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Digestion  is the breakdown
 of large, complex organic
 molecules into smaller
 components that can be
 used by the body.
Molecules need to be small
 enough to diffuse across
 plasma membranes.
Steps of digestion
   Ingestion – this is the consumption of or taking in
    of nutrients.
   Digestion – the chemical breakdown of large
    organic molecules into smaller components by
    enzymes.
   Absorption – the transport or delivery of
    digested nutrients to body tissues.
   Assimilation-the conversion of absorbed food
    into the substance of the body.
   Egestion – the elimination of food waste
    materials from the body.
Esophagus
Approximately 10” long
Functions include:
1.Secrete mucus
2.Moves food from the throat to
the stomach using muscle
movement called peristalsis
If acid from the stomach gets in
here that’s heartburn.
STOMACH
J-shaped muscular bag that stores the
food you eat, breaks it down into tiny
pieces.
Mixes food with digestive juices that
contain enzymes to break down
proteins and lipids.
Acid in the stomach kills bacteria.
Food found in the stomach is called
chyme.
Small intestines are roughly
7 meters long
Lining of intestine walls has
finger-like projections
called villi, to increase
surface area.
The villi are covered in
microvilli which further
increases surface area for
absorption.
SMALL INTESTINE
The majority of chemical
digestion occurs in the first
of three sections of the
small intestine known as the
duodenum.
This section also contains an
opening from the bile duct
and pancreatic duct through
which bile and pancreatic
enzymes enter the small
intestine
Small Intestine
             Food enters the small
              intestine as a semi-
              solid mixture known as
              chyme. The chyme is
              acidic due to the HCl in
              the stomach so it
              needs to be
              neutralized.
             The presence of chyme
              in the small intestine
              triggers the conversion
              of prosecretin into
              secretin which is
              absorbed into the blood
              stream and carried to
              the pancreas
Large intestine

About 5 feet long
Accepts what small
intestines don’t absorb
Rectum (short term
storage which holds
feces before it is
expelled).
ANUS
 Thehuman anus is the
 external opening of the
 rectum.Its closure is controlled
 by sphincter muscles. Feces are
 expelled from the body through
 the anus during the act of
 defecation, the primary
 function of the anus.
Accessory Organs

•    Salivary gland
•   Liver
•    gall bladder
•    pancreas
Salivary glands

  parotid glands - produce a
  serous, watery secretion.


  submaxillary (mandibular)
  glands - produce a mixed
  serous and mucous secretion.


  sublingual glands - secrete a
  saliva that is predominantly
  mucous in character.
Liver
           The liver is a large
            accessory organ of the
            digestive system that is
            constantly producing a
            fluid known as bile.
           Bile is stored in the gall
            bladder until it is needed
            in the small intestine.
Liver and Gall Bladder

   The presence of lipids in the
    small intestine trigger the
    release of the hormone
    cholecystokinin (CCK) which
    triggers the release of bile
    from the gall bladder.
   Bile contains bile salts that
    emulsifies fats which means it
    breaks them into smaller
    droplets so they can be
    digested.
Pancreas

              The pancreas is an accessory
               organ of the digestive
               system. It releases
               chemicals to aid in
               digestion.
              Secretin will stimulate the
               pancreas to release a
               solution containing
               bicarbonate ion into the
               small intestine where it will
               neutralize the acidic chyme
               and raise the pH from 2.5 to
               9.0. This inactivates the
               pepsin.
Pancreas and Carbohydrates

                     Amylase enzymes are
                      released from the
                      pancreas that break large
                      carbohydrate chains into
                      small chains called
                      disaccharides.
                     Then the small intestine
                      releases disaccharide
                      enzymes which break
                      those small chains into
                      individual sugars.
Pancreas & Proteins

   Trypsinogen, a protein-
    digesting enzyme is released
    into the small intestine where
    it is convertes into trypsin and
    it breaks down large protein
    chains into smaller chains.
   The final step in protein
    digestion occurs with the
    release of erepsins from the
    pancreas and they break the
    smaller chains into individual
    amino acids.
ABSORPTION OF MATERIAL
The passage of digested food from the digestive tract into
the tissue or into the blood and lymph is called
abosrption.
Structure of the Villus
   Each villus contains a
    capillary network along
    with a lacteal.
   End products of protein
    and carbohydrate
    digestion enter the
    capillary network.
   End products of fat
    digestion are absorbed
    into the lacteal. The
    lacteal is a vessel of the
    lymphatic system.
THANK
    YOU

