World renowned invited speaker - Mark Crowell's power-point slides as presented at the May 28th event!

2. Accelerating the CommercializationAccelerating the Commercialization
of Researchof Research
W. Mark Crowell
Executive Director, UVa Innovation
Associate Vice President for Research
© Copyright 2013 by UVa Innovation
Idaho Coalition for Innovation

3. Greetings from Charlottesville / UVaGreetings from Charlottesville / UVa
Innovation is in our DNA:Innovation is in our DNA:
““Whenever an invention proves to be useful, itWhenever an invention proves to be useful, it
ought to be tried.”ought to be tried.” (TJ)(TJ)
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Shared heritage between
Charlottesville and Idaho –
Lewis & Clark Expedition (TJ)

4. Setting the StageSetting the Stage
Role of Universities in enhancing innovation-basedRole of Universities in enhancing innovation-based
economic developmenteconomic development
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5. Funding, market, political and otherFunding, market, political and other
realities facing universities and TTOsrealities facing universities and TTOs
 ~85% of US TTO revenue made by 30 institutions; more
than ½ do NOT break even
 Rate of growth in federal R&D funding is flattening
 Faculty / talent recruitment and TTOs
 Industry and venture capital moving “upstream” (and
not returning); technology gap is widening
 Universities increasingly being asked to help drive
economy… product developers, economic developers,
global health experts, collaboration managers, revenue
generators, investors, management recruiters….
 University supporters – including donors and elected
officials – have innovation at top of their agendas

6. “Somebody has to do something, and it’s
just incredibly pathetic that it has to be
us.” (Garcia)
Societal need… or mandateSocietal need… or mandate
“Science serving humanity…” (Jefferson)
“In America, innovation isn’t
just how we change
our lives; it’s how we make a
living.” (Obama)

7. The Way We WereThe Way We Were
Patent-Centric Technology LicensingPatent-Centric Technology Licensing
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UVa Tech Transfer – “Before”UVa Tech Transfer – “Before”
Oversimplified illustration of traditional technology transfer model

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10. Tech Transfer 2.0 at UVaTech Transfer 2.0 at UVa
Innovating the Way We Do BusinessInnovating the Way We Do Business
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11. The catalyst for change: Coulter TranslationalThe catalyst for change: Coulter Translational
PartnershipPartnership
 BME faculty/clinician pairing required
 Very active oversight board
 $1M/year for 5 years; about $100K/project per year
 U.Va. 1 of 9 universities in 5-year experiment; 1 of 6 to receive
$10M endowment (required 1:1 match)
 Results:
 > 30 projects funded; 5 startups; 11 licenses; > $12 million in
venture capital and private investments; > $20 million in federal,
state or foundation grants
 About half of disclosures licensed within 2 years
 Externally audited 7:1 ROI for whole portfolio
 Top 10% of projects > 40:1 ROI

12. National Coulter Program Outcomes - @ 5National Coulter Program Outcomes - @ 5
yearsyears Number of
projects
US$ (in millions)
Funded projects 200 40
Projects at animal
efficacy or first in human
100+
VC Funding 28 152.9
Industry Licenses 24
Start-ups in Formation 17 5+
Governmental Project
Specific Funding
150+
Total Commercial
Relevance Events
69 308+
Follow-on Investment = $308M / $40M > 7x
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13. U.Va.’s translational / proof-of-concept programsU.Va.’s translational / proof-of-concept programs
 ~$5M/year into translational work
 Sourced from a variety of partners (Corporate, Foundation,
Individual Donors)
 Coulter Foundation Translational Partnership
 LaunchPad Fund in Diabetes Biomedical Innovation
 Cardiovascular/AstraZeneca Collaboration
 Ivy Foundation/Johnson & Johnson – COSAT
 i6 / Department of Commerce / Virginia Innovation Partnership
 Partnering with venture philanthropy organizations
 Enhanced disclosure, patent, and deal flow
 Established administrative frame-work/best-practices
 Plug-and-play in disease settings
 Robust faculty engagement in culture of translational research
and innovation

14. A new innovation agenda at UVaA new innovation agenda at UVa
 New position – Chief Innovation Officer (UVa Innovation) –
signals commitment of UVa to accelerate translation of
innovation for economic and social benefit
 Dissatisfaction with prior focus on patenting; protecting;
driving revenue; misalignment w/ research agenda
 Serve as UVa’s “front door” for innovation, commercial &
investment partners, and for economic development
 Promote culture change within the institution –
innovation / commercialization valued more highly, taught
more widely, practiced more robustly
 Grow UVa’s innovation ecosystem (entrepreneurship,
accelerator, seed funding, mentors, awards, etc.) –
internally and externally
 Raise the institution’s “partnering IQ”

15.  Renewed emphasis on proof-of-concept, market-facing
research
 Moving from culture of invention to culture of
innovation (from technology push to market pull)
 Addressing risk, adding value, creating impact –
translating good ideas into enterprise
 Connecting and partnering across silos, disciplines,
campuses, regions, and the world (authentic
partnering)
 Announcing that we’re “open for business”
 Leveraging intellectual assets university-wide to
create/deliver value – and to solve real problems
 University backed the budget!!!
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Adopting a Culture of InnovationAdopting a Culture of Innovation

