the antibiotic methicillin
MSA
Rapid enzyme tests
´Rapid enzyme tests detect the presence of the following enzymes:
´(1) Catalase breaks down hydrogen peroxide.
´This test is used to differentiate the genus Staphylococcus (catalase-positive) from
Streptococcus (catalase-negative).
´ In general, many anaerobes (and some microaerophiles) do not make catalase
(2) Oxidase (cytochrome-C oxidase) is produced by most Gram-negative bacteria but
not by members of the Enterobacteriaceae. Oxidase-positive rules the latter out.
(3) Nitrate reductase reduces nitrate to nitrite.
It is used to detect the presence of Enterobacteriaceae in urine
a)Escherichia coli and other enterobacteria produce nitrate reductase; this test
requires that the bacteria remain in contact with the urine for a sufficient time.
b)Staphylococcus saprophyticus does not produce nitrate reductase.
Clinical Manifestation
1. Inflammatory
✔Skin and soft tissues infection
Stye Folliculi
tis
Impetig
o
Carbunc
le
✔Heart
✔Lungs
Acute Bacterial
Endocarditis
Staphylococcal
Pneumonia
✔ Bones/Joints
Osteomyelitis
Septic Arthritis
2. Toxin-mediated
Toxic Shock
Syndrome
Staphylococcal
Scalded Skin
Syndrome or
Ritter’s Disease
b. Staphylococcus
epidermidis
It is the most common contaminant of lab samples and medical
devices.
Its normal flora is usually found on the skin and has a white pigment
It is catalase positive and coagulase negative
It is also sensitive (susceptible) to novobiocin.
It is a significant cause of bacterial sepsis
Clinical Manifestation
Infections secondary to implants & prosthetic devices, catheters and
shunts.
c. Staphylococcus
saprophyticus
It is a catalase positive and coagulase negative
novobiocin resistant
It has a bright yellow pigment or white pigment
S. saprophyticus is part of the normal human flora that colonizes the
perineum, rectum, urethra, cervix, and gastrointestinal tract.
Clinical Manifestation
Urinary Tract
Infection
2. Streptococci
Streptococci bacteria got its name from the Greek streptos
(“chain”) + kokkos (“berry”)
Streptococci are gram-positive spherical bacteria. Unlike
staphylococci, streptococcal cells usually grow in chains.
Streptococci are catalase negative.
It is categorized as alpha-hemolytic, beta-hemolytic, and
gamma-hemolytic streptococci
a. Alpha Hemolytic
1. Streptococcus pneumonia
▪They are optochin sensitive
▪It is “lancet” shaped
▪Quellung reaction positive: capsular swelling
▪May appear as small, grey, moist (sometimes mucoidal)
Clinical Manifestation
M-O-P-S
• Meningitis
• Otitis media
• Pneumonia (Adult)
• Sinusitis
Meningitis
Otitis Media
Pneumonia
Sinusitis
II. Viridans Streptococci
▪Viridans streptococci are part of a normal oral flora
▪It is catalase negative
▪Resistant to optochin
•The term viridans derives from the Latin word viridis,
meaning “green”
•Streptococcus mutans
Clinical Manifestation: Dental carries
•Streptococcus sanguanis
Clinical Manifestation: Subacute bacterial endocardidtis in
diseased valves
Group A – Streptococcus pyogenes
▪It is catalase negative
▪Sensitive to bacitracin
▪Pyogenes – “pus producing”
b. Beta Hemolytic
1. Pharynx: Pyogenic-pharyngitis (Sore throat)
Clinical Manifestation
2. Soft Tissue
Cellulitis
Impetigo
3. Toxigenic infection:
Scarlet fever
Necrotizing fasciitis
Toxic Shock Syndrome
3. Immunologic:
Rheumatic fever:
Rheumatic Heart Disease (RHD)
Acute Glomerulonephritis (AGN)
Group B – Streptococcus agalactiae
▪Catalase negstive
▪Bacitricin resistant
▪Agalactiae –”no milk”
Neonatal sepsis and meningitis
Clinical Manifestation:
Enterococci Group:
Enterococcus faecalis & Enterococcus faecium
▪Common cause of nosocomial infections
▪Can grow in bile
▪ Can grow in 6.5% NaCl
▪Often grouped in pairs (diplococci)
▪Normal flora: GI Tract
▪Found in feces
c. Gamma Hemolytic
▪Bacteremia
▪Endocarditis
▪Meningitis
▪Periodontitis
▪Urinary tract infections
▪Wound infections
Clinical Manifestation:
Non Enterococci group
Streptococcus bovis
▪Can grow in bile
▪Cannot grow in 6.5% NaCl
▪Normal flora is found in the digestive system
▪Bacteremia
▪Endocarditis
▪Colorectal Cancer
Clinical Manifestation:
References:
www.mayoclinic.org
www.healthline.com
www.msdmanuals.com
www.health.state.mn.us
www.radiologykey.com
www.ncbi.nlm.nih.gov
www.youtube.com/watch?v=ZxlP_dMPRXc
www.emedicine.medscape.com/article/169177-overview
www.cdc.gov
www.hopkinsmedicine.org
www.youtube.com/watch?v=sCQQsJCZEVI
www.biologyonline.com
www.frontiersin.org

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Cocci Bacteria