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MINERALS
BY:-
NITESH KUMAR
B.PHARM VII SEM
JAIPUR COLLEGE OF
PHARMACY, JAIPUR
 DEFINITION :
“A mineral is a chemical element required as an
essential nutrient by organism to perform function
necessary for life”.
OR
“Minerals are inorganic substances required by the
body in small amounts for a variety of different
function”.
 Classification:
1) Major Elements:
-- These are also known as “Macro minerals”.
-- It is required in amount > 100 mg/day.
-- At least 5 gram of the mineral present in the
body.
-- E.g. – Calcium , Sodium , Potassium ,
Chloride ,
2) Minor Elements:
-- These are also known as “Micro minerals”.
-- It is required in amount < 100 mg/day.
-- Less than 5 gram of total mineral present in
the
body.
-- E.g. – Iron , Zinc , Copper , Selenium ,
Chromium ,
Iodide , Manganese , Molybdenum
3) Necessary:
-- It is necessary for the body but their exact
function are not known.
-- E.g. – Chromium , Nickel , Bromide , Lithium ,
Barium
4)Non-Essential:
-- Seen in tissues.
-- Contaminant in food stuffs.
-- E.g. – Rubidium , Silver , Gold ,
Bismuth
5) Toxic:
-- It is should be avoided.
-- E.g. – Aluminum , Cadmium ,
Mercury
 Major minerals:
1. Calcium
Chemical formula : (Ca2+)
Sources : Dairy products , Fish with bones ,
Tofu ,
Leafy green vegetables , legumes ,
Fortified
foods , yogurt , cheese , salmon ,
sardines
Daily Requirement : 1000 mg
Function :
a) Development of bones and teeth
b) Transmission of nerve impulses
c) Blood clotting
d) Normal heart action
Deficiency:
Children – Stunted growth, Adults - Osteoporosis
Toxic effects:
-- Diarrhea
-- Interference with absorption of other
minerals
2. Sodium
Chemical formula : (Na+)
Sources : Table salt . soy sauce , MSG , all
processed
foods
Daily Requirement : 2400 mg
Function:
a) Maintains normal fluid and electrolytes
balance
b) Assists nerve impulse transmission
Deficiency:
-- Muscle cramps , Mental apathy , Loss of
appetite
Toxic effects:
-- Edema , Acute hypertension , Increased
calcium
excretion
3. Potassium
Chemical formula : (K+)
Sources : Fresh vegetables , Bananas , Citrus
food ,
Milk , Meats , Fish
Daily Requirement : 3500 mg
Function:
a) Maintain normal fluid and electrolyte balance
Deficiency:
-- Muscular weakness , Paralysis , Confusion
due to
dehydration
Toxic effects:
-- Muscular weakness , Vomiting reflex
4. Chloride
Chemical formula : (Cl-)
Sources : Table salt , Eggs , Seafood , Milk
Daily Requirement : 3400 mg
Function:
a) Gastric acidity
b) Regulates acid-base balance in the body
c) Maintains fluid & electrolyte balance
d) Formation of hydrochloric acid
Deficiency:
-- Imbalance in gastric acidity
-- Imbalance in blood pH
Toxic effects:
-- Exhaustion
-- Nausea
5. Phosphorous
Chemical formula : (P)
Sources : Fish , Poultry , Eggs , Milk , Meat ,
Cheese ,
Lean , Legumes , Nuts , Whole-Grains
