RESPONSE TO ALTERED INTEGUMENTARY FUNCTION
Unit Outcomes: Upon completion of this unit of study, the student will be able to:
• Safe Effective Care Environment:
• 1. Identify factors that influence injury and disease prevention ( sun exposure, environmental toxins, etc.).
• 2 . Perform thorough dermatological assessment throughout the life span.
• Health Promotion and Maintenance:
• 3. Identify healthy behaviors by the client and family ( screening exams, limiting risk taking behaviors).
• Psychosocial Integrity:
• 4. Discuss psychosocial impact of client’s altered dermatological condition ( acne, burns, rashes, tumors).
• Physiologic Integrity:
• 5. Discuss nursing implications for medications prescribed for clients with dermatologic disorders.
• 6. Develop plan of care for client with impaired skin integrity.
• 7. Explain the eight parameters of assessing a lesion.
• 8. Describe common lesions and rashes utilizing proper terminology.
• 9. Describe pre-op and post care of clients receiving dermatological surgical procedures.
• 10. Select nursing diagnoses most likely to be utilized with clients with integumentary problems.
• 11. Discuss etiology, clinical manifestations, and interventions for viral, bacterial, fungal, and parasitic skin
disorders.
Thorough History
• Dx & Tx – realm of practice
– Difficult due to similarities in lesions and sx
• Differential dx requires clues
Assessment: Subjective Data
– Past Medical History
• Trauma
• Surgery
• Prior skin disease
• Jaundice
• Delayed wound healing
• Allergies
• Sun exposure
• Radiation treatments
Assessment: History
• Surgery
– Cosmetic
– Biopsy
• Diet
• Health Practices
– Hygiene, products
– Sunscreen, SPF
– Complementary &
alternative medicine
• C/O symptoms
• Known exposure to
carcinogens, chemical
irritants, allergens
• Family
– Alopecia (bald)
– Psoriasis
– Skin cancer
• Privacy
• Carefully describe:
– Obvious changes in color and vascularity
– Presence or absence of moisture
– Edema
– Skin Lesions
– Skin integrity
• Document properly
Assessment
Parameters of General Skin Assessment
• color, temperature, moisture, elasticity,
turgor, texture, and odor.
Assessment: Inspection
• Consider Cultural and Ethnic variations
– Dark skin
• rates - skin cancer
• Difficult to assess flushing; cyanosis; jaundice
• Rashes difficult to observe
• Pseudofolliculitis
• Keloids
• Mongolian spots
• Inspection of hair
– Distribution
– Texture
– Quantity
• Inspection of nails
• Iggy page 474-475; Wilkinson 370
– Grooves
– Pitting
– Ridges
– Curvature
– Shape
Malnutrition
Anorexia nervosa
Anxiety
Hygiene
Depression
Hormones
Living conditions
Circulatory status
Chronic disease
Assessment: Inspection
Lesion Description
• Size
– Metric
• Shape
– Circumscribed
– Irregular
– Round
• Texture
– Rough
– smooth
• Configuration
– Annular
• “relating to, or
forming a ring”
– Linear
– Concentric rings
– Clustered
– Diffuse
• Effect of pressure
Lesion Description
• Distribution
– Asymmetric vs. Symmetric
– Confluent
• “flowing or coming together; also : run together”
– Diffuse
– Localized
– Solitary
– Zosteriform
• “resembling shingles”
– Satellite
Assessment: Palpation
– Edema
– Moisture
– Temperature
– Turgor
– Texture
Fever
C-V status
Respiratory status
Hormones
Hydration
Rash/ Lesion
Nutritional status
Skin cancer - most common cancer!
