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International Conference on
                           Non-Ionizing Radiation and Children’s Health




             Session 5 – Risk management and Prevention
                              Discussion


                                                 Mirjana Moser



                                         LJubljana, 18-20 Mai 2011


NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                      1
Are our children today
                              sufficiently protected against
                                           NIR?




NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101           2
Are our children today sufficiently protected against NIR?
  Evidence
       What is the level of evidence for particular, children related, risks from NIR?
       What level of evidence do a risk manager need?

  High exposures, technology development
       Which are critical / high exposures?
       What technology development should we follow in order to anticipate potential future
        risks for children

  Research need
       What are research priorities?

  Measures
       What protection, precaution measures are feasible and “reasonable”?
       What measures have been taken?
       What measures should be taken?
NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                                           3
Static Electric and Magnetic fields

 Evidence
  Some data on pregnancy and occupational exposures up to ~ 2T
  ??? effects for stronger fields

 High exposures, technology development
  MRI - occupational exposure of pregnant women

 Research need
  Effects of static fields > 3T

 Measures
 
  revision of occupational exposure directive?




NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                              4
ELF EMF
   Evidence
    childhood leukaemia (might be multistage, multifactor effect)
    risk for brain cancer (some suggestions)?
    no effect on development (animal studies)

   High exposures (> 0.4 μT), technology development
    power lines
    household installations and appliances (floor heating, transformers, electric blankets,
     waterbeds..)
    transportation

   Research need
    interdisciplinary research on leukaemia (genetic, animal, epi, different agents)
     like research programm in Germany (BfS)
    big, worldwide prospective studies?
    mechanisms (new ideas like radical pair mechanism – RPM)?

   Measures
    precautionary measures mostly considering power lines
    precautionary measures for other appliances (no waterbeds for children)?
    recommendations or more strict regulations (limits, restrictions)?
NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                                           5
Intermediate frequencies EMF

    Evidence
     ???
    

    High exposures, technology development
     induction cooker
     RFID, EAS
     energy saving lamps
     wireless power transfer

    Research need
     research need in all disciplines!!
    

    Measures
    
     research programm covering all disciplines


NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                                  6
HF-EMF
 Evidence
  brain cancer (CEFALO –in publication, Mobi-Kids starting), no increase in cancer incidence
  well-being, cognition, behaviour - some indications, but methodological problems; lifestyle
 influence,
   day-time sleepiness because of sending SMS during night
  development, teratological effects (animal studies) – no effects
  changes in EEG (human)?
  animal studies on: brain structure and function – no effect, blood-brain barrier – some effects

 High exposures, technology development
  mobile phones
  emerging (telecommunication) technologies? change in exposures? change of lifestyle?

 Research need
  interaction mechanisms (gene expression, mechanistic tumour promoters)
  exposures and dosimetry of new technologies
  prospective epidemiological studies
  other end-points (hormonal level)
  evaluation of co-exposure effects

 Measures
  precaution
  monitoring: exposures from new technologies, early detection of possible risks (prospective studies)

NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                                                      7
Infrared radiation


 Evidence
 
 

 High exposures, technology development
  infrared “saunas”
 

 Research need
 
 

 Measures
 
 




NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                        8
Visible Light


 Evidence
  burn (skin, eye), eye injuries – retina coagulation (laser)
  photochemical retinal hazard - blue light hazard
  effects on sleep?

 High exposures, technology development
  Laserpointers (up to 5 W), Lasers,
  IPL, cosmetic applications, laser epilation
  LED, lamps

 Research need
  blue light hazard, biological spectral relevance
  night illumination

 Measures
  ban strong laserpointers
  no cosmetic applications for kids


NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                   9
UV Radiation I


    Evidence
     skin cancers (high evidence, risk factors known)
    immunosuppression -> viral infections like herpes simplex (not high evidence), lower
    response by vaccination (hepatitis B, rubela), but might also be protective effect by
    vaccination against tuberculosis
    positive effects (risk reduction due to D-Vitamin or immunosuppresion?) - polymorphic
    light eruption – PLE, multiple sclerosis, asthma, allergies
     photoaging, melanocytic naevi
    effects on eye: phototoxic, photosensitive, photoalergic effets  cancer,
    photokeratitis,cataract
      sensitivity is a function of age – children more sensitive

    Research need
     positive effects and the role of vitamin D
     in-vitro models for children
     UV-sensitivity of children, epidermal stem cells



NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                                         10
UV Radiation


 High exposures, technology development
  Sun, ozone depletion increases skin cancer (20% depl -> 5%more cancers)
  sunbeds

 Measures
  optimal sun-protection? Protect from cancer, but allow D-vitamin (vitamin
 supplementation)
  educational programmes + policy accreditation programs for preprimary school 
 since 1980 in Australia  decreasing of skin cancer incidence from 1995
  sunbed problem!  no sunbed use for children!




NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                                11
Overarching Issues

 Evidence
  combined exposures?
  sensitivity?
 

 High exposures, technology development
 
 

 Research need
  multifactor, multistage effects, cofactors?
 

 Measures
 
 


NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101                   12

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Moser

  • 1. International Conference on Non-Ionizing Radiation and Children’s Health Session 5 – Risk management and Prevention Discussion Mirjana Moser LJubljana, 18-20 Mai 2011 NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 1
  • 2. Are our children today sufficiently protected against NIR? NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 2
  • 3. Are our children today sufficiently protected against NIR? Evidence  What is the level of evidence for particular, children related, risks from NIR?  What level of evidence do a risk manager need? High exposures, technology development  Which are critical / high exposures?  What technology development should we follow in order to anticipate potential future risks for children Research need  What are research priorities? Measures  What protection, precaution measures are feasible and “reasonable”?  What measures have been taken?  What measures should be taken? NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 3
  • 4. Static Electric and Magnetic fields Evidence  Some data on pregnancy and occupational exposures up to ~ 2T  ??? effects for stronger fields High exposures, technology development  MRI - occupational exposure of pregnant women Research need  Effects of static fields > 3T Measures   revision of occupational exposure directive? NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 4
  • 5. ELF EMF Evidence  childhood leukaemia (might be multistage, multifactor effect)  risk for brain cancer (some suggestions)?  no effect on development (animal studies) High exposures (> 0.4 μT), technology development  power lines  household installations and appliances (floor heating, transformers, electric blankets, waterbeds..)  transportation Research need  interdisciplinary research on leukaemia (genetic, animal, epi, different agents) like research programm in Germany (BfS)  big, worldwide prospective studies?  mechanisms (new ideas like radical pair mechanism – RPM)? Measures  precautionary measures mostly considering power lines  precautionary measures for other appliances (no waterbeds for children)?  recommendations or more strict regulations (limits, restrictions)? NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 5
  • 6. Intermediate frequencies EMF Evidence  ???  High exposures, technology development  induction cooker  RFID, EAS  energy saving lamps  wireless power transfer Research need  research need in all disciplines!!  Measures   research programm covering all disciplines NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 6
  • 7. HF-EMF Evidence  brain cancer (CEFALO –in publication, Mobi-Kids starting), no increase in cancer incidence  well-being, cognition, behaviour - some indications, but methodological problems; lifestyle influence, day-time sleepiness because of sending SMS during night  development, teratological effects (animal studies) – no effects  changes in EEG (human)?  animal studies on: brain structure and function – no effect, blood-brain barrier – some effects High exposures, technology development  mobile phones  emerging (telecommunication) technologies? change in exposures? change of lifestyle? Research need  interaction mechanisms (gene expression, mechanistic tumour promoters)  exposures and dosimetry of new technologies  prospective epidemiological studies  other end-points (hormonal level)  evaluation of co-exposure effects Measures  precaution  monitoring: exposures from new technologies, early detection of possible risks (prospective studies) NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 7
  • 8. Infrared radiation Evidence   High exposures, technology development  infrared “saunas”  Research need   Measures   NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 8
  • 9. Visible Light Evidence  burn (skin, eye), eye injuries – retina coagulation (laser)  photochemical retinal hazard - blue light hazard  effects on sleep? High exposures, technology development  Laserpointers (up to 5 W), Lasers,  IPL, cosmetic applications, laser epilation  LED, lamps Research need  blue light hazard, biological spectral relevance  night illumination Measures  ban strong laserpointers  no cosmetic applications for kids NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 9
  • 10. UV Radiation I Evidence  skin cancers (high evidence, risk factors known) immunosuppression -> viral infections like herpes simplex (not high evidence), lower response by vaccination (hepatitis B, rubela), but might also be protective effect by vaccination against tuberculosis positive effects (risk reduction due to D-Vitamin or immunosuppresion?) - polymorphic light eruption – PLE, multiple sclerosis, asthma, allergies  photoaging, melanocytic naevi effects on eye: phototoxic, photosensitive, photoalergic effets  cancer, photokeratitis,cataract sensitivity is a function of age – children more sensitive Research need  positive effects and the role of vitamin D  in-vitro models for children  UV-sensitivity of children, epidermal stem cells NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 10
  • 11. UV Radiation High exposures, technology development  Sun, ozone depletion increases skin cancer (20% depl -> 5%more cancers)  sunbeds Measures  optimal sun-protection? Protect from cancer, but allow D-vitamin (vitamin supplementation)  educational programmes + policy accreditation programs for preprimary school  since 1980 in Australia  decreasing of skin cancer incidence from 1995  sunbed problem!  no sunbed use for children! NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 11
  • 12. Overarching Issues Evidence  combined exposures?  sensitivity?  High exposures, technology development   Research need  multifactor, multistage effects, cofactors?  Measures   NIR&Kids/ Ljubljana / Mirjana Moser / 18-20.05.20101 12