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Nk mmc ventilation basics 2017
1. BASICS OF MECHANICAL VENTILATION
PROF N.KRISHNAN
Dept of Paediatric Anaesthesiology
Institute of Child Health & Hospital for Children- Chennai
Madras Medical College
2. OBJECTIVES
TO KNOW THE
BASIC PHYSICS
TERMINOLOGIES BEING USED
PHYSIOLOGY DURING MECHANICAL VENTILATION
PHASES OF RESPIRATION IN MECHANICAL VENTILATION
3. Major indications for mechanical ventilation
LOW Pao2 cannot be maintained above 50mm hg despite high levels of
delivered oxygen.
(Ards).
HIGH PACO2 In arterial blood rises above 50 torr.
Acute respiratory failure (arf).
Ventilation becomes inefficient and/or exhausted.
Bronchospasm, flail chest and impending respiratory failure.
Airway protection
Tracheal injury, edema, severe head injury and facial fractures.
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7. NORMAL INSPIRATION
An active process requiring musular
effort.
75% diaphragmatic at rest.
Intercostals used during exertion.
8.
9. Inspiratory effort causes
• Fall in intrapleural pressure
• Fall in Alveolar pressure
• “Pressure gradient from
mouth to alveoli ”
• Gas flow down pressure
gradient
11. Normal Expiration
Relaxation of
inspiratory muscles
causes:
Intrapleural pressure
becomes less negative
Alveolar pressure rises
“Pressure gradient
from alveoli to mouth”
Gas flow down
pressure gradient
12. Positive pressure ventilation
Positive pressure applied to the
airway during inspiration to
expand the lungs and chest wall
to get Tidal Volume .
Spontaneous ventilation
14. Volume
A volume can be defined as
Measuring the amount of space occupied by an object.
The SI unit of a volume is cubic metre [m3 ]
smaller SI unit of volume is cubic centimeter [cm3. ]
18. FLOW
FLOW
The motion of a gas or
liquid
FLOW RATE
• Flow Rate is defined as the
volume of gas or liquid
passing a cross sectional
area per unit of time.
19. FLOW RATE
• Flow is defined as the volume of gas or liquid passing a cross sectional
area per unit of time.
Flow = volume / time
22. Ti (Inspiratory Time):
Time over which the tidal
volume is delivered
Setting:
0.1 to 5.00 sec
Maintain an I:E of 1:2 or
greater (1:3, 1:4, etc.)
23. T pause
Time for no flow or pressure
delivery (%)
Setting: 0.00 to 1.50 sec
24. Inspiratory Rise Time
or
“T insp. Rise”
The time taken to reach the
peak inspiratory flow or
pressure at the start of each
breath.
25. Inspiratory Rise Time
or
“T insp. Rise”
Inspiratory Rise Time, set in seconds
Setting: 0 to 0.40
Adults range is 0 to 0.40 seconds
Infants range is 0 to 0.20 seconds
29. Abnormal Increase In Lung resistance
A . Airway lumen occluded by foreign
material
B. Edema or hypertrophy of the airway
wall
C. Spasm
D. Collapse of the airway
Croup
Epiglotitits
Anaphylactic reactions
Asthma
Bronchitis
Bronchiectasis
Cystic fibrosis
Vocal cord problems
Goiters
Thyroid tumors
30. Compliance
The ease in which a structure
can be expanded or stretched
Change in volume/change in
pressure
cc or ml/cm H20
Both the lung and thorax involved.
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31. Abnormal Decrease In Lung Compliance
Abdominal Factors
1. obesity
2. abdominal surgery
3. Pregnancy
Pleural Factors
1. Pneumothorax
2. Pleural Effusion
Pulmonary Factors
1. Atelectasis
2. ARDS and IRDS
3. pulmonary edema (fluid in alveoli)
4. Thoracic surgery
5. pulmonary fibrosis (increased elasticity)
6. pneumonia (fluid filled alveoli)
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32. Elastance
• THE RECIPROCAL OF
COMPLIANCE
• The quality of recoiling to an original
form after the removal of pressure.
• The degree to which LUNG, can return
to its original dimensions when a
distending PRESSURE is removed.
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34. POSITIVE PRESSURE
CFG CPG
EXPANSION OF LUNG
NORMAL
INSPIRATION
OVERDISTENTION:
VOLUTRAUMA
RUPTURE :
BAROTRAUMA
PHYSIOLOGY OF POSITIVE PRESSURE VENTILATION
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35. Physiological changes to PPV
Cardiovascular effects
The heart, great vessels, and
pulmonary vasculature lie
within the chest cavity in
which the pressure is
normally negative.
