Ce diaporama a bien été signalé.
Nous utilisons votre profil LinkedIn et vos données d’activité pour vous proposer des publicités personnalisées et pertinentes. Vous pouvez changer vos préférences de publicités à tout moment.
Vitamin  D Its More Important then you Think By  Adam Rinde, ND
Vitamin D <ul><li>What is It? </li></ul><ul><li>What happens if I have a deficiency? </li></ul><ul><li>What types of condi...
Vitamin D <ul><li>Acts as a hormone and nutrient </li></ul><ul><li>Calciferol (D2) is the storage form </li></ul><ul><li>C...
Vitamin D <ul><li>Vitamin D fits the definition of a hormone because it can be produced by the body, has specific  tissue ...
Vitamin D <ul><li>More then 50 genes are known to be transcribed by Vitamin D </li></ul><ul><li>Involved in Calcium and Ph...
Vitamin D Metabolism
Sources of Vitamin D <ul><li>Salmon (3.5 oz): Fresh, wild (600-1000 IU of Vitamin D3) </li></ul><ul><li>Fresh Farmed Salmo...
Sources of Vitamin D <ul><li>Mackerel, canned (3.5 oz):250 IU of D3 </li></ul><ul><li>Tuna, canned (3.6 oz): 230 IU of D3 ...
Absorption of Dietary Vitamin D <ul><li>Bile Salts form Micelle </li></ul><ul><li>Vitamin D is passively diffused across t...
Regulation of Vitamin d
Rate Limiting Factors of Vitamin D3 activation <ul><li>Calcitriol formation in the kidney dependent on another rNADPH depe...
Functions and Mechanisms of Aciton <ul><li>Vitamin D acts on the following tissues </li></ul><ul><ul><li>intestine, bone, ...
Vitamin D and the cell receptor
Interactions with other Nutrients <ul><li>Calcium </li></ul><ul><li>Phosphorous </li></ul><ul><li>Vitamin K </li></ul>
Defficiencies <ul><li>Rickets </li></ul><ul><li>Osteopmalacia </li></ul>
Risk Factors for Defficiency <ul><li>Elderly Populations </li></ul><ul><li>Northern Latitutudes </li></ul><ul><li>People o...
Signs and Symptoms of Defficiency <ul><li>Bone Pain </li></ul><ul><li>Osteopenia </li></ul><ul><li>Osteoporosis </li></ul>
Side Effects and Interactions <ul><li>one published report of toxicity at  40,000 IU’s of Vitamin D3 daily. </li></ul><ul>...
contraindications <ul><li>Sarcoidosis when elevated calcium levels are present </li></ul>
Assessment of Nututriture <ul><li>Plasma Concentration of 25-OH Vitamin D3 (Calcidiol) </li></ul><ul><li>However some chol...
Therapeutic Use of Prescription Dose Vitamin D <ul><li>Psorasis (Dovonex), Topical  </li></ul><ul><li>Vitiligo (Dovonex/Ca...
Therapeutic Use <ul><li>Depression </li></ul><ul><li>Type I Diabetes </li></ul><ul><li>Type II Diabetes </li></ul>
Therapeutic Use to prevent or replace defficieny <ul><li>Chron’s Disease </li></ul><ul><li>Celiac Disease </li></ul><ul><l...
Vitamin D as Complementary Medicine <ul><li>Chron’s Disease to prevent osteopmalaxia </li></ul>
Vitamin D for Prevention <ul><li>Breast Cancer </li></ul><ul><li>Colon Cancer </li></ul>
Prochain SlideShare
Chargement dans…5
×

