Lyophilisation (also known as freeze drying or cryodesiccation) is an operation used for the preparation of stable pharmaceutical products. The market for lyophilisation has enjoyed strong growth in recent years, driven by new products and drug classes, especially in biotechnology. In recent years, the number of such products has been growing steadily. It is predicted that half of the injectable drugs approved in the next five years will require lyophilisation. In our new report, we predict that the global lyophilisation market will grow steadily in revenue and unit sales from 2010 to 2025.Lyophilisation for Pharmaceuticals: Technology and Market 2010-2025 shows how the sector will be driven by the introduction of new products, particularly monoclonal antibodies (MAbs) and other proteins. There will also be developments in drying and packaging technologies. Products benefiting from lyophilisation technology include:' Active pharmaceutical ingredients (API)' Vaccines' Diagnostic kits' Reagents' Proteins' Hormones' Viral preparations' Bacterial preparations' Tissue preparations' Blood plasma products' Enzymes' Pathological samples' Nutraceuticals' Vitamins' Herbal extracts.There is an increased demand from pharmaceutical companies for manufacturing equipment and services for lyophilisation. As a result, the lyophilisation sector is one of the fastest growing in the global healthcare industry. All the therapeutic segments using lyophilisation have been expanding, but which will grow fastest in years to come' What are the main therapeutic and commercial trends to watch' How will the worldwide market for freeze-drying technology and services perform from 2010 to 2025' Our new report answers questions such as those, providing the information that you need.Our report shows how the lyophilisation market will experience strong revenue growth from 2010 to 2025, with greater demand for injectable drugs and vaccines requiring drying technologies. There are under-met needs for improved stability and cost effectiveness, as well as for more convenience in transport, storage and use of therapeutic agents. Rapid stabilisation, long-term product stability, ease of reconstitution and process advantages for heat-sensitive products will drive growth of the lyophilisation technology and services market. From 2010 onwards, there will be developments in freeze-drying technology that will benefit the sector and its customers, extending performance and applications.Detailed analysis of the lyophilisation industry and marketLyophilisation for Pharmaceuticals: Technology and Market 2010-2025 examines that sector through a comprehensive review of information sources, primary and secondary. This report provides our sales forecasts, market share analyses, discussions of technological developments and analyses of commercial drivers and restraints, including SWOT analysis. There are over 70 tables and figures included and an interview with an industry expert. The result is a comprehensive market- and industry-centred study, with detailed analyses and informed opinion to benefit your work.Why you should buy Lyophilisation for Pharmaceuticals: Technology and Market 2010-2025This report gives you the following benefits in particular:' You will receive a comprehensive analysis of the prospects for lyophilisation products and services, including predicted revenues and other data, by overall market and main subgroup/application' You will find out how the lyophilisation industry and market will change from 2010 to 2025, with sales forecasts for the global market and leading national markets (US, Japan, UK, Germany, France, Spain, Italy, China and India)' You will discover the prospects for relevant therapeutic classes, with forecasts and other data for 2010 to 2025' You will discover how the lyophilisation products and services sector is evolving to deliver improved ease of use, safety, product stability and convenience of transport/storage' You will analyse the dri

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Lyophilisation for Pharmaceuticals: Technology and Market
2010-2025
Published on June 2010
Report Summary
Lyophilisation (also known as freeze drying or cryodesiccation) is an operation used for the preparation of stable pharmaceutical
products. The market for lyophilisation has enjoyed strong growth in recent years, driven by new products and drug classes,
especially in biotechnology. In recent years, the number of such products has been growing steadily. It is predicted that half of the
injectable drugs approved in the next five years will require lyophilisation. In our new report, we predict that the global lyophilisation
market will grow steadily in revenue and unit sales from 2010 to 2025.
Lyophilisation for Pharmaceuticals: Technology and Market 2010-2025 shows how the sector will be driven by the introduction of new
products, particularly monoclonal antibodies (MAbs) and other proteins. There will also be developments in drying and packaging
technologies. Products benefiting from lyophilisation technology include:
' Active pharmaceutical ingredients (API)
' Vaccines
' Diagnostic kits
' Reagents
' Proteins
' Hormones
' Viral preparations
' Bacterial preparations
' Tissue preparations
' Blood plasma products
' Enzymes
' Pathological samples
' Nutraceuticals
' Vitamins
' Herbal extracts.
