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Open Drug Discovery Teams

http://molmatinf.com/oddt.html



                                                  Dr. Alex M. Clark
                                                  Dr. Sean Ekins
                                                  May 2012
                                                  Montréal NewTech


   © 2012 Molecular Materials Informatics, Inc.
        and Collaborations in Chemistry
                                 1
The Problem
$           •   Drug discovery research is very asymmetric.

            •   Diseases with many wealthy sufferers get
                most of the attention: great return on
                investment.




                                                              #
    •   Rare diseases? Neglected markets?

    •   Resources are extremely tight.

    •   Cannot afford not to share research.
The Solution
• government      funding   • academics        publication
• pharma                    • startups
• charity                   • independents


                                             • literature
Open Drug Discovery Teams
                                             • blogs
                              Twitter
                                             • open science
• content
    aggregation
•   research                     #hashtags
    communities
The App
                                     •   iPhone, iPod, iPad

                                     •   Free!
                                         bit.ly/JHsfhz




#sanfilipposyndrome   #tuberculosis       #leishmaniasis
#greenchemistry      #hivaids            #huntingtons
#malaria             #chagas             #H5N1
Topic Browsing
                                             •     Magazine-like

                                             •     Thumbnails

                                             •     Links

                                             •     Molecules

                                             •     Voting



•   Users curate the relevant content by endorsing

•   Interaction is done by tweeting from the app

•   The result is a crowd-curated knowledge resource
The Business Model
•       App is free, data is totally open

•       Funding options:
    -     Charitable donations, e.g. Kickstarter
    -     Research grants, e.g. Gates fund
    -     Sponsorship, e.g. per-topic donations
    -     Advertising to a well targeted audience

•       Adding additional value to data and selling subscriptions

•       Significant new intellectual property, can be licensed for
        internal use
More Information

http://molmatinf.com/oddt.html
http://cheminf20.org
http://collabchem.com



                                                  @aclarkxyz
                                                  @collabchem

   © 2012 Molecular Materials Informatics, Inc.
        and Collaborations in Chemistry
                                 7

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Montreal NewTech: Open Drug Discovery Teams

  • 1. Open Drug Discovery Teams http://molmatinf.com/oddt.html Dr. Alex M. Clark Dr. Sean Ekins May 2012 Montréal NewTech © 2012 Molecular Materials Informatics, Inc. and Collaborations in Chemistry 1
  • 2. The Problem $ • Drug discovery research is very asymmetric. • Diseases with many wealthy sufferers get most of the attention: great return on investment. # • Rare diseases? Neglected markets? • Resources are extremely tight. • Cannot afford not to share research.
  • 3. The Solution • government funding • academics publication • pharma • startups • charity • independents • literature Open Drug Discovery Teams • blogs Twitter • open science • content aggregation • research #hashtags communities
  • 4. The App • iPhone, iPod, iPad • Free! bit.ly/JHsfhz #sanfilipposyndrome #tuberculosis #leishmaniasis #greenchemistry #hivaids #huntingtons #malaria #chagas #H5N1
  • 5. Topic Browsing • Magazine-like • Thumbnails • Links • Molecules • Voting • Users curate the relevant content by endorsing • Interaction is done by tweeting from the app • The result is a crowd-curated knowledge resource
  • 6. The Business Model • App is free, data is totally open • Funding options: - Charitable donations, e.g. Kickstarter - Research grants, e.g. Gates fund - Sponsorship, e.g. per-topic donations - Advertising to a well targeted audience • Adding additional value to data and selling subscriptions • Significant new intellectual property, can be licensed for internal use
  • 7. More Information http://molmatinf.com/oddt.html http://cheminf20.org http://collabchem.com @aclarkxyz @collabchem © 2012 Molecular Materials Informatics, Inc. and Collaborations in Chemistry 7