Vitamin D

11 738 vues

Publié le

Publié dans : Santé & Médecine
  • DOWNLOAD FULL BOOKS, INTO AVAILABLE FORMAT ......................................................................................................................... ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... ......................................................................................................................... ......................................................................................................................... .............. Browse by Genre Available eBooks ......................................................................................................................... Art, Biography, Business, Chick Lit, Children's, Christian, Classics, Comics, Contemporary, Cookbooks, Crime, Ebooks, Fantasy, Fiction, Graphic Novels, Historical Fiction, History, Horror, Humor And Comedy, Manga, Memoir, Music, Mystery, Non Fiction, Paranormal, Philosophy, Poetry, Psychology, Religion, Romance, Science, Science Fiction, Self Help, Suspense, Spirituality, Sports, Thriller, Travel, Young Adult,
       Répondre 
    Voulez-vous vraiment ?  Oui  Non
    Votre message apparaîtra ici
  • DOWNLOAD FULL BOOKS, INTO AVAILABLE Format, ......................................................................................................................... ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... ......................................................................................................................... ......................................................................................................................... .............. Browse by Genre Available eBooks ......................................................................................................................... Art, Biography, Business, Chick Lit, Children's, Christian, Classics, Comics, Contemporary, Cookbooks, Crime, Ebooks, Fantasy, Fiction, Graphic Novels, Historical Fiction, History, Horror, Humor And Comedy, Manga, Memoir, Music, Mystery, Non Fiction, Paranormal, Philosophy, Poetry, Psychology, Religion, Romance, Science, Science Fiction, Self Help, Suspense, Spirituality, Sports, Thriller, Travel, Young Adult,
       Répondre 
    Voulez-vous vraiment ?  Oui  Non
    Votre message apparaîtra ici
  • DOWNLOAD FULL BOOKS, INTO AVAILABLE FORMAT ......................................................................................................................... ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... ......................................................................................................................... ......................................................................................................................... .............. Browse by Genre Available eBooks ......................................................................................................................... Art, Biography, Business, Chick Lit, Children's, Christian, Classics, Comics, Contemporary, Cookbooks, Crime, Ebooks, Fantasy, Fiction, Graphic Novels, Historical Fiction, History, Horror, Humor And Comedy, Manga, Memoir, Music, Mystery, Non Fiction, Paranormal, Philosophy, Poetry, Psychology, Religion, Romance, Science, Science Fiction, Self Help, Suspense, Spirituality, Sports, Thriller, Travel, Young Adult,
       Répondre 
    Voulez-vous vraiment ?  Oui  Non
    Votre message apparaîtra ici
  • The Only Holistic System In Existence That Will Show You How To Cure Your Acne, End The Breakouts, Regain Your Natural Inner Balance and Achieve The Lasting Clear Skin You Deserve! ➤➤ http://scamcb.com/buk028959/pdf
       Répondre 
    Voulez-vous vraiment ?  Oui  Non
    Votre message apparaîtra ici
  • DOWNLOAD FULL BOOKS, INTO AVAILABLE FORMAT ......................................................................................................................... ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. PDF EBOOK here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. EPUB Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... 1.DOWNLOAD FULL. doc Ebook here { https://tinyurl.com/y6a5rkg5 } ......................................................................................................................... ......................................................................................................................... ......................................................................................................................... .............. Browse by Genre Available eBooks ......................................................................................................................... Art, Biography, Business, Chick Lit, Children's, Christian, Classics, Comics, Contemporary, Cookbooks, Crime, Ebooks, Fantasy, Fiction, Graphic Novels, Historical Fiction, History, Horror, Humor And Comedy, Manga, Memoir, Music, Mystery, Non Fiction, Paranormal, Philosophy, Poetry, Psychology, Religion, Romance, Science, Science Fiction, Self Help, Suspense, Spirituality, Sports, Thriller, Travel, Young Adult,
       Répondre 
    Voulez-vous vraiment ?  Oui  Non
    Votre message apparaîtra ici

