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ADRENAL CORTEX AND MEDULLA
 
ADRENAL MEDULLA AND CORTEX ,[object Object],[object Object]
Adrenal  cortex
Adrenal Steroid Hormones ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Structures of adrenal steroids ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
 
Regulation of adrenal steroids ,[object Object],[object Object]
Regulation of adrenal steroids ,[object Object],[object Object],[object Object]
 
REGULATION OF GLUCOCORTICOIDS ,[object Object],[object Object],[object Object],[object Object],[object Object]
Diurnal pattern of cortisol
Summary of actions of adrenal steroids ,[object Object],[object Object],[object Object],[object Object]
Actions of Glucocorticoids  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Metabolic effects of cortisol ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anti-inflammatory and –immune effects of cortisol ,[object Object],[object Object],[object Object],[object Object]
More actions of cortisol ,[object Object],[object Object],[object Object],[object Object]
Relative potencies of drugs and dangers ,[object Object],[object Object],[object Object],[object Object],[object Object]
Actions of aldosterone ,[object Object],[object Object]
Action of aldosterone on kidney
Regulation of aldosterone Secretion ,[object Object],[object Object],[object Object],[object Object]
 
Zona Glomerulosa: Disorders ,[object Object],[object Object],[object Object]
Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
  Hyperadrenalism: Cushing’s Syndrome  Hyper secretion of cortisol 1.Independent of ACTH i.e GC excess with low ACTH  Causes :Treatment with Gcs Tumor  of Ad cortex  2. ACTH dependent ( Cushing Disease )  GC excess with increased ACTH  Causes :- Tumor in Pituitary, lungs, kidneys, or pancreas  Treatment with ACTH
 
Cushing’s Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Adrenal medulla
Adrenal medulla ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adrenal medulla
 
 
Stress ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Responses to Stress
Life-Span Changes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phaeochromocytoma ,[object Object],[object Object]
PANCREAS
Pancreas ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Hormones of the pancreas ,[object Object],[object Object],[object Object],[object Object]
INSULIN
 
Actions of Insulin ,[object Object],[object Object],[object Object]
 
Insulin decreases blood fatty acid and ketoacid concentrations.  ,[object Object],[object Object],[object Object]
Insulin decreases blood amino acid concentration ,[object Object],[object Object]
Other actions of insulin ,[object Object],[object Object],[object Object]
 
Summary of major actions of insulin: ANABOLIC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Insulin control  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Insulin Disorders: Diabetes Mellitus ,[object Object],[object Object]
Signs and symptoms  ,[object Object],[object Object],[object Object],[object Object]
Continued ….. ,[object Object],[object Object],[object Object]
Diagnostic criteria
Type I Diabetes Mellitus  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Type II Diabetes Mellitus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Risk Factors for Type 2 Diabetes Age > 40 Family history of diabetes Ethnicity  Obesity; abdominal fat distribution GDM, or infant > 9 lbs Hypertension, hyperlipidemia Previous Impaired Glucose Tolerance
GLUCAGON
Glucagon ,[object Object],[object Object]
Regulation of Glucagon Secretion ,[object Object],[object Object]
Effects of glucagon
  Factors Affecting Glucagon Secretion ,[object Object],[object Object]
 
Major actions of glucagon ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pancreatic somatostatin
Pancreatic somatostatin ,[object Object],[object Object],[object Object],[object Object],[object Object]
Paracrine interactions
Pancreatic polypeptide
Pancreatic polypeptide ,[object Object],[object Object],[object Object],[object Object],[object Object]
“ Secondary” Endocrine Organs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Adrenal, pancreas[1]