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YELLOWYELLOW
FEVERFEVER
SUJATA MOHAPATRA.SUJATA MOHAPATRA.
OUTLINEOUTLINE
 IntroductionIntroduction
 Disease BackgroundDisease Background
 DistributionDistribution
 Epidemiology...
Disease BackgroundDisease Background
 First account ofFirst account of
sickness diagnosed assickness diagnosed as
YF occu...
Global DistributionGlobal Distribution
 In 45 countries ofIn 45 countries of
Africa & LatinAfrica & Latin
America.America...
EPIDEMIOLOGYEPIDEMIOLOGY
Flavivirus FibricusFlavivirus Fibricus
ManMan
Forest(>24Forest(>2400
))
YELLOW
FEVER
AgentAgent
 Flavivirus FibricusFlavivirus Fibricus
 Group B ArbovirusGroup B Arbovirus
Reservoir & VectorReservoir & Vector
 MonkeyMonkey
 MosquitoMosquito
Host FactorHost Factor
 All ages & both sexesAll ages & both sexes
 Persons in contact withPersons in contact with
fores...
The SEVIR ModelThe SEVIR Model
Humans can be in one of five categories at a time.
*Virus incubating*Virus incubating
**Con...
Environmental FactorEnvironmental Factor
 ClimateClimate
 Tropical with a relativeTropical with a relative
humidity.humi...
INCUBATION PERIODINCUBATION PERIOD –– 3-6 days3-6 days
PERIOD OF COMMUNICABILITYPERIOD OF COMMUNICABILITY -- Blood ofBlood...
Cycles of YFCycles of YF
TransmissionTransmission
MOSQUITO
MONKE
Y
HUMAN,
MONKE
Y
MOSQUIT
O
HUMAN HUMAN
MOSQUIT
O
MOSQUITO...
Clinical featuresClinical features
Diagnosis &Diagnosis &
ManagementManagement
 Blood studiesBlood studies
 Supportive TreatmentSupportive Treatment
 IV F...
Prevention & ControlPrevention & Control
 17D17D Vaccine,Vaccine,
 SubcutaneouslySubcutaneously 0.5ml0.5ml,,
 Immunity ...
Yellow fever
Yellow fever
Yellow fever
Yellow fever
Yellow fever
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Yellow fever

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Yellow fever

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Yellow fever

  1. 1. YELLOWYELLOW FEVERFEVER SUJATA MOHAPATRA.SUJATA MOHAPATRA.
  2. 2. OUTLINEOUTLINE  IntroductionIntroduction  Disease BackgroundDisease Background  DistributionDistribution  EpidemiologyEpidemiology  TransmissionTransmission  Diagnosis & managementDiagnosis & management  Prevention and ControlPrevention and Control  Actions to TakeActions to Take
  3. 3. Disease BackgroundDisease Background  First account ofFirst account of sickness diagnosed assickness diagnosed as YF occurred in 1648.YF occurred in 1648.  Causative agent:Causative agent: genus Flavivirus.genus Flavivirus.  Vector: Aedes aegyptiVector: Aedes aegypti (mosquito).(mosquito).  Nonhuman primatesNonhuman primates maintain disease.maintain disease.
  4. 4. Global DistributionGlobal Distribution  In 45 countries ofIn 45 countries of Africa & LatinAfrica & Latin America.America.  More than 900 millionMore than 900 million people are at risk.people are at risk.  200,000 cases &200,000 cases & 30,000 deaths30,000 deaths worldwide each year.worldwide each year.
  5. 5. EPIDEMIOLOGYEPIDEMIOLOGY Flavivirus FibricusFlavivirus Fibricus ManMan Forest(>24Forest(>2400 )) YELLOW FEVER
  6. 6. AgentAgent  Flavivirus FibricusFlavivirus Fibricus  Group B ArbovirusGroup B Arbovirus
  7. 7. Reservoir & VectorReservoir & Vector  MonkeyMonkey  MosquitoMosquito
  8. 8. Host FactorHost Factor  All ages & both sexesAll ages & both sexes  Persons in contact withPersons in contact with forests.forests.  Wood cutters, Hunters.Wood cutters, Hunters.  Immunity-Immunity- One attack ofOne attack of yellow fever givesyellow fever gives lifelonglifelong immunity.immunity.
  9. 9. The SEVIR ModelThe SEVIR Model Humans can be in one of five categories at a time. *Virus incubating*Virus incubating **Contagious**Contagious ***Includes: survivors, victims, Immune***Includes: survivors, victims, Immune Susceptible Exposed* Infective** Recovered*** Vaccinated
  10. 10. Environmental FactorEnvironmental Factor  ClimateClimate  Tropical with a relativeTropical with a relative humidity.humidity.  Endemic presence ofEndemic presence of disease in the jungle.disease in the jungle.  Social FactorsSocial Factors  Urbanization,Urbanization,  More Populated,More Populated,  Forest.Forest.
  11. 11. INCUBATION PERIODINCUBATION PERIOD –– 3-6 days3-6 days PERIOD OF COMMUNICABILITYPERIOD OF COMMUNICABILITY -- Blood ofBlood of patients is infective during the first 3-4days.patients is infective during the first 3-4days.
  12. 12. Cycles of YFCycles of YF TransmissionTransmission MOSQUITO MONKE Y HUMAN, MONKE Y MOSQUIT O HUMAN HUMAN MOSQUIT O MOSQUITO MOSQUIT O MOSQUITO Jungle Village City www.who.int
  13. 13. Clinical featuresClinical features
  14. 14. Diagnosis &Diagnosis & ManagementManagement  Blood studiesBlood studies  Supportive TreatmentSupportive Treatment  IV FluidsIV Fluids  AntipyreticsAntipyretics  AntibioticsAntibiotics  Use of Mosquito-net orUse of Mosquito-net or mosquito repellents.mosquito repellents.
  15. 15. Prevention & ControlPrevention & Control  17D17D Vaccine,Vaccine,  SubcutaneouslySubcutaneously 0.5ml0.5ml,,  Immunity begins to appear on theImmunity begins to appear on the77thth day & lasts for more thanday & lasts for more than 35 years35 years..  International Certificates.International Certificates.

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