Diabetic neuropathy is nerve damage caused by prolonged high blood sugar levels in diabetes. Current treatments focus on managing symptoms but cannot reverse nerve damage. Stem cell therapy may offer an innovative treatment by promoting tissue regeneration through stem cells' ability to differentiate into nerve cells and release growth factors. Mesenchymal stem cells are commonly used and may improve nerve function, reduce pain, and enhance quality of life for patients with diabetic neuropathy.

1. DiabeticNeuropathy:
ThePromiseofStem
CellTherapy
D r . D a v i d G r e e n e | R 3 S t e m C e l l

2. Introduction
• Diabetic neuropathy is a common
complication of diabetes, characterized
by nerve damage.
• Conventional treatments often provide
limited relief; however, stem cell
therapy shows promising
advancements.
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3. UnderstandingDiabetic
Neuropathy
• Diabetic neuropathy is a result of
prolonged high blood sugar levels
damaging the nerves.
• It can lead to symptoms such as
numbness, tingling, pain, and loss of
sensation in the affected areas.
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4. ChallengesofTraditional
Treatments
• Traditional approaches focus on symptom
management, pain relief, and blood sugar
control.
• Limitations include incomplete efficacy, side
effects, and inability to reverse nerve damage.
• Need for innovative therapies to address the
underlying pathology.
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5. StemCellTherapy
Overview
• Stem cell therapy involves the use of
specialized cells that can differentiate into
various cell types.
• Stem cells can promote tissue repair and
regeneration, making them a potential
treatment option for diabetic neuropathy.
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6. TypesofStemCellsUsed
• Mesenchymal stem cells (MSCs) are
commonly used in stem cell therapy for
diabetic neuropathy.
• MSCs have the ability to differentiate into
nerve cells and release factors that
promote nerve regeneration.
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7. MechanismsofAction
• Stem cells release growth factors, cytokines,
and extracellular vesicles that promote
tissue repair and regeneration.
• They can differentiate into nerve cells and
integrate into damaged neural tissue.
• Paracrine effects modulate the immune
response and reduce inflammation.
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8. BenefitsofStemCell
Therapy
Potential benefits of stem cell therapy for
diabetic neuropathy include:
• Improved nerve function and sensation
• Reduction in pain and discomfort
• Enhanced quality of life for patients
• Offers a targeted and personalized
approach to treatment
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9. Conclusion
• Stem cell therapy holds great promise
for treating diabetic neuropathy.
• Advances in this field offer hope for
patients with limited treatment
options.
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11. ThankyouFor
Reading
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