• Risk factors
– Fair skin
– Blue/green eyes
– Blond/red hair
– History chronic sun exposure
– Family history
– Living near the equator
– Very high/low altitudes
– Working outdoors
– Age > 60 (damage is cumulative)
Non-melanoma Skin Cancers
• Basal Cell Carcinoma
– Most common type of skin cancer
– Easily treated
– Doesn’t metastasize
– Middle age to older adults
– Symptoms
• Small slow growing papule
• Semi translucent or “pearly”
• Erosion/ulceration of center
Non-Melanoma Skin Cancer
• Squamous cell
– Less common than BCC
– High cure rate with early detection
– Can be aggressive, metastasize & be fatal
– Common on lips, mouth, face and hands
• Pipe, cigar, & cigarette smoking
– Symptoms
• Firm nodule
• Scaling/ulceration
• Opaque
Squamous cell carcinoma
Medical Tx
• Excision
• Radiation
• Moh’s surgery
(see slide #33)
• 5 FU or methotrexate intralesional
– (see slide #34)
Diagnostic & Surgical Therapy
• Simple Excision
• Excision
– Moh’s micrographic surgery
• Microscopically controlled removal of lesion
• Removes tissue in thin layers
• Can see all margins of specimen
• Preserves normal tissue
• Produces smallest wound
Drug Therapy: Topical Fluorouracil (5-FU)
– Selective toxicity for sun damaged cells (cytotoxic)
– Indications
• Premalignant skin disease (esp. actinic keratosis)
• Systemic absorption minimal
It causes painful eroded area within 4 days and must
use 1-2 times daily 2-4 weeks.
Healing up to 3 weeks after med stopped
Is photosensitizing - avoid sunlight during treatment
Will look worse before it gets better
Non-Melanoma Skin Cancers
• Actinic Keratosis (AKA Solar keratosis)
– Most common precancerous lesion
– Premalignant form of squamous cell carcinoma
– Symptoms
• Hyperkeratotoc papules/plaques on sun exposed areas
• Varied appearance
– Irregular shape
– Flat
– Indistinct borders
– Overlying scale
Actinic Keratosis
(AKA Solar keratosis)
Medical Tx:
•Cryosurgery
(see slide #37)
•5 FU
•Surgical removal
•Retin A
•Chemical peels
Cryosurgery
– Subfreezing temps for surgery (liquid nitrogen)
• Lesion becomes red & swollen, blisters, then scabs; falls off
in 1-3 weeks
• Minimal scarring
– Indications
• Genital warts
• Seborrheic keratosis
• Actinic keratosis
Malignant Melanoma
• 1/3 of all melanoma occur in existing nevi
or moles
– Any sudden or progressive change in size,
color or shape of a mole should be checked
Malignant Melanoma
• Can metastasize anywhere
• Most deadly of skin cancers
• Causes
– UV radiation
– Skin sensitivity
– Genetic
– Hormonal
– Sun exposure
– Mutation of gene (B-RAF) 70%
A B C D’s of Melanoma
Asymmetry
Border irregular, edges ragged
Color varied pigmentation
• Tan, brown, black, red
Diameter > 6mm
Melanoma
Medical Tx
Depends on site, stage, age and
general health of client
– Surgery
– Chemotherapy
– Biologic Therapy
• Interferon, interleukin
– Radiation therapy
Sunburn: Education
(Protect, Protect, Protect)
• Same precautions as for skin cancer.
• Don’t let clouds or cool air fool you –
Florida sun is damaging then too.
• Get out of the sun before you turn red!
• Cool skin off. Immediately!
• Hydrate!
Sunburn
• Superficial burn
• Excessive exposure to ultraviolet rays injures
dermis.
• Dilated capillaries = red, tender, edema,
blisters
• Large area = nausea, fever
Sunburn
• Redness & pain begin within a few Hours.
• Intensity may increase before subsiding.
• 3-5 days to heal
• Tx: cool bath; soothing lotions; topical
corticosteroids; fluids
Infestations: Pediculosis
– Head, body or pubic lice (“crabs”)
– Parasite excrement and eggs on skin
– Nits in hair
• Waxy, don’t fall off easily
• Symptoms
• Tiny red points to papular wheal-like lesions
• Pruritis – check hairline
• Secondary excoriation
Infestations: Scabies
– Skin reactions due to eggs, feces, & mite parts
– Transmitted by direct contact
• Symptoms
– Severe itching especially at HS
– Usually not on face
– Presence of burrows esp. interdigital webs & flexor
surface of wrists
– Redness, swelling, vesiculation
Scabies
Medical tx
– Topical Scabicide
– Antibiotics for 2ndary
infection
– Treat those in close
proximity
– Clothing & linens – hot
water and detergent
Plants in FL that irritate skin
• Poinsettia, Croton
• Milky sap can cause skin irritation
• Oleander
– Touching the plant is not dangerous, but prolonged contact can
irritate the skin.
• Poison Ivy , Brazilian Pepper
– Touching the leaves or oil from the plant can cause an itchy rash
with blisters.
