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Mrs. Stewart
Biology I standard
REVIEW:
 Cell Cycle
 Interphase


G1, S, and G2

 M-phase (mitosis)
 P-M-A-T-C

 Mitosis
 Asexual reproduction
 Produces 2 identical daughter cells
 Daughter cells are diploid
 Daughter cells are identical to parent/mother cell
What differences
can you see?
• How many sets of
chromosomes are in
the cells that
Meiosis produces?
• How many cells
does Meiosis
produce?

• How many
divisions occur
in Meiosis?
Final Products:
Mitosis
Somatic cells in your body have
two sets of chromosomes they are called DIPLOID

Meiosis
Gametes (Sex cells-sperm and
eggs) only have one set (half)
of chromosomes - they are
called HAPLOID
MEIOSIS:
 The process of creating a gamete
What are the steps?
 Phases of Meiosis I
 Prophase I
 Metaphase I
 Anaphase I
 Telophase I
 Cytokinesis

 Interkinesis
 Phases of Meiosis II
 Prophase II
 Metaphase II
 Anaphase II
 Telophase II
 Cytokinesis
Let’s see it in action!
 Meiosis animation
 DNA replicates

Interphase

 Makes the diploid

(2n) cell now be (4n)
 n=number of
chromosome
sets/pairs
 Example: humans
have 46 total
chromosomes, so our
diploid number is 2n
or 2(23) where n = 23
Chromosomes come in matching sets
-these are called homologous pairs
Karyotype
after DNA
replication

Notice how
each
chromosome
has
duplicated
itself.
Prophase I
• Homologous
chromosomes pair
up (forming a
tetrad) - Mom &
Dad go on a date
• Crossing over
occurs
• Chromatids
MAY exchange
portions of
DNA
• Leads to
genetic
variances
Prophase I
 Homologs (homologous

pairs of chromsomes)
form Tetrads
 Crossing Over occurs
Metaphase I
 Spindle fibers attach to the chromosomes
 Homologous chromosomes line up in the middle of

the cell

Anaphase I

• Fibers pull the homologous chromosomes toward
opposite ends of the cell

Telophase I and Cytokinesis
• Nuclear membranes form
• Cell separates into two new cells
Interkinesis
 Resting period between Meiosis I and Meiosis II
 DNA DOES NOT REPLICATE AGAIN HERE!
Meiosis II
 The daughter cells from Meiosis I

divide again WITHOUT replicating
their chromosomes
 That leads to 4 gametes, each with half

the number of chromosomes (haploid)
as the original “mother” cell
Prophase II
 Spindle fibers form and move chromosomes to center

Metaphase II
 Spindle fibers attach to the chromosomes
 chromosomes line up in the middle of the cell – similar to

how they do in Mitosis

Anaphase II
• Fibers pull the sister chromatids toward
opposite ends of the cell

Telophase II and Cytokinesis
• Nuclear membranes form
• Both cells separate – forming 4 new haploid cells
Oogenesis – meiosis in human female
reproductive cells – makes eggs (ovum)
• Total of 4 cells
produced:
• Forms one
usable egg cell
with a large
supply of stored
nutrients.
• The other 3 cells,
called polar
bodies,
disintegrate.
Spermatogenesis – meiosis in human male
reproductive cells to make sperm (spermatazoa)

• Produces 4
viable gametes
• All 4 gametes
produce a long
whip-like tail
Meiosis:
 Cell division necessary for sexual reproduction
 Produces 4 daughter cells
 Daughter cells are Haploid

 Daughter cells are gametes (sexual repro. cells)
 2 nuclear/cellular divisions
 Vital to maintain correct number of offspring in

sexually reproducing organisms
 Crossing over = opportunity for genetic variability
Differentiate
Mitosis

Meiosis

 Asexual reproduction

 Used for sexual reproduction

 Produces 2 daughter cells

 Produces 4 daughter cells

 Daughter cells are diploid

 Daughter cells are Haploid

 Daughter cells are

 Daughter cells are genetically

identical to each other
and to parent cell
 Produces somatic cells
 One cell/nuclear division

different from each
other, and from parent cell
 Produces gametes
 Two nuclear/cellular divisions
Human chromosomal diseases
**Mistake in meiosis can lead to an incorrect
chromosomal number, causing
consequences for offspring**
 Down’s syndrome (extra chromosome #21)
 Turner’s syndrome (missing or incomplete X
chromosome in girls)

