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Dr. Amit Gupta
Dr. Clare Groves
Radiology Department
Bradford Royal Infirmary
 Bit of a Cinderella topic
 Needs a ‘Champion’ in every Trust to show the
world how interesting and important it is
 Effective fracture prevention need the whole
radiology team to ‘buy in’.
 Osteoporotic fractures are VERY
common
 30% of post-menopausal women
 Estimated lifetime risk of
fracture at hip, lumbar spine or
distal forearm is 30-40% in
developed countries
 Hip fractures are associated with
significant increase in morbidity
and mortality.
Hip FX
Vertebral Fx
Fragility Fx
Probability of
osteoporosis
in over 50’s
Very high
High
Moderate
Hip FX
Vertebral Fx
Fragility Fx
Probability of
osteoporosis
Very high
High
Moderate
FLS/FRAX
Hip Fractures
are preventable
Intervene
Here
 Detecting and treating vertebral fractures early
can:
1. Prevent new vertebral fractures
2. Prevent significant patient morbidity
3. Prevent hip fractures in the future
4. Save money for the NHS
 Current annual UK estimate of hip fractures –
60,000
 Increasing 1-3% per year
 Hospital costs for a hip fracture £3459 — £33,264
(mean of £12,163)
Total annual financial burden
£730 million*
* T M Lawrence, C T White, R Wenn et al. The current hospital cost of treating hip
fractures. Injury, Int. J. Care Injured (2005) 36, 88-91
 As health professionals, we are in an ideal
position to identify and respond to both
suspected and incidental findings of vertebral
fractures.
 2/3 of vertebral fractures don’t come to clinical
attention -‘silent fractures’
 Be aware of ‘at risk’ patients
 Be aware of history of FFx
 Be aware of signs – dowger’s hump
 Studies have shown a global 34% false
negative rate in analysis of spinal radiographs
by radiologists
 For general CT, detection rates for spinal
fracture have been reported at between 9-16%
 Even when vertebral fracture is identified, only
one-quarter of patients are started on
treatment.
Sagittal reconstruction spine
• CT Abdomen performed for
abdominal pain
• Spinal reconstruction not
made at the time
• Multiple vertebral fractures
unreported
• Two years later patient
sustained a hip fracture
• We might have prevented
that hip fracture !
 Recommendations for plain film reporting vertebral
fractures from the IOF:
 Scrutinise all images for such fractures
 Use clear, unambiguous and accurate terminology –
the word ‘fracture’ not ‘collapse’ or other terms
 Give number and grades of fractures: mild=1,
moderate=2, severe=3.
 Indicate if osteoporotic, traumatic or pathological
and suggest further appropriate imaging, if relevant.
 If osteoporotic in origin, suggested measures should
be considered to reduce fracture risk.
 Four years ago, no Fracture Liaison Service
 Falls and Fragility fracture CQUIN
 CJG decided that imaging could be a driver for
change.
 AUDIT to establish the the current state of
play.
 Plain film spine reports with regards to:
 Fractures being identified
 Use of the word ‘Fracture’ in reports
 Grading of fracture
 Description of fracture morphology
 Recommendation for further assessment of
osteoporosis.
16
Criterion Standar
d
Results
Fracture
Identified
100% 97/103 = 94.2%
Term “fracture”
used if identified
100% 80/97 = 82.5%
Grade given 100% 67/103 = 65%
Correct
Descriptor used
100% 84/103 = 81.6%
Dexa recommended if
no previous evidence
of osteoporosis
100% 18/82 = 22%
 Vertebral fracture identification rate at BRI was
reasonable on plain film
 Terminology used i.e. the word ‘fracture’ - did
not meet expected standards
 Grading and description of vertebral fractures
did not meet expected standards
 As recognised globally, a sufficient number of
reports in which fracture is identified did not
carry a recommendation regarding further
action/assessment.
 Reporters of spinal films (consultants, trainees,
radiographers) should be aware of the requirement to
use the word ‘fracture’ and to number, grade and
describe their morphology.
 Identification of a fracture should lead to a
recommendation for assessment of osteoporosis if no
prior evidence for this exists.
 Terminology used in reports that is helpful;
“Osteoporosis should be considered”, “Has
osteoporosis been excluded?” “I suspect this may be
osteoporotic”.