Drug Therapy
• Topical Corticosteroids
– Anti-inflammatory, antipruritic
• Low potency (hydrocortisone)
– Slower acting
– Can be used longer without serious side effects
– Ointment most efficient
– Higher potency, long term, systemic use is different tx
– Intralesional
• Reservoir of med effects lasts several weeks to months
• Indications
– Psoriasis
– Alopecia
– Cystic acne
– Hypertrophic scars and keloids
– Systemic
• Undesirable adverse effects – Lilley 6th ed. Page 869
• Short term therapy – poison ivy
• Long term therapy – chronic bullous diseases
Corticosteroids
Triamcinolone (Kenalog)
Bases for Topical Medications
• Powder
– Promotes dryness
– Good for antifungals
• Lotion
– Cooling and drying with residual powder film
– Good for pruritic eruptions
• Cream
– Emulsion of oil and water
– Lubrication and protections
• Ointment
– Oil with water in suspension
– Lubrication
– Most efficient delivery system
• Paste
– Mixture of powder and ointment
– Drying
– Moisture absorption
Nursing Management: itch
• Baths
– For large body areas
– Has sedating and antipruritic effect
– Oilated oatmeal (Aveeno), potassium permangenate,
sodium bicarb
– Temp comfortable to client
– Soak 15-20 mins 3-4 times daily
– Pat dry, no rubbing
– apply moisturizers or meds after baths
Nursing Management
• Wet dressings
– Indications
• Skin weepy from infection/inflammation
• Relieves itching
• Debrides wound
• Increases penetration of topical meds
• Relieves discomfort
• Enhances removal of scabs, crusts, and exudate
Wet dressings
Procedure
•Clean solution and gauze
•Squeeze until not dripping
•Apply to affected area, avoid normal tissue
•Leave in place 10-30 minutes 2-4 times a
day
•Discontinue if skin macerates (“to soften”)
Dermatological Interventions
• Phototherapy
– UVA & UVB (UVL)
– Ultraviolet wavelengths cause erythema,
desquamation, and pigmentation
– Enhance with psoralem (photosensitizing)
• Treatment for
• Psoriasis
• Atopic dermatitis
• Vitiligo
Phototherapy
• Adverse effects
– Basal or squamous cell Ca
– Burns
– Erythema
– Teach patients to avoid further sun exposure &
photosensitizing drugs
– Wear eye protections as psoralem absorbed by lens of eye
Dermatological Interventions
• Radiation Therapy
– Indications
• Cutaneous malignancies
– Advantages
• Produces minimal damage to surrounding tissues
– Adverse effects
• Permanent hair loss (alopecia) to irradiated areas
• Telangiectasia
• Atrophy
• Hyperpigmentation / depigmentation
• Ulceration
• BCC and SCC
y.
Diagnostic & Surgical Therapy
• Skin Scraping
– Scalpel
– Surface cells for microscopic inspection
• Electrodesication & electrocoagulation
– Electrical energy converted to heat
– Destroys tissue by burning
• Coagulates bleeding vessels
• Curettage
– Remove tissue with circular cutting edge
– Small skin tumors
• warts, seborrheic keratosis, BCC, SCC
Allergic Conditions
• Contact Dermatitis
– Delayed hypersensitivity
– Lesions 2-7 days after antigen exposure
• Manifestations
– Red, hive-like papules and plaques
– Sharply circumscribed
– Vesicles
– Pruritic
Contact Dermatitis
Medical Tx
– Topical corticosteroids
– Antihistamines
– Skin lubrication
– Elimination of allergen
– Systemic steroids if
severe
http://dermatology.cdlib.org/DOJvol7num1/NYUcases/contact/joe.html
Drug Therapy: Antihistamines
• Compete with histamine receptor site
– Oral or Topical
• Cetitizine (Zyrtec)
– PO tabs, syrup QD
– Non-sedating
• Diphenahydramine (Benadryl)
– PO, IM, topical
• Indications
– Urticaria
– Pruritis
– Allergic reactions
Drug Therapy: Antihistamines
• Adverse effects
– Anticholinergic
– Sedation (Benadryl)
– Use with caution in older adults
• Indications
– Urticaria
– Pruritis
– Allergic reactions
• Adverse effects
– Anticholinergic
– Sedation (Benadryl)