cereals
Daily Requirement : 1000 mg
Function: a) Development of bones & teeth
b) Maintains normal pH of the blood
c) Constituent of all body cells
Deficiency:
-- Weakness , Bone pain
Toxic effects:
-- Low blood calcium , Increased calcium
excretion
6. Magnesium
Chemical formula : (Mg2+)
Sources : Nuts , Legumes , Whole grains ,
Dark
leafy greens , seafood , Chocolate
,Cocoa
Daily Requirement : 350 mg
Function :
a) Mineralization of bones & teeth
b) It helps enzymes function
Deficiency:
-- Weakness , Muscle twitches , Confusion
Convulsion , Bizarre muscle movements
Toxic effects:
-- Confusion , Lack of muscle coordination ,
Death
TRACE ELEMENTS :
1. Iron
Chemical Formula : (Fe+)
Sources : Red meats , Fish , Poultry , Eggs ,
Legumes ,
Dried fruits , Shellfish , Liver , Whole
grains
or enriched breads & cereals , Dark
Diet requirements : 15 mg
Functions
a) Transports oxygen & carbon dioxide
b) Hemoglobin formation
c) Component of cellular enzymes essential for
energy production
Deficiency:
-- Anaemia , Weakness , Headaches ,
Reduced
immunity , low cold tolerance
Toxic effects:
-- Infection , Fatigue , Liver damage ,
Colon
cancer , Bloody stools , Fatal to kids
2. Zinc
Chemical Formula : (Zn+)
Sources : Seafood , Eggs , Milk , Legumes ,
Wheat bran ,
Esp. oysters
Daily Requirements : 15 mg
Functions
a) Formation of collagen
b) Wound healing
c) Taste acuity
d) Essential for growth
e) Immune reaction
Deficiency:
-- Failure to grow , Dermatitis , Loss of taste ,
Poor healing , Sex retardation
Toxic effects
-- Nausea , Fever , Vomiting , Dizziness ,
Uncoordinated , Anaemia , Heart disease
3. Copper
Chemical Formula : (Cu)
Sources : Poultry , Shellfish , Legumes , Whole grain
breads , Cereals
Diet requirement : 2 mg
Functions
a) Facilitates the function of many enzymes
b) Iron may be an integral part of DNA & RNA
molecule
Deficiency
-- Pallor , Retarted growth , Edema , Anorexia
Toxic effects :
--Wilson’s disease, Deterioration of neurological
4. Selenium
Chemical Formula : (Se+6)
Sources : Seafood , Meats , Grains , Vegetable
depending on soil content , Whole
grains ,
Cereals
Diet requirement : 35 μg
Functions :
a) Antioxidants
b) Works with Vitamin E
Deficiency : - Keshan disease , Muscle pain /
degradation , Cataracts , Low sperm
,
Fragile RBCs , Heart damage.
Toxic effects : Muscle damage , Nail & Hair
5. Chromium
Chemical Formula : (Cr)
Sources : Meat , Whole grains , Vegetable oils
Diet requirement : 120 μg
Functions
-- It helps insulin move glucose from
blood
into cells
Deficiency
-- Abnormal glucose metabolism
Toxic effects
-- Possible muscle degeneration
6. Iodine
Chemical formula – I
Source - Iodized salt, seafood and plant grown
in
rich iodine soil
Diet requirement - 150
Functions –
a.) A component of thyroid hormone – helps
to
regulate growth, development,
metabolism.
b.) Regulation of basal metabolic rate.
