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II BIOSENSOR PRINCIPLE APPLICATIONS AND WORKING II

agpharmacy11

Poster to be presented at Stochastic Numerics and Statistical Learning: Theory and Applications Workshop 2024, Kaust, Saudi Arabia, https://cemse.kaust.edu.sa/stochnum/events/event/snsl-workshop-2024. In this work we have considered a setting that mimics the Henry problem \cite{Simpson2003,Simpson04_Henry}, modeling seawater intrusion into a 2D coastal aquifer. The pure water recharge from the ``land side'' resists the salinisation of the aquifer due to the influx of saline water through the ``sea side'', thereby achieving some equilibrium in the salt concentration. In our setting, following \cite{GRILLO2010}, we consider a fracture on the sea side that significantly increases the permeability of the porous medium. The flow and transport essentially depend on the geological parameters of the porous medium, including the fracture. We investigated the effects of various uncertainties on saltwater intrusion. We assumed uncertainties in the fracture width, the porosity of the bulk medium, its permeability and the pure water recharge from the land side. The porosity and permeability were modeled by random fields, the recharge by a random but periodic intensity and the thickness by a random variable. We calculated the mean and variance of the salt mass fraction, which is also uncertain. The main question we investigated in this work was how well the MLMC method can be used to compute statistics of different QoIs. We found that the answer depends on the choice of the QoI. First, not every QoI requires a hierarchy of meshes and MLMC. Second, MLMC requires stable convergence rates for $\EXP{g_{\ell} - g_{\ell-1}}$ and $\Var{g_{\ell} - g_{\ell-1}}$. These rates should be independent of $\ell$. If these convergence rates vary for different $\ell$, then it will be hard to estimate $L$ and $m_{\ell}$, and MLMC will either not work or be suboptimal. We were not able to get stable convergence rates for all levels $\ell=1,\ldots,5$ when the QoI was an integral as in \eqref{eq:integral_box}. We found that for $\ell=1,\ldots 4$ and $\ell=5$ the rate $\alpha$ was different. Further investigation is needed to find the reason for this. Another difficulty is the dependence on time, i.e. the number of levels $L$ and the number of sums $m_{\ell}$ depend on $t$. At the beginning the variability is small, then it increases, and after the process of mixing salt and fresh water has stopped, the variance decreases again. The number of random samples required at each level was estimated by calculating the decay of the variances and the computational cost for each level. These estimates depend on the minimisation function in the MLMC algorithm. To achieve the efficiency of the MLMC approach presented in this work, it is essential that the complexity of the numerical solution of each random realisation is proportional to the number of grid vertices on the grid levels.

$Poster_density_driven_with_fracture_MLMC.pdf$ $Poster_density_driven_with_fracture_MLMC.pdf$

Poster_density_driven_with_fracture_MLMC.pdf

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Photos from our Spring Gala 2024. Thank you for making our 2024 Spring Gala unforgettable! Whether you attended or supported us with a donation, we extend our heartfelt thanks for celebrating School-Community Partnerships alongside ExpandED Schools. Special appreciation to our honorees, Rachel Skaistis and Cravath, Swaine, & Moore LLP, for their unwavering support in advancing educational equity. Your contributions have profoundly impacted countless young New Yorkers, and we’re proud to have you as part of our community. Our gratitude also extends to our Board of Directors, sponsors, city partners, community-based organizations, and the inspiring young people who joined us. Your support fuels our mission, and we’re endlessly thankful for your dedication. While we celebrate our gala’s success, our work continues. As you view the evening’s highlights, consider how you can further empower young New Yorkers and educators with your donation, no matter the size. Donate today: https://www.expandedschools.org/support-our-work/donate/

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The Department of Emergency Medicine at Carolinas Medical Center is passionate about education! Dr. Michael Gibbs is a world-renowned clinician and educator and has helped guide numerous young clinicians on the long path of Mastery of Emergency Medical Care. With his oversight, the EMGuideWire team aim to help augment our understanding of emergent imaging. You can follow along with the EMGuideWire.com team as they post these educational, self-guided radiology slides or you can also use this section to learn more in-depth about specific conditions and diseases. This Radiology Reading Room pertains to Ventriculoperitoneal Shunts and their Complications and is brought to you by Brandon Friedman, MD, Kelsey Patterson, and L. Erin Miller MD. It is has special guest editor: Scott Wait, MD

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II BIOSENSOR PRINCIPLE APPLICATIONS AND WORKING II

$Poster_density_driven_with_fracture_MLMC.pdf$ $Poster_density_driven_with_fracture_MLMC.pdf$

Poster_density_driven_with_fracture_MLMC.pdf

Chapter 7 Pharmacosy Traditional System of Medicine & Ayurvedic Preparations ...

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