There is an increased demand from pharmaceutical companies for manufacturing equipment and services for lyophilisation. As a
result, the lyophilisation sector is one of the fastest growing in the global healthcare industry. All the therapeutic segments using
lyophilisation have been expanding, but which will grow fastest in years to come' What are the main therapeutic and commercial
trends to watch' How will the worldwide market for freeze-drying technology and services perform from 2010 to 2025' Our new report
answers questions such as those, providing the information that you need.
Our report shows how the lyophilisation market will experience strong revenue growth from 2010 to 2025, with greater demand for
injectable drugs and vaccines requiring drying technologies. There are under-met needs for improved stability and cost effectiveness,
as well as for more convenience in transport, storage and use of therapeutic agents. Rapid stabilisation, long-term product stability,
ease of reconstitution and process advantages for heat-sensitive products will drive growth of the lyophilisation technology and
services market. From 2010 onwards, there will be developments in freeze-drying technology that will benefit the sector and its
customers, extending performance and applications.
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Detailed analysis of the lyophilisation industry and market
Lyophilisation for Pharmaceuticals: Technology and Market 2010-2025 examines that sector through a comprehensive review of
information sources, primary and secondary. This report provides our sales forecasts, market share analyses, discussions of
technological developments and analyses of commercial drivers and restraints, including SWOT analysis. There are over 70 tables
and figures included and an interview with an industry expert. The result is a comprehensive market- and industry-centred study, with
detailed analyses and informed opinion to benefit your work.
Why you should buy Lyophilisation for Pharmaceuticals: Technology and Market 2010-2025
This report gives you the following benefits in particular:
' You will receive a comprehensive analysis of the prospects for lyophilisation products and services, including predicted revenues
and other data, by overall market and main subgroup/application
' You will find out how the lyophilisation industry and market will change from 2010 to 2025, with sales forecasts for the global market
and leading national markets (US, Japan, UK, Germany, France, Spain, Italy, China and India)
' You will discover the prospects for relevant therapeutic classes, with forecasts and other data for 2010 to 2025
' You will discover how the lyophilisation products and services sector is evolving to deliver improved ease of use, safety, product
stability and convenience of transport/storage
' You will analyse the drivers, restraints, competition and opportunities influencing the lyophilisation product and service industries and
markets
' You will receive expert views from our survey, including an interview transcript
' You will investigate developments in that sector ' technological and commercial ' with the most exciting trends and opportunities
highlighted.
You can obtain this report today
Nobody with an interest in drug packaging, drug delivery and pharmaceutical biotechnology should overlook our new study. Success
from 2010 onwards will be characterised by greater product stability and more-convenient presentation of high-value pharmaceuticals,