 The International Osteoporosis Foundation
provide an online vertebral fracture teaching
program for radiologists;
http://www.iofbonehealth.org/vertebral-
fracture-teaching-program
 First Audit (plain film) was a consciousness-
raising exercise.
 Second Audit (CT) performed 12 months later
 To assess the detection rate and quality of
radiological reporting of spinal fractures in CT
in accordance to Genant & Wu gold standard
 To encourage use of standardised language in
reports according to Genant & Wu
classification.
 Female patient aged over 45
 167 consecutive CT examinations were
reviewed retrospectively including
• CTPA
• CT thorax and CT abdomen/Pelvis
 4 examinations were excluded as no thin slices
were available on PACS to construct sagittal
reformat.
 163 studies reviewed
• 37/163 patients had one or more vertebral fractures
(prevalence 22.7%)
37 fracture
Present
5 correctly identified
(13.5%)
all 5 had used word
'fracture'
2 cases Grades given
2 cases Correct
discriptors used
3 No grades and
incorrect descriptor
used
32 not identified
(86.5%)
13.5% pick-up rate (in 103 positive cases)
25% had DEXA recommended
Plan of Action
Introduction of an automated
short code
Area for improvement
The term fracture should be
used whenever a vertebral
fracture is identified
Vertebral Fractures should be
graded and categorized
Recommendation for DEXA
assessment should be included
in the report if there is no
previous evidence of
osteoporosis
 Vertebral fracture detection rate at BRI was
comparable to published figures, but very poor
 NOT utilising the available 3D reconstruction
software.
 Routine provision of sagittal spinal
reconstructions for all general CT studies.
 Encouraging radiologists to refer directly for
DEXA after finding spinal fractures in patients
over 50y using a short code
 Consciousness raising again – presentations,
flyers, general nagging etc etc.
 This has also been audited AND presented at
clinical governance
……consciousness-raising
 81 direct access DEXA referrals from radiology
between January and July 2014
 All as a result of finding incidental spinal Fx on
plain film; MR and CT

 50 were randomly selected for review
• 25 patients (50%) had a T score in the range for
osteoporosis (T Score below -2.5)
• 17 patients (34%) had T scores within the
osteopenic range and were considered to be at risk
of progression to osteoporosis
>80% of patients were considered to be at a significant
risk for further fractures and advised treatment
(lifestyle advice, calcium supplements and anti-
resorptive agents)
 Clear benefits in highlighting possible
osteoporotic fractures in Radiology Reports
 Direct DEXA referrals from radiologists has
successfully aided the identification and
treatment of high risk fracture patients
 Same method as 2014
 100 general CT scans in over 50’s
 January 2015
Criterion Results 2015 Results 2013
Fracture prevalence 20/100 = 20% 31/163 = 23%
Fracture identified 17/20 = 85% 5/37 = 13.5%
Term “fracture” used,
if identified
17/17 = 100% 5/5=100%
Grade given 5/17 = 29% 2/5=40%
Correct description
used
5/17 = 29% 2/5=40%
DEXA
recommendation if no
previous evidence of
osteoporosis
8/20 = 40% 1/4=25%
 Better but room for improvement
 Gap analysis – how can we get detection rates
up, how can we get more referrals for DEXA?
 All about ‘buy in’ from colleagues!
Radiology Fracture Detection

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Radiology Fracture Detection

  • 1. Dr. Amit Gupta Dr. Clare Groves Radiology Department Bradford Royal Infirmary
  • 2.  Bit of a Cinderella topic  Needs a ‘Champion’ in every Trust to show the world how interesting and important it is  Effective fracture prevention need the whole radiology team to ‘buy in’.
  • 3.  Osteoporotic fractures are VERY common  30% of post-menopausal women  Estimated lifetime risk of fracture at hip, lumbar spine or distal forearm is 30-40% in developed countries  Hip fractures are associated with significant increase in morbidity and mortality.