Vitamin D

  1. 1. Vitamin D Its More Important then you Think By Adam Rinde, ND
  2. 2. Vitamin D <ul><li>What is It? </li></ul><ul><li>What happens if I have a deficiency? </li></ul><ul><li>What types of conditions are treated with vitamin D? </li></ul><ul><li>How can I find out if I am defficient? </li></ul><ul><li>How much do I need to take? </li></ul>
  3. 3. Vitamin D <ul><li>Acts as a hormone and nutrient </li></ul><ul><li>Calciferol (D2) is the storage form </li></ul><ul><li>Cholecalciferol (D3) is the active form </li></ul>
  4. 4. Vitamin D <ul><li>Vitamin D fits the definition of a hormone because it can be produced by the body, has specific tissue targets, and does not have to be supplied by the diet </li></ul><ul><li>It is categorized as a Fat Soluble Vitamin </li></ul>
  5. 5. Vitamin D <ul><li>More then 50 genes are known to be transcribed by Vitamin D </li></ul><ul><li>Involved in Calcium and Phosphate Metabolism And Absorption </li></ul><ul><li>Enhances Bone Development </li></ul><ul><li>differentioation, proliferation, and tissue growth in many tissues including (skin, muscles, pancreas, nerves, the parathyroid gland, and the immune system) </li></ul>
  6. 6. Vitamin D Metabolism
  7. 7. Sources of Vitamin D <ul><li>Salmon (3.5 oz): Fresh, wild (600-1000 IU of Vitamin D3) </li></ul><ul><li>Fresh Farmed Salmon (3.5 oz): about 100-250 IU of D3 or D2 </li></ul><ul><li>Canned salmon (3.5 oz): 300-600 IU of Vitamin D3 </li></ul><ul><li>Sardines, canned (3.5 oz):about 300 IU of Vitamin D3 </li></ul><ul><li>[1] Holick,Michael. 2007. Vitamin D Deficiency. N Engl J Med 2007;357:266-81ral Sources </li></ul>
  8. 8. Sources of Vitamin D <ul><li>Mackerel, canned (3.5 oz):250 IU of D3 </li></ul><ul><li>Tuna, canned (3.6 oz): 230 IU of D3 </li></ul><ul><li>Shitake Mushrooms (Fresh): 3.5 oz about 100 IU of D2 </li></ul><ul><li>Shitake Mushroom (sun-dried): 3.5 oz about 1600 IU of D2 </li></ul><ul><li>Exposure to sunlight (UVB) radiation .5 minimal erythemal dose about 3000 IU of Vitamin D3 [1] </li></ul>
  9. 9. Absorption of Dietary Vitamin D <ul><li>Bile Salts form Micelle </li></ul><ul><li>Vitamin D is passively diffused across the intestine </li></ul><ul><li>Absorbed in Small Intestine </li></ul>
  10. 10. Regulation of Vitamin d
  11. 11. Rate Limiting Factors of Vitamin D3 activation <ul><li>Calcitriol formation in the kidney dependent on another rNADPH dependent enzyme, 25, OH- Ds, 1-hydroxylase (1-monooxygenase) a mitochondrial mixed-function oxidase. An enzyme also present in macrophages and some cnacer cells </li></ul><ul><li>It is influenced by PTH, and low plasma calcium concentrations, and eh concentration of 1,25 (OH)2 D3 Calcitriol. </li></ul><ul><li>Dietary Phophorous intake will aslo imprair activity </li></ul>
  12. 12. Functions and Mechanisms of Aciton <ul><li>Vitamin D acts on the following tissues </li></ul><ul><ul><li>intestine, bone, kidney, and now believed to also act on cardiac, muscle, brain, skin, hematopoietic, and immune clls amongh others </li></ul></ul><ul><ul><li>Related to the function of cell nifferentioation. </li></ul></ul><ul><ul><li>Nuclear recptors fin over 30 organs have been found for Vitamin D </li></ul></ul><ul><ul><li>stimulates calcium reabsorption and absorption </li></ul></ul><ul><ul><li>stimulates phosphorus absorption. </li></ul></ul>
  13. 13. Vitamin D and the cell receptor
  14. 14. Interactions with other Nutrients <ul><li>Calcium </li></ul><ul><li>Phosphorous </li></ul><ul><li>Vitamin K </li></ul>
  15. 15. Defficiencies <ul><li>Rickets </li></ul><ul><li>Osteopmalacia </li></ul>
  16. 16. Risk Factors for Defficiency <ul><li>Elderly Populations </li></ul><ul><li>Northern Latitutudes </li></ul><ul><li>People of Color </li></ul><ul><li>Intestinal Bowel Disorders </li></ul><ul><li>Disorders of Parathyroid, Liver, or Kidney </li></ul><ul><li>Anticonvulsant Drug Therapy </li></ul>
  17. 17. Signs and Symptoms of Defficiency <ul><li>Bone Pain </li></ul><ul><li>Osteopenia </li></ul><ul><li>Osteoporosis </li></ul>
  18. 18. Side Effects and Interactions <ul><li>one published report of toxicity at 40,000 IU’s of Vitamin D3 daily. </li></ul><ul><li>may raise blood cholesterol </li></ul><ul><li>Side effects reported: dizziness, naseau, headaches, weight loss, </li></ul><ul><li>Rare: excessive Vitamin D may lead to increased thirst, blindness, deafness, hearing loss, increase urination, diarhhea,and irritability </li></ul>
  19. 19. contraindications <ul><li>Sarcoidosis when elevated calcium levels are present </li></ul>
  20. 20. Assessment of Nututriture <ul><li>Plasma Concentration of 25-OH Vitamin D3 (Calcidiol) </li></ul><ul><li>However some cholecalciferol is stored in fat and muscles. </li></ul>
  21. 21. Therapeutic Use of Prescription Dose Vitamin D <ul><li>Psorasis (Dovonex), Topical </li></ul><ul><li>Vitiligo (Dovonex/Calipotriol) </li></ul><ul><li>Osteoporosis (1000 IU/day) </li></ul><ul><li>Osteopmalacia </li></ul><ul><li>Rickets </li></ul><ul><li>Polycystic Ovarian Syndrome </li></ul><ul><li>Chronic Pain </li></ul><ul><li>Multiple Sclerosis (???) </li></ul><ul><li>Prostate Cancer </li></ul><ul><li>Renal Failure </li></ul><ul><li>Hypoparathyroidsm </li></ul><ul><li>Seasonal Affect Disorder </li></ul>
  22. 22. Therapeutic Use <ul><li>Depression </li></ul><ul><li>Type I Diabetes </li></ul><ul><li>Type II Diabetes </li></ul>
  23. 23. Therapeutic Use to prevent or replace defficieny <ul><li>Chron’s Disease </li></ul><ul><li>Celiac Disease </li></ul><ul><li>Cystic Fibrosis </li></ul>
  24. 24. Vitamin D as Complementary Medicine <ul><li>Chron’s Disease to prevent osteopmalaxia </li></ul>
  25. 25. Vitamin D for Prevention <ul><li>Breast Cancer </li></ul><ul><li>Colon Cancer </li></ul>

×