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Physiology of the digestive system

  • 1.
  • 2. Digestion is the breakdown of large, complex organic molecules into smaller components that can be used by the body. Molecules need to be small enough to diffuse across plasma membranes.
  • 3.
  • 4.
  • 5. Steps of digestion  Ingestion – this is the consumption of or taking in of nutrients.  Digestion – the chemical breakdown of large organic molecules into smaller components by enzymes.  Absorption – the transport or delivery of digested nutrients to body tissues.  Assimilation-the conversion of absorbed food into the substance of the body.  Egestion – the elimination of food waste materials from the body.
  • 6.
  • 7. Esophagus Approximately 10” long Functions include: 1.Secrete mucus 2.Moves food from the throat to the stomach using muscle movement called peristalsis If acid from the stomach gets in here that’s heartburn.
  • 8.
  • 9.
  • 10. STOMACH J-shaped muscular bag that stores the food you eat, breaks it down into tiny pieces. Mixes food with digestive juices that contain enzymes to break down proteins and lipids. Acid in the stomach kills bacteria. Food found in the stomach is called chyme.
  • 11.
  • 12. Small intestines are roughly 7 meters long Lining of intestine walls has finger-like projections called villi, to increase surface area. The villi are covered in microvilli which further increases surface area for absorption.
  • 13. SMALL INTESTINE The majority of chemical digestion occurs in the first of three sections of the small intestine known as the duodenum. This section also contains an opening from the bile duct and pancreatic duct through which bile and pancreatic enzymes enter the small intestine
  • 14. Small Intestine  Food enters the small intestine as a semi- solid mixture known as chyme. The chyme is acidic due to the HCl in the stomach so it needs to be neutralized.  The presence of chyme in the small intestine triggers the conversion of prosecretin into secretin which is absorbed into the blood stream and carried to the pancreas
  • 15. Large intestine About 5 feet long Accepts what small intestines don’t absorb Rectum (short term storage which holds feces before it is expelled).
  • 16. ANUS  Thehuman anus is the external opening of the rectum.Its closure is controlled by sphincter muscles. Feces are expelled from the body through the anus during the act of defecation, the primary function of the anus.
  • 17. Accessory Organs • Salivary gland • Liver • gall bladder • pancreas
  • 18. Salivary glands parotid glands - produce a serous, watery secretion. submaxillary (mandibular) glands - produce a mixed serous and mucous secretion. sublingual glands - secrete a saliva that is predominantly mucous in character.
  • 19. Liver  The liver is a large accessory organ of the digestive system that is constantly producing a fluid known as bile.  Bile is stored in the gall bladder until it is needed in the small intestine.
  • 20. Liver and Gall Bladder  The presence of lipids in the small intestine trigger the release of the hormone cholecystokinin (CCK) which triggers the release of bile from the gall bladder.  Bile contains bile salts that emulsifies fats which means it breaks them into smaller droplets so they can be digested.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25. Pancreas  The pancreas is an accessory organ of the digestive system. It releases chemicals to aid in digestion.  Secretin will stimulate the pancreas to release a solution containing bicarbonate ion into the small intestine where it will neutralize the acidic chyme and raise the pH from 2.5 to 9.0. This inactivates the pepsin.
  • 26. Pancreas and Carbohydrates  Amylase enzymes are released from the pancreas that break large carbohydrate chains into small chains called disaccharides.  Then the small intestine releases disaccharide enzymes which break those small chains into individual sugars.
  • 27. Pancreas & Proteins  Trypsinogen, a protein- digesting enzyme is released into the small intestine where it is convertes into trypsin and it breaks down large protein chains into smaller chains.  The final step in protein digestion occurs with the release of erepsins from the pancreas and they break the smaller chains into individual amino acids.
  • 28.
  • 29.
  • 30. ABSORPTION OF MATERIAL The passage of digested food from the digestive tract into the tissue or into the blood and lymph is called abosrption.
  • 31. Structure of the Villus  Each villus contains a capillary network along with a lacteal.  End products of protein and carbohydrate digestion enter the capillary network.  End products of fat digestion are absorbed into the lacteal. The lacteal is a vessel of the lymphatic system.
  • 32.
  • 33.
  • 34.
  • 35. THANK YOU