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Confounders and magicians

Jan Tunér and Lars Hode
Swedish Laser Medical Society

In advertising you will frequently find claims that a product is described as “optimal” or
“ideal”. This is strange, because too often a previous product from the same manufacturer was
optimal, too. So how could it then be improved? Advertising is filled with meaningless words
such as “technology”, “recent”, “proven”. This is all part of the advertising jargon and since it
is not illegal, we will have to live with it. Now and then sheer lies are used. A classical
example is the beauty products tested by “The Swiss Vitamin Institute”. There never was such
an institute…

It is natural that a salesman wants to promote and ultimately sell his product and we cannot as
a customer expect full objectivity. But pushing ones luck too hard will in the end be contra
productive. The laser therapy market is no different from the cosmetic market; there are all
kinds of salesmen ranging from the earnest ones to the sheer liars.

Let us look at some examples.
On “ChiroWeb.com” there is an article where Daniel Murphy, DC discusses an article by Dr.
Wertz (associated with Avicenna Laser Technology Inc). That article it says: World renowned
Laser Therapy Experts, Jan Tunér and Lars Hode have indicated the advantages of high
power laser therapy; “The (research) literature supports the hypothesis that higher power
density yields better clinical results. The Murphy article argues, however, that high energies
are not necessary in laser therapy, and most effects are systemic, so low energies on one side
of a body would also make the other side benefit. Well, the fact that we do have systemic
effects could not be argued, but the extent of it could. The said article goes on:

Several times in his article, Dr. Wertz referenced Tunér and Hode in his support of using
lasers with higher power and dosage, yet he fails to note that Tunér and Hode also make the
following points: “Treatment with laser therapy is not based on heat development but on
photochemical and photo biological effects in cells and tissues. [Lasers] cannot penetrate the
tissue more than a fraction of a millimeter, so there is no other primary responding tissue
other than the outer part of the dermis.”

It is obvious that the Wertz article pleads for higher doses and energies in laser therapy but Dr
Murhpy now tries to argue for the opposite. And so something odd happens! The sentence
“[Lasers] cannot penetrate…indicates that a part of the original sentence has been edited.
And quite some editing, too! Because the original sentence is “CO2 lasers cannot penetrate…”
This is something quite different. Some “[lasers]” can penetrate several cm into tissue depen-
ding on wavelength, type of tissue, power density and treatment technique. By removing
“CO2” the entire meaning of the sentence has been changed 180 degrees. Someone is mani-
pulating the truth.


Now, let us have a look at the web site of the Pegasus laser. This is a 10 Watt “Low level
laser”, arguing the very opposite than the above proponent of very low doses. The advantages
and disadvantages of Class IV lasers in phototherapy can be discussed, but certainly it cannot
be fairly stated that lasers in the watt range generally are superior to those in the milliwatt
range. Each may have a place, given the right conditions and application mode. But there is
something much worse in that web site. According to the web site the 980 nm wavelength has
a superior penetration rate as compared to an 880 nm laser (which probably is supposed to be
an 808 nm laser – one of the most common types, while 880 nm lasers are rare). And further
to that, a 500 mW 808 nm laser is supposed reach only halfway through the skin. The truth is
that the human body is much more transparent at 808 nm than at 980 nm, and even 880 nm
has a greater optical penetration than 980 nm. Because the 980 nm has a lower penetration
capacity, more energy is absorbed in the upper part of the skin and the risk for overheating is
greater. So again, facts are turned around to adapt to sales strategies. The customer is
supposed to be uneducated enough the swallow the bait.

                                                                 Another company that uses
                                                                 the limited knowledge of
                                                                 their potential customers is
                                                                 Avicenna. The company
                                                                 claims that a Class 4 laser
                                                                 is much better than a class
                                                                 3B laser. This is just non-
                                                                 sense. The classification is
                                                                 only regarding the possible
                                                                 risk for eye injuries and has
                                                                 nothing to do with the
                                                                 efficiency in treatment. It
                                                                 was a similar tendency in
                                                                 Europe in the eighties
                                                                 between lasers in class 3A
                                                                 and 3B. The classification
                                                                 is not only a question of
                                                                 output power; it has to do
with wavelength, divergence of the beam, emission area, pulsing etc.

