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Drug redistribution Example the onset of anaesthesia with thiopenta.pdf

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Drug redistribution Example: the onset of anaesthesia with thiopental is instantaneous and the duration is ultra-short. The quick onset and brief duration of thiopental reflect the rapidity by which this drug equilibrate the blood and the central nervous system (CNS) Soon after a peak brain concentration is reached, the concentration begins to fall as thiopental continue to be redistributed to muscles and fat leading to termination of anaesthesia..

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Drug redistribution Example: the onset of anaesthesia with thiopental is instantaneous and the duration is ultra-short. The quick onset and brief duration of thiopental reflect the rapidity by which this drug equilibrate the blood and the central nervous system (CNS) Soon after a peak brain concentration is reached, the concentration begins to fall as thiopental continue to be redistributed to muscles and fat leading to termination of anaesthesia.

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Drug redistribution Example the onset of anaesthesia with thiopenta.pdf

  • 1. Drug redistribution Example: the onset of anaesthesia with thiopental is instantaneous and the duration is ultra-short. The quick onset and brief duration of thiopental reflect the rapidity by which this drug equilibrate the blood and the central nervous system (CNS) Soon after a peak brain concentration is reached, the concentration begins to fall as thiopental continue to be redistributed to muscles and fat leading to termination of anaesthesia.