A drug to treat baldness

1. A drug to treat baldness
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2. Contd…
In some good news for people with receding hairlines, scientists have identified
new drugs that could stimulate rapid and robust hair growth, offering a potential
cure for baldness.The drugs inhibit a family of enzymes inside hair follicles that are
suspended in a resting state, restoring hair growth, researchers said.
In experiments with mouse and human hair follicles, Angela M Christiano from
Columbia University Medical Center and colleagues found that drugs that inhibit
the Janus kinase (JAK) family of enzymes promote rapid and robust hair growth
when directly applied to the skin.
The study raises the possi bility that drugs known as JAK inhibitors could be used to
restore hair growth in multiple forms of hair loss such as that induced by male
pattern baldness, and additional types that occur when hair follicles are trapped in
a resting state, researchers said. Two JAK inhibitors have been approved by the US
Food and Drug Administration (FDA). One is approved for treatment of blood
diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib).
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