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Chapter 2
                               Drug Use as a Social
                                    Problem

© 2009 McGraw-Hill Higher Education. All rights reserved.
Costs of Drug Use to Society

                       Deaths
                       Emergency room visits
                       Drugs in the workplace and lost productivity
                       Broken homes, illnesses, shorter lives, etc.
                       Cost of maintaining habit
                       Cost of criminal behavior
                       Cost of treating patients
                       Fetal alcohol syndrome
                       Others?
© 2009 McGraw-Hill Higher Education. All rights reserved.
Changing Attitudes

          What made the government change
           from the laissez-faire attitude of the
           1800s to one of control?
                    Toxicity
                    Dependence
                    Crime




© 2009 McGraw-Hill Higher Education. All rights reserved.
Toxicity

            Toxic = poisonous, deadly, or dangerous
          What makes a drug toxic?
                    Amount used
                    How it is used
                    What the user did while on the drug



© 2009 McGraw-Hill Higher Education. All rights reserved.
Toxicity

          Physiological toxicity vs. behavioral toxicity
          Acute effects vs. chronic effects




      Acute behavioral toxicity (drunk driving)                  Chronic physiological toxicity (cirrhosis)

© 2009 McGraw-Hill Higher Education. All rights reserved.
Drug-Related Toxicity

         Examples of acute toxicity
          Behavioral: “Intoxication” that impairs the
           actions of drug users and increases the
           danger to themselves and others
          Physiological: Overdose that causes the
           user to stop breathing



© 2009 McGraw-Hill Higher Education. All rights reserved.
Drug-Related Toxicity
         Examples of chronic toxicity
          Behavioral
                    Personality and lifestyle changes
                    Effects on relationships with friends and family
          Physiological
                         Heart disease
                         Lung cancer
                         Cirrhosis
                         Other health effects


© 2009 McGraw-Hill Higher Education. All rights reserved.
© 2009 McGraw-Hill Higher Education. All rights reserved.
Drug Abuse Warning Network

          A system for collecting data on drug-
           related deaths and emergency room visits
           at some U.S. metropolitan hospitals
          DAWN collects data on
           improper use of legal
           prescription and over-
           the-counter drugs as
           well as illicit drugs
© 2009 McGraw-Hill Higher Education. All rights reserved.
Drug Abuse Warning Network

          Alcohol is reported only
           in combination with other
           drugs
          Drug-alcohol and drug-
           drug combinations are
           very common



© 2009 McGraw-Hill Higher Education. All rights reserved.
D.A.W.N. Toxicity Data




© 2009 McGraw-Hill Higher Education. All rights reserved.
Drug Abuse Warning Network
                                     Toxicity Data
         ER Visits                                          Deaths
         1. Cocaine                                         1. Prescription Opioids
         2. Alcohol-in-                                        (not heroin)
            combination                                     2. Cocaine
         3. Marijuana                                       3. Alcohol-in-
         4. Prescription Opioids                               combination
         5. Benzodiazepines                                 4. Benzodiazepines
                                                            5. Methadone

© 2009 McGraw-Hill Higher Education. All rights reserved.
Drug Abuse Warning Network
          What it tells us about how dangerous a
           drug is
                    Simply gives us total deaths/ER visits
          What it does not tell us about how
           dangerous a drug is
                    Consider relative danger vs. total impact of
                     the drug
                    Number of users vs. number of reported
                     problems

© 2009 McGraw-Hill Higher Education. All rights reserved.
Blood-Borne Diseases

          Specific toxicity for users who inject drugs
          AIDS, HIV infection, and hepatitis B and C
          Sharing needles passes infectious agents
           directly into the bloodstream
                    Some states, cities prohibit
                   needle purchase without Rx
                    Syringe exchange programs


© 2009 McGraw-Hill Higher Education. All rights reserved.
Substance Dependence
          What do “addicts” look like?
          What drug do they take or what behavior do they
           engage in (alcohol, cigarettes, illicit drugs, food,
           sex, gambling, shopping, computer time)?
          How much time do they spend on their habit?
          How much of a drug do they take?
          How do you decide on the definition of
           dependence?