16.  Rebranded UVa Patent Foundation to UVa
Licensing and Ventures Group (LVG)
 Revise business and revenue sharing models
 Shift focus from patents to deals/partnerships
– from technology push to market pull
 Connect UVa Innovation across Va., US, world
 Establish UVa Innovation brand – tie together
tech transfer, entrepreneurship, innovation,
corporate partnering across Grounds
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11stst
18 months – Build the platform:18 months – Build the platform:

17. Executive Director,
UVa Innovation
Entrepreneurial
Networks Group
Licensing and
Ventures Group
Strategic
Partnerships
Group
Communications
Group
UVa-wide
Innovation
Initiatives
Translational
Research
Initiatives
UVa Venture
Summit
Vice President for
Research
Accelerator and
Seed Fund
Initiatives
UVa E*Cup and
Business Plan
Competitions
Innovation
Education
UVa Innovation
Platform / “O” Chart

18.  Formerly the U.Va. Patent Foundation
 Name change reflects shifting emphasis from IP to
commercialization pathways
 Goals
 Dissemination of U.Va. knowledge/assets
 Value-added business development activity
 High levels of customer service
 Quality transactions
U.Va. Licensing & Ventures GroupU.Va. Licensing & Ventures Group
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19. Creating, facilitating and empowering
entrepreneurial networks among the University’s
faculty, staff, students, alumni and the community
Venture Forward mentoring network, events
Economic development
Community involvement
Student entrepreneurship and competitions
Entrepreneurial NetworksEntrepreneurial Networks
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20. Facilitating internal and external partnerships and
collaborations with industry, foundations, federal
agencies, philanthropists and investors
Proof-of-concept / translational research funding
 VIP, Coulter, Ivy, Swortzel, Launchpad
Public–private partnerships
 AstraZeneca, ATCC, Rolls-Royce, Cancer Center
Technology Partnership Initiative
Strategic PartnershipsStrategic Partnerships
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21. Elevating the profile of University innovators,
ventures, partners and initiatives through strategic
public and media relations
Corporate communications
Branding
Website, blog, social media
Press releases, media relations, spokesperson
Event marketing and collateral
Marketing & CommunicationsMarketing & Communications
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UVa Innovation: Bringing Together NewUVa Innovation: Bringing Together New
and Existing Initiatives (& strategies)and Existing Initiatives (& strategies)
…Others brewing!
Socialmedia
Venture m
entorsEntrepreneur-in-
Residence
Business Concept
Com
petitions
Crowdfunding
VenturePhilanthropy

23. Other new pan-university innovationOther new pan-university innovation
initiativesinitiatives
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 Multiple business concept
competitions
 Supporting, co-branding
innovation initiative
across Grounds and Cville
 Expanded presence at
trade shows and scientific
meetings
 Recruit major innovation
events to Virginia
 UVa Venture Summit
 Virginia Innovation
Partnership – i6 Award
 UVa startup company
survey
 Aggressive engagement –
UVa Innovation on radar
regionally, nationally,
internationally
 CROWDFUNDING!!!
(www.virginia.edu/useed)

24. A personal look back…. to RTPA personal look back…. to RTP
What does impact look like?What does impact look like?
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25. Impact of university innovation:Impact of university innovation:
RTP pre- and post-technology transferRTP pre- and post-technology transfer
 1989 (1st
30 years) – Real estate focus. 60 firms; 30,000
employees; most firms mid to large sized (era of little to
modest university tech transfer)
 2002 (next 13 years) – 150+ R&D firms; 45,000+
employees; 52% of firms have less than 10 employees;
86% have less than 250 employees (era of major
university tech transfer)
 1500+ start-ups since 1980; 34% of current companies
are start-ups

26. 1959 - RTP launched; what does1959 - RTP launched; what does
growth look like at 50 years old?growth look like at 50 years old?

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U.Va. Innovation Mobile SiteU.Va. Innovation Mobile Site

34. Simplified, Increased TransparencySimplified, Increased Transparency
 Learning Center
 Educational primers
 Templates
 Streamlined
disclosure forms
 In progress
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http://innovation.virginia.edu/learning-center

35. Demonstrating ImpactDemonstrating Impact
 Product pipeline
 Research reagent
directory
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http://innovation.virginia.edu/impact/products

36. U.Va. Innovation VenturesU.Va. Innovation Ventures
 Launched interactive
map and directory
 Venture survey
currently in progress,
gathering:
 Vitals
 Economic development
metrics
 Testimonials:
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http://innovation.virginia.edu/impact/ventures

37. Accelerating the CommercializationAccelerating the Commercialization
of Researchof Research
W. Mark Crowell
Executive Director, UVa Innovation
Associate Vice President for Reserach
© Copyright 2013 by UVa Innovation
Idaho Coalition for Innovation

38. Sponsors
Silver Bronze