During PPV they are all
subjected to the increased
intra thoracic pressure.
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36. Cardiovascular effects
Decreased venous return to
the right heart .
Altered left ventricular
distensibility
The result is a decrease in
cardiac output
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37. Renal, Hepatic, and Gastrointestinal Effects
Decline In Renal Function :
Decreased urine volume and sodium excretion.
Decline In Hepatic Function :
Due to decrease in cardiac output.
Increased hepatic vascular resistance.
The Gastric Mucosal Ischemia And Secondary Bleeding :
Result from a decrease in cardiac output .
Increased gastric venous pressure
CNS :
Raised intra cranial pressure
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38. How will you give minute ventilation to your patient
?????
39. Select - For your patient
Type of ventilator
Mode of ventilation
Give Orders to be followed during Phases of respiration
41. Constant flow generator
[Volume Ventilator]
Flow generators are ventilators which produces constant inspiratory flow.
A high-pressure gradient is established between the ventilator and the
patient.
The result is a Constant Flow Pattern .
Does not care about lung characters ,
Will deliver set tidal volume.
Dictator
42. Constant- Pressure Generator
Pressure generators are ventilators which produces variable inspiratory
flow.
The machine develops a constant pressure that is only slightly above the
pressure in the patient's airways.
Flow varies with resistance & compliance of lung
DEMOCRACY
45. Power source
Compressed gas or electricity
Is the force that drives gas into the patient's lungs.
Bellows Ventilators use the force of compressed
gases, separated from patient gas by a membrane
(bellows).
Electricity to drive a piston or turbine containing
patient gas.
All use electricity for electronic sensors and
computer control mechanisms.
46. GENERATORS - CFG /CPG
To get tidal volume gas should flow to the alveoli from ventilator
47. Constant flow generator
[Volume Ventilator]
Flow generators are ventilators which produces constant inspiratory flow.
A high-pressure gradient is established between the ventilator and the
patient.
The result is a Constant Flow Pattern .
Does not care about lung characters ,
Will deliver set tidal volume.
Dictator
48. Drive mechanism
Generates inspiratory flow
Piston ventilators (Apollo, Fabius
GS) do not require driving gas.
They are driven by compression
from an electric motor to move a
piston, creating pressure which
moves the gas within the piston to
the patient's lungs.
Thus, piston or turbine ventilators are
economical of wall oxygen .
49. Drive mechanism
Generates inspiratory flow
Turbine ventilators (Dräger Perseus)-
electric motor used to drive a turbine
(blower) which creates inspiratory
pressure and flow.
(Hair Dryer)
50. Drive mechanism -
Generates inspiratory flow
Bellows vents classified as
double-circuit, pneumatically
driven.
Double-circuit means that a
pneumatic force (driving gas)
compresses a bellows, which
empties its contents (patient gas
into the patient].
Driving gas is oxygen or air.
56. Phases of respiration
Inspiration
Inspiration-Expiration change over
Expiration
Expiration- Inspiration change over
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57. Give orders for each Phases of respiration
Inspiration
Inspiration-Expiration change over
Expiration
Expiration- Inspiration change over
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62. Trigger Variable- Pressure
Pressure - Patient
Assisted
A sensor SENSES A
DECREASE IN PRESS
IN INSPIRATORY
CIRCUIT & initiates
inspiration
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63. Trigger
Variable- Flow
Expiratory flow starts to decrease at
the end of expiration.
A flow sensor detects the
decrease in flow.
When expiratory flow starts to
decrease to around
1-3 lit / min triggering will occur.
Ventilator initiates inspiration.
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66. HIGH SENSITIVITY [-0.5] = Little effort needed from
patients.
Early phase of recovery
AUTOCYCLING with HIGH SENSITIVITY during later
stages of recovery.
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75. Volume Control
Tidal volume is
preset.
Rate delivered is
preset.
Pressure is
variable throughout
the delivered breath
Flow is constant
throughout the breath
76. Volume Control — vent settings
1.Tidal Volume (ml)
2. Respiratory Rate (b/min)
3. PEEP (cmH2O)
4. Oxygen concentration (%)
5. I:E ratio / Insp. time
6. Pause time (s)
7. Inspiratory rise time (s)
8. Trigg. Flow / Trigg. Pressure
77. Volume Control
Terminates inspiration at
preset volume
Delivers volume at whatever
pressure is required up to
specified peak pressure
May produce dangerously High
Intrathoracic Pressures
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80. Pressure Control
A pressure level is preset.