  • 4. Hip FX Vertebral Fx Fragility Fx Probability of osteoporosis in over 50’s Very high High Moderate
  • 5. Hip FX Vertebral Fx Fragility Fx Probability of osteoporosis Very high High Moderate FLS/FRAX Hip Fractures are preventable Intervene Here
  • 6.  Detecting and treating vertebral fractures early can: 1. Prevent new vertebral fractures 2. Prevent significant patient morbidity 3. Prevent hip fractures in the future 4. Save money for the NHS
  • 7.  Current annual UK estimate of hip fractures – 60,000  Increasing 1-3% per year  Hospital costs for a hip fracture £3459 — £33,264 (mean of £12,163) Total annual financial burden £730 million* * T M Lawrence, C T White, R Wenn et al. The current hospital cost of treating hip fractures. Injury, Int. J. Care Injured (2005) 36, 88-91
  • 8.  As health professionals, we are in an ideal position to identify and respond to both suspected and incidental findings of vertebral fractures.
  • 9.  2/3 of vertebral fractures don’t come to clinical attention -‘silent fractures’  Be aware of ‘at risk’ patients  Be aware of history of FFx  Be aware of signs – dowger’s hump
  • 10.  Studies have shown a global 34% false negative rate in analysis of spinal radiographs by radiologists  For general CT, detection rates for spinal fracture have been reported at between 9-16%  Even when vertebral fracture is identified, only one-quarter of patients are started on treatment.
  • 11. Sagittal reconstruction spine • CT Abdomen performed for abdominal pain • Spinal reconstruction not made at the time • Multiple vertebral fractures unreported • Two years later patient sustained a hip fracture • We might have prevented that hip fracture !
  • 12.  Recommendations for plain film reporting vertebral fractures from the IOF:  Scrutinise all images for such fractures  Use clear, unambiguous and accurate terminology – the word ‘fracture’ not ‘collapse’ or other terms  Give number and grades of fractures: mild=1, moderate=2, severe=3.  Indicate if osteoporotic, traumatic or pathological and suggest further appropriate imaging, if relevant.  If osteoporotic in origin, suggested measures should be considered to reduce fracture risk.
  • 13.
  • 14.  Four years ago, no Fracture Liaison Service  Falls and Fragility fracture CQUIN  CJG decided that imaging could be a driver for change.  AUDIT to establish the the current state of play.
  • 15.  Plain film spine reports with regards to:  Fractures being identified  Use of the word ‘Fracture’ in reports  Grading of fracture  Description of fracture morphology  Recommendation for further assessment of osteoporosis.
  • 16. 16 Criterion Standar d Results Fracture Identified 100% 97/103 = 94.2% Term “fracture” used if identified 100% 80/97 = 82.5% Grade given 100% 67/103 = 65% Correct Descriptor used 100% 84/103 = 81.6% Dexa recommended if no previous evidence of osteoporosis 100% 18/82 = 22%
  • 17.  Vertebral fracture identification rate at BRI was reasonable on plain film  Terminology used i.e. the word ‘fracture’ - did not meet expected standards  Grading and description of vertebral fractures did not meet expected standards  As recognised globally, a sufficient number of reports in which fracture is identified did not carry a recommendation regarding further action/assessment.
  • 18.  Reporters of spinal films (consultants, trainees, radiographers) should be aware of the requirement to use the word ‘fracture’ and to number, grade and describe their morphology.  Identification of a fracture should lead to a recommendation for assessment of osteoporosis if no prior evidence for this exists.  Terminology used in reports that is helpful; “Osteoporosis should be considered”, “Has osteoporosis been excluded?” “I suspect this may be osteoporotic”.
  • 19.  The International Osteoporosis Foundation provide an online vertebral fracture teaching program for radiologists; http://www.iofbonehealth.org/vertebral- fracture-teaching-program
  • 20.  First Audit (plain film) was a consciousness- raising exercise.  Second Audit (CT) performed 12 months later
  • 21.  To assess the detection rate and quality of radiological reporting of spinal fractures in CT in accordance to Genant & Wu gold standard  To encourage use of standardised language in reports according to Genant & Wu classification.
  • 22.  Female patient aged over 45  167 consecutive CT examinations were reviewed retrospectively including • CTPA • CT thorax and CT abdomen/Pelvis  4 examinations were excluded as no thin slices were available on PACS to construct sagittal reformat.  163 studies reviewed
  • 23.
  • 24.
