This report anticipates the rapidly approaching day when the majority of the world’s children will grow up in urban areas. It observes that many of these places are marked by pronounced inequality in power and resources that in turn lead to disparity in children’s survival and development. The report adds to the growing base of evidence and analysis of inequity and the need for strategies to reach excluded children and families wherever they live. It builds on work, by UNICEF and many partners, to show that the children who are most deprived, vulnerable and difficult to reach are to be found not only in remote rural parts but also in the very urban centres that are home to commercial, political and cultural elites.