Deficiency
-- Goiter, Cretinism, Myxedema
Toxic effects
-- Low thyroid activity
-- Enlarged thyroid
g

7. Manganese
Chemical Formula : (MnO2)
Sources : Whole grains , Nuts , Fruits ,
Vegetable
Diet requirement : 5 mg
Functions : Enzyme function
Deficiency :
-- Impaired growth , Skeletal
abnormalities , Neonatal ataxia
Toxic effects:
a) In extremely high exposure from
contamination
b) Severe psychiatric & neurologic
disorder
8. Molybdenum
Chemical Formula : (Mo+2)
Sources : Whole grains , Organ meat , Peas ,
Beans
Diet requirement : 75 μg
Functions : Energy metabolism
Deficiency
a) Brain abnormalities
b) Developmental delays
c) Childhood death
d) It’s extremely rare
Toxic effects : Gout like syndrome
9. Fluoride
Chemical Formula : (F-)
Sources : Fluoridated water , Seafood , Tea
Diet requirement : 3-5 mg
Functions:
a) Helps to make bones & teeth stronger
b) Increase resistance to tooth decay
Deficiency:
a) Susceptibility to tooth decay
b) Possibly osteoporosis
Toxic effects:
a) Chest pain
b) Fluorosis
c) Discolored teeth
d) Nausea
Minerals
Minerals
Minerals

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Minerals

  • 1. MINERALS BY:- NITESH KUMAR B.PHARM VII SEM JAIPUR COLLEGE OF PHARMACY, JAIPUR
  • 2.  DEFINITION : “A mineral is a chemical element required as an essential nutrient by organism to perform function necessary for life”. OR “Minerals are inorganic substances required by the body in small amounts for a variety of different function”.  Classification: 1) Major Elements: -- These are also known as “Macro minerals”. -- It is required in amount > 100 mg/day. -- At least 5 gram of the mineral present in the body. -- E.g. – Calcium , Sodium , Potassium , Chloride ,
  • 3. 2) Minor Elements: -- These are also known as “Micro minerals”. -- It is required in amount < 100 mg/day. -- Less than 5 gram of total mineral present in the body. -- E.g. – Iron , Zinc , Copper , Selenium , Chromium , Iodide , Manganese , Molybdenum 3) Necessary: -- It is necessary for the body but their exact function are not known. -- E.g. – Chromium , Nickel , Bromide , Lithium , Barium
  • 4. 4)Non-Essential: -- Seen in tissues. -- Contaminant in food stuffs. -- E.g. – Rubidium , Silver , Gold , Bismuth 5) Toxic: -- It is should be avoided. -- E.g. – Aluminum , Cadmium , Mercury
  • 5.  Major minerals: 1. Calcium Chemical formula : (Ca2+) Sources : Dairy products , Fish with bones , Tofu , Leafy green vegetables , legumes , Fortified foods , yogurt , cheese , salmon , sardines Daily Requirement : 1000 mg Function : a) Development of bones and teeth b) Transmission of nerve impulses c) Blood clotting d) Normal heart action
  • 6. Deficiency: Children – Stunted growth, Adults - Osteoporosis Toxic effects: -- Diarrhea -- Interference with absorption of other minerals 2. Sodium Chemical formula : (Na+) Sources : Table salt . soy sauce , MSG , all processed foods Daily Requirement : 2400 mg Function: a) Maintains normal fluid and electrolytes balance b) Assists nerve impulse transmission
  • 7. Deficiency: -- Muscle cramps , Mental apathy , Loss of appetite Toxic effects: -- Edema , Acute hypertension , Increased calcium excretion 3. Potassium Chemical formula : (K+) Sources : Fresh vegetables , Bananas , Citrus food , Milk , Meats , Fish Daily Requirement : 3500 mg Function: a) Maintain normal fluid and electrolyte balance
  • 8. Deficiency: -- Muscular weakness , Paralysis , Confusion due to dehydration Toxic effects: -- Muscular weakness , Vomiting reflex 4. Chloride Chemical formula : (Cl-) Sources : Table salt , Eggs , Seafood , Milk Daily Requirement : 3400 mg Function: a) Gastric acidity b) Regulates acid-base balance in the body c) Maintains fluid & electrolyte balance d) Formation of hydrochloric acid
  • 9. Deficiency: -- Imbalance in gastric acidity -- Imbalance in blood pH Toxic effects: -- Exhaustion -- Nausea 5. Phosphorous Chemical formula : (P) Sources : Fish , Poultry , Eggs , Milk , Meat , Cheese , Lean , Legumes , Nuts , Whole-Grains cereals Daily Requirement : 1000 mg Function: a) Development of bones & teeth b) Maintains normal pH of the blood c) Constituent of all body cells
