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2/4/2012   Dr. Riaz A. Bhutto   1
Public Health Methodologies
                   Biostatistics
2/4/2012             Dr. Riaz A. Bhutto   2
Ratio
• is a relationship between two numbers of the
  same
  kind (e.g., objects, persons, students, spoonful
  s, units of whatever identical dimension)
• usually expressed as "a to b" or a:b
• For example, suppose I have 10 pairs of socks
  for every pair of shoes then the ratio of
  shoes:socks would be 1:10 and the ratio of
  socks:shoes would be 10:1

2/4/2012             Dr. Riaz A. Bhutto           3
Coefficient of variation
• Is the ratio of the standard deviation to the
  mean
• Used to compare the relative variation or spread
  of the distribution of different series, samples, or
  population; or the different characteristics of a
  single series
• Expressed in percentage
                         SD
              CV (%) = -------- X 100
                         __
                          X
2/4/2012               Dr. Riaz A. Bhutto            4
Example
• In a medical college, the mean weight of 100
  medical students is 140 lbs, with S.D of 28 lbs.
  The mean height of these students is 66”, with
  S.D of 6”
• CV for weight = 28/140 x 100 = 20%
  CV for height = 6/66 x 100 = 9%
• Based on the CV, therefore, the relative spread
  of weight among the students is greater than
  that of height
2/4/2012             Dr. Riaz A. Bhutto          5
Percentile
• Are the points which divide all
  measurements/value into 100 equal parts
• In statistics, a percentile (or centile) is the
  value of a variable below which a
  certain percent of observations fall.
• For example, the 20th percentile is the value
  (or score) below which 20 percent of the
  observations may be found.


2/4/2012              Dr. Riaz A. Bhutto            6
• The 25th percentile is also known as the
    first quartile (Q1), the 50th percentile as
    the median or second quartile (Q2), and the
    75th percentile as the third quartile (Q3).




2/4/2012             Dr. Riaz A. Bhutto           7
Normal Distribution
• Data can be "distributed" (spread out) in
  different ways.
• It can be spread out more on the left ... or
  more on the right




• Or it can be all jumbled up



2/4/2012              Dr. Riaz A. Bhutto         8
A Normal Distribution
But there are many cases where the data tends to be around a central value with
no bias left or right, and it gets close to a "Normal Distribution" like this:




        The "Bell Curve" is a Normal Distribution.


                                 It is often called a "Bell Curve"
                                 because it looks like a bell.

  2/4/2012                        Dr. Riaz A. Bhutto                        9
Many things closely follow a Normal Distribution:



     Heights of people
     Size of things produced by machines
     Errors in measurements
     Blood pressure
     Marks on a test

    We say the data is "normally distributed".

2/4/2012               Dr. Riaz A. Bhutto           10
The Normal Distribution has:
           mean = median = mode
           symmetry about the center
           50% of values less than the mean
           and 50% greater than the mean




2/4/2012               Dr. Riaz A. Bhutto     11
68% of values are within
                      1 standard deviation of the mean




                     95% are within 2 standard deviations




                    99.7% are within 3 standard deviations




2/4/2012   Dr. Riaz A. Bhutto                                12
Example: 95% of students at school are between 1.1m and 1.7m tall.
Assuming this data is normally distributed can you calculate the mean and standard
deviation?
The mean is halfway between 1.1m and 1.7m:
                       Mean = (1.1m + 1.7m) / 2 = 1.4m

              95% is 2 standard
              deviations either side
              of the mean (a total of
              4 standard deviations)
              so:
               1 standard deviation
                = (1.7m-1.1m) / 4
               = 0.6m / 4 = 0.15m
                     And this is the result:


    It is good to know the standard deviation, because we can say that any value is:
    likely to be within 1 standard deviation (68 out of 100 will be)
    very likely to be within 2 standard deviations (95 out of 100 will be)
    almost certainly within 3 standard Riaz A. Bhutto (997 out of 1000 will be)
   2/4/2012                           Dr. deviations                            13
Standard Scores
     The number of standard deviations from the
     mean is also called the "Standard
     Score", "sigma" or "z-score". Get used to
     those words!
Example: In that same school one of your friends is 1.85m tall
You can see on the bell curve that 1.85m is 3
standard deviations from the mean of 1.4, so:
Your friend's height has a "z-score" of 3.0

It is also possible to calculate how many
standard deviations 1.85 is from the mean
How far is 1.85 from the mean?
It is 1.85 - 1.4 = 0.45m from the mean
How many standard deviations is that? The
standard deviation is 0.15m, so:
0.45m / 0.15m = 3 standard deviations
    2/4/2012                     Dr. Riaz A. Bhutto              14
So to convert a value to a Standard Score ("z-score"):
                     •first subtract the mean,
              •then divide by the Standard Deviation
             And doing that is called "Standardizing":

  You can take any Normal Distribution and convert it to The
                Standard Normal Distribution.




