Organic compounds in the mobile phase have a high impact on thermal conductivity in gas chromatography. The nature, polarity, and volatility of organic materials affect thermal conductivity. Chemical derivatization of organic materials can improve chromatographic performance by enhancing volatility and peak shape, and increasing temperature stability and detection through the introduction of functional groups responsive to thermal electron capture techniques.

1. How do organic materials impact thermal conductivity in gas chromatography?
How do organic materials impact thermal conductivity in gas chromatography?
Solution
The thermal conductivity is a remarkable parameter in gas chromatography. The mobile phase of
organic compounds have a very high impact on the thermal conductivity in the gas
chromatography. The nature of the organic compounds, its extent of polarity and volatility are
the lkey factors responsible for affecting such thermal conductivity. Hence the chemical
derivatization of the organic materials is conducted to improve overall chromatographic
performance as well as enhanced volatility, improved peak shape along with the emperature
stability.
Furthermore such derivatization of the organic materials is very much effective to enhance
detection by introducing functional groups in it allowing the significant, responsive & selective
GC detection based on the thermal electron capture technique.