  • 10. Deficiency: -- Weakness , Bone pain Toxic effects: -- Low blood calcium , Increased calcium excretion 6. Magnesium Chemical formula : (Mg2+) Sources : Nuts , Legumes , Whole grains , Dark leafy greens , seafood , Chocolate ,Cocoa Daily Requirement : 350 mg Function : a) Mineralization of bones & teeth b) It helps enzymes function
  • 11. Deficiency: -- Weakness , Muscle twitches , Confusion Convulsion , Bizarre muscle movements Toxic effects: -- Confusion , Lack of muscle coordination , Death TRACE ELEMENTS : 1. Iron Chemical Formula : (Fe+) Sources : Red meats , Fish , Poultry , Eggs , Legumes , Dried fruits , Shellfish , Liver , Whole grains or enriched breads & cereals , Dark
  • 12. Diet requirements : 15 mg Functions a) Transports oxygen & carbon dioxide b) Hemoglobin formation c) Component of cellular enzymes essential for energy production Deficiency: -- Anaemia , Weakness , Headaches , Reduced immunity , low cold tolerance Toxic effects: -- Infection , Fatigue , Liver damage , Colon cancer , Bloody stools , Fatal to kids
  • 13. 2. Zinc Chemical Formula : (Zn+) Sources : Seafood , Eggs , Milk , Legumes , Wheat bran , Esp. oysters Daily Requirements : 15 mg Functions a) Formation of collagen b) Wound healing c) Taste acuity d) Essential for growth e) Immune reaction Deficiency: -- Failure to grow , Dermatitis , Loss of taste , Poor healing , Sex retardation
  • 14. Toxic effects -- Nausea , Fever , Vomiting , Dizziness , Uncoordinated , Anaemia , Heart disease 3. Copper Chemical Formula : (Cu) Sources : Poultry , Shellfish , Legumes , Whole grain breads , Cereals Diet requirement : 2 mg Functions a) Facilitates the function of many enzymes b) Iron may be an integral part of DNA & RNA molecule Deficiency -- Pallor , Retarted growth , Edema , Anorexia Toxic effects : --Wilson’s disease, Deterioration of neurological
  • 15. 4. Selenium Chemical Formula : (Se+6) Sources : Seafood , Meats , Grains , Vegetable depending on soil content , Whole grains , Cereals Diet requirement : 35 μg Functions : a) Antioxidants b) Works with Vitamin E Deficiency : - Keshan disease , Muscle pain / degradation , Cataracts , Low sperm , Fragile RBCs , Heart damage. Toxic effects : Muscle damage , Nail & Hair
  • 16. 5. Chromium Chemical Formula : (Cr) Sources : Meat , Whole grains , Vegetable oils Diet requirement : 120 μg Functions -- It helps insulin move glucose from blood into cells Deficiency -- Abnormal glucose metabolism Toxic effects -- Possible muscle degeneration
  • 17. 6. Iodine Chemical formula – I Source - Iodized salt, seafood and plant grown in rich iodine soil Diet requirement - 150 Functions – a.) A component of thyroid hormone – helps to regulate growth, development, metabolism. b.) Regulation of basal metabolic rate. Deficiency -- Goiter, Cretinism, Myxedema Toxic effects -- Low thyroid activity -- Enlarged thyroid g 
  • 18. 7. Manganese Chemical Formula : (MnO2) Sources : Whole grains , Nuts , Fruits , Vegetable Diet requirement : 5 mg Functions : Enzyme function Deficiency : -- Impaired growth , Skeletal abnormalities , Neonatal ataxia Toxic effects: a) In extremely high exposure from contamination b) Severe psychiatric & neurologic disorder
  • 19. 8. Molybdenum Chemical Formula : (Mo+2) Sources : Whole grains , Organ meat , Peas , Beans Diet requirement : 75 μg Functions : Energy metabolism Deficiency a) Brain abnormalities b) Developmental delays c) Childhood death d) It’s extremely rare Toxic effects : Gout like syndrome
  • 20. 9. Fluoride Chemical Formula : (F-) Sources : Fluoridated water , Seafood , Tea Diet requirement : 3-5 mg Functions: a) Helps to make bones & teeth stronger b) Increase resistance to tooth decay Deficiency: a) Susceptibility to tooth decay b) Possibly osteoporosis Toxic effects: a) Chest pain b) Fluorosis c) Discolored teeth d) Nausea