2/4/2012                     Dr. Riaz A. Bhutto                15
Presentation of Data
Methods
• Tables
• Charts and Graphs
• Diagrams




2/4/2012              Dr. Riaz A. Bhutto   16
Tables
•   Simple tables
•   Frequency Distribution table
•   Cumulative Frequency table
•   Relative Frequency table




2/4/2012              Dr. Riaz A. Bhutto   17
Frequency Distribution



           Rating           Frequency
          Poor                   2
          Below Average          3
          Average                5
          Above Average          9
          Excellent              1
                      Total     20
Relative Frequency and
Percent Frequency Distributions


                       Relative     Percent
       Rating         Frequency    Frequency
      Poor                .10          10
      Below Average       .15          15
      Average             .25          25 .10(100) = 10
      Above Average       .45          45
      Excellent           .05           5
                Total    1.00         100

                                  1/20 = .05
Tabulating Numerical Data:
           Cumulative Frequency

                  Data in ordered array:
12, 13, 17, 21, 24, 24, 26, 27, 27, 30, 32, 35, 37, 38, 41, 43, 44, 46, 53, 58
                                  Cumulative           Cumulative
          Class                   Frequency            % Frequency
          10 but under 20              3                  15
          20 but under 30              9                   45
          30 but under 40             14                   70
          40 but under 50             18                  90
          50 but under 60             20                  100
Tabulating Numerical Data: Frequency
            Distributions
                                                                         (continued)

                    Data in ordered array:
  12, 13, 17, 21, 24, 24, 26, 27, 27, 30, 32, 35, 37, 38, 41, 43, 44, 46, 53, 58

                                    Relative
  Class                   Frequency Frequency Percentage
10 but under 20               3                  .15               15
20 but under 30                6                 .30                30
30 but under 40                5                 .25                25
40 but under 50               4                  .20               20
50 but under 60                2                 .10                10
Total                         20                  1                100
Charts and Graphs
 Bar Charts (for presentation of categorical
  data)
• Simple
• Multiple
• Component
 Pie Charts / graph (for presentation of
  categorical data)
 Dot frequency graphs
2/4/2012             Dr. Riaz A. Bhutto         22
Good?
                               Bar Graph
Bad?

                               Quality Ratings
               10
                9
               8
               7
   Frequency




               6
               5
               4
               3
               2
               1
                                                           Rating
                    Poor   Below Average Above Excellent
                           Average      Average
2/4/2012   Dr. Riaz A. Bhutto   24
2/4/2012   Dr. Riaz A. Bhutto   25
Pie Chart




    Most common way of presenting the categorical data. The value of each category is
    divided by the 360° and then each category is allocated the respective angles to present the
    proportion it has.

2/4/2012                                 Dr. Riaz A. Bhutto                                   26
Dot Frequency Plot
                 Tune-up Parts Cost
         .
         . .. . .                        .
     . . .. ..... .......... .. . .. . . ... . ... .
                .. .. .. ..               .
50       60     70      80        90      100   110

                             Cost (Rs.)


        Not used much anymore. Common when
           graphical drawing tools were primitive.
Diagrams
• Histogram (for presentation of continuous
  data)
• Frequency polygon
• Line diagram
• Pictogram (are a form of bar charts)
• Scatter diagram (shows the relationship
  between two variables)


2/4/2012            Dr. Riaz A. Bhutto        28
Histogram
                   Tune-up Parts Cost
            18
            16
            14
            12
Frequency




            10
             8
             6
             4
             2
                                                        Parts
                 50 59 60 69 70 79 80 89 90 99 100-110 Cost (Rs.)
Line diagram/Chart




