This document provides an overview of blockchain, big data, artificial intelligence (AI), and internet of things (IoT) technologies and their integration. It discusses the components and use cases of each technology individually. It then explores how blockchain can be integrated with big data, AI, and IoT to address challenges around data volume, velocity, variety and veracity. The document also introduces Xanadu, a scalable distributed file system, and how it can enable more efficient blockchain + big data + AI + IoT integration through its functionality like deduplication, replication, and high throughput/low latency data access and querying.