2. Definition of Bioprocessing
A bioprocess can be explained as a particular process that utilises
complete living cells or some of their cellular components to get
3. Definition of Bioprocessing
The process is used in the creation of nourishments, pharmaceuticals,
flavours, energy and synthetic concoctions with the guide of a
biocatalyst. A catalyst in bioprocessing can be microorganisms, plants
or creature cells in a bioreactor.
4. Definition of Bioprocessing
Alongside, it includes hereditary designing for the control of animals,
plants and microorganisms. Downstream handling is required to expel
debasements, mass volume decrease and concurrent convergence of
the ideal item from the bioreactor.
5. Upstream and Downstream Process in
Cell treatment bioprocessing is an order that combines the fields of cell
treatment and bioprocessing. Cell treatment bioprocessing aims to
build up reproducible and sturdy manufacturing procedures to produce
6. Upstream and Downstream Process in
Commercially significant bioprocesses can:
• Generate items to keep up the entirety of the quality gauges of
• It can also offer clinical and industrial measures of remedial cells all
through different phases of improvement.
• Control the expense of merchandise (CoGs) of the last medication
7. Upstream Bioprocessing
Bioprocessing hardware incorporates a wide range of gear for explicit
capacities and applications. In extensive terms and as for a procedure
stream graph, the hardware can be categorised in three categories:
Upstream gear manages the development of a host life form to deliver
a product. The product may be simply the living beings, it might be held
inward to the creature, or it may be discharged into the development
8. Downstream Bioprocessing
Downstream bioprocessing explains the part from the upstream where
the cell mass is handled to meet virtue and quality prerequisites. It is
typically partitioned into three primary areas: cell interruption, a
decontamination segment and a cleaning segment.
9. Downstream Bioprocessing
The means of downstream preparing are:
1. Insolubles are Removed
• Gravity settling
26. Significance of Bioprocessing
• The Environment
Many environmental problems will require bioprocess
eg.- minimization of manufacturing waste, treatment of
municipal waste, environmentally friendly manufacturing
28. Significance of Bioprocessing
DEFENSE AND NATIONAL SECURITY
The Department of Defense (DOD) and Department of Energy face enormous
problems in cleanup of military bases as they are closed or moth-balled and in
cleanup of weapons laboratories. In the former, biological methods might play
an important part.
29. Significance of Bioprocessing
DEFENSE AND NATIONAL SECURITY
• Chemical and Biological Warfare
A continuing problem in DOD concerns chemical and biological warfare. The
stated U.S. position is to be prepared in a defensive mode, but not to be
involved in production of biological weapons. The importance of either
chemical or biological agents as practical weapons systems remains to be
30. Reference Book
Chapter 6 The Future | Putting Biotechnology to Work: Bioprocess
Engineering | The National Academies Press
Notes de l'éditeur
if biologically produced materials (surfactants and viscosifiers) are used in enhanced oil recovery and in transportation of heavy crudes and coal slurries, appropriate biological manufacturing facilities must be developed.
Bioprocess engineering in agriculture and the food industry involves the application of biocatalysts (living cells or their components) to produce useful and value-added products, and it offers opportunities to design and produce new or improved agricultural and food products and their manufacturing processes.
Basic research in plant molecular biology has allowed the clonal production of plants through the process of somatic embryogenesis, in which somatic cells develop through the stages of embryogenesis to yield whole plants without gamete fusion.