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Organiza%onal	
  
                     facts,	
  metrics	
  and	
  
                       characteris%cs	
  




                                                       Prac%%oner	
  	
  	
  	
  
Best	
  available	
  scien%fic	
                     exper%se,	
  reflec%on	
  
                                                                                    Evidence-­‐based	
  
          evidence	
                                  and	
  judgement	
                decision	
  




                    Stakeholders’	
  values	
  
                       and	
  concerns	
  
Peptic ulcer – an infectious disease!

This year's Nobel Prize in Physiology or Medicine goes to Barry Marshall and Robin
Warren, who with tenacity and a prepared mind challenged prevailing dogmas. By
using technologies generally available (fibre endoscopy, silver staining of
histological sections and culture techniques for microaerophilic bacteria), they
made an irrefutable case that the bacterium Helicobacter pylori is causing disease.
By culturing the bacteria they made them amenable to scientific study.


In 1982, when this bacterium was discovered by Marshall and Warren, stress and
lifestyle were considered the major causes of peptic ulcer disease. It is now

firmly established that Helicobacter pylori
causes more then 90% of duodenal ulcers.
The   link    between   Helicobacter   pylori
infection and peptic ulcer disease has been
established   through   studies   of   human
volunteers, antibiotic treatment studies and
epidemiological studies.
Clinicians’ clinical
                expertise




Evidence                          Decision




               Patients’
           preferences and
             clinical state
=
A   It is shown that …


            B           It is likely that …


        C
                                     There are signs
                                     that …
    D
                                     Experts are of the
-                                    opinion that …
Organiza%onal	
  
                     facts,	
  metrics	
  and	
  
                       characteris%cs	
  




                                                       Prac%%oner	
  	
  	
  	
  
Best	
  available	
  scien%fic	
                     exper%se,	
  reflec%on	
  
                                                                                    Evidence-­‐based	
  
          evidence	
                                  and	
  judgement	
                decision	
  




                    Stakeholders’	
  values	
  
                       and	
  concerns	
  
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction
Evidence-Based Management, an introduction

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Evidence-Based Management, an introduction

  • 1.
  • 2.
  • 3.
  • 4. Organiza%onal   facts,  metrics  and   characteris%cs   Prac%%oner         Best  available  scien%fic   exper%se,  reflec%on   Evidence-­‐based   evidence   and  judgement   decision   Stakeholders’  values   and  concerns  
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10. Peptic ulcer – an infectious disease! This year's Nobel Prize in Physiology or Medicine goes to Barry Marshall and Robin Warren, who with tenacity and a prepared mind challenged prevailing dogmas. By using technologies generally available (fibre endoscopy, silver staining of histological sections and culture techniques for microaerophilic bacteria), they made an irrefutable case that the bacterium Helicobacter pylori is causing disease. By culturing the bacteria they made them amenable to scientific study. In 1982, when this bacterium was discovered by Marshall and Warren, stress and lifestyle were considered the major causes of peptic ulcer disease. It is now firmly established that Helicobacter pylori causes more then 90% of duodenal ulcers. The link between Helicobacter pylori infection and peptic ulcer disease has been established through studies of human volunteers, antibiotic treatment studies and epidemiological studies.
  • 11.
  • 12.
  • 13.
  • 14. Clinicians’ clinical expertise Evidence Decision Patients’ preferences and clinical state
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
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  • 41.
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49. =
  • 50.
  • 51. A It is shown that … B It is likely that … C There are signs that … D Experts are of the - opinion that …
  • 52.
  • 53.
  • 54.
  • 55.
  • 56. Organiza%onal   facts,  metrics  and   characteris%cs   Prac%%oner         Best  available  scien%fic   exper%se,  reflec%on   Evidence-­‐based   evidence   and  judgement   decision   Stakeholders’  values   and  concerns