© 2009 McGraw-Hill Higher Education. All rights reserved.
Substance Dependence

          Three basic
           processes
                    Tolerance
                    Physical
                     dependence
                    Psychological
                     dependence



© 2009 McGraw-Hill Higher Education. All rights reserved.
Tolerance

          Diminished effect on the body after
           repeated use of the same drug
          The body develops ways to compensate
           for the chemical imbalance caused by the
           drug
          Regular drug users may build up tolerance
           to the extent that their dosage would kill a
           novice user
© 2009 McGraw-Hill Higher Education. All rights reserved.
Physical Dependence
          Physical dependence is defined by the
           occurrence of a withdrawal syndrome
          Tolerance typically precedes physical
           dependence
          If drug use is stopped suddenly,
           withdrawal symptoms occur, ranging from
           mild to severe
          Physical dependence means the body has
           adapted to the drug’s presence
© 2009 McGraw-Hill Higher Education. All rights reserved.
Psychological Dependence
          Psychological or
           behavioral dependence
                    High frequency of drug use
                    Craving for the drug
                    Tendency to relapse after
                     stopping use
          Behavior is reinforced by
           the consequences
                    Over time, this becomes the
                     biggest reason users report
                     they continue to use
© 2009 McGraw-Hill Higher Education. All rights reserved.
Changing Views of
                                                          Dependence
          Early medical model = true addiction involves
           physical dependence; key is treatment of withdrawal
           symptoms
          Positive reinforcement model = drugs can reinforce
           behavior without physical dependence
          Psychological dependence is increasingly viewed as
           the driving force behind repeated drug use
                    This refutes the sometimes common belief that drugs that
                     aren’t as strongly physically addicting are less dangerous



© 2009 McGraw-Hill Higher Education. All rights reserved.
Substance Abuse and
                                      Dependence: DSM-IV-TR
          APA diagnostic criteria for abuse and
           dependence (Table on page 36)
          Complex behavioral definitions
          Dependence can occur with or without
           physiological dependence (i.e., withdrawal)




© 2009 McGraw-Hill Higher Education. All rights reserved.
Substance Dependence:
                                               DSM-IV-TR
          A maladaptive pattern of substance use leading to clinically significant
           impairment or distress, as manifested by three (or more) of the following,
           occurring at any time in the same 12-month period:
             1. Tolerance
             2. Withdrawal
             3. Substance often taken in larger amounts or over a period longer than
                intended
             4. Persistent desire or unsuccessful efforts to cut down or control substance
                use
             5. A great deal of time is spent in obtaining the substance
             6. Important social, occupational, or recreational activities are given up or
                reduced because of substance use
             7. Substance use continues despite knowledge of having a persistent or
                recurrent problem that is caused or exacerbated by the substance

© 2009 McGraw-Hill Higher Education. All rights reserved.
Substance Abuse:
                                                          DSM-IV-TR
          A maladaptive pattern of substance use leading to
           clinically significant impairment or distress, as
           manifested by one or more of the following occurring at
           any time in the same 12-month period:
                   1. Recurrent substance use resulting in failure to fulfill major role
                      obligations at work, school, or home
                   2. Recurrent substance use in situations in which it is physically
                      hazardous
                   3. Recurrent substance-related legal problems
                   4. Continued substance use despite having persistent or
                      recurrent social or interpersonal problems caused or
                      exacerbated by the effects of the substance


© 2009 McGraw-Hill Higher Education. All rights reserved.
Is Dependence
                        Caused by the Substance?
          Some drugs are more likely
           than others to lead to
           dependence
          Method of use, as well as
           other factors, influences risk
           of dependence
          The “war on drugs” reflects
                                      .
           the perspective that drugs are
           themselves evil

© 2009 McGraw-Hill Higher Education. All rights reserved.
Table 2.3: Dependence Potential of
                      Psychoactive Drugs




© 2009 McGraw-Hill Higher Education. All rights reserved.
Is Dependence Biological?

          Is dependence due to biochemical or
           physiological actions in the brain?
          Still no way to scan the brain and know if a
           person has/had developed dependence
                    Genetic physiological or biochemical markers
                     have been sought as well, but none has
                     proven reliable



© 2009 McGraw-Hill Higher Education. All rights reserved.
Is There an “Addictive
                                           Personality”?
          No way to know if the drug or the drug use
           changes a person’s personality
          Many other factors affect personality
          Sensation-seeking = a personality
           characteristic statistically associated with
           early substance use and abuse



© 2009 McGraw-Hill Higher Education. All rights reserved.
Is Dependence a Family
                                      Disorder?
          Alcohol dependence
           often exists within a
           dysfunctional family
          Evidence suggests that
           dysfunctional
           relationships play a role
           in dependence, but they
           aren’t the only factor