with the lyophilisation sector benefiting. Rising healthcare demands ' coupled with benefits to pharma stakeholders ' are drivers of this
market. Do you want to harness those opportunitie
Table of Content
Table of Content
1. Executive Summary
1.1 Lyophilisation Market Review
1.2 Aims, Scope and Format of the Report
1.3 Research & Analysis Methods
2. Introduction to Lyophilisation (Freeze Drying)
2.1 Introduction
2.1.1 What is Freeze Drying'
2.1.2 Why Freeze Dry'
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2.1.3 A Brief History
2.2 General Description of the Process
2.2.1 Freezing
2.2.2 Primary Drying (Sublimation)
2.2.3 Secondary Drying (Desorption)
2.2.4 Freeze Drying Equipment
2.2.4.1 Components of the Freeze Drier
2.2.4.1.1 Drying Chamber
2.2.4.1.2 Condenser
2.2.4.1.3 Vacuum Pump
2.2.4.1.4 Refrigeration System
2.2.4.1.5 Control Facilities
2.2.4.2 Rotary Freeze Dryers
2.2.4.3 Manifold Freeze Dryers
2.2.4.4 Tray Freeze Dryers
2.3 Applications of Lyophilisation
2.3.1 Pharmaceutical and Biotechnology Industry
2.3.2 Other Chemical and Technological Sectors
2.3.3 Veterinary Applications
2.3.4 Food Industry Applications
2.3.4.1 What Products are Freeze Dried'
2.3.4.2 How do Freeze Dryers for Food Differ from those for Pharmaceutical Applications'
2.3.5 Other Applications for Lyophilisation
3. Leading National Markets for Lyophilisation
3.1 The World Lyophilisation Technology Market in 2010
3.2 Growing Market for Lyophilisation Technology and Services
3.2.1 Sales Forecast for Overall Lyophilisation Market, 2010-2016
3.2.2 Sales Forecast for Overall Lyophilisation Market, 2017-2025
3.3 Breakdown of the Global Lyophilisation Market
3.3.1 Sales Forecast for cGMP Lyophilisers, 2010-2016
3.3.2 Sales Forecast for cGMP Lyophilisers, 2017-2025
3.3.3 Sales Forecast for Laboratory Lyophilisers, 2010-2016
3.3.4 Sales Forecast for Laboratory Lyophilisers, 2017-2025
3.3.5 Sales Forecast for Lyophilisation Services, 2010-2016
3.3.6 Sales Forecast for Lyophilisation Services, 2017-2025
3.4 Leading National Markets for Lyophilisation Technology, 2010-2025
3.4.1 Leading National Markets for Lyophilisation Technology, 2010-2025
3.4.2 The Japanese Lyophilisation Technology Market, 2010-2025
3.4.3 The Leading European Lyophilisation Technology Markets, 2010-2025
3.4.4 Emerging Economy Lyophilisation Technology Markets
3.4.5 The Chinese Lyophilisation Technology Market, 2010-2025
3.4.6 The Indian Lyophilisation Technology Market, 2010-2025
4. Worldwide Market for Lyophilised Products and Technology
4.1 Therapeutic Areas Offering Growth Opportunities
4.1.1 The Leading Biotech Therapy Classes, 2010-2025
4.1.2 The Top 10 Biotech Therapy Classes in 2009
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4.1.3 The Oncology Class Currently Leads the Biotech Market
4.1.3.1 Long-Term Prospects in Oncology & Implications for Lyophilisation Market
4.1.4 The Human Insulins Class will Exhibit Strong Growth
4.1.5 Immunosuppressive Agents, 2010-2025
4.1.6 Autoimmune Agents Show Promising Growth - Will it Last'
4.1.7 Erythropoietin Products - How will Reported Safety Affect Sales'
4.1.7.1 Erythropoietin Products Forecast, 2010-2025
4.1.8 Immunostimulating Agents - Sales Prospects
4.1.9 The Interferons Class will Show an Increase in Revenues from 2010-2015
4.1.9.1 Long-Term Forecast for the Interferons Class
4.1.10 Will Pure Vaccine Sales Continue to Decline After 2015'
4.1.10.1 Will Pure Vaccines Sales Continue to Decline after 2015'
4.1.11 Blood Coagulation Factors will Show Steady Growth
4.1.12 Growth Hormones Forecast, 2010-2025
4.2 Summary of World Market Forecasts
4.2.1 The Top 10 Biotech Therapy Classes, 2010-2025