– Use with caution in older adults
Allergic Conditions: Drug Reaction
• Manifestations
– Rash of any morphology
– Red, macular, papular
– Generalized rash with sudden onset
– Pruritic
– Can occur as late as 14 days after drug is stopped
Allergic Conditions: Atopic Dermatitis
– Cause unknown
– Begins in infancy and declines with age
• Manifestations
– Scaly, red to re-brown, circumscribed lesions
– Pruritic
– Symmetric eruptions
Atopic Dermatitis
– Topical corticosteroids
– Phototherapy
– Coal tar
corticosteroids
– Lubrication of dry skin
– Antibiotics for secondary infections
Medical Treatment
Dysplastic Nevus Syndrome
• Abnormal mole pattern
• Increased risk for melanoma
– Doubles with dysplastic nevi
• Atypical moles larger than usual (>5mm)
• Irregular borders, possibly notched
• Various variegated colors
• Most common on back
Infections of the skin
• Risk factors
– Imbalance between host and microorganism
– Broken or damaged skin; Trauma
– Systemic disease such as Diabetes
– Moisture
– Obesity
– Systemic corticosteroids, antibiotics
• Prevention
– Proper hygiene
– Good health
Infections: Herpes Simplex Virus, Type I
(AKA “cold sores/fever blisters”)
• Contagious
• Dormant – Exacerbation
• Triggers
• Symptoms -- 1st episode 3-7 days after exposure
– Painful local reaction
– Vesicles on erythematous base
– Fever, malaise
Herpes Simplex Virus, Type I
Medical Tx
– Symptom management
– Moist compresses
– Petrolatum to lesions
– Antiviral agents (Zovirax,
Famvir, Valtrex) www.treatmentsforhealth.com/.../cold-sores/
Infections: Herpes Simplex Virus, Type II
– Genital
“Most genital herpes is caused by HSV-2.” (n.l.m.-n.i.h./ Medline plus)
– Recurrence more common than oral
• Does not mean re-infection
• Symptoms
– Same as Type I
• Treatment
– Same as Type I
Iggy page 1742-1743
Infections: Herpes Varicella Virus
(chicken pox)
** Highly contagious
• No chicken pox or vaccination
• Keep those w/active lesions separated until crusted
• Symptoms
– Vesicular lesions in successive crops
• Face , scalp, spreading to trunk and extremities
Protect eyes
Do not squeeze pustules or crusts
• Vesicles > pustules > crusts > scars
• Postherpetic neuralgia
• Self limiting in children
Infections: Herpes Zoster
(shingles)
– Activation of varicella zoster virus
– Frequent occurrence in immunocompromised
– Potentially contagious to immunocompromised
• Symptoms
– Linear patches along dermatome
– Grouped vesicles on erythematous base
– Unilateral on trunk
– Burning pain and neuralgia
Drug Therapy: Acne Preparations
– Isotretinoin (Accutane)
• Pregnancy Category X
– Proven teratogen
– 2 contraceptive methods
– Tretinoin (Retinoic acid, Vitamin A acid, Retin-A)
• Stimulates epidermal cell turnover -> skin peeling
• Adverse effects
– Red edematous blisters, crusted skin, altered skin
pigmentation
• Avoid sun, use sunscreen
• Apply to dry skin
Benign Skin Conditions: Moles
Grouping of normal cells
• Manifestations
– Hyperpigmented areas
– Varying form and color
• Treatment
– None necessary
– Cosmetic
– Biopsy for diagnosis
Benign Skin Conditions
• Psoriasis
– Chronic dermatitis due to rapid turnover of epidermal cells
– Family predisposition
– Manifestations
– Sharply demarcated scaling plaques of
• Scalp
• Elbows
• Knees
• Palms, soles, and fingernails possible
• Treatment
– Retard growth of epidermal cells
– Topical corticosteroids
– Tar
– Anthralin topical
– Sunlight, UV light
– Alefacept (Amevive) injection
– Antimetabolites (methotrexate) or systemic retinoids for difficult
cases
Benign Skin Conditions
• Seborrheic Keratoses
– Irregularly shaped flat topped papules or
plaques
– Warty surface
– Appearance of being stuck on
– Increase in pigmentation
– No association with sun exposure
– Treatment
• Removal
– Curettage
