1. GENETIC EPIDEMIOLOGY
OF SARS-COV-2:
INSIGHTS FROM
MULTIPLE STUDIES
Presented by:
Darakhshan Irfan

2. Introduction
• SARS-CoV-2 a novel coronavirus was first identified in
December 2019 in Wuhan, Hubei Province, China.
• Genetic Epidemiology is the study of contribution of
genetic factor in health or disease in family and population
and how genes interplay with environmental factors
• Phylogenetic analysis is a key tool in genetic
epidemiology that allows researchers to reconstruct the
evolutionary relationships among different SARS-CoV-2
strains and track the spread of the virus

3. Problem Statement
• SARS-CoV-2 has spread globally, leading to a pandemic
• Which resulted in millions of infections and deaths
worldwide, significantly impacting healthcare systems,
economies, and daily life.
• it's crucial to understand its transmission dynamics and
genetic diversity in controlling its spread and developing
effective interventions.

4. Objectives
• To examine the genetic diversity, evolutionary relationship,
and transmission of virus.
• This study may aid in controlling viral spread. It
emphasizes how important phylogenetics is for
understanding the genetic epidemiology of SARS-CoV-2
and how it could influence clinical and public health
decisions.

5. Methodology
• Data Collection
• Sample Preparation
• Next Generation Sequencing
• Data Analysis
• Phylogenetic Analysis

6. Results

9. Conclusions
• In conclusion, the studies highlight the important role that
phylogenetic analysis plays in the genetic epidemiology of
SARS-CoV-2.
• Phylogenetic analysis can provide valuable insights into
the transmission dynamics and spread of SARS-CoV-2,
including the identification of local transmission clusters
and the tracking of viral evolution over time and
complementing traditional epidemiological methods