Regarding high power
lasers: it is not so that high
power simply is better
than low power. Looking
at e.g. the dose, there is a
dose window, described
by Arndt-Schulz diagram,
within which the positive
biological effects occur.
See figure beside. With
the stronger lasers it is
easier to give in-optimal
doses and also a greater
risk to burn people on
pigmented skin, dark hair
follicles, tattoos etc. Let
us say that you want to
give a surface of 1 cm2 a
dose of 10 joules/cm2 (quite high dose). With a 10 watt laser this takes one second in treat-
ment time. If you want to give 2 joules to the same are (typical dose), it takes 0.2 seconds.
A certain power is of course necessary, but too much costs just more money and does not give
better results. For most of the about 100 laser producing companies in the world, it is easy to
make strong laser (we regard lasers with output power exceeding 1 watt as unnecessary strong
lasers). Most of them have much more experience in this field than Avicenna and produce
more optimal lasers. Class 4 lasers for phototherapy is not new and not innovative, such lasers
have been on the market for years but used for other indications. Avicenna claims that their
laser reaches down up to 10 cm (four inches) and that not correct.

The above criticism is directed towards the gross generalisations of vendors of Class 4 lasers,
not necessarily against Class 4 laser per se. These lasers in themselves have advantages and
limitations and future research will hopefully pinpoint them.

Our last example can be found on the Erchonia web page. A video demonstrates how a frozen
shoulder is “fixed” within seconds, using a 10 mW diode laser with expanded beam of red
light. Not only that the power density of the beam is very low, the optical penetration through
skin is also low and the dose in J/cm2 is homeopathic. But even worse: the therapy is
performed through the clothes! So in fact, practically no photons reach the skin over the target
area and certainly no photons ever meet the target. Whatever the “magic trick” is, it is not
performed by the laser. The Erchonia Company should contact James Randi and claim his 1
million USD prize. It´s magic!

Laser therapy has been working against the wind for decades. A major reason for the first rise
and fall of laser therapy was the laser hype in the 80ies, when HeNe lasers in the <1 mW
range were marketed. Slowly the positive clinical effects seen have been confirmed in high
quality research and the therapy is gaining scientific credibility. It now appears that another
hype is hitting the United States and it could very well send laser therapy back to the
backyards of the medical clinics, once again. We urge manufacturers and salesmen to stick to
physical facts and scientifically proven claims. This is good enough for selling the medicine
of the future. And to remain on the market even in that future.