– cryosurgery
Benign Skin Conditions: Lipoma
Encapsulated tumor of adipose tissue
Most common 40-60 years of age
• Manifestations
– Rubbery, compressible, round mass
– Variable in size
– Most common on trunk, back of neck, forearms
• Treatment
– Biopsy
– Excision if indicated
Benign Skin Conditions: Vitiligo
– Unknown cause
– Genetic connection
– Complete absence of melanocytes
– Non-contagious
• Manifestations
– Complete loss of pigment
– Variation in size an location
– Symmetric and permanent
• Treatment
– Exposure to UVA and psoralens
– Depigmentation of pigmented skin in extensive
disease
– Cosmetics and stains
Benign Skin Conditions: Lentigo
• (see fig. 26-7, Iggy page 465)
– AKA liver spots
– Increased number of melanocytes
– Related to aging and sun exposure
• Manifestations
– Hyperpigmented brown to black flat lesion
– Usually in sun exposed areas
• Treatment
– Liquid nitrogen
• Possible reoccurrence in 1-2 years
– Cosmetics
References:
• Chickenpox in Pregnancy. (2009). March of Dimes Foundation. Retrieved
9/25/09 from http://www.marchofdimes.com/professionals/14332_1185.asp
• Common Poisonous Plants of Florida (Florida Poison Information
Center/Tampa) @ http://www.poisoncentertampa.org/poisonous-plants.aspx
• Culbert, D. (April 14, 2005). Florida scorpions. UF/IFAS Okeechobee County
Extension Service. Retrieved 6/17/09 from
http://okeechobee.ifas.ufl.edu/News%20columns/Florida.Scorpions.htm
• Groch, J. (August 23, 2006). Guidelines for Preventing Pressure Ulcers Seen
as Suboptimal. MedPage Today. Retrieved 6/12/09 from
http://www.medpagetoday.com/Dermatology/GeneralDermatology/3982
References:
• Hembree, D. (July 21, 2008) 10 Poisonous Plants in Florida and
Safety Precautions @
http://www.associatedcontent.com/article/875395/10_poisonous_pla
nts_in_florida_and_pg2.html?cat=11
• “Herpes simplex” (May, 2009). Medline Plus Medical Encyclopedia.
Retrieved 6/15/09 from
http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/001324.htm
• Lilly, L.L., Harrington, S, & Snyder, J. (2005) Pharmacology and the
Nursing Process. (4th ed.) Mosby Elsevier. St. Louis, MS.
• Medical Dictionary (2009) Merrium – Webster Inc. Retrieved 6/15/09
from http://www.nlm.nih.gov/medlineplus/mplusdictionary.html
References:
• The Medical News. Brain eating amoeba in lake kills sixth victim.
(October 2007). Retrieved 6/16/09 from http://www.news-
medical.net/news/2007/10/07/30863.aspx
• The US Market for Skin Care Products. (May, 2005). Retrieved
6/12/09 from http://www.mindbranch.com/Skincare-Products-R567-
0199/
• Scorpion Sting Treatments. (2008). Orkin. Retrieved 6/17/09 from
http://www.orkin.com/other/scorpions/scorpion-sting-treatments
Burns
• Thermal burns
– Flame, flash, scald
• Chemical burns
– Necrotizing substances
• Acids
• Alkali
– Cleaning agents, drain cleaners, lye
• Electrical burns
– Intense heat from electrical current
The
Following
Content –
Burns –
will be
covered in
future
classes!
Save this
information for
future use.
Classification: Depth of Burn
See page 522 in Iggy text
• ABA by depth of destruction
– Partial thickness burn
• Epidermis and dermis involved
– Full thickness burn
• “burns reach through the entire dermis and sometimes into
the subcutaneous fat.” (Iggy, page 522)
• Possibly involves muscles, tendons, and bones
• *Skin cannot heal on its own.
Classification: Extent of Burn
• Total Body Surface Area (TBSF)
– (Iggy page 531)
• Berkow method
– http://www.umobile.edu/main/notes/Burn.pdf
• Rule of 9’s
– (Iggy page 531)
Classification: Location of Burns
• Severity related to location
• Complication risks related to location
• Face, neck, chest
– Respiratory complications
• Hands, feet, joints, and eyes
– Compromise ADLs
• Circumferential burns of extremities
– Circulatory compromise