2/4/2012           Dr. Riaz A. Bhutto   30
Pictogram




2/4/2012       Dr. Riaz A. Bhutto   31
Scatter diagram




2/4/2012          Dr. Riaz A. Bhutto   32
Scatter diagram




2/4/2012          Dr. Riaz A. Bhutto   33
THANK YOU
2/4/2012    Dr. Riaz A. Bhutto   34

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Lec bio 5

  • 1. 2/4/2012 Dr. Riaz A. Bhutto 1
  • 2. Public Health Methodologies Biostatistics 2/4/2012 Dr. Riaz A. Bhutto 2
  • 3. Ratio • is a relationship between two numbers of the same kind (e.g., objects, persons, students, spoonful s, units of whatever identical dimension) • usually expressed as "a to b" or a:b • For example, suppose I have 10 pairs of socks for every pair of shoes then the ratio of shoes:socks would be 1:10 and the ratio of socks:shoes would be 10:1 2/4/2012 Dr. Riaz A. Bhutto 3
  • 4. Coefficient of variation • Is the ratio of the standard deviation to the mean • Used to compare the relative variation or spread of the distribution of different series, samples, or population; or the different characteristics of a single series • Expressed in percentage SD CV (%) = -------- X 100 __ X 2/4/2012 Dr. Riaz A. Bhutto 4
  • 5. Example • In a medical college, the mean weight of 100 medical students is 140 lbs, with S.D of 28 lbs. The mean height of these students is 66”, with S.D of 6” • CV for weight = 28/140 x 100 = 20% CV for height = 6/66 x 100 = 9% • Based on the CV, therefore, the relative spread of weight among the students is greater than that of height 2/4/2012 Dr. Riaz A. Bhutto 5
  • 6. Percentile • Are the points which divide all measurements/value into 100 equal parts • In statistics, a percentile (or centile) is the value of a variable below which a certain percent of observations fall. • For example, the 20th percentile is the value (or score) below which 20 percent of the observations may be found. 2/4/2012 Dr. Riaz A. Bhutto 6
  • 7. • The 25th percentile is also known as the first quartile (Q1), the 50th percentile as the median or second quartile (Q2), and the 75th percentile as the third quartile (Q3). 2/4/2012 Dr. Riaz A. Bhutto 7
  • 8. Normal Distribution • Data can be "distributed" (spread out) in different ways. • It can be spread out more on the left ... or more on the right • Or it can be all jumbled up 2/4/2012 Dr. Riaz A. Bhutto 8
  • 9. A Normal Distribution But there are many cases where the data tends to be around a central value with no bias left or right, and it gets close to a "Normal Distribution" like this: The "Bell Curve" is a Normal Distribution. It is often called a "Bell Curve" because it looks like a bell. 2/4/2012 Dr. Riaz A. Bhutto 9
  • 10. Many things closely follow a Normal Distribution:  Heights of people  Size of things produced by machines  Errors in measurements  Blood pressure  Marks on a test We say the data is "normally distributed". 2/4/2012 Dr. Riaz A. Bhutto 10
  • 11. The Normal Distribution has: mean = median = mode symmetry about the center 50% of values less than the mean and 50% greater than the mean 2/4/2012 Dr. Riaz A. Bhutto 11
  • 12. 68% of values are within 1 standard deviation of the mean 95% are within 2 standard deviations 99.7% are within 3 standard deviations 2/4/2012 Dr. Riaz A. Bhutto 12
  • 13. Example: 95% of students at school are between 1.1m and 1.7m tall. Assuming this data is normally distributed can you calculate the mean and standard deviation? The mean is halfway between 1.1m and 1.7m: Mean = (1.1m + 1.7m) / 2 = 1.4m 95% is 2 standard deviations either side of the mean (a total of 4 standard deviations) so: 1 standard deviation = (1.7m-1.1m) / 4 = 0.6m / 4 = 0.15m And this is the result: It is good to know the standard deviation, because we can say that any value is: likely to be within 1 standard deviation (68 out of 100 will be) very likely to be within 2 standard deviations (95 out of 100 will be) almost certainly within 3 standard Riaz A. Bhutto (997 out of 1000 will be) 2/4/2012 Dr. deviations 13