 Klinefelter’s syndrome (males that have an extra X
chromosome [XXY])
Think – Pair – Share
 How does a baby with Down’s Syndrome

end up with 3 chromosome #21s?
Video
 Meiosis square dance
Mitosis vs. meiosis

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Mitosis vs. meiosis

  • 2. REVIEW:  Cell Cycle  Interphase  G1, S, and G2  M-phase (mitosis)  P-M-A-T-C  Mitosis  Asexual reproduction  Produces 2 identical daughter cells  Daughter cells are diploid  Daughter cells are identical to parent/mother cell
  • 3.
  • 4. What differences can you see? • How many sets of chromosomes are in the cells that Meiosis produces? • How many cells does Meiosis produce? • How many divisions occur in Meiosis?
  • 5. Final Products: Mitosis Somatic cells in your body have two sets of chromosomes they are called DIPLOID Meiosis Gametes (Sex cells-sperm and eggs) only have one set (half) of chromosomes - they are called HAPLOID
  • 6. MEIOSIS:  The process of creating a gamete
  • 7. What are the steps?  Phases of Meiosis I  Prophase I  Metaphase I  Anaphase I  Telophase I  Cytokinesis  Interkinesis  Phases of Meiosis II  Prophase II  Metaphase II  Anaphase II  Telophase II  Cytokinesis
  • 8.
  • 9. Let’s see it in action!  Meiosis animation
  • 10.  DNA replicates Interphase  Makes the diploid (2n) cell now be (4n)  n=number of chromosome sets/pairs  Example: humans have 46 total chromosomes, so our diploid number is 2n or 2(23) where n = 23
  • 11. Chromosomes come in matching sets -these are called homologous pairs
  • 13. Prophase I • Homologous chromosomes pair up (forming a tetrad) - Mom & Dad go on a date • Crossing over occurs • Chromatids MAY exchange portions of DNA • Leads to genetic variances
  • 14. Prophase I  Homologs (homologous pairs of chromsomes) form Tetrads  Crossing Over occurs
  • 15. Metaphase I  Spindle fibers attach to the chromosomes  Homologous chromosomes line up in the middle of the cell Anaphase I • Fibers pull the homologous chromosomes toward opposite ends of the cell Telophase I and Cytokinesis • Nuclear membranes form • Cell separates into two new cells
  • 16.
  • 17. Interkinesis  Resting period between Meiosis I and Meiosis II  DNA DOES NOT REPLICATE AGAIN HERE!
  • 18. Meiosis II  The daughter cells from Meiosis I divide again WITHOUT replicating their chromosomes  That leads to 4 gametes, each with half the number of chromosomes (haploid) as the original “mother” cell
  • 19. Prophase II  Spindle fibers form and move chromosomes to center Metaphase II  Spindle fibers attach to the chromosomes  chromosomes line up in the middle of the cell – similar to how they do in Mitosis Anaphase II • Fibers pull the sister chromatids toward opposite ends of the cell Telophase II and Cytokinesis • Nuclear membranes form • Both cells separate – forming 4 new haploid cells
  • 20.
  • 21. Oogenesis – meiosis in human female reproductive cells – makes eggs (ovum) • Total of 4 cells produced: • Forms one usable egg cell with a large supply of stored nutrients. • The other 3 cells, called polar bodies, disintegrate.
  • 22. Spermatogenesis – meiosis in human male reproductive cells to make sperm (spermatazoa) • Produces 4 viable gametes • All 4 gametes produce a long whip-like tail
  • 23. Meiosis:  Cell division necessary for sexual reproduction  Produces 4 daughter cells  Daughter cells are Haploid  Daughter cells are gametes (sexual repro. cells)  2 nuclear/cellular divisions  Vital to maintain correct number of offspring in sexually reproducing organisms  Crossing over = opportunity for genetic variability
  • 24. Differentiate Mitosis Meiosis  Asexual reproduction  Used for sexual reproduction  Produces 2 daughter cells  Produces 4 daughter cells  Daughter cells are diploid  Daughter cells are Haploid  Daughter cells are  Daughter cells are genetically identical to each other and to parent cell  Produces somatic cells  One cell/nuclear division different from each other, and from parent cell  Produces gametes  Two nuclear/cellular divisions
  • 25. Human chromosomal diseases **Mistake in meiosis can lead to an incorrect chromosomal number, causing consequences for offspring**  Down’s syndrome (extra chromosome #21)  Turner’s syndrome (missing or incomplete X chromosome in girls)  Klinefelter’s syndrome (males that have an extra X chromosome [XXY])
  • 26. Think – Pair – Share  How does a baby with Down’s Syndrome end up with 3 chromosome #21s?