© 2009 McGraw-Hill Higher Education. All rights reserved.
Is Substance Dependence a
                              Disease?
          Founders of AA characterized alcohol
           dependence as a disease
          Others argue that dependence doesn’t
           have all the characteristics of a disease
                    There are ways to test and treat the effects of
                     alcoholism but not the disease itself
                    There is some disagreement over how to
                     define disease as well

© 2009 McGraw-Hill Higher Education. All rights reserved.
Biopsychosocial Perspective

          Dependence is related to
           dysfunctions of:
                    Biology
                    Personality
                    Social interactions




© 2009 McGraw-Hill Higher Education. All rights reserved.
Drugs and Crime
     Drug use may change a
      person’s personality
     People under the
      influence may commit
      crimes (e.g., many cases
      of homicide, domestic
      violence, etc.)


© 2009 McGraw-Hill Higher Education. All rights reserved.
Drugs and Crime

                 Crimes may be
                  carried out to obtain
                  money for drugs
                 Drug use is a crime




© 2009 McGraw-Hill Higher Education. All rights reserved.
Why We Regulate Drugs

          We want to protect society from the
           dangers of some types of drug use =
           legitimate social purpose
          Some laws are not developed as part of a
           rationally devised plan and may not be
           realistic or effective
                    Current laws: How did we get to these?
                     - assignment

© 2009 McGraw-Hill Higher Education. All rights reserved.
Chapter 2

                                  Drug Use as a Social Problem
                                         ??????????



© 2009 McGraw-Hill Higher Education. All rights reserved.

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Chptr 2 Drug Use as a Social Problem