  • 14. Standard Scores The number of standard deviations from the mean is also called the "Standard Score", "sigma" or "z-score". Get used to those words! Example: In that same school one of your friends is 1.85m tall You can see on the bell curve that 1.85m is 3 standard deviations from the mean of 1.4, so: Your friend's height has a "z-score" of 3.0 It is also possible to calculate how many standard deviations 1.85 is from the mean How far is 1.85 from the mean? It is 1.85 - 1.4 = 0.45m from the mean How many standard deviations is that? The standard deviation is 0.15m, so: 0.45m / 0.15m = 3 standard deviations 2/4/2012 Dr. Riaz A. Bhutto 14
  • 15. So to convert a value to a Standard Score ("z-score"): •first subtract the mean, •then divide by the Standard Deviation And doing that is called "Standardizing": You can take any Normal Distribution and convert it to The Standard Normal Distribution. 2/4/2012 Dr. Riaz A. Bhutto 15
  • 16. Presentation of Data Methods • Tables • Charts and Graphs • Diagrams 2/4/2012 Dr. Riaz A. Bhutto 16
  • 17. Tables • Simple tables • Frequency Distribution table • Cumulative Frequency table • Relative Frequency table 2/4/2012 Dr. Riaz A. Bhutto 17
  • 18. Frequency Distribution Rating Frequency Poor 2 Below Average 3 Average 5 Above Average 9 Excellent 1 Total 20
  • 19. Relative Frequency and Percent Frequency Distributions Relative Percent Rating Frequency Frequency Poor .10 10 Below Average .15 15 Average .25 25 .10(100) = 10 Above Average .45 45 Excellent .05 5 Total 1.00 100 1/20 = .05
  • 20. Tabulating Numerical Data: Cumulative Frequency Data in ordered array: 12, 13, 17, 21, 24, 24, 26, 27, 27, 30, 32, 35, 37, 38, 41, 43, 44, 46, 53, 58 Cumulative Cumulative Class Frequency % Frequency 10 but under 20 3 15 20 but under 30 9 45 30 but under 40 14 70 40 but under 50 18 90 50 but under 60 20 100
  • 21. Tabulating Numerical Data: Frequency Distributions (continued) Data in ordered array: 12, 13, 17, 21, 24, 24, 26, 27, 27, 30, 32, 35, 37, 38, 41, 43, 44, 46, 53, 58 Relative Class Frequency Frequency Percentage 10 but under 20 3 .15 15 20 but under 30 6 .30 30 30 but under 40 5 .25 25 40 but under 50 4 .20 20 50 but under 60 2 .10 10 Total 20 1 100
  • 22. Charts and Graphs  Bar Charts (for presentation of categorical data) • Simple • Multiple • Component  Pie Charts / graph (for presentation of categorical data)  Dot frequency graphs 2/4/2012 Dr. Riaz A. Bhutto 22
  • 23. Good? Bar Graph Bad? Quality Ratings 10 9 8 7 Frequency 6 5 4 3 2 1 Rating Poor Below Average Above Excellent Average Average
  • 24. 2/4/2012 Dr. Riaz A. Bhutto 24
  • 25. 2/4/2012 Dr. Riaz A. Bhutto 25
  • 26. Pie Chart Most common way of presenting the categorical data. The value of each category is divided by the 360° and then each category is allocated the respective angles to present the proportion it has. 2/4/2012 Dr. Riaz A. Bhutto 26
  • 27. Dot Frequency Plot Tune-up Parts Cost . . .. . . . . . .. ..... .......... .. . .. . . ... . ... . .. .. .. .. . 50 60 70 80 90 100 110 Cost (Rs.) Not used much anymore. Common when graphical drawing tools were primitive.
  • 28. Diagrams • Histogram (for presentation of continuous data) • Frequency polygon • Line diagram • Pictogram (are a form of bar charts) • Scatter diagram (shows the relationship between two variables) 2/4/2012 Dr. Riaz A. Bhutto 28
  • 29. Histogram Tune-up Parts Cost 18 16 14 12 Frequency 10 8 6 4 2 Parts 50 59 60 69 70 79 80 89 90 99 100-110 Cost (Rs.)
  • 30. Line diagram/Chart 2/4/2012 Dr. Riaz A. Bhutto 30
  • 31. Pictogram 2/4/2012 Dr. Riaz A. Bhutto 31
  • 32. Scatter diagram 2/4/2012 Dr. Riaz A. Bhutto 32
  • 33. Scatter diagram 2/4/2012 Dr. Riaz A. Bhutto 33
  • 34. THANK YOU 2/4/2012 Dr. Riaz A. Bhutto 34