Breaths are delivered at a preset
rate.
Tidal and minute volume are
variable.
Flow is variable throughout the
breath
81. Pressure Control
A pressure level is preset.
Breaths are delivered at a preset rate.
Pressure is constant throughout the
delivered breath.
Tidal and minute volume are variable.
Flow is variable throughout the breath
82. Pressure Control — vent settings:
PC (Pressure Control level)
above PEEP (cmH2O)
Respiratory Rate (b/min)
PEEP (cmH2O)
Oxygen concentration (%)
83. Pressure Control — vent settings:
I:E ratio / Insp. Time
Inspiratory rise time (s)
84. Pressure Control — vent
settings
The set inspiratory
pressure level for each
mandatory breath
Setting:
Infant range is 0 to 80 cmH2O.
Adult range is 0 to 120 cmH2O
85. Pressure Cycled
Terminates inspiration at preset
pressure
Tidal volume may vary with
changes in airway resistance,
pulmonary compliance
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87. Other names for Pressure
Control:
P-CMV
PCV-A/C
Pressure
A/C
88. Time cycled
ventilation
Time interval fixed. [6 sec /
breath]
Resp rate fixed. [10/ min ]
Adjust I:E ratio, Ti
[ TV = FLOW X TIME ]
Adjust flow rate to achieve
tidal volume
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89. Time cycled
– Terminates inspiration at preset
time
– Volume determined by
• Length of inspiratory time
• Pressure limit set
• Patient airway resistance
• Patient lung compliance
– Common in neonatal units
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90. FLOW cycled ventilation
Expiration begins when
inspiratory flow rate decays to
predetermined percentage of its
peak flow.
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93. Positive End Expiratory Pressure
(PEEP) refers to positive
pressure maintained throughout
and at the end of exhalation.
maintaining airway and alveolar
integrity for air flow and gas
exchange.
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96. Controlled modes
Mandatory breath modes
Every breath delivered to patient by a mechanical breath.
(Breath may be triggered by a timing mechanism or patient
effort).
Volume Control
Pressure Control
PRVC
97. Supported (spontaneous) modes
Every breath is spontaneous (i.e., patient triggered and
patient cycled) but supported by ventilator.
Pressure support / CPAP
Volume support
NAVA- Neurally Adjusted Ventilatory Assist
98. Combination modes
Combination of both controlled and supported
SIMV (VC) + PS
SIMV (PC) + PS
SIMV (PRVC) + PS
Bi-vent
101. Ve Minute volume
Spon Ve Minute volume, spontaneous
Rate Breath rate, total
Spon rate Rate, spontaneous
Mand rate Rate, mandatory
Ti Time, inspiratory
Te Time, expiratory
I:E Ratio, Ti/Te
f/Vt Rapid shallow breathing index
102. Ppeak Peak inspiratory
pressure
Pmean Mean airway
pressure
Pplat Plateau pressure
PEEP Positive end
expiratory pressure
Air inlet Pressure, air supply
O2 inlet Pressure, oxygen
supply
FiO2 Percent oxygen
content delivered
104. Alarms
Loss of O2 Oxygen supply lost
Loss of airAir supply lost
Low battery Internal/external batteries low
Loss of A/C Main AC power lost
Low PEEP Low PEEP cmH2O
Low Ppeak Low PIP cmH2O
Low Vte Low tidal volume
Low Ve Low minute volume
Low %O2 Low FiO2 reading
High %O2 High FiO2 reading
105. Alarms
High Ve High minute volume
High rate High breath rate
Max insp time Inspiratory time limit exceeded
I:E limit I:E ratio limit exceeded
High Vt High tidal volume
Vol limit Volume limit exceeded
Low EtCO2 Low end tidal CO2
High EtCO2 High end tidal CO2
109. The Proximal Airway Pressure (Paw)
The Proximal Airway Pressure (Paw) is the
PRESSURE AT THE WYE PIECE which
creates pressure difference with alveoli
for the gas to move from machine to
patient during inspiration
111. Peak inspiratory pressure (PIP)
Peak inspiratory pressure (PIP) is the
pressure measured in the ventilator
circuit DURING MAXIMAL GAS
FLOW .