4.2.2 Lyophilisation Market: a Rapidly Expanding Segment of the Global Pharma Sector
5. Some Prominent Companies in the Lyophilisation Industry and Market
5.1 Introduction
5.2 GEA Lyophil
5.2.1 Overview
5.2.2 Capabilities of GEA Lyophil
5.2.3 Lyophilisation Production Systems
5.2.4 GEA Lyophil's Fast Track Project Management
5.2.5 GEA's Thermodynamic Lyophilisation Control
5.2.6 GEA's Retrofits of Lyophilisers
5.2.7 GEA's VAPOVAC: Technology for Freeze Dryer Sterilisation
5.2.8 GEA's Lyovac Production Lyophilisers
5.2.9 GEA Lyophil's Pilot Freeze Dryers
5.2.10 ALUS: GEA Lyophil's Automatic Loading and Unloading Systems for Lyophilisers
5.2.11 GEA Lyophil's Research and Development Freeze Dryers
5.3 Labconco Corporation
5.3.1 Overview
5.3.2 Global Presence
5.3.3 Product Focus
5.3.3.1 Freeze Dry Systems
5.3.3.2 Dry Ice Bench-top Freeze Dry System
5.3.3.3 FreeZone Bench-top Freeze Dry Systems
5.3.3.4 FreeZone Console Freeze Dry Systems
5.3.3.5 FreeZone Cascade Freeze Dry Systems
5.3.3.6 FreeZone Triad Freeze Dry Systems
5.3.4 Labconco Freeze Dry Accessories
5.3.5 R&D
5.3.6 Future Outlook
5.4 Vetter Pharma-Fertigung
5.4.1 Overview
5.4.2 Global Presence
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5.4.3 Business Interests
5.4.3.1 Vetter Development Service
5.4.3.2 Vetter Commercial Manufacturing
5.4.3.3 Vetter Solutions
5.4.4 Capabilities
5.4.5 R&D
5.4.6 Product Focus
5.4.6.1 Dual-Chamber Technology
5.4.7 Future Outlook
5.5 Piramal Healthcare
5.5.1 Overview
5.5.2 Piramal's Corporate Restructuring
5.5.3 Therapeutic Interests
5.5.4 Global Presence
5.5.5 Strengths & Capabilities
6. SWOT Analysis of the Lyophilisation Technology Market
6.1 Introduction
6.2 Commercial Drivers of the Lyophilisation Technology Market
6.3 Commercial Restraints for the Lyophilisation Technology Market
6.3.1 High Entry Barriers to Sector
6.3.2 Product Formulation Challenges
6.3.3 R&D Stage for Lyophilised Products
6.3.4 Scale-up Stage for Lyophilised Products
6.3.5 Large Scale Production Stage for Lyophilised Products
6.3.6 Main Challenges in a Freeze-Drying Plant
6.3.7 Main Issues in Production
6.3.8 Typical Deficiencies in a Freeze-Drying Process
6.4 Challenges Facing the Lyophilisation Technology Industry and Market
6.4.1 Spray Drying of Biopharmaceuticals
6.4.2 Other Methods in Development
6.4.3 Roche's Precipitation Method
6.5 Expert Interview: Dr Steven Nail, Baxter Healthcare, USA
6.5.1 Current Market Worth for Freeze-drying
6.5.2 Products Suitable for Lyophilisation
6.5.3 Percentage of Lyophilised Products on Market
6.5.4 Key Areas for Research and Development
6.5.5 On Advantages of Lyophilisation
6.5.6 On Advantages of Lyophilisation over Other Drug Delivery Systems
6.5.7 On Drawbacks of Lyophilisation over Other Technologies
6.5.8 On Novel Technologies and Developments
6.6 Summary
7. Conclusions: Lyophilisation Technology and Services are a Growth Market
7.1 Overview
7.2 Prominent Companies in the Market
7.3 Commercial Drivers of the Lyophilisation Market
7.4 Future Outlook and Concluding Remarks
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Lists of Tables
Table 3.1 Lyophilisation Technology and Services: World Sales Forecast, 2010-2016
Table 3.2 Lyophilisation Technology and Services: World Sales Forecast, 2017-2025
Table 3.3 cGMP Lyophilisers: World Sales Forecast, 2010-2016
Table 3.4 cGMP Lyophilisers: World Sales Forecast, 2017-2025
Table 3.5 Laboratory Lyophilisers: World Sales Forecast, 2010-2016
Table 3.6 Laboratory Lyophilisers: World Sales Forecast, 2017-2025
Table 3.7 Lyophilisation Services Market: World Sales Forecast, 2010-2016
