Role of piracetam in post concussion syndrome

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All India Institute of Medical Sciences

Health & Medicine

ROLE OF PIRACETAM IN POST-CONCUSSION SYNDROME A PROSPECTIVE RANDOMIZED STUDY Deepak Agrawal, K Naveen* Departments of Neurosurgery* and Nuclear medicine*, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, INDIA

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PIRACETAM IN MINOR HEAD INJURY PREVIOUS STUDIES ON PIRACETAM IN MINOR HEAD INJURY WERE BASED ONLY ON ‘SUBJECTIVE CRITERIA’ FIRST STUDY OF ITS KIND BASED ON AN OBJECTIVE PARAMETER LIKE BRAIN SPECT

PIRACETAM IN MINOR HEAD INJURY SENSTIVITY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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PIRACETAM IN MINOR HEAD INJURY ,[object Object],[object Object],[object Object],MINOR HEAD INJURY [criteria published by the members of the Mild Traumatic brain injury Interdisciplinary Special Interest Group (BISIG)] Kay T, Harrington DE, et al. Definition of mild traumatic brain injury. J Head Trauma Rehabil 1993;8:86

PIRACETAM IN MINOR HEAD INJURY ,[object Object],[object Object],[object Object],[object Object],POST CONCUSSION SYNDROME: (2 or more of the following) DSM IV criteria based on recommendation of Brown et al. Brown SJ, Fann JR, Grant I: Postconcussion disorder: time to acknowledge a common source of neurobehavioural morbidity. J Neuropsychiatry Clin Neurosci 6:15-22, 1994

PIRACETAM IN MINOR HEAD INJURY MATERIALS AND METHODS (Contd.) ,[object Object],INVESTIGATION ,[object Object],[object Object]

PIRACETAM IN MINOR HEAD INJURY ,[object Object],[object Object],SPECT

PIRACETAM IN MINOR HEAD INJURY ,[object Object],ABNORMAL SPECT SCAN

PIRACETAM IN MINOR HEAD INJURY MATERIALS AND METHODS (Contd.)

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PIRACETAM IN MINOR HEAD INJURY ,[object Object],CONCLUSIONS (Contd.) A RANDOMISED CONTROLLED TRIAL IS PRESENTLY UNDERWAY FOR MORE DEFINITIVE RESULTS

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