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Clinical Case 3

A 53-year-old women comes to see you for a consultation. She is scheduled to take a caribbean cruise in 2 weeks but is concerned about sea sickness. She has been on boats before and is very sensitive to motion sickness. A friend mentioned to her that there is a patch that is effective for this problem. She is in good health and takes no medications regularly. Her examination is normal. You prescribe a scopolamine transdermal patch for her.

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Clinical Case 3

  1. 1.  A 53-year-old women comes to see you for a consultation. She is scheduled to take a caribbean cruise in 2 weeks but is concerned about sea sickness. She has been on boats before and is very sensitive to motion sickness. A friend mentioned to her that there is a patch that is effective for this problem. She is in good health and takes no medications regularly. Her examination is normal. You prescribe a scopolamine transdermal patch for her.
  2. 2. Questions 1. What is the mechanism of action of scopolamine? 2. What are the common side effects of this medication? 3. What are some relative contraindications to its use?
  3. 3. Summary  A 53-year-old woman with motion sickness is prescribed transdermal scopolamine before she takes a sea cruise.
  4. 4. Mechanism of action of scopolamine  Competitive antagonist of muscarinic cholinoreceptors in the vestibular system and the CNS
  5. 5. Common side effects  Mydriasis  Dry mouth  Tachycardia  Urinary retention  Confusion  Drowsiness
  6. 6. Relative contraindications  Glaucoma  Urinary obstruction  Heart disease

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