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PHYSIOLOGY OF THE GASTROINTESTINAL TRACT (GIT) Main function: The GIT provides the body with a supply of water, nutrients, electrolytes, vitamines. Actions: 1) Digestion of the food 2) Absorption of the products of digestion Ad 1) Digestive processes: - mechanical - chemical Mechanical methods: - mastication (chewing) - swallowing (deglutition) - movements of the GIT (motor functions) Chemical means (secretions): - saliva - gastric juice - pancreatic juice - intestinal juice - bile PHYSIOLOGY OF MOUTH Functions: 1/ Mechanical and chemical digestion of the food 2/ The source of the unconditioned reflexes 3/ Control of physical and chemical properties of the food Ad 1 a Mechanical activity – mastication The anterior teeth – a cutting action The posterior teeth – a grinding action Thee maximal closing force - incissors 15 kg - mollars 50 kg Inervations of the muscles of chewing – 5th, 8th, 12th cranial nerves Centers – near the brain stem and cerebral cortex centers for taste Act of mastication: The movement of the lower jaw down: - Contraction of m. biventer mandibulae (m.digastricus), m. pterygoideus ext., m.m. infrahyoidei → The movement – up: the drop initiates a stretch reflex Contraction of m. masseter, m. temporalis, m. pterygoideus Rebound of antagonists- inhibition – the jaw drops + compression of the bolus of the food against the linings of the mouth - rebound – repetitive actions..... Mastication reflexive and voluntary Function of the mastication: - grinding the food - mixing with saliva - prevention of excoriation of GIT - makes easy swalowing 2 - aids subsequent digestion SALIVATION Ad 1 b) Adjustment of the food by the saliva The salivary glands: - parotid - submandibular - sublingual - buccal Secretion of the saliva: - basal - 800 – 1500 ml/day - during intake of food Regulation of salivary secretion – nervous - parasympathetic - sympathetic Unconditioned reflexes: Taste and tactile stimuli increase 8-20 times the basal rate of secretion Conditioned reflexes: Visual, olphactoric, acoustic stimuli Centers: salivatory nuclei (at the juncture of the medulla and pons): superior – submandibular (70%), sublingual (5%) inferior – parotid (serous saliva). The gastrointestinal system consists of the gastrointestinal tract and the accessory exocrine glands. The gastrointestinal tract includes the mouth, the esophagus, the stomach, the small intestine, and the large intestine. The major accessory glands are the salivary glands, the liver, the gallbladder, and the pancreas. The major functions of the gastrointestinal system are assimilation of nutrients and excretion of waste products via the biliary system. Movement of food through the gastrointestinal system (motility) is carefully coordinated with the delivery of appropriate fluid and enzyme solutions (secretion) so that the macromolecules in food can be hydrolyzed (digestion) and the nutrient molecules, which are liberated, can be transported into the circulatory.
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