Table 3.8 Lyophilisation Services Market: World Sales Forecast, 2017-2025
Table 3.9 Lyophilisation Market: World Sales Forecast, 2010-2016
Table 3.10 Lyophilisation Market: World Sales Forecast, 2017-2025
Table 3.11 Leading Lyophilisation National Market Forecasts, 2010-2015, 2020 & 2025
Table 4.1 The Top 10 Biotech Therapy Classes, 2009
Table 4.2 Oncology Class: World Sales Forecast, 2010-2016
Table 4.3 Oncology Class: World Sales Forecast, 2017-2025
Table 4.4 Human Insulins Class: World Sales Forecast, 2010-2016
Table 4.5 Human Insulins Class: World Sales Forecast, 2017-2025
Table 4.6 Immunosuppressive Agents Class: World Sales Forecast, 2010-2016
Table 4.7 Immunosuppressive Agents Class: World Sales Forecast, 2017-2025
Table 4.8 Autoimmune Agents Class: World Sales Forecast, 2010-2016
Table 4.9 Autoimmune Agents Class: World Sales Forecast, 2017-2025
Table 4.10 Erythropoietin Products Class: World Sales Forecast, 2010-2016
Table 4.11 Erythropoietin Products Class: World Sales Forecast, 2017-2025
Table 4.12 Immunostimulating Agents Class: World Sales Forecast, 2010-2016
Table 4.13 Immunostimulating Agents Class: World Sales Forecast, 2017-2025
Table 4.14 Interferons Class: World Sales Forecast, 2010-2016
Table 4.15 Interferons Class: World Sales Forecast, 2017-2025
Table 4.16 Pure Vaccines Class: World Sales Forecast, 2010-2016
Table 4.17 Pure Vaccines Class: World Sales Forecast, 2017-2025
Table 4.18 Blood Coagulation Factors Class: World Sales Forecast, 2010-2016
Table 4.19 Blood Coagulation Factors Class: World Sales Forecast, 2017-2025
Table 4.20 Growth Hormones Class: World Sales Forecast, 2010-2016
Table 4.21 Growth Hormones Class: World Sales Forecast, 2017-2025
Table 4.22 Leading Biotech Therapy Classes: World Sales Forecasts, 2010-2016
Table 4.23 Leading Biotech Therapy Classes: World Sales Forecasts, 2017-2025
Table 5.1 GEA Pharma Systems: A Historical Perspective
Table 5.2 Labconco: A Brief History
Table 5.3 Leading Companies in the Lyophilisation Market, 2010
Table 6.1 SWOT Analysis for the Lyophilisation Sector: Strengths and Weaknesses, 2010-2025
Table 6.2 SWOT Analysis for the Lyophilisation Sector: Opportunities and Threats, 2010-2025
Table 6.3 Advantages of a Spray Dryer for Drying Applications, 2010
Table 6.4 Comparison of Lyophilisation and Spray Drying, 2010
Table 7.1 Lyophilisation Market: World Sales Forecast, 2010, 2012, 2015, 2018, 2020 and 2025
Lists of Figures
Figure 2.1 The Freeze Drying Process
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Figure 2.2 Components of a Typical Freeze Dryer
Figure 2.3 Typical Lyophilisation (Freeze Drying) Process
Figure 3.1 Lyophilisation Technology and Services: World Sales Forecast, 2010-2016
Figure 3.2 Lyophilisation Technology and Services: World Sales Forecast, 2017-2025
Figure 3.3 cGMP Lyophilisers: World Sales Forecast, 2010-2016
Figure 3.4 cGMP Lyophilisers: World Sales Forecast, 2017-2025
Figure 3.5 Laboratory Lyophilisers: World Sales Forecast, 2010-2016
Figure 3.6 Laboratory Lyophilisers: World Sales Forecast, 2017-2025
Figure 3.7 Lyophilisation Services Market: World Sales Forecast, 2010-2016
Figure 3.8 Lyophilisation Services Market: World Sales Forecast, 2017-2025
Figure 3.9 Lyophilisation Market: World Sales Forecast, 2010-2025
Figure 3.10 US Lyophilisation Market: Sales Forecast, 2010-2025
Figure 3.11 Other Leading Lyophilisation National Markets: Sales Forecasts, 2010-2025
Figure 3.12 Lyophilisation Sales Shares in Leading National Markets, 2010
Figure 3.13 Lyophilisation Sales Shares in Leading National Markets, 2015