It primarily represents the interaction
between the inspiratory flow rate and
airway resistance.
112. Peak inspiratory pressure (PIP)
Pressure required to move air through
airways and into alveoli.
PIP is the measurement of maximum
driving pressure required to expand
the lungs and chest wall to a given
volume.
113. Peak Inspiratory Pressure
total pressure needed to overcome
1.The inspiratory flow resistance
(resistive pressure),
2.The elastic recoil of the lung and chest wall .
(elastic pressure),
3.The alveolar pressure present at the beginning of the
breath
[PEEP]
115. Peak Inspiratory
Pressure (PIP)
(PIP) is expressed in centimeters
of water pressure (cmH2O).
PIP should be monitored to
reduce the risk of
BAROTRAUMA.
119. MAP
Too low a MAP may result in
hypoventilation and
atelectasis.
Too high a Paw can
increase the risk of
barotrauma.
significantly compromise
hemodynamics.
120. Mean airway pressure
is a function of the
Inspiratory and expiratory
time
Peak inspiratory pressure
PEEP
Bias flow.
121. Ways to increase mean airway pressure
1.Increase inspiratory flow rate
2. Increase peak inspiratory
pressure
3. Increase inspiratory time
4. Increase PEEP
5. Reduce expiratory time
123. The plateau
pressure
Pstat is generally considered to be the
PRESSURE DISTENDING THE
ALVEOLI,
control of the plateau pressure is
important, as excessive stretch of
alveoli has been implicated as the
cause of ventilator induced lung
injury.
125. Static" Compliance
Static" Compliance “ is a
measure of the "stiffness" of
lung and chest wall.
Measured during inspiratory
hold and no flow of air.
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126. Measurement of the plateau pressure
End-inspiratory hold
maneuver which allows
equilibration of pressure
between the mouth and alveoli.
To determine the relative
contributions of resistive and
elastic pressures.
The maneuver keeps the
exhalation valve closed for an
additional 0.3 to 0.5 sec after
inspiration, delaying
exhalation.
During this time, peak airway
pressure falls from its peak
value as airflow ceases.
127. Static" Compliance
NORMAL FOR THORAX -200
CC/CM H20
NORMAL FOR LUNG -200
CC/CM H20
NORMAL FOR LUNG +
THORAX- 100 cc/cm H20
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Cstat = Vt /(Pp1 – PEEP)
Vt = tidal volume
Ppl = plateau pressure
128. Static" Compliance
When the static compliance
decreases to approximately 25
mL/cm H2O, the work of breathing
will appreciably increase.
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129.
130.
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LINEAR COMPLIANCE AREA
Ventilation should take place as far as
possible within the LINEAR
COMPLIANCE AREA (B), as dangerous
shear forces occur as a result of the
collaborating and reopening of
individual areas of the lung.
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LINEAR COMPLIANCE AREA
The lower inflection point can be overcome by
setting a PEEP.
Ventilation volume & Inspiratory pressures must
then be selected such that the UPPER
INFLECTION POINT WILL NOT BE EXCEEDED.
134. The plateau
pressure
Control of the plateau pressure is
important, as excessive stretch of
alveoli has been implicated as the
cause of ventilator induced lung
injury.
136. Peak Inspiratory and Plateau Pressures
• 1. Peak Inspiratory Pressure (PIP)
• This pressure A FUNCTION OF THE COMPLIANCE OF THE LUNG
AND THORAX AND THE AIRWAY RESISTANCE
• 2. Plateau Pressure
• THE PLATEAU PRESSURE REFLECTS LUNG AND CHEST
WALL COMPLIANCE.
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137. An Increase In Airways Resistance will result in
1. An increase in pip.
2. A widening of the difference between pip and plateau
pressure.
138. • A fall in compliance will
1. Elevate both PIP and plateau pressure
139. Auto-PEEP
When the expiratory time is
not sufficient for the lungs to
empty before delivery of the
next breath (Air Trapping),
then the alveolar pressure
will be greater than the
baseline at end-expiration
even though PEEP has not
been set on the ventilator
Auto PEEP
CHECK FLOW
PEEP
CHECK FLOW
140. Auto-PEEP
• Auto-PEEP may occur because
Expiratory times are too short .
Respiratory rates are too high.
Because of intrinsic lung disease.