  • 25. • 37/163 patients had one or more vertebral fractures (prevalence 22.7%) 37 fracture Present 5 correctly identified (13.5%) all 5 had used word 'fracture' 2 cases Grades given 2 cases Correct discriptors used 3 No grades and incorrect descriptor used 32 not identified (86.5%)
  • 26. 13.5% pick-up rate (in 103 positive cases) 25% had DEXA recommended Plan of Action Introduction of an automated short code Area for improvement The term fracture should be used whenever a vertebral fracture is identified Vertebral Fractures should be graded and categorized Recommendation for DEXA assessment should be included in the report if there is no previous evidence of osteoporosis
  • 27.  Vertebral fracture detection rate at BRI was comparable to published figures, but very poor  NOT utilising the available 3D reconstruction software.
  • 28.  Routine provision of sagittal spinal reconstructions for all general CT studies.  Encouraging radiologists to refer directly for DEXA after finding spinal fractures in patients over 50y using a short code  Consciousness raising again – presentations, flyers, general nagging etc etc.
  • 29.  This has also been audited AND presented at clinical governance ……consciousness-raising
  • 30.  81 direct access DEXA referrals from radiology between January and July 2014  All as a result of finding incidental spinal Fx on plain film; MR and CT   50 were randomly selected for review
  • 31. • 25 patients (50%) had a T score in the range for osteoporosis (T Score below -2.5) • 17 patients (34%) had T scores within the osteopenic range and were considered to be at risk of progression to osteoporosis >80% of patients were considered to be at a significant risk for further fractures and advised treatment (lifestyle advice, calcium supplements and anti- resorptive agents)
  • 32.  Clear benefits in highlighting possible osteoporotic fractures in Radiology Reports  Direct DEXA referrals from radiologists has successfully aided the identification and treatment of high risk fracture patients
  • 33.  Same method as 2014  100 general CT scans in over 50’s  January 2015
  • 34. Criterion Results 2015 Results 2013 Fracture prevalence 20/100 = 20% 31/163 = 23% Fracture identified 17/20 = 85% 5/37 = 13.5% Term “fracture” used, if identified 17/17 = 100% 5/5=100% Grade given 5/17 = 29% 2/5=40% Correct description used 5/17 = 29% 2/5=40% DEXA recommendation if no previous evidence of osteoporosis 8/20 = 40% 1/4=25%
  • 35.
  • 36.  Better but room for improvement  Gap analysis – how can we get detection rates up, how can we get more referrals for DEXA?  All about ‘buy in’ from colleagues!

Notes de l'éditeur

  1. Published figures shows estimated lifetime risk of ♯ amoungst the caucacian woman at above sites – 30-40% life time risk
  2. 10 years between events – FFX and vertebral FX should be seen as warning shots! We can intervene at any stage in the triangle
  3. Risk of death!
  4. These are shocking facts!!
  5. Morphology is important – biconcave is typical of osteoporotic fracture
  6. Descriptor matters – biconcave is often osteoporosis
  7. Genant and WU classification sheets put up in all reporting areas and emailed to consultants and registrars Audit presented at clinical governance and written up in the clinical audit live annals so it could be easily read by other professionals in the hospital
  8. This information was emailed to all radiology consultants and registrars
  9. CT colonogram on 86 year old lady
  10. Sag reconstruction from the colonogram
  11. Prevalence agrees with nationally published data Again a shockingly bad pick up rate nearly 90% of fractures were not detected!
  12. IOF guidelines – use fracture rather than compression, graded according to severity of collapse Categorized whether osteoporotic, pathological or traumatic with further imaging recommended - should this be felt appropriate
  13. IMPORTANT HERE TO EMPHASIS THE NEED FOR BUY IN TO CHANGE FROM THE WHOLE RADIOLOGY DEPARTMENT We shouldn’t be the voice in the wilderness
  14. Risk of fracture was assessed on the basis of patient age and whether or not they were on an aromatase inhibitors or taking glucocorticoids.
  15. Improving steadily BUT still considerable room for improvement I want to see 100% detection of VFs, and 100% of those referred automatically for DEXA
  16. Now have a FLS nurse in place this will help at the fragility fracture stage with FRAX assessment, but vertebral fractures still in the realm of the radiology department Our reporting radiographers have embraced FRAX and vertebral fracture detection with gusto, still problems with radiologists