Presented By : Lodha Sakshi Mahendra
Roll no : 31
Class : T.Y B.Pharmacy
Assig. Topic : Types of capsules
Guided by : Mrs. N.S.Baste Mam
SNJB’S SSDJ COLLEGE OF PHARMACY ,
CHANDWAD.
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TYPES OF CAPSULE :-
1. Hard Gelatin Capsule
2. Soft Gelatin Capsule
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik)
CAPSULES💊
Hard capsules
Soft Capsules
1. HARD GELATIN CAPSULES :-
• The hard gelatin capsule consists of two pieces in the
form of cylinders closed at one end.
• The shorter piece is called the cap. This cap fits over the
open end of longer piece called body.
• Hard gelatin capsules are also known as dry-filled
capsules or two piece capsules.
• This capsules are used in extemporaneous
compounding of Rx.
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• This capsules are made up of gelatin , sugar and water.
• HGC are tasteless.
• Colour with various FD & C and D & C dyes.
• They made opaque by addition of Titanium Dioxide.
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•Manufacturing of Hard gelatin capsules :-
Steps involved in making empty gelatin capsules :
1.Dipping
2.Spinning
3.Drying
4.Stripping
5.Trimming
6.Joining
7.Polishing
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•ADVANTAGES OF HGC :-
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1. Capsules are tasteless, odorless.
2. Combination of powders we can use.
3. They are attractive in appearance.
4. They can be filled quickly and conveniently.
5. They are economical.
6. They are easy to handle and carry.
7. Easy to swallow.
8. Physician can change the dose and
combination of drug according to patient
requirement.
• DISADVANTAGE OF HGC :-
1. Capsules are not suitable for liquids that dissolve
gelatin, such as aqueous or hydro alcoholic solutions.
2. The concentrated solutions which require previous
dilution are unsuitable for capsules because if
administered as such lead to irritation into stomach.
3. Not useful for efflorescent or deliquescent materials.
4. Efflorescent cause capsules to soften & Deliquescent
may dry the capsule shell to brittleness.
5. More expensive.
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2. SOFT GELATIN CAPSULE :-
• Soft Gelatin capsules are one piece, hermetically
sealed, soft gelatin shells containing a liquid, a
suspension, or a semisolid.
• Soft gelatin is mainly composed of gelatin, plasticizers,
preservative, colouring and opacifying agents, flavoring
agents and sugars.
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• Manufacturing process of soft gelatin
capsule :-
Methods for manufacturing of SGC :-
1. Plate – process
2. Rotary die method
3. Norton capsule machine
4. Accogel capsule machine
5. Globex method
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• ADVANTAGES OF SGC :-
1. They are easy to administer.
2. Easy to manufacture.
3. Liquid can be encapsulated.
4. Small to large sizes possible.
5. Elegance
6. Portability
7. Odour & taste masking
8. Ready availability of drug hence gives fast action.
• DISADVANTAGES OF SGC :-
1. Water soluble material & are difficult to incorporate.
2. Highly moisture sensitive.
3. Efflorescent material can be incorporated , they may
cause softening.
4. Deliquescent material not used.
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• APPLICATIONS OF SGC :-
1. Wate immisable, volatile & non-volatile liq. such as
vegetable & aromatic oils,aromatic & aliphatic
hydrocarbon , Chlorinated hydrocarbon, ether, ester,
alcohol.
2. Water miscible non volatile liq. Such as polyethylene
glycol, nonionic surface active agent as poly sorbate
80.
3. Water miscible & relatively non vol.Compounds
4. As a suppository dosage form.
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Difference between SGC &
HGC
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