Jürgen C. Becker, MD, PhD, Sunandana Chandra, MD, MS, Geoffrey T. Gibney, MD, and Guilherme Rabinowits, MD, discuss merkel cell carcinoma in this CME/CNE activity titled "Progress-in-Practice Master Class, The Coming-of-Age of Immunotherapy in Merkel Cell Carcinoma: Rationale, Evidence, and Practicalities". For the full presentation, downloadable practice aids, complete CME/CNE information, and to apply for credit, please visit us at http://bit.ly/2rWdqUM. CME/CNE credit will be available until June 20, 2018.