• Drug therapy, or the adjustment of rate or expiratory time, may eliminate this
condition
141. Auto-PEEP
IF PRESSURE continues to build
in this manner, delivered tidal
volumes will drop, work of
breathing will increase .
Patients with obstructive lung
disease are prone to the
development of auto-PEEP.
142. Detection of auto-PEEP
• To detect auto-PEEP, an
expiratory hold is performed
and the pressure measured.
• If the pressure during the
expiratory hold is greater than
the set PEEP, auto-PEEP is
present.
• To correct auto-PEEP reduce
airway obstruction or increase
expiratory time.
144. Tidal Volume Vt
The amount of air which enters the lungs during inhalation .
145. The achieved tidal volume
depend to an equal extent
on the
1. Properties and settings of
the ventilator.
2. The respiratory properties
of the lung
146. Tidal Volume
• TV is only set in volume-controlled modes of
ventilation and is usually 8-12cc/kg of body weight.
• The tidal volume is closely related to ventilation.
The tidal volume is often manipulated to abnormal
levels of CO2.
147. Tidal Volume- types
• Mechanical Tidal Volume
represents the volume delivered
by a mechanical ventilator.
• Spontaneous Tidal Volume
depicts the amount of gas
exchanged by the patient’s own
efforts.
148. Exhaled tidal volume - EVT
Leak in circuit.
Around the ETT.
Pleural leak.
Compression of circuit.
Normal Difference of 50 ml between VT &
EVT
149. Rate
• The set ventilatory rate is the minimum number of breaths
delivered to the patient per minute.
• The actual rate may be higher than the set rate if the patient is
initiating spontaneous breaths.
• Rate is adjusted in response to the patient’s CO2 levels.
150. Minute Ventilation
• Minute ventilation is the rate
multiplied by the tidal volume.
• Total Minute Ventilation (V) is all
mechanical and spontaneous tidal
volumes for a period of one
minute, stated in liters (L).
152. Inspiratory
Time
Inspiratory Time is
the time over which
the tidal volume is
delivered .
Expiratory time is
whatever time is left
over before the next
breath
155. FLOW RATE
• Flow is defined as the volume of gas or liquid passing a cross sectional
area per unit of time.
Flow = volume / time
156. Flow Waveforms
• A deflection above the baseline of
the flow waveform indicates gas is
flowing into the patient
(INSPIRATION).
• A deflection below baseline of the
flow waveform indicates that gas is
flowing out of the patient
(expiration).
160. DECELERATING RAMP
Peak flow at start.
Gradually decelerates.
Flow ceases when flow decays to a set %
of peak flow.
Raises MAP = more recruitment of alveoli.
Reduces PIP.
Improve distribution
162. Bias Flow – the basal flow rate
Bias Flow – the basal flow rate
ALWAYS flowing through the
vent.
circuit to assist with patient
triggering.
Normal 0-40 lpm
Ensures MAP and that CO2 doesn't
accumulate in the inspiratory limb
upon patient exhalation.
A lower bias flow is the reason PS
must be used. That way patients
can more easily inhale and
overcome the negative pressure of
the vent. circuit.
165. Thanks to all sources in
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Meant only for sharing of knowledge
Editor's Notes
Maximum inspiratory force if < 20 cmH2O most patients have difficulty
Maximum inspiratory force if < 20 cmH2O most patients have difficulty Maximum inspiratory force : used as an index of resp. effort.
if < 20 cmH2O most patients have difficulty
Pressure (symbol: p or P)
The force applied perpendicular to the surface of an object per unit area
inspiratory pause time is only set in modes where a fixed tidal volume is set and delivered (volume control and volume preset SIMV modes)
expiratory time is whatever time is left over before the next breath
Inspiratory Rise Time (%) is applicable in Pressure Control, Volume Control, PRVC, SIMV-Volume Control, SIMV-Pressure Control, SIMV-PRVC.
The measurement of the unit volume of change in such an organ PER UNIT OF DECREASED PRESSURE CHANGE.
Mean airway pressure is the area under the pressure-time curve divided by the time required FOR A COMPLETE RESPIRATORY CYCLE.
Measured by the inspiratory hold which allows equilibration of pressure between the mouth and alveoli.
In pressure-controlled modes of ventilation the tidal volume is not set.
inspiratory pause time is only set in modes where a fixed tidal volume is set and delivered (volume control and volume preset SIMV modes)
expiratory time is whatever time is left over before the next breath