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Confounders

  • 1. Confounders and magicians Jan Tunér and Lars Hode Swedish Laser Medical Society In advertising you will frequently find claims that a product is described as “optimal” or “ideal”. This is strange, because too often a previous product from the same manufacturer was optimal, too. So how could it then be improved? Advertising is filled with meaningless words such as “technology”, “recent”, “proven”. This is all part of the advertising jargon and since it is not illegal, we will have to live with it. Now and then sheer lies are used. A classical example is the beauty products tested by “The Swiss Vitamin Institute”. There never was such an institute… It is natural that a salesman wants to promote and ultimately sell his product and we cannot as a customer expect full objectivity. But pushing ones luck too hard will in the end be contra productive. The laser therapy market is no different from the cosmetic market; there are all kinds of salesmen ranging from the earnest ones to the sheer liars. Let us look at some examples. On “ChiroWeb.com” there is an article where Daniel Murphy, DC discusses an article by Dr. Wertz (associated with Avicenna Laser Technology Inc). That article it says: World renowned Laser Therapy Experts, Jan Tunér and Lars Hode have indicated the advantages of high power laser therapy; “The (research) literature supports the hypothesis that higher power density yields better clinical results. The Murphy article argues, however, that high energies are not necessary in laser therapy, and most effects are systemic, so low energies on one side of a body would also make the other side benefit. Well, the fact that we do have systemic effects could not be argued, but the extent of it could. The said article goes on: Several times in his article, Dr. Wertz referenced Tunér and Hode in his support of using lasers with higher power and dosage, yet he fails to note that Tunér and Hode also make the following points: “Treatment with laser therapy is not based on heat development but on photochemical and photo biological effects in cells and tissues. [Lasers] cannot penetrate the tissue more than a fraction of a millimeter, so there is no other primary responding tissue other than the outer part of the dermis.” It is obvious that the Wertz article pleads for higher doses and energies in laser therapy but Dr Murhpy now tries to argue for the opposite. And so something odd happens! The sentence “[Lasers] cannot penetrate…indicates that a part of the original sentence has been edited. And quite some editing, too! Because the original sentence is “CO2 lasers cannot penetrate…” This is something quite different. Some “[lasers]” can penetrate several cm into tissue depen- ding on wavelength, type of tissue, power density and treatment technique. By removing “CO2” the entire meaning of the sentence has been changed 180 degrees. Someone is mani- pulating the truth. Now, let us have a look at the web site of the Pegasus laser. This is a 10 Watt “Low level laser”, arguing the very opposite than the above proponent of very low doses. The advantages and disadvantages of Class IV lasers in phototherapy can be discussed, but certainly it cannot be fairly stated that lasers in the watt range generally are superior to those in the milliwatt range. Each may have a place, given the right conditions and application mode. But there is
  • 2. something much worse in that web site. According to the web site the 980 nm wavelength has a superior penetration rate as compared to an 880 nm laser (which probably is supposed to be an 808 nm laser – one of the most common types, while 880 nm lasers are rare). And further to that, a 500 mW 808 nm laser is supposed reach only halfway through the skin. The truth is that the human body is much more transparent at 808 nm than at 980 nm, and even 880 nm has a greater optical penetration than 980 nm. Because the 980 nm has a lower penetration capacity, more energy is absorbed in the upper part of the skin and the risk for overheating is greater. So again, facts are turned around to adapt to sales strategies. The customer is supposed to be uneducated enough the swallow the bait. Another company that uses the limited knowledge of their potential customers is Avicenna. The company claims that a Class 4 laser is much better than a class 3B laser. This is just non- sense. The classification is only regarding the possible risk for eye injuries and has nothing to do with the efficiency in treatment. It was a similar tendency in Europe in the eighties between lasers in class 3A and 3B. The classification is not only a question of output power; it has to do with wavelength, divergence of the beam, emission area, pulsing etc. Regarding high power lasers: it is not so that high power simply is better than low power. Looking at e.g. the dose, there is a dose window, described by Arndt-Schulz diagram, within which the positive biological effects occur. See figure beside. With the stronger lasers it is easier to give in-optimal doses and also a greater risk to burn people on pigmented skin, dark hair follicles, tattoos etc. Let us say that you want to give a surface of 1 cm2 a dose of 10 joules/cm2 (quite high dose). With a 10 watt laser this takes one second in treat- ment time. If you want to give 2 joules to the same are (typical dose), it takes 0.2 seconds.
  • 3. A certain power is of course necessary, but too much costs just more money and does not give better results. For most of the about 100 laser producing companies in the world, it is easy to make strong laser (we regard lasers with output power exceeding 1 watt as unnecessary strong lasers). Most of them have much more experience in this field than Avicenna and produce more optimal lasers. Class 4 lasers for phototherapy is not new and not innovative, such lasers have been on the market for years but used for other indications. Avicenna claims that their laser reaches down up to 10 cm (four inches) and that not correct. The above criticism is directed towards the gross generalisations of vendors of Class 4 lasers, not necessarily against Class 4 laser per se. These lasers in themselves have advantages and limitations and future research will hopefully pinpoint them. Our last example can be found on the Erchonia web page. A video demonstrates how a frozen shoulder is “fixed” within seconds, using a 10 mW diode laser with expanded beam of red light. Not only that the power density of the beam is very low, the optical penetration through skin is also low and the dose in J/cm2 is homeopathic. But even worse: the therapy is performed through the clothes! So in fact, practically no photons reach the skin over the target area and certainly no photons ever meet the target. Whatever the “magic trick” is, it is not performed by the laser. The Erchonia Company should contact James Randi and claim his 1 million USD prize. It´s magic! Laser therapy has been working against the wind for decades. A major reason for the first rise and fall of laser therapy was the laser hype in the 80ies, when HeNe lasers in the <1 mW range were marketed. Slowly the positive clinical effects seen have been confirmed in high quality research and the therapy is gaining scientific credibility. It now appears that another hype is hitting the United States and it could very well send laser therapy back to the backyards of the medical clinics, once again. We urge manufacturers and salesmen to stick to physical facts and scientifically proven claims. This is good enough for selling the medicine of the future. And to remain on the market even in that future.