  • 1. Chapter 2 Drug Use as a Social Problem © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 2. Costs of Drug Use to Society  Deaths  Emergency room visits  Drugs in the workplace and lost productivity  Broken homes, illnesses, shorter lives, etc.  Cost of maintaining habit  Cost of criminal behavior  Cost of treating patients  Fetal alcohol syndrome  Others? © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 3. Changing Attitudes  What made the government change from the laissez-faire attitude of the 1800s to one of control?  Toxicity  Dependence  Crime © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 4. Toxicity Toxic = poisonous, deadly, or dangerous  What makes a drug toxic?  Amount used  How it is used  What the user did while on the drug © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 5. Toxicity  Physiological toxicity vs. behavioral toxicity  Acute effects vs. chronic effects Acute behavioral toxicity (drunk driving) Chronic physiological toxicity (cirrhosis) © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 6. Drug-Related Toxicity Examples of acute toxicity  Behavioral: “Intoxication” that impairs the actions of drug users and increases the danger to themselves and others  Physiological: Overdose that causes the user to stop breathing © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 7. Drug-Related Toxicity Examples of chronic toxicity  Behavioral  Personality and lifestyle changes  Effects on relationships with friends and family  Physiological  Heart disease  Lung cancer  Cirrhosis  Other health effects © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 8. © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 9. Drug Abuse Warning Network  A system for collecting data on drug- related deaths and emergency room visits at some U.S. metropolitan hospitals  DAWN collects data on improper use of legal prescription and over- the-counter drugs as well as illicit drugs © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 10. Drug Abuse Warning Network  Alcohol is reported only in combination with other drugs  Drug-alcohol and drug- drug combinations are very common © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 11. D.A.W.N. Toxicity Data © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 12. Drug Abuse Warning Network Toxicity Data ER Visits Deaths 1. Cocaine 1. Prescription Opioids 2. Alcohol-in- (not heroin) combination 2. Cocaine 3. Marijuana 3. Alcohol-in- 4. Prescription Opioids combination 5. Benzodiazepines 4. Benzodiazepines 5. Methadone © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 13. Drug Abuse Warning Network  What it tells us about how dangerous a drug is  Simply gives us total deaths/ER visits  What it does not tell us about how dangerous a drug is  Consider relative danger vs. total impact of the drug  Number of users vs. number of reported problems © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 14. Blood-Borne Diseases  Specific toxicity for users who inject drugs  AIDS, HIV infection, and hepatitis B and C  Sharing needles passes infectious agents directly into the bloodstream  Some states, cities prohibit needle purchase without Rx  Syringe exchange programs © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 15. Substance Dependence  What do “addicts” look like?  What drug do they take or what behavior do they engage in (alcohol, cigarettes, illicit drugs, food, sex, gambling, shopping, computer time)?  How much time do they spend on their habit?  How much of a drug do they take?  How do you decide on the definition of dependence? © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 16. Substance Dependence  Three basic processes  Tolerance  Physical dependence  Psychological dependence © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 17. Tolerance  Diminished effect on the body after repeated use of the same drug  The body develops ways to compensate for the chemical imbalance caused by the drug  Regular drug users may build up tolerance to the extent that their dosage would kill a novice user © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 18. Physical Dependence  Physical dependence is defined by the occurrence of a withdrawal syndrome  Tolerance typically precedes physical dependence  If drug use is stopped suddenly, withdrawal symptoms occur, ranging from mild to severe  Physical dependence means the body has adapted to the drug’s presence © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 19. Psychological Dependence  Psychological or behavioral dependence  High frequency of drug use  Craving for the drug  Tendency to relapse after stopping use  Behavior is reinforced by the consequences  Over time, this becomes the biggest reason users report they continue to use © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 20. Changing Views of Dependence  Early medical model = true addiction involves physical dependence; key is treatment of withdrawal symptoms  Positive reinforcement model = drugs can reinforce behavior without physical dependence  Psychological dependence is increasingly viewed as the driving force behind repeated drug use  This refutes the sometimes common belief that drugs that aren’t as strongly physically addicting are less dangerous © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 21. Substance Abuse and Dependence: DSM-IV-TR  APA diagnostic criteria for abuse and dependence (Table on page 36)  Complex behavioral definitions  Dependence can occur with or without physiological dependence (i.e., withdrawal) © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 22. Substance Dependence: DSM-IV-TR  A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by three (or more) of the following, occurring at any time in the same 12-month period: 1. Tolerance 2. Withdrawal 3. Substance often taken in larger amounts or over a period longer than intended 4. Persistent desire or unsuccessful efforts to cut down or control substance use 5. A great deal of time is spent in obtaining the substance 6. Important social, occupational, or recreational activities are given up or reduced because of substance use 7. Substance use continues despite knowledge of having a persistent or recurrent problem that is caused or exacerbated by the substance © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 23. Substance Abuse: DSM-IV-TR  A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by one or more of the following occurring at any time in the same 12-month period: 1. Recurrent substance use resulting in failure to fulfill major role obligations at work, school, or home 2. Recurrent substance use in situations in which it is physically hazardous 3. Recurrent substance-related legal problems 4. Continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 24. Is Dependence Caused by the Substance?  Some drugs are more likely than others to lead to dependence  Method of use, as well as other factors, influences risk of dependence  The “war on drugs” reflects . the perspective that drugs are themselves evil © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 25. Table 2.3: Dependence Potential of Psychoactive Drugs © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 26. Is Dependence Biological?  Is dependence due to biochemical or physiological actions in the brain?  Still no way to scan the brain and know if a person has/had developed dependence  Genetic physiological or biochemical markers have been sought as well, but none has proven reliable © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 27. Is There an “Addictive Personality”?  No way to know if the drug or the drug use changes a person’s personality  Many other factors affect personality  Sensation-seeking = a personality characteristic statistically associated with early substance use and abuse © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 28. Is Dependence a Family Disorder?  Alcohol dependence often exists within a dysfunctional family  Evidence suggests that dysfunctional relationships play a role in dependence, but they aren’t the only factor © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 29. Is Substance Dependence a Disease?  Founders of AA characterized alcohol dependence as a disease  Others argue that dependence doesn’t have all the characteristics of a disease  There are ways to test and treat the effects of alcoholism but not the disease itself  There is some disagreement over how to define disease as well © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 30. Biopsychosocial Perspective  Dependence is related to dysfunctions of:  Biology  Personality  Social interactions © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 31. Drugs and Crime  Drug use may change a person’s personality  People under the influence may commit crimes (e.g., many cases of homicide, domestic violence, etc.) © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 32. Drugs and Crime  Crimes may be carried out to obtain money for drugs  Drug use is a crime © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 33. Why We Regulate Drugs  We want to protect society from the dangers of some types of drug use = legitimate social purpose  Some laws are not developed as part of a rationally devised plan and may not be realistic or effective  Current laws: How did we get to these? - assignment © 2009 McGraw-Hill Higher Education. All rights reserved.
  • 34. Chapter 2 Drug Use as a Social Problem ?????????? © 2009 McGraw-Hill Higher Education. All rights reserved.