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Foot and Mouth Disese control strategies

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ubio Biotechnology Systems Pvt Ltd
ubio Biotechnology Systems Pvt Ltd
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[object Object],[object Object],V I Bishor & Faisal Siyavudeen ubio Biotechnology Systems Pvt. Ltd Biotechnology Incubation center, Kinfra Hitech Park, Kalamassery, Kochi
Proportions of FMD Virus Serotypes Isolated by the WRLFMD O A C SAT1 SAT2 SAT3 ASIA1 (n=311) 64% 7% 23% 4% 2%
Foot and Mouth Disease Control in Kerala ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
FMD Disease control in Kerala: Proposed measures. ,[object Object],[object Object],[object Object],[object Object]
Clinical surveillance ,[object Object],[object Object],[object Object],[object Object]
Migration Control and Monitoring ,[object Object],[object Object],[object Object],[object Object]
Control of Cross-Border livestock trade. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Early detection measures and epidemic control ,[object Object],[object Object],[object Object],[object Object],[object Object]
FMD control measures: Implementation Challenges. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rapid FMD NSP Testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Practical issues of NSP testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
EU FMD Committee Recommendation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OIE Recommendation (2006) Schematic representation of laboratory tests for determining evidence of FMDV infection through or following serological surveys
Vaccine Quality control ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Differentiation Infected and Vaccinated Animal     Results serology     Conventional test(LPB,VN) FMDV NSP test Vaccinated Infected + + Vaccinated Not infected + - Not vaccinated Infected + + Not vaccinated Not infected - -
Immune response of infected and vaccinated animals (cattle) +ve -ve Result Days after vaccination or infection 4 8 12 16 SP antibodies ( Infected) SP antibodies (Vaccinated) NSP antibodies ( Infected ) NSP antibodies (Vaccinated)
Assay Overview and Usage ,[object Object],[object Object],[object Object],[object Object]
Test procedure NEGATIVE Only control band visible POSITIVE Control and test bands visible INVALID No control line, test is invalid Collect Blood / whole blood assays can be formatted Separate serum Take out the test card from the aluminium foil pouch and place it on a horizontal surface. Add 3 drops of the specimen into sample hole ‘S’ Take 3 drops serum
Ubio QUICKVET FMD NSP test ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recommendation of Kerala ,[object Object],[object Object],[object Object]
Program flow chart for Screening Dairy Animals
Program Flow Chart for Screening Slaughter Animals The practical screening scenario 40 animals/Truck With 3 staff (veterinary doctor and/or livestock inspectors) the total time for one vehicle: 57 minutes. In addition to inspection, the check-post authority will also note animal identification numbers on the issued certificate and on individual animals. ubio can provide custom kits with paired random number identification stickers for this purpose
Vigilance program
[object Object],ubiquitous . biology www.ubio.in

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Foot and Mouth Disese control strategies

  • 1.
  • 2. Proportions of FMD Virus Serotypes Isolated by the WRLFMD O A C SAT1 SAT2 SAT3 ASIA1 (n=311) 64% 7% 23% 4% 2%
  • 3.
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  • 13. OIE Recommendation (2006) Schematic representation of laboratory tests for determining evidence of FMDV infection through or following serological surveys
  • 14.
  • 15. Differentiation Infected and Vaccinated Animal     Results serology     Conventional test(LPB,VN) FMDV NSP test Vaccinated Infected + + Vaccinated Not infected + - Not vaccinated Infected + + Not vaccinated Not infected - -
  • 16. Immune response of infected and vaccinated animals (cattle) +ve -ve Result Days after vaccination or infection 4 8 12 16 SP antibodies ( Infected) SP antibodies (Vaccinated) NSP antibodies ( Infected ) NSP antibodies (Vaccinated)
  • 17.
  • 18. Test procedure NEGATIVE Only control band visible POSITIVE Control and test bands visible INVALID No control line, test is invalid Collect Blood / whole blood assays can be formatted Separate serum Take out the test card from the aluminium foil pouch and place it on a horizontal surface. Add 3 drops of the specimen into sample hole ‘S’ Take 3 drops serum
  • 19.
  • 20.
  • 21. Program flow chart for Screening Dairy Animals
  • 22. Program Flow Chart for Screening Slaughter Animals The practical screening scenario 40 animals/Truck With 3 staff (veterinary doctor and/or livestock inspectors) the total time for one vehicle: 57 minutes. In addition to inspection, the check-post authority will also note animal identification numbers on the issued certificate and on individual animals. ubio can provide custom kits with paired random number identification stickers for this purpose
  • 24.