vitamin D3

1. Vitamin D3

2. Vitamin D3

3. Calcium regulation

4. Vitamin D3 roles

5. Vitamin D3 level
Deficiency
Insufficient
Optimal

6. Vitamin D3 deficiency
In children
Growth retardation
Rickets

7. Vitamin D3 supplement
Osteoporosis
 Rickets
CV disease
Psoriasis
Diabetes mellitus
Therapeutic uses
Hyperparathyroidism
Hypoparathyrodism
Inflammatory bowl disease
Rheumatoid arthritis
 Malignant neoplasms

8. Vitamin D3 supplement
CV . Disease
Renal disease
Ectopic calcification
Hypercalciuria
hyperphosphataemia
Nausea & vomiting
Anorexia
Polyuria
Diarrhea
constipation
Side effect Overdose

9. Vitamin D3 supplement
Precautions
1- Hypercalcaemia 2- renal impairment
3- infant 4- heart disease
Pregnancy and breastfeeding
1- Use with caution
2- monitoring phosphate concentration

10. Vitamin D3 supplement
Nutritional supplement
 0-12 months: 400 IU (10 mcg) PO once daily
 1-70 years: 600 IU (15 mcg) PO once daily
 >70years: 1000 IU (25 mcg) PO once daily
Resistant rickets
 12,000-500,000 IU (0.3-12.5 mg) PO once
daily
Hypoparathyroidism
 50,000-200,000 IU (0.625-5 mg) PO once
daily with calcium supplements

11. M.s