Figure 3.14 Lyophilisation Sales Shares in Leading National Markets, 2020
Figure 3.15 Lyophilisation Sales Shares in Leading National Markets, 2025
Figure 4.1 Oncology Class: World Sales Forecast, 2010-2025
Figure 4.2 Human Insulins Class: World Sales Forecast, 2010-2025
Figure 4.3 Immunosuppressive Agents Class: World Sales Forecast, 2010-2025
Figure 4.4 Autoimmune Agents Class: World Sales Forecast, 2010-2025
Figure 4.5 Erythropoietin Products Class: World Sales Forecast, 2010-2025
Figure 4.6 Immunostimulating Agents Class: World Sales Forecast, 2010-2025
Figure 4.7 Interferons Class: World Sales Forecast, 2010-2025
Figure 4.8 Pure Vaccines Class: World Sales Forecast, 2010-2025
Figure 4.9 Blood Coagulation Factors Class: World Sales Forecast, 2010-2025
Figure 4.10 Growth Hormones Class: World Sales Forecast, 2010-2025
Figure 4.11 Leading Biotech Therapy Classes: World Sales Forecast, 2010-2025
Figure 4.12 Top Ten Therapy Classes: World Sales, 2009, 2015 & 2025
Figure 7.1 Lyophilisation Market: World Sales Forecast, 2010-2025
Companies Listed
AAIPharma Services
ABC Laboratories
Allergan
Almac
Althea Technologies
Azopharma Product Development Group
Baxter Healthcare
B. Braun Melsungen
Ben Venue Laboratories
Bilcare Global Clinical Supplies, Americas
Biopharma Process Systems
Biopharma Technology
Cangene Biopharma
Catalent Pharma Solutions
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CMC Biologics
Coldstream Laboratories
DSM Pharmaceuticals
European Medicines Agency (EMEA)
Food and Drug Administration (US FDA)
Formatech
Freezedry Specialties
Fresenius Kabi Product Partnering
FTS Systems
Galenix
GEA Lyophil (GEA Pharma Systems, GEA Group)
Genentech
Girindus America
Gland Pharma
GP Pharm
Grand River Aseptic Pharmaceutical Packaging
Haemtech Biopharma Services
Haupt Pharma
HollisterStier Contract Manufacturing
Hospira One 2 One
Hovione
Huapont Pharm. Co.
Hyaluron Contract Manufacturing (HCM)
IDT Biologika
IMA Edwards Pharmaceutical Systems
Impact Analytical
Intas Biopharmaceuticals
Irvine Pharmaceutical Services
JHP Pharmaceuticals
Jouan Nordic
KBI Biopharma
King Pharmaceuticals
KP Pharmaceutical Technology
Lab. PiSA
Labconco Corporation
Lampire Biological Laboratories
Legacy Pharmaceuticals International
Lonza
Lyophilisation Services of New England (LSNE)
Lyophilisation Technology
Martin Christ Gefriertrocknungsanlagen
MedPharm
Miltenyi Biotec, Bioprocess Division
Ministry of Health, Labour and Welfare (Japan)
Molecular Profiles
National Archives and Records Administration (NARA), Document Conservation Laboratory (DCL)
Nextar Chempharma Solutions (formerly Aminolab Pharma)
NextPharma
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Nicholas Piramal
Niro
Nycomed
Oakwood Laboratories
OctoPlus
Om Bhagwati Labelling Technologies
Omnia Biologics
One 2 One Global Pharmaceutical Services (Hospira)
Optima Machinery Corporation
Oregon Freeze Dry
Oso BioPharmaceutical Manufacturing
Overlook Industries
Patheon
Pfizer CentreSource
Pharmatek Laboratories
Piramal Healthcare
PolyPeptide Laboratories
Quality Assistance
Rana Diagnostics
Reig Jofré Group
RFCL
Richman Chemical
Roche
SAFC Pharma
Sandoz (part of Novartis)
Scripps Laboratories
Serail Freeze-Drying Systems
SL Pharma Labs
Solvay
SP Formulations
SP Industries
SRI International
Stason Pharmaceuticals.
Therapure Biopharma
Thermo Fisher Scientific
University of Iowa Pharmaceuticals (UIP)
USIFROID
Vectech
Vetter Pharma International
Vetter Pharma-Fertigung
Walter